Dabigatran etexilate--a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity
van Ryn, Joanne, Stangier, Joachim, Haertter, Sebastian, Liesenfeld, Karl-Heinz, Wienen, Wolfgang, Feuring, Martin, Clemens, Andreas
Published in Thrombosis and haemostasis (01.06.2010)
Published in Thrombosis and haemostasis (01.06.2010)
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In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate
Wienen, Wolfgang, Stassen, Jean-Marie, Priepke, Henning, Ries, Uwe Joerg, Hauel, Norbert
Published in Thrombosis and haemostasis (01.07.2007)
Published in Thrombosis and haemostasis (01.07.2007)
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Structure-Based Design of Novel Potent Nonpeptide Thrombin Inhibitors
Hauel, Norbert H, Nar, Herbert, Priepke, Henning, Ries, Uwe, Stassen, Jean-Marie, Wienen, Wolfgang
Published in Journal of medicinal chemistry (25.04.2002)
Published in Journal of medicinal chemistry (25.04.2002)
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Effects of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate, on thrombus formation and bleeding time in rats
Wienen, Wolfgang, Stassen, Jean-Marie, Priepke, Henning, Ries, Uwe Joerg, Hauel, Norbert
Published in Thrombosis and haemostasis (01.08.2007)
Published in Thrombosis and haemostasis (01.08.2007)
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In Vitro and in Vivo Characterization of the Activity of Telmisartan: An Insurmountable Angiotensin II Receptor Antagonist
Maillard, Marc P, Perregaux, Christine, Centeno, Catherine, Stangier, Joachim, Wienen, Wolfgang, Brunner, Hans-R, Burnier, Michel
Published in The Journal of pharmacology and experimental therapeutics (01.09.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2002)
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Heterocyclic thrombin inhibitors. Part 2: quinoxalinone derivatives as novel, potent antithrombotic agents
Ries, Uwe J., Priepke, Henning W.M., Hauel, Norbert H., Handschuh, Sandra, Mihm, Gerhard, Stassen, Jean M., Wienen, Wolfgang, Nar, Herbert
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
Published in Bioorganic & medicinal chemistry letters (21.07.2003)
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The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist : BIBP3226
RUDOLF, K, EBERLEIN, W, ENGEL, W, WIELAND, H. A, WILLIM, K. D, ENTZEROTH, M, WIENEN, W, BECK-SICKINGER, A. G, DOODS, H. N
Published in European journal of pharmacology (27.12.1994)
Published in European journal of pharmacology (27.12.1994)
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Characterization and comparative evaluation of a novel PAI-1 inhibitor
Gils, Ann, Stassen, Jean-Marie, Nar, Herbert, Kley, Joerg T, Wienen, Wolfgang, Ries, Uwe J, Declerck, Paul J
Published in Thrombosis and haemostasis (01.07.2002)
Published in Thrombosis and haemostasis (01.07.2002)
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Comparative antihypertensive and renoprotective effects of telmisartan and lisinopril after long-term treatment in hypertensive diabetic rats
Wienen, Wolfgang, Richard, Serge, Champeroux, Pascal, Audeval-Gerard, Chantal
Published in Journal of the renin-angiotensin-aldosterone system (01.03.2001)
Published in Journal of the renin-angiotensin-aldosterone system (01.03.2001)
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BIBP 3226, the first selective neuropeptide Y1 receptor antagonist: A review of its pharmacological properties
Doods, Henri N., Wieland, Heike A., Engel, Wolfhard, Eberlein, Wolfgang, Willim, Klaus-Dieter, Entzeroth, Michael, Wienen, Wolfgang, Rudolf, Klaus
Published in Regulatory peptides (27.08.1996)
Published in Regulatory peptides (27.08.1996)
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Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions
Böhm, M, Lee, M, Kreutz, R, Kim, S, Schinke, M, Djavidani, B, Wagner, J, Kaling, M, Wienen, W, Bader, M
Published in Journal of hypertension (01.08.1995)
Published in Journal of hypertension (01.08.1995)
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Effects of AT1 receptor blockade on blood pressure and the renin-angiotensin system in spontaneously hypertensive rats of the stroke prone strain
Wagner, J, Drab, M, Bohlender, J, Amann, K, Wienen, W, Ganten, D
Published in Clinical and experimental hypertension (1993) (01.01.1998)
Published in Clinical and experimental hypertension (1993) (01.01.1998)
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The discovery of dabigatran etexilate
van Ryn, Joanne, Goss, Ashley, Hauel, Norbert, Wienen, Wolfgang, Priepke, Henning, Nar, Herbert, Clemens, Andreas
Published in Frontiers in pharmacology (01.01.2013)
Published in Frontiers in pharmacology (01.01.2013)
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A Review on Telmisartan: A Novel, Long‐Acting Angiotensin II‐Receptor Antagonist
Wienen, Wolfgang, Entzeroth, Michael, Meel, Jacobus C. A., Stangier, Joachim, Busch, Ulrich, Ebner, Thomas, Schmid, Jochen, Lehmann, Horst, Matzek, Kandace, Kempthorne‐Rawson, Joan, Gladigau, Volker, Hauel, Norbert H.
Published in Cardiovascular drug reviews (01.06.2000)
Published in Cardiovascular drug reviews (01.06.2000)
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Antithrombotic and anticoagulant effects of the direct thrombin inhibitor dabigatran, and its oral prodrug, dabigatran etexilate, in a rabbit model of venous thrombosis
WIENEN, W., STASSEN, J.‐M., PRIEPKE, H., RIES, U. J., HAUEL, N.
Published in Journal of thrombosis and haemostasis (01.06.2007)
Published in Journal of thrombosis and haemostasis (01.06.2007)
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