SECOND-GENERATION LEUKOTRIENE-B-4 RECEPTOR ANTAGONISTS RELATED TO SC-41930 - HETEROCYCLIC REPLACEMENT OF THE METHYL KETONE PHARMACOPHORE
PENNING, TD, DJURIC, SW, MIYASHIRO, JM, YU, S, SNYDER, JP, SPANGLER, D, ANGLIN, CP, FRETLAND, DJ, KACHUR, JF, KEITH, RH, TSAI, BS, VILLANIPRICE, D, WALSH, RE, WIDOMSKI, DL
Published in Journal of medicinal chemistry (17.03.1995)
Published in Journal of medicinal chemistry (17.03.1995)
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Specific inhibitors of inducible nitric oxide synthase: efficacy in a rodent model of sepsis
Fretland, D J, Widomski, D L, Anglin, C P, Moore, W, Jerome, G, Kornmeier, C, Connor, J, Branson, L, Wyatt, P, Manning, P, Toth, M, Webber, R K, Hansen, D, Hallinan, E A, Hagen, T, Bergmanis, A, Pitzele, B, Currie, M G
Published in Inflammation research (01.12.1999)
Published in Inflammation research (01.12.1999)
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Synthesis and pharmacological activity of SC-53228, a leukotriene B4 receptor antagonist with high intrinsic potency and selectivity
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Published in Bioorganic & medicinal chemistry letters (24.03.1994)
Published in Bioorganic & medicinal chemistry letters (24.03.1994)
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Interleukin 8 and mast cell-generated tumor necrosis factor-alpha in neutrophil recruitment
Zhang, Y, Ramos, B F, Jakschik, B, Baganoff, M P, Deppeler, C L, Meyer, D M, Widomski, D L, Fretland, D J, Bolanowski, M A
Published in Inflammation (01.02.1995)
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Identification and characterization of rhesus macaque interleukin-8
Minnerly, J C, Baganoff, M P, Deppeler, C L, Keller, B T, Rapp, S R, Widomski, D L, Fretland, D J, Bolanowski, M A
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Mucosal protective activity of prostaglandin analogs in rodent colonic inflammation
Fretland, D J, Widomski, D L, Anglin, C P, Walsh, R E, Levin, S, Gasiecki, A F, Collins, P W
Published in Inflammation (01.12.1992)
Published in Inflammation (01.12.1992)
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Leukotriene B4-induced granulocyte trafficking in guinea pig dermis. Effect of second-generation leukotriene B4 receptor antagonists, SC-50605 and SC-51146
Fretland, D J, Widomski, D L, Anglin, C P, Penning, T D, Yu, S, Djuric, S W
Published in Inflammation (01.06.1993)
Published in Inflammation (01.06.1993)
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Inflammation of guinea pig dermis. Effects of leukotriene B4 receptor antagonist, SC-41930
Fretland, D J, Widomski, D L, Zemaitis, J M, Walsh, R E, Levin, S, Djuric, S W, Shone, R L, Tsai, B S, Gaginella, T S
Published in Inflammation (01.12.1990)
Published in Inflammation (01.12.1990)
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Effect of a leukotriene B4 receptor antagonist on leukotriene B4-induced neutrophil chemotaxis in cavine dermis
Fretland, D J, Widomski, D L, Zemaitis, J M, Djurić, S W, Shone, R L
Published in Inflammation (01.10.1989)
Published in Inflammation (01.10.1989)
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12(R)-Hydroxyeicosatetraenoic acid is a neutrophil chemoattractant in the cavine, lapine, murine and canine dermis
Fretland, D.J., Widomski, D.L., Zemaitis, J.M., Tsai, B.S., Djuric, S.W., Penning, T.D., Miyashiro, J.M., Bauer, R.F.
Published in Prostaglandins, leukotrienes and essential fatty acids (01.08.1989)
Published in Prostaglandins, leukotrienes and essential fatty acids (01.08.1989)
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SC-41930 inhibits neutrophil infiltration of the cavine dermis induced by 12(R)-hydroxyeicosatetraenoic acid
Fretland, D.J., Widomski, D.L., Shone, R.L., Penning, T.D., Miyashiro, J.M., Djuric, S.W.
Published in Prostaglandins, leukotrienes and essential fatty acids (01.12.1989)
Published in Prostaglandins, leukotrienes and essential fatty acids (01.12.1989)
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Effects of the prostaglandin analogue misoprostol on inflammatory mediator release by human monocytes
Widomski, D L, Walsh, R E, Baron, D A, Hidvegi, M I, Fretland, D J, Collins, P W, Gaginella, T S
Published in Agents and actions (01.09.1991)
Published in Agents and actions (01.09.1991)
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The effect of leukotriene-B4 receptor antagonist, SC-41930, on acetic acid-induced colonic inflammation
Fretland, D J, Levin, S, Tsai, B S, Djurić, S W, Widomski, D L, Zemaitis, J M, Shone, R L, Bauer, R F
Published in Agents and actions (01.06.1989)
Published in Agents and actions (01.06.1989)
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Inflammatory mediators in cotton-top tamarins (CTT) with acute and chronic colitis
Clapp, N K, Henke, M A, Hansard, R M, Walsh, R E, Widomski, D L, Anglin, C P, Fretland, D J, Gaginella, T S
Published in Agents and actions (01.09.1991)
Published in Agents and actions (01.09.1991)
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The design and synthesis of second generation leukotriene B4 (LTB4) receptor antagonists related to SC-41930
Penning, T D, Djuric, S W, Docter, S H, Yu, S S, Spangler, D, Anglin, C P, Fretland, D J, Kachur, J F, Keith, R H, Tsai, B S
Published in Agents and actions (01.01.1993)
Published in Agents and actions (01.01.1993)
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