Correction to “Atropisomer Control in Macrocyclic Factor VIIa Inhibitors”
Glunz, Peter W, Mueller, Luciano, Cheney, Daniel L, Ladziata, Vladimir, Zou, Yan, Wurtz, Nicholas R, Wei, Anzhi, Wong, Pancras C, Wexler, Ruth R, Priestley, E. Scott
Published in Journal of medicinal chemistry (26.04.2018)
Published in Journal of medicinal chemistry (26.04.2018)
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Design and Synthesis of Isoxazoline Derivatives as Factor Xa Inhibitors. 2
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Published in Journal of medicinal chemistry (29.07.1999)
Published in Journal of medicinal chemistry (29.07.1999)
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Discovery of 3-Amino-4-Chlorophenyl P1 as a novel and potent benzamidine mimic via solid-phase synthesis of an isoxazoline library
Lam, Patrick Y.S., Adams, Jessica J., Clark, Charles G., Calhoun, W.Jason, Luettgen, Joseph M., Knabb, Robert M., Wexler, Ruth R.
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Published in Bioorganic & medicinal chemistry letters (19.05.2003)
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Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group
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Published in Bioorganic & medicinal chemistry (15.05.2016)
Published in Bioorganic & medicinal chemistry (15.05.2016)
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Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties
Pinto, Donald J.P., Smallheer, Joanne M., Corte, James R., Austin, Erin J.D., Wang, Cailan, Fang, Tianan, Smith, Leon M., Rossi, Karen A., Rendina, Alan R., Bozarth, Jeffrey M., Zhang, Ge, Wei, Anzhi, Ramamurthy, Vidhyashankar, Sheriff, Steven, Myers, Joseph E., Morin, Paul E., Luettgen, Joseph M., Seiffert, Dietmar A., Quan, Mimi L., Wexler, Ruth R.
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
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Corrigendum to “Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase” [Bioorg. Med. Chem. Lett. 29 (2019) 1918–1921]
Kim, Soong-Hoon, Johnson, James A., Jiang, Ji, Parkhurst, Brandon, Phillips, Monique, Pi, Zulan, Qiao, Jennifer X., Tora, George, Ye Chen, Alice, Liu, Eddie, Yin, Xiaohong, Yang, Richard, Zhao, Lei, Taylor, David S., Basso, Michael, Behnia, Kamelia, Onorato, Joelle, Chen, Xue-Qing, Abell, Lynn M., Lu, Hao, Locke, Gregory, Caporuscio, Christian, Adam, Leonard P., Gordon, David, Wexler, Ruth R., Finlay, Heather J.
Published in Bioorganic & medicinal chemistry letters (01.09.2019)
Published in Bioorganic & medicinal chemistry letters (01.09.2019)
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2-Aminothiazole based P2Y(1) antagonists as novel antiplatelet agents
Pi, Zulan, Sutton, James, Lloyd, John, Hua, Ji, Price, Laura, Wu, Qimin, Chang, Ming, Zheng, Joanna, Rehfuss, Robert, Huang, Christine S., Wexler, Ruth R., Lam, Patrick Y. S.
Published in Bioorganic & medicinal chemistry letters (15.07.2013)
Published in Bioorganic & medicinal chemistry letters (15.07.2013)
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Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors
Hu, Carol H., Wang, Tammy C., Qiao, Jennifer X., Haque, Lauren, Chen, Alice Y.A., Taylor, David S., Ying, Xiaohong, Onorato, Joelle M., Galella, Michael, Shen, Hong, Huang, Christine S., Toussaint, Nathalie, Li, Yi-Xin, Abell, Lynn, Adam, Leonard P., Gordon, David, Wexler, Ruth R., Finlay, Heather J.
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
Published in Bioorganic & medicinal chemistry letters (15.12.2018)
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Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening
Cheney, Daniel L, Bozarth, Jeffrey M, Metzler, William J, Morin, Paul E, Mueller, Luciano, Newitt, John A, Nirschl, Alexandra H, Rendina, Alan R, Tamura, James K, Wei, Anzhi, Wen, Xiao, Wurtz, Nicholas R, Seiffert, Dietmar A, Wexler, Ruth R, Priestley, E. Scott
Published in Journal of medicinal chemistry (26.03.2015)
Published in Journal of medicinal chemistry (26.03.2015)
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Novel phenylalanine derived diamides as Factor XIa inhibitors
Smith, Leon M., Orwat, Michael J., Hu, Zilun, Han, Wei, Wang, Cailan, Rossi, Karen A., Gilligan, Paul J., Pabbisetty, Kumar B., Osuna, Honey, Corte, James R., Rendina, Alan R., Luettgen, Joseph M., Wong, Pancras C., Narayanan, Ranga, Harper, Timothy W., Bozarth, Jeffrey M., Crain, Earl J., Wei, Anzhi, Ramamurthy, Vidhyashankar, Morin, Paul E., Xin, Baomin, Zheng, Joanna, Seiffert, Dietmar A., Quan, Mimi L., Lam, Patrick Y.S., Wexler, Ruth R., Pinto, Donald J.P.
Published in Bioorganic & medicinal chemistry letters (15.01.2016)
Published in Bioorganic & medicinal chemistry letters (15.01.2016)
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New azole antagonists with high affinity for the P2Y(1) receptor
Ruel, Rejean, L'Heureux, Alexandre, Thibeault, Carl, Daris, Jean-Paul, Martel, Alain, Price, Laura A., Wu, Qimin, Hua, Ji, Wexler, Ruth R., Rehfuss, Robert, Lam, Patrick Y. S.
Published in Bioorganic & medicinal chemistry letters (15.06.2013)
Published in Bioorganic & medicinal chemistry letters (15.06.2013)
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Neutral macrocyclic factor VIIa inhibitors
Wurtz, Nicholas R., Parkhurst, Brandon L., DeLucca, Indawati, Glunz, Peter W., Jiang, Wen, Zhang, Xiaojun, Cheney, Daniel L., Bozarth, Jeffrey M., Rendina, Alan R., Wei, Anzhi, Harper, Tim, Luettgen, Joseph M., Wu, Yiming, Wong, Pancras C., Seiffert, Dietmar A., Wexler, Ruth R., Priestley, E. Scott
Published in Bioorganic & medicinal chemistry letters (15.06.2017)
Published in Bioorganic & medicinal chemistry letters (15.06.2017)
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Synthesis and P1′ SAR exploration of potent macrocyclic tissue factor-factor VIIa inhibitors
Ladziata, Vladimir (Uladzimir), Glunz, Peter W., Zou, Yan, Zhang, Xiaojun, Jiang, Wen, Jacutin-Porte, Swanee, Cheney, Daniel L., Wei, Anzhi, Luettgen, Joseph M., Harper, Timothy M., Wong, Pancras C., Seiffert, Dietmar, Wexler, Ruth R., Priestley, E. Scott
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
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Pyridine and pyridinone-based factor XIa inhibitors
Corte, James R., Fang, Tianan, Hangeland, Jon J., Friends, Todd J., Rendina, Alan R., Luettgen, Joseph M., Bozarth, Jeffrey M., Barbera, Frank A., Rossi, Karen A., Wei, Anzhi, Ramamurthy, Vidhyashankar, Morin, Paul E., Seiffert, Dietmar A., Wexler, Ruth R., Quan, Mimi L.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Design and Synthesis of Isoxazoline Derivatives as Factor Xa Inhibitors. 1
Quan, Mimi L, Liauw, Ann Y, Ellis, Christopher D, Pruitt, James R, Carini, David J, Bostrom, Lori L, Huang, Peggy P, Harrison, Kimberly, Knabb, Robert M, Thoolen, Martin J, Wong, Pancras C, Wexler, Ruth R
Published in Journal of medicinal chemistry (29.07.1999)
Published in Journal of medicinal chemistry (29.07.1999)
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Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors
Glunz, Peter W., Cheng, Xuhong, Cheney, Daniel L., Weigelt, Carolyn A., Wei, Anzhi, Luettgen, Joseph M., Wong, Pancras C., Wexler, Ruth R., Priestley, E. Scott
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
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Triazolopyrimidines identified as reversible myeloperoxidase inhibitors
Duclos, Franck, Abell, Lynn M., Harden, David G., Pike, Kristen, Nowak, Kimberly, Locke, Gregory A., Duke, Gerald J., Liu, Xiaoqin, Fernando, Gayani, Shaw, Scott A., Vokits, Benjamin P., Wurtz, Nicholas R., Viet, Andrew, Valente, Meriah N., Stachura, Sylwia, Sleph, Paul, Khan, Javed A., Gao, Ji, Dongre, Ashok R., Zhao, Lei, Wexler, Ruth R., Gordon, David A., Kick, Ellen K.
Published in MedChemComm (01.11.2017)
Published in MedChemComm (01.11.2017)
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Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase
Johnson, James A, Tora, George, Pi, Zulan, Phillips, Monique, Yin, Xiaohong, Yang, Richard, Zhao, Lei, Chen, Alice Y, Taylor, David S, Basso, Michael, Rose, Anne, Behnia, Kamelia, Onorato, Joelle, Chen, Xue-Qing, Abell, Lynn M, Lu, Hao, Locke, Gregory, Caporuscio, Christian, Galella, Michael, Adam, Leonard P, Gordon, David, Wexler, Ruth R, Finlay, Heather J
Published in ACS medicinal chemistry letters (13.12.2018)
Published in ACS medicinal chemistry letters (13.12.2018)
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Discovery of Highly Potent Liver X Receptor β Agonists
Kick, Ellen K, Busch, Brett B, Martin, Richard, Stevens, William C, Bollu, Venkataiah, Xie, Yinong, Boren, Brant C, Nyman, Michael C, Nanao, Max H, Nguyen, Lam, Plonowski, Artur, Schulman, Ira G, Yan, Grace, Zhang, Huiping, Hou, Xiaoping, Valente, Meriah N, Narayanan, Rangaraj, Behnia, Kamelia, Rodrigues, A. David, Brock, Barry, Smalley, James, Cantor, Glenn H, Lupisella, John, Sleph, Paul, Grimm, Denise, Ostrowski, Jacek, Wexler, Ruth R, Kirchgessner, Todd, Mohan, Raju
Published in ACS medicinal chemistry letters (08.12.2016)
Published in ACS medicinal chemistry letters (08.12.2016)
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Discovery of Potent Isoxazoline Glycoprotein IIb/IIIa Receptor Antagonists
Wityak, John, Sielecki, Thais M, Pinto, Donald J, Emmett, George, Sze, Jean Y, Liu, Jie, Tobin, A. Ewa, Wang, Shuaige, Jiang, Biao, Ma, Philip, Mousa, Shaker A, Wexler, Ruth R, Olson, Richard E
Published in Journal of medicinal chemistry (03.01.1997)
Published in Journal of medicinal chemistry (03.01.1997)
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