Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells
Chatterjee, Bithi, Smed-Sörensen, Anna, Cohn, Lillian, Chalouni, Cécile, Vandlen, Richard, Lee, Byoung-Chul, Widger, Jenifer, Keler, Tibor, Delamarre, Lélia, Mellman, Ira
Published in Blood (06.09.2012)
Published in Blood (06.09.2012)
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Journal Article
CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy
Wasiuk, Anna, Testa, James, Weidlick, Jeff, Sisson, Crystal, Vitale, Laura, Widger, Jenifer, Crocker, Andrea, Thomas, Lawrence J, Goldstein, Joel, Marsh, Henry C, Keler, Tibor, He, Li-Zhen
Published in The Journal of immunology (1950) (15.12.2017)
Published in The Journal of immunology (1950) (15.12.2017)
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Journal Article
Conditioning treatment with CD27 Ab enhances expansion and antitumor activity of adoptively transferred T cells in mice
Wasiuk, Anna, Weidlick, Jeff, Sisson, Crystal, Widger, Jenifer, Crocker, Andrea, Vitale, Laura, Marsh, Henry C., Keler, Tibor, He, Li-Zhen
Published in Cancer Immunology, Immunotherapy (01.01.2022)
Published in Cancer Immunology, Immunotherapy (01.01.2022)
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Journal Article
Development of a Novel Antibody-Drug Conjugate for the Potential Treatment of Ovarian, Lung, and Renal Cell Carcinoma Expressing TIM-1
Thomas, Lawrence J, Vitale, Laura, O'Neill, Thomas, Dolnick, Ree Y, Wallace, Paul K, Minderman, Hans, Gergel, Lauren E, Forsberg, Eric M, Boyer, James M, Storey, James R, Pilsmaker, Catherine D, Hammond, Russell A, Widger, Jenifer, Sundarapandiyan, Karuna, Crocker, Andrea, Marsh, Jr, Henry C, Keler, Tibor
Published in Molecular cancer therapeutics (01.12.2016)
Published in Molecular cancer therapeutics (01.12.2016)
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Journal Article
CDX-585, a Bispecific Antibody with Dual Targeting of ILT4 and PD-1 Checkpoint Pathways
Murphy, Michael B., Vitale, Laura, Xia, Shukai, Peng, Zeyu, O’Neill, Thomas, Lillquist, Jay, Wasiuk, Anna, Weidlick, Jeff, Widger, Jenifer, Mills-Chen, Laura, Crocker, Andrea, Patterson, Colleen, Boyer, James, Baronas, April R., Chen, Mingjiu, Davis, Hugh M., Ma, Mark, Goldstein, Joel, Thomas, Lawrence J., Alvarado, Diego, Marsh, Henry C., Keler, Tibor
Published in Immuno (01.09.2023)
Published in Immuno (01.09.2023)
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Journal Article
550 An Axl-targeting monoclonal antibody that inhibits Axl activity and potently stimulates the innate immune response
Alvarado, Diego, Vitale, Laura, Murphy, Mike, O’Neill, Thomas, Natoli, Edward, Lillquist, Jay, Crew, Linda, Wasiuk, Anna, Weidlick, Jeffrey, Sisson, Crystal, Widger, Jenifer, Mills-Chen, Laura, Crocker, Andrea, Patterson, Colleen, Boyer, James, Forsberg, Eric, Baronas, April, Mathieu, Taylor, Fields, Amelia, Hammond, Russell, He, Li-Zhen, Goldstein, Joel, Thomas, Lawrence, March, Henry, Keler, Tibor
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Dual targeting of mast cells and TSLP with a bispecific antibody
Alvarado, Diego, Vitale, Laura, Murphy, Michael B, Wasiuk, Anna, Widger, Jenifer, Crocker, Andrea, Patterson, Colleen, Mills-Chen, Laura, O’Neill, Thomas, Baronas, April R, McManus, Kelly M, Boyer, James M, Montanari, Noe Rico, Lillquist, Jay, Malenchek, Linda, Weidlick, Jeff, Goldstein, Joel, Thomas, Lawrence J, Marsh, Henry C, Keler, Tibor
Published in The Journal of immunology (1950) (01.05.2023)
Published in The Journal of immunology (1950) (01.05.2023)
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Journal Article
Abstract 1865: Simultaneous de-repression of innate and adaptive immune responses through dual targeting of ILT4 and PD(L)-1 with bispecific antibodies
Vitale, Laura, Murphy, Mike, Weidlick, Jeff, Wasiuk, Anna, O'Neill, Thomas, Widger, Jenifer, Mills-Chen, Laura, Crocker, Andrea, Patterson, Colleen, Boyer, James, Crew, Linda, Natoli, Edward J., Lillquist, Jay S., Goldstein, Joel, Thomas, Lawrence J., Marsh, Henry C., Alvarado, Diego, Keler, Tibor
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Development of CDX-527: a bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy
Vitale, Laura A., He, Li-Zhen, Thomas, Lawrence J., Wasiuk, Anna, O’Neill, Thomas, Widger, Jenifer, Crocker, Andrea, Mills-Chen, Laura, Forsberg, Eric, Weidlick, Jeffrey, Patterson, Colleen, Hammond, Russell A., Boyer, James, Sisson, Crystal, Alvarado, Diego, Goldstein, Joel, Marsh, Henry C., Keler, Tibor
Published in Cancer Immunology, Immunotherapy (01.10.2020)
Published in Cancer Immunology, Immunotherapy (01.10.2020)
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Journal Article
Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy
Vitale, Laura A., Thomas, Lawrence J., He, Li-Zhen, O’Neill, Thomas, Widger, Jenifer, Crocker, Andrea, Sundarapandiyan, Karuna, Storey, James R., Forsberg, Eric M., Weidlick, Jeffrey, Baronas, April R., Gergel, Lauren E., Boyer, James M., Sisson, Crystal, Goldstein, Joel, Marsh, Henry C., Keler, Tibor
Published in Cancer Immunology, Immunotherapy (01.02.2019)
Published in Cancer Immunology, Immunotherapy (01.02.2019)
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Journal Article
Abstract 3664: CDX-1402, a dendritic cell targeted fusion protein designed to elicit immunity to mesothelin and HER2 expressing tumors
He, Li-Zhen, Widger, Jenifer, Testa, James, Mills-Chen, Laura, Zhao, Biwei, Weidlick, Jeff, Sisson, Crystal, Wasiuk, Anna, Vitale, Laura, Goldstein, Joel, Marsh, Henry, Keler, Tibor, Ramakrishna, Venky
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 5624: Development of novel bispecific immune modulating antibodies
Vitale, Laura A., Thomas, Lawrence J., He, Li-Zhen, O'Neill, Thomas, Widger, Jenifer, Crocker, Andrea, Testa, James, Sundarapandiyan, Karuna, Forsberg, Eric, Boyer, James, Storey, James, Goldstein, Joel, Marsh, Henry C., Keler, Tibor
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 2392: CDX-527: A novel bispecific immune-modulating antibody targeting CD27 and PD-L1
Vitale, Laura A., Thomas, Lawrence J., O'Neill, Thomas, Widger, Jenifer, Mills-Chen, Laura, Crocker, Andrea, Patterson, Colleen, Wasiuk, Anna, Forsberg, Eric, Boyer, James, Sisson, Crystal, Weidlick, Jeffrey, Renn-Bingham, Shannon, Papayannopoulos, Ioannis, Hammond, Russ, Goldstein, Joel, Marsh, Henry C., Keler, Tibor, He, Li-Zhen
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 1555: Monoclonal antibodies targeting the TAM family of receptor tyrosine kinases
Alvarado, Diego, Vitale, Laura, Murphy, Mike, O'Neill, Thomas, Proffitt, Andrew, Lillquist, Jay, Ligon, Gwenda, Patel, Komal, Wasiuk, Anna, Weidlick, Jeff, Widger, Jenifer, Mills-Chen, Laura, Crocker, Andrea, Patterson, Colleen, Hammond, Russell A., He, Li-Zhen, Goldstein, Joel, Thomas, Lawrence J., Marsh, Henry C., Keler, Tibor, Gedrich, Richard
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
CDX-1140, a Novel Agonist CD40 Antibody with Potent Anti-Lymphoma Activity
He, Li-Zhen, Testa, James, Anna, Wasiuk, Jeffery, Weidlick, Sisson, Crystal, Vitale, Laura A., O'Neill, Thomas, Crocker, Andrea, Widger, Jenifer, Goldstein, Joel, Marsh Jr, Henry C., Keler, Tibor
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Abstract 4866: Development and characterization of novel CD40 antibody agonists for cancer immunotherapy
Vitale, Laura A., O’Neill, Thomas, Widger, Jenifer, Crocker, Andrea, He, Li-Zhen, Weidlick, Jeffrey, Sundarapandiyan, Karuna, Storey, James, Thomas, Lawrence, Goldstein, Joel, Marsh, Henry C., Keler, Tibor
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract B194: Identification and characterization of monoclonal antibodies targeting the Tyro3, Axl and MerTK (TAM) family of receptor tyrosine kinases
Alvarado, Diego, Vitale, Laura, Murphy, Michael, O'Neill, Thomas, Proffitt, Andrew, Lillquist, Jay, Ligon, Gwenda, Polson, Craig, Storey, James R., Widger, Jenifer, Mills-Chen, Laura, Sundarapandiyan, Karuna, Crocker, Andrea, Patterson, Colleen, Zhao, Biwei, Hammond, Russell A., He, Li-Zhen, Ramakrishna, Venky, Goldstein, Joel, Thomas, Lawrence, Marsh, Henry C., Keler, Tibor, Gedrich, Richard
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Journal Article
Abstract 2963: CDX-585, a novel bispecific antibody targeting PD-1 and ILT4
Thomas, Lawrence J., Vitale, Laura A., Murphy, Michael, Xia, Collin, Peng, Zeyu, Ejas, Asma, Patel, Montu, Boyer, James, Baronas, April R., O'Neill, Thomas, Widger, Jenifer, Mills-Chen, Laura, Crocker, Andrea, Ma, Mark, Chen, Mingjiu, Davis, Hugh M., Hammond, Russ A., Taglienti, Cherie, Yellin, Michael, Goldstein, Joel, Alvarado, Diego, Marsh, Henry C., Keler, Tibor
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 3519: Appropriate crosslinking is required for co-stimulatory activity of human CD27 antibody in a transgenic mouse model
He, Li-Zhen, Prostak, Naseem, Crocker, Andrea, Weidlick, Jeffery, Widger, Jenifer, Sisson, Crystal, Vitale, Laura, Glennie, Martin J., Keler, Tibor
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
인간 CD40에 결합하는 효능성 항체 및 이의 용도
KELER TIBOR, CROCKER ANDREA, HE LIZHEN, THOMAS LAWRENCE J, VITALE LAURA A, O'NEILL TOM, SUNDARAPANDIYAN KARUNA, WIDGER JENIFER, GOLDSTEIN JOEL
Year of Publication 14.12.2018
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Year of Publication 14.12.2018
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