Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis
Tagliabracci, Vincent S, Engel, James L, Wiley, Sandra E, Xiao, Junyu, Gonzalez, David J, Nidumanda Appaiah, Hitesh, Koller, Antonius, Nizet, Victor, White, Kenneth E, Dixon, Jack E
Published in Proceedings of the National Academy of Sciences - PNAS (15.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (15.04.2014)
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Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo
Rhee, Yumie, Bivi, Nicoletta, Farrow, Emily, Lezcano, Virginia, Plotkin, Lilian I, White, Kenneth E, Bellido, Teresita
Published in Bone (New York, N.Y.) (01.10.2011)
Published in Bone (New York, N.Y.) (01.10.2011)
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Osteocytic FGF23 and Its Kidney Function
Agoro, Rafiou, Ni, Pu, Noonan, Megan L, White, Kenneth E
Published in Frontiers in endocrinology (Lausanne) (28.08.2020)
Published in Frontiers in endocrinology (Lausanne) (28.08.2020)
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Initial FGF23-Mediated Signaling Occurs in the Distal Convoluted Tubule
FARROW, Emily G, DAVIS, Siobhan I, SUMMERS, Lelia J, WHITE, Kenneth E
Published in Journal of the American Society of Nephrology (01.05.2009)
Published in Journal of the American Society of Nephrology (01.05.2009)
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Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice
Farrow, Emily G, Yu, Xijie, Summers, Lelia J, Davis, Siobhan I, Fleet, James C, Allen, Matthew R, Robling, Alexander G, Stayrook, Keith R, Jideonwo, Victoria, Magers, Martin J, Garringer, Holly J, Vidal, Ruben, Chan, Rebecca J, Goodwin, Charles B, Hui, Siu L, Peacock, Munro, White, Kenneth E
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2011)
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Osteocyte regulation of phosphate homeostasis and bone mineralization underlies the pathophysiology of the heritable disorders of rickets and osteomalacia
Feng, Jian Q, Clinkenbeard, Erica L, Yuan, Baozhi, White, Kenneth E, Drezner, Marc K
Published in Bone (New York, N.Y.) (01.06.2013)
Published in Bone (New York, N.Y.) (01.06.2013)
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Chronic Hyperphosphatemia and Vascular Calcification Are Reduced by Stable Delivery of Soluble Klotho
Hum, Julia M, O'Bryan, Linda M, Tatiparthi, Arun K, Cass, Taryn A, Clinkenbeard, Erica L, Cramer, Martin S, Bhaskaran, Manoj, Johnson, Robert L, Wilson, Jonathan M, Smith, Rosamund C, White, Kenneth E
Published in Journal of the American Society of Nephrology (01.04.2017)
Published in Journal of the American Society of Nephrology (01.04.2017)
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Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia
Clinkenbeard, Erica L, Cass, Taryn A, Ni, Pu, Hum, Julia M, Bellido, Teresita, Allen, Matthew R, White, Kenneth E
Published in Journal of bone and mineral research (01.06.2016)
Published in Journal of bone and mineral research (01.06.2016)
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Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism
Ward, Leanne M, Quarles, L Darryl, Feng, Jian Q, Liu, Shiguang, Lu, Yongbo, Xie, Yixia, Yuan, Baozhi, Yu, Xijie, Rauch, Frank, Davis, Siobhan I, Zhang, Shubin, Rios, Hector, Drezner, Marc K, Bonewald, Lynda F, White, Kenneth E
Published in Nature genetics (01.11.2006)
Published in Nature genetics (01.11.2006)
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Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow
Clinkenbeard, Erica L, Hanudel, Mark R, Stayrook, Keith R, Appaiah, Hitesh Nidumanda, Farrow, Emily G, Cass, Taryn A, Summers, Lelia J, Ip, Colin S, Hum, Julia M, Thomas, Joseph C, Ivan, Mircea, Richine, Briana M, Chan, Rebecca J, Clemens, Thomas L, Schipani, Ernestina, Sabbagh, Yves, Xu, Linlin, Srour, Edward F, Alvarez, Marta B, Kacena, Melissa A, Salusky, Isidro B, Ganz, Tomas, Nemeth, Elizabeta, White, Kenneth E
Published in Haematologica (Roma) (01.11.2017)
Published in Haematologica (Roma) (01.11.2017)
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Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes
Sakamoto, Eijiro, Kitase, Yukiko, Fitt, Alexander J., Zhu, Zewu, Awad, Kamal, Brotto, Marco, White, Kenneth E., Welc, Steven S., Bergwitz, Clemens, Bonewald, Lynda F.
Published in Cell reports (Cambridge) (23.07.2024)
Published in Cell reports (Cambridge) (23.07.2024)
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Neonatal Iron Deficiency Causes Abnormal Phosphate Metabolism by Elevating FGF23 in Normal and ADHR Mice
Clinkenbeard, Erica L, Farrow, Emily G, Summers, Lelia J, Cass, Taryn A, Roberts, Jessica L, Bayt, Christine A, Lahm, Tim, Albrecht, Marjorie, Allen, Matthew R, Peacock, Munro, White, Kenneth E
Published in Journal of bone and mineral research (01.02.2014)
Published in Journal of bone and mineral research (01.02.2014)
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Age and sex effects on FGF23-mediated response to mild phosphate challenge
Tippen, Samantha P., Noonan, Megan L., Ni, Pu, Metzger, Corinne E., Swallow, Elizabeth A., Sacks, Spencer A., Chen, Neal X., Thompson, William R., Prideaux, Matthew, Atkins, Gerald J., Moe, Sharon M., Allen, Matthew R., White, Kenneth E.
Published in Bone (New York, N.Y.) (01.05.2021)
Published in Bone (New York, N.Y.) (01.05.2021)
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Molecular Insights into the Klotho-Dependent, Endocrine Mode of Action of Fibroblast Growth Factor 19 Subfamily Members
Goetz, Regina, Beenken, Andrew, Ibrahimi, Omar A., Kalinina, Juliya, Olsen, Shaun K., Eliseenkova, Anna V., Xu, ChongFeng, Neubert, Thomas A., Zhang, Fuming, Linhardt, Robert J., Yu, Xijie, White, Kenneth E., Inagaki, Takeshi, Kliewer, Steven A., Yamamoto, Masaya, Kurosu, Hiroshi, Ogawa, Yasushi, Kuro-o, Makoto, Lanske, Beate, Razzaque, Mohammed S., Mohammadi, Moosa
Published in Molecular and Cellular Biology (01.05.2007)
Published in Molecular and Cellular Biology (01.05.2007)
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Generation of two multipotent mesenchymal progenitor cell lines capable of osteogenic, mature osteocyte, adipogenic, and chondrogenic differentiation
Prideaux, Matthew, Wright, Christian S., Noonan, Megan L., Yi, Xin, Clinkenbeard, Erica L., Mevel, Elsa, Wheeler, Jonathan A., Byers, Sharon, Wijenayaka, Asiri R., Gronthos, Stan, Sankar, Uma, White, Kenneth E., Atkins, Gerald J., Thompson, William R.
Published in Scientific reports (19.11.2021)
Published in Scientific reports (19.11.2021)
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Erythropoietin and a hypoxia‐inducible factor prolyl hydroxylase inhibitor (HIF‐PHDi) lowers FGF23 in a model of chronic kidney disease (CKD)
Noonan, Megan L., Clinkenbeard, Erica L., Ni, Pu, Swallow, Elizabeth A., Tippen, Samantha P., Agoro, Rafiou, Allen, Matthew R., White, Kenneth E.
Published in Physiological reports (01.06.2020)
Published in Physiological reports (01.06.2020)
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FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting
Riminucci, Mara, Collins, Michael T, Fedarko, Neal S, Cherman, Natasha, Corsi, Alessandro, White, Kenneth E, Waguespack, Steven, Gupta, Anurag, Hannon, Tamara, Econs, Michael J, Bianco, Paolo, Gehron Robey, Pamela
Published in The Journal of clinical investigation (01.09.2003)
Published in The Journal of clinical investigation (01.09.2003)
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