Search Results - "WIGGALL, Kenneth" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

by Okoye-Okafor, Ujunwa C, Bartholdy, Boris, Cartier, Jessy, Gao, Enoch N, Pietrak, Beth, Rendina, Alan R, Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Kenneth J, Reif, Alexander J, Schmidt, Stanley J, Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-Savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Groy, Arthur, Narayanagari, Swathi-Rao, Antony-Debre, Iléana, Mitchell, Kelly, Wang, Heng Rui, Kao, Yun-Ruei, Christopeit, Maximilian, Carvajal, Luis, Barreyro, Laura, Paietta, Elisabeth, Makishima, Hideki, Will, Britta, Concha, Nestor, Adams, Nicholas D, Schwartz, Benjamin, McCabe, Michael T, Maciejewski, Jaroslav, Verma, Amit, Steidl, Ulrich
Published in Nature chemical biology (01.11.2015)

Get full text

Journal Article

3-(1,1-Dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase

3-(1,1-Dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase

by Tedesco, Rosanna, Shaw, Antony N, Bambal, Ramesh, Chai, Deping, Concha, Nestor O, Darcy, Michael G, Dhanak, Dashyant, Fitch, Duke M, Gates, Adam, Gerhardt, Warren G, Halegoua, Dina L, Han, Chao, Hofmann, Glenn A, Johnston, Victor K, Kaura, Arun C, Liu, Nannan, Keenan, Richard M, Lin-Goerke, Juili, Sarisky, Robert T, Wiggall, Kenneth J, Zimmerman, Michael N, Duffy, Kevin J
Published in Journal of medicinal chemistry (09.02.2006)

Get full text

Journal Article

Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase

Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase

by Shaw, Antony N., Tedesco, Rosanna, Bambal, Ramesh, Chai, Deping, Concha, Nestor O., Darcy, Michael G., Dhanak, Dashyant, Duffy, Kevin J., Fitch, Duke M., Gates, Adam, Johnston, Victor K., Keenan, Richard M., Lin-Goerke, Juili, Liu, Nannan, Sarisky, Robert T., Wiggall, Kenneth J., Zimmerman, Michael N.
Published in Bioorganic & medicinal chemistry letters (01.08.2009)

Get full text

Journal Article

Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors

Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors

by Tedesco, Rosanna, Chai, Deping, Darcy, Michael G., Dhanak, Dashyant, Fitch, Duke M., Gates, Adam, Johnston, Victor K., Keenan, Richard M., Lin-Goerke, Juili, Sarisky, Robert T., Shaw, Antony N., Valko, Klara L., Wiggall, Kenneth J., Zimmerman, Michael N., Duffy, Kevin J.
Published in Bioorganic & medicinal chemistry letters (01.08.2009)

Get full text

Journal Article

Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 1. Discovery and Optimization of Salicylaldehyde Thiosemicarbazone Thrombopoietin Mimics

Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 1. Discovery and Optimization of Salicylaldehyde Thiosemicarbazone Thrombopoietin Mimics

by Duffy, Kevin J, Shaw, Anthony N, Delorme, Evelyne, Dillon, Susan B, Erickson-Miller, Connie, Giampa, Leslie, Huang, Yifang, Keenan, Richard M, Lamb, Peter, Liu, Nannan, Miller, Stephen G, Price, Alan T, Rosen, Jon, Smith, Heather, Wiggall, Kenneth J, Zhang, Lihua, Luengo, Juan I
Published in Journal of medicinal chemistry (15.08.2002)

Get full text

Journal Article

Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 2. Rational Design of Naphtho[1,2-d]imidazole Thrombopoietin Mimics

Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 2. Rational Design of Naphtho[1,2-d]imidazole Thrombopoietin Mimics

by Duffy, Kevin J, Price, Alan T, Delorme, Evelyne, Dillon, Susan B, Duquenne, Celine, Erickson-Miller, Connie, Giampa, Leslie, Huang, Yifang, Keenan, Richard M, Lamb, Peter, Liu, Nannan, Miller, Stephen G, Rosen, Jon, Shaw, Anthony N, Smith, Heather, Wiggall, Kenneth J, Zhang, Lihua, Luengo, Juan I
Published in Journal of medicinal chemistry (15.08.2002)

Get full text

Journal Article

Hydrazinonaphthalene and Azonaphthalene Thrombopoietin Mimics Are Nonpeptidyl Promoters of Megakaryocytopoiesis

Hydrazinonaphthalene and Azonaphthalene Thrombopoietin Mimics Are Nonpeptidyl Promoters of Megakaryocytopoiesis

by Duffy, Kevin J, Darcy, Michael G, Delorme, Evelyne, Dillon, Susan B, Eppley, Daniel F, Erickson-Miller, Connie, Giampa, Leslie, Hopson, Christopher B, Huang, Yifang, Keenan, Richard M, Lamb, Peter, Leong, Lynnette, Liu, Nannan, Miller, Stephen G, Price, Alan T, Rosen, Jon, Shah, Rakhi, Shaw, Tony N, Smith, Heather, Stark, Kenneth C, Tian, Shin-Shay, Tyree, Curtis, Wiggall, Kenneth J, Zhang, Lily, Luengo, Juan I
Published in Journal of medicinal chemistry (25.10.2001)

Get full text

Journal Article

Reversible inhibitors of the gastric (H+/K+)-ATPase. 3. 3-Substituted-4-(phenylamino)quinolines

Reversible inhibitors of the gastric (H+/K+)-ATPase. 3. 3-Substituted-4-(phenylamino)quinolines

by Ife, Robert J, Brown, Thomas H, Keeling, David J, Leach, Colin A, Meeson, Malcolm L, Parsons, Michael E, Reavill, David R, Theobald, Colin J, Wiggall, Kenneth J
Published in Journal of medicinal chemistry (01.09.1992)

Get full text

Journal Article

Reversible inhibitors of the gastric (H+/K+)-ATPase. 2. 1-Arylpyrrolo[3,2-c]quinolines: effect of the 4-substituent

Reversible inhibitors of the gastric (H+/K+)-ATPase. 2. 1-Arylpyrrolo[3,2-c]quinolines: effect of the 4-substituent

by Leach, Colin A, Brown, Thomas H, Ife, Robert J, Keeling, David J, Laing, Shiona M, Parsons, Michael E, Price, Carolyn A, Wiggall, Kenneth J
Published in Journal of medicinal chemistry (01.05.1992)

Get full text

Journal Article

Reversible Inhibitors of the Gastric (H+/K+)-ATPase. 4. Identification of an Inhibitor with an Intermediate Duration of Action

Reversible Inhibitors of the Gastric (H+/K+)-ATPase. 4. Identification of an Inhibitor with an Intermediate Duration of Action

by Leach, Colin A, Brown, Thomas H, Ife, Robert J, Keeling, David J, Parsons, Michael E, Theobald, Colin J, Wiggall, Kenneth J
Published in Journal of medicinal chemistry (01.07.1995)

Get full text

Journal Article

Reversible inhibitors of the gastric (H+/K+)-ATPase. 1. 1-Aryl-4-methylpyrrolo[3,2-c]quinolines as conformationally restrained analogs of 4-(arylamino)quinolines

Reversible inhibitors of the gastric (H+/K+)-ATPase. 1. 1-Aryl-4-methylpyrrolo[3,2-c]quinolines as conformationally restrained analogs of 4-(arylamino)quinolines

by Brown, Thomas H, Ife, Robert J, Keeling, David J, Laing, Shiona M, Leach, Colin A, Parsons, Michael E, Price, Carolyn A, Reavill, David R, Wiggall, Kenneth J
Published in Journal of medicinal chemistry (01.02.1990)

Get full text

Journal Article

New IDH1 mutant inhibitors for treatment of acute myeloid leukemiaf

New IDH1 mutant inhibitors for treatment of acute myeloid leukemiaf

by Okoye-oka, Ujunwa C, Bartholdy, Boris, Cartier, Jessy, Gao, Enoch N, Pietrak, Beth, Rendina, Alan R, Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Kenneth J, Reif, Alexander J, Schmidt, Stanley J, Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Groy, Arthur, Narayanagari, Swathi-rao, Antony-debre, Iléana, Mitchell, Kelly, Wang, Heng Rui, Kao, Yun-ruei, Christopeit, Maximilian, Carvajal, Luis, Barreyro, Laura, Paietta, Elisabeth, Makishima, Hideki, Will, Britta, Concha, Nestor, Adams, Nicholas D, Schwartz, Benjamin, Mccabe, Michael T, Maciejewski, Jaroslav, Verma, Amit, Steidl, Ulrich
Published in Nature chemical biology (01.11.2015)

Get full text

Journal Article

Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia

Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia

by Okoye-Okafor, Ujunwa C., Bartholdy, Boris, Cartier, Jessy, Gao, Enoch, Pietrak, Beth, Rendina, Alan R., Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Kenneth J., Reif, Alexander J., Schmidt, Stanley J., Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-Savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Groy, Arthur, Narayanagari, Swathi-Rao, Antony-Debre, Ileana, Mitchell, Kelly, Wang, Heng Rui, Kao, Yun-Ruei, Christopeit, Maximilian, Carvajal, Luis, Barreyro, Laura, Paietta, Elisabeth, Makishima, Hideki, Will, Britta, Concha, Nestor, Adams, Nicholas D., Schwartz, Benjamin, McCabe, Michael T., Maciejewski, Jaroslav, Verma, Amit, Steidl, Ulrich
Published in Nature chemical biology (05.10.2015)

Get full text

Journal Article

Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzo-thiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors

Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzo-thiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors

by TEDESCO, Rosanna, DEPING CHAI, SHAW, Antony N, VALKO, Klara L, WIGGALL, Kenneth J, ZIMMERMAN, Michael N, DUFFY, Kevin J, DARCY, Michael G, DHANAK, Dashyant, FITCH, Duke M, GATES, Adam, JOHNSTON, Victor K, KEENAN, Richard M, LIN-GOERKE, Juili, SARISKY, Robert T
Published in Bioorganic & medicinal chemistry letters (2009)

Get full text

Journal Article

Prolyl Hydroxylase Inhibitors

Prolyl Hydroxylase Inhibitors

by DUFFY, Kevin J, SHAW, Antony N, WIGGALL, Kenneth, JIN, Jian, LIU, Ronggang, FITCH, Duke M
Year of Publication 20.07.2023

Get full text

Patent

Prolyl hydroxylase inhibitors

Prolyl hydroxylase inhibitors

by Jin, Jian, Fitch, Duke M, Liu, Ronggang, Duffy, Kevin J, Wiggall, Kenneth, Shaw, Antony N
Year of Publication 09.05.2023

Get full text

Patent

TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS

TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS

by REIF, Alexander, BOTYANSZKI, Janos, ZHANG, Daohua, RAMANJULU, Joshi, WIGGALL, Kenneth, CHARNLEY, Adam, KING, Bryan, NEWLANDER, Kenneth, DONG, Xiaoyang, HUMPHREYS, Philip, MARCUS, Kimberly, PERO, Joseph, RAHMAN, Attiq
Year of Publication 25.04.2024

Get full text

Patent

Discovery of SB-497115, a Small-Molecule Thrombopoietin (TPO) Receptor Agonist for the Treatment of Thrombocytopenia

Discovery of SB-497115, a Small-Molecule Thrombopoietin (TPO) Receptor Agonist for the Treatment of Thrombocytopenia

by Luengo, Juan I., Duffy, Kevin J., Shaw, Anthony N., Delorme, Evelyne, Wiggall, Kenneth J., Giampa, Leslie, Liu, Nannan, Smith, Heather, Tian, Shin-Shay, Miller, Stephen G., Keenan, Richard M., Rosen, Jon, Dillon, Susan B., Lamb, Peter, Erickson-Miller, Connie L.
Published in Blood (16.11.2004)

Get full text

Journal Article

Prolyl Hydroxylase Inhibitors

Prolyl Hydroxylase Inhibitors

by Duffy, Kevin J, SHAW, Antony N, WIGGALL, Kenneth, JIN, Jian, LIU, Ronggang, FITCH, Duke M
Year of Publication 11.11.2021

Get full text

Patent

TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS

TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS

by RAHMAN(Deceased), Attiq, BOTYANSZKI, Janos, MARCUS, Kimberly Katherine, ZHANG, Daohua, REIF, Alexander Joseph, RAMANJULU, Joshi, WIGGALL, Kenneth, HUMPHREYS, Philip Gareth, NEWLANDER, Kenneth Allen, DONG, Xiaoyang, CHARNLEY, Adam K, KING, Bryan Wayne, PERO, Joseph
Year of Publication 11.07.2024

Get full text

Patent

1
2
3
4
5
6
7
8
9
10
11
Next
[11]