Milvexian, an orally bioavailable, small‐molecule, reversible, direct inhibitor of factor XIa: In vitro studies and in vivo evaluation in experimental thrombosis in rabbits
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Published in Journal of thrombosis and haemostasis (01.02.2022)
Published in Journal of thrombosis and haemostasis (01.02.2022)
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Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy
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Published in Journal of medicinal chemistry (10.02.2022)
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Factor XIa Inhibitors as New Anticoagulants
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Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Published in Science translational medicine (04.01.2017)
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Published in Bioorganic & medicinal chemistry letters (15.05.2023)
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Factor Xa Inhibitors: Next-Generation Antithrombotic Agents
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Published in Journal of medicinal chemistry (09.09.2010)
Published in Journal of medicinal chemistry (09.09.2010)
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Published in Journal of medicinal chemistry (23.12.2021)
Published in Journal of medicinal chemistry (23.12.2021)
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Published in Journal of medicinal chemistry (14.12.2017)
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Published in Bioorganic & medicinal chemistry letters (15.10.2021)
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Published in Bioorganic & medicinal chemistry letters (01.10.2022)
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Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO)
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Johnson, James A, Kim, Soong-Hoon, Jiang, Ji, Phillips, Monique, Schumacher, William A, Bostwick, Jeffrey S, Gargalovic, Peter S, Onorato, Joelle M, Luk, Chiuwa E, Generaux, Claudia, He, Yan, Chen, Xue-Qing, Xu, Carrie, Galella, Michael A, Wang, Tao, Gordon, David A, Wexler, Ruth R, Finlay, Heather J
Published in Journal of medicinal chemistry (25.03.2021)
Published in Journal of medicinal chemistry (25.03.2021)
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