The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif
Williams, Leslie K, Zhang, Xiaohua, Caner, Sami, Tysoe, Christina, Nguyen, Nham T, Wicki, Jacqueline, Williams, David E, Coleman, John, McNeill, John H, Yuen, Violet, Andersen, Raymond J, Withers, Stephen G, Brayer, Gary D
Published in Nature chemical biology (01.09.2015)
Published in Nature chemical biology (01.09.2015)
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Journal Article
Multi-parametric MRI at 14T for muscular dystrophy mice treated with AAV vector-mediated gene therapy
Park, Joshua, Wicki, Jacqueline, Knoblaugh, Sue E, Chamberlain, Jeffrey S, Lee, Donghoon
Published in PloS one (09.04.2015)
Published in PloS one (09.04.2015)
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Journal Article
Efficacy and muscle safety assessment of fukutin-related protein gene therapy
Benasutti, Halli, Maricelli, Joseph W., Seto, Jane, Hall, John, Halbert, Christine, Wicki, Jacqueline, Huesgen, Lydia, Purvis, Nicholas, Regnier, Michael, Lin, David C., Rodgers, Buel D., Chamberlain, Jeffrey S.
Published in Molecular therapy. Methods & clinical development (14.09.2023)
Published in Molecular therapy. Methods & clinical development (14.09.2023)
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Journal Article
Potent Human α‑Amylase Inhibition by the β‑Defensin-like Protein Helianthamide
Tysoe, Christina, Williams, Leslie K, Keyzers, Robert, Nguyen, Nham T, Tarling, Chris, Wicki, Jacqueline, Goddard-Borger, Ethan D, Aguda, Adeleke H, Perry, Suzanne, Foster, Leonard J, Andersen, Raymond J, Brayer, Gary D, Withers, Stephen G
Published in ACS central science (23.03.2016)
Published in ACS central science (23.03.2016)
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Journal Article
Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors
Schitter, Georg, Scheucher, Elisabeth, Steiner, Andreas J, Stütz, Arnold E, Thonhofer, Martin, Tarling, Chris A, Withers, Stephen G, Wicki, Jacqueline, Fantur, Katrin, Paschke, Eduard, Mahuran, Don J, Rigat, Brigitte A, Tropak, Michael, Wrodnigg, Tanja M
Published in Beilstein journal of organic chemistry (01.03.2010)
Published in Beilstein journal of organic chemistry (01.03.2010)
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Journal Article
A New, Simple, High-Affinity Glycosidase Inhibitor: Analysis of Binding through X-ray Crystallography, Mutagenesis, and Kinetic Analysis
Williams, Spencer J, Notenboom, Valerie, Wicki, Jacqueline, Rose, David R, Withers, Stephen G
Published in Journal of the American Chemical Society (03.05.2000)
Published in Journal of the American Chemical Society (03.05.2000)
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Journal Article
Transition-State Mimicry by Glycosidase Inhibitors: A Critical Kinetic Analysis
Wicki, Jacqueline, Williams, Spencer J, Withers, Stephen G
Published in Journal of the American Chemical Society (18.04.2007)
Published in Journal of the American Chemical Society (18.04.2007)
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Journal Article
Development of a Clinical AAV-Based Vector Encoding a Microdystrophin Transgene for the Treatment of Duchenne Muscular Dystrophy
Wicki, Jacqueline, Banks, Glen B, Ng, Rainer, Allen, James, Finn, Eric E, Nguyen, Quynh V, Hauschka, Stephen D, Odom, Guy L, Chamberlain, Jeffrey S
Published in Molecular therapy (01.09.2013)
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Published in Molecular therapy (01.09.2013)
Journal Article
Circular Permutation of Bacillus circulans Xylanase: A Kinetic and Structural Study
Reitinger, Stephan, Yu, Ying, Wicki, Jacqueline, Ludwiczek, Martin, D’Angelo, Igor, Baturin, Simon, Okon, Mark, Strynadka, Natalie C. J, Lutz, Stefan, Withers, Stephen G, McIntosh, Lawrence P
Published in Biochemistry (Easton) (23.03.2010)
Published in Biochemistry (Easton) (23.03.2010)
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Journal Article
1-Deoxy-D-galactonojirimycins with dansyl capped N-substituents as beta-galactosidase inhibitors and potential probes for G(M1) gangliosidosis affected cell lines
Froehlich, Richard F. G., Furneaux, Richard H., Mahuran, Don J., Saf, Robert, Stuetz, Arnold E., Tropak, Michael B., Wicki, Jacqueline, Withers, Stephen G., Wrodnigg, Tanja M.
Published in Carbohydrate research (06.09.2011)
Published in Carbohydrate research (06.09.2011)
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Journal Article
A fluorescent probe for GM1 gangliosidosis related β-galactosidase: N-(Dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino- d-galactitol
Fröhlich, Richard F.G., Fantur, Katrin, Furneaux, Richard H., Paschke, Eduard, Stütz, Arnold E., Wicki, Jacqueline, Withers, Stephen G., Wrodnigg, Tanja M.
Published in Bioorganic & medicinal chemistry letters (15.11.2011)
Published in Bioorganic & medicinal chemistry letters (15.11.2011)
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Journal Article
1-Deoxy-d-galactonojirimycins with dansyl capped N-substituents as β-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines
Fröhlich, Richard F.G., Furneaux, Richard H., Mahuran, Don J., Saf, Robert, Stütz, Arnold E., Tropak, Michael B., Wicki, Jacqueline, Withers, Stephen G., Wrodnigg, Tanja M.
Published in Carbohydrate research (06.09.2011)
Published in Carbohydrate research (06.09.2011)
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Journal Article
A fluorescent probe for GM1 gangliosidosis related I super(2)-galactosidase: N-(Dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-d-ga l actitol
Fr&, ouml, hlich, Richard FG, Fantur, Katrin, Furneaux, Richard H, Paschke, Eduard, Stuetz, Arnold E, Wicki, Jacqueline, Withers, Stephen G, Wrodnigg, Tanja M
Published in Bioorganic & medicinal chemistry letters (15.11.2011)
Published in Bioorganic & medicinal chemistry letters (15.11.2011)
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Journal Article
Probing Electrostatic Interactions along the Reaction Pathway of a Glycoside Hydrolase: Histidine Characterization by NMR Spectroscopy
Schubert, Mario, Poon, David K. Y, Wicki, Jacqueline, Tarling, Chris A, Kwan, Emily M, Nielsen, Jens E, Withers, Stephen G, McIntosh, Lawrence P
Published in Biochemistry (Easton) (26.06.2007)
Published in Biochemistry (Easton) (26.06.2007)
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Journal Article
A fluorescent probe for GM1 gangliosidosis related β-galactosidase: N-(Dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-n-galactitol
FRÖHLICH, Richard F. G, FANTUR, Katrin, FURNEAUX, Richard H, PASCHKE, Eduard, STÜTZ, Arnold E, WICKI, Jacqueline, WITHERS, Stephen G, WRODNIGG, Tanja M
Published in Bioorganic & medicinal chemistry letters (2011)
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Published in Bioorganic & medicinal chemistry letters (2011)
Journal Article
1-Deoxynojirimycins with dansyl capped N-substituents as probes for Morbus Gaucher affected cell lines
Fröhlich, Richard F.G., Furneaux, Richard H., Mahuran, Don J., Rigat, Brigitte A., Stütz, Arnold E., Tropak, Michael B., Wicki, Jacqueline, Withers, Stephen G., Wrodnigg, Tanja M.
Published in Carbohydrate research (02.07.2010)
Published in Carbohydrate research (02.07.2010)
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Journal Article
Animal Models of Muscular Dystrophy
Ng, Rainer, Banks, Glen B., Hall, John K., Muir, Lindsey A., Ramos, Julian N., Wicki, Jacqueline, Odom, Guy L., Konieczny, Patryk, Seto, Jane, Chamberlain, Joel R., Chamberlain, Jeffrey S.
Published in Animal Models of Molecular Pathology (01.01.2012)
Published in Animal Models of Molecular Pathology (01.01.2012)
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