Dapagliflozin, a Selective SGLT2 Inhibitor, Improves Glucose Homeostasis in Normal and Diabetic Rats
SONGPING HAN, HAGAN, Deborah L, TAYLOR, Joseph R, LI XIN, WEI MENG, BILLER, Scott A, WETTERAU, John R, WASHBURN, William N, WHALEY, Jean M
Published in Diabetes (New York, N.Y.) (01.06.2008)
Published in Diabetes (New York, N.Y.) (01.06.2008)
Get full text
Journal Article
Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models
Wang, Xiaojun, Yu, Xiaohong, Gavardinas, Kostas, Dey, Asim, Zhang, Hong Y, Porter, Gina, Porras, Leah, Yu, Lan, Guo, Haihong, Reidy, Charles A, Haas, Joseph V, Xu, Yanping, Kowala, Mark C, Jadhav, Prabhakar K, Wetterau, John R
Published in PloS one (26.01.2024)
Published in PloS one (26.01.2024)
Get full text
Journal Article
Estimating the distribution of a novel clinical biomarker (FGF-23) in the US population using findings from a regional research registry
Johnston, Joseph A, Nelson, David R, Zhang, Limin, Curtis, Sarah E, Voelker, James R, Wetterau, John R
Published in PloS one (27.06.2019)
Published in PloS one (27.06.2019)
Get full text
Journal Article
Effects of pharmacological inhibition of the sodium‐dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models
Wang, Xiaojun, Xu, Yanping, Yu, Xiaohong, Dey, Asim, Zhang, Hong Y., Zink, Charity M., Wodka, Derek, Porter, Gina, Matter, William F., Porras, Leah, Reidy, Charles A., Peterson, Jeffrey A., Mattioni, Brian E., Haas, Joseph V., Kowala, Mark C., Wetterau, John R.
Published in Pharmacology research & perspectives (01.04.2022)
Published in Pharmacology research & perspectives (01.04.2022)
Get full text
Journal Article
Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes
Meng, Wei, Ellsworth, Bruce A, Nirschl, Alexandra A, McCann, Peggy J, Patel, Manorama, Girotra, Ravindar N, Wu, Gang, Sher, Philip M, Morrison, Eamonn P, Biller, Scott A, Zahler, Robert, Deshpande, Prashant P, Pullockaran, Annie, Hagan, Deborah L, Morgan, Nathan, Taylor, Joseph R, Obermeier, Mary T, Humphreys, William G, Khanna, Ashish, Discenza, Lorell, Robertson, James G, Wang, Aiying, Han, Songping, Wetterau, John R, Janovitz, Evan B, Flint, Oliver P, Whaley, Jean M, Washburn, William N
Published in Journal of medicinal chemistry (13.03.2008)
Published in Journal of medicinal chemistry (13.03.2008)
Get full text
Journal Article
Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells
Jamil, H, Chu, C H, Dickson, Jr, J K, Chen, Y, Yan, M, Biller, S A, Gregg, R E, Wetterau, J R, Gordon, D A
Published in Journal of lipid research (01.07.1998)
Published in Journal of lipid research (01.07.1998)
Get full text
Journal Article
Protein disulfide isomerase appears necessary to maintain the catalytically active structure of the microsomal triglyceride transfer protein
Wetterau, John R, Combs, Kelly A, McLean, Larry R, Spinner, Sara N, Aggerbeck, Lawrence P
Published in Biochemistry (Easton) (08.10.1991)
Published in Biochemistry (Easton) (08.10.1991)
Get full text
Journal Article
Design and Synthesis of N-[(4-Methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with Efficacious Glucose and Lipid-Lowering Activities
Devasthale, Pratik V, Chen, Sean, Jeon, Yoon, Qu, Fucheng, Shao, Chunning, Wang, Wei, Zhang, Hao, Cap, Michael, Farrelly, Dennis, Golla, Rajasree, Grover, Gary, Harrity, Thomas, Ma, Zhengping, Moore, Lisa, Ren, Jimmy, Seethala, Ramakrishna, Cheng, Lin, Sleph, Paul, Sun, Wei, Tieman, Aaron, Wetterau, John R, Doweyko, Arthur, Chandrasena, Gamini, Chang, Shu Y, Humphreys, W. Griffith, Sasseville, Vito G, Biller, Scott A, Ryono, Denis E, Selan, Fred, Hariharan, Narayanan, Cheng, Peter T. W
Published in Journal of medicinal chemistry (24.03.2005)
Published in Journal of medicinal chemistry (24.03.2005)
Get full text
Journal Article
Structural properties of the microsomal triglyceride-transfer protein complex
Wetterau, John R, Aggerbeck, Lawrence P, Laplaud, P. Michel, McLean, Larry R
Published in Biochemistry (Easton) (07.05.1991)
Published in Biochemistry (Easton) (07.05.1991)
Get full text
Journal Article
Absence of Microsomal Triglyceride Transfer Protein in Individuals with Abetalipoproteinemia
Wetterau, John R., Aggerbeck, Lawrence P., Bouma, Marie-Elisabeth, Eisenberg, Claude, Munck, Anne, Hermier, Michel, Schmitz, Jacques, Gay, Gerard, Rader, Daniel J., Gregg, Richard E.
Published in Science (American Association for the Advancement of Science) (06.11.1992)
Published in Science (American Association for the Advancement of Science) (06.11.1992)
Get full text
Journal Article
Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia
Sharp, Daru, Blinderman, Laura, Combs, Kelly A, Kienzle, Bernadette, Ricci, Beverly, Wager-Smith, Karen, Gil, Cleris M, Turck, Christoph W, Boumas, Marie-Elizabeth, Rader, Daniel J, Aggerbeck, Lawrence P, Gregg, Richard E, Gordon, David A, Wetterau, John R
Published in Nature (London) (02.09.1993)
Published in Nature (London) (02.09.1993)
Get full text
Journal Article
Microsomal triglyceride transfer protein
Wetterau, John R, Lin, Marie C.M, Jamil, Haris
Published in Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism (01.04.1997)
Published in Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism (01.04.1997)
Get full text
Book Review
Journal Article
Total deficiency of plasma cholesteryl ester transfer protein in subjects homozygous and heterozygous for the intron 14 splicing defect
Yamashita, Shizuya, Hui, David Y, Sprecher, Dennis L, Matsuzawa, Yuji, Sakai, Naohiko, Tarui, Seiichiro, Kaplan, David, Wetterau, John R, Harmony, Judith AK
Published in Biochemical and biophysical research communications (16.08.1990)
Published in Biochemical and biophysical research communications (16.08.1990)
Get full text
Journal Article
A Novel Series of Highly Potent Benzimidazole-Based Microsomal Triglyceride Transfer Protein Inhibitors
Robl, Jeffrey A, Sulsky, Richard, Sun, Chong-Qing, Simpkins, Ligaya M, Wang, Tammy, Dickson, John K, Chen, Ying, Magnin, David R, Taunk, Prakash, Slusarchyk, William A, Biller, Scott A, Lan, Shih-Jung, Connolly, Fergal, Kunselman, Lori K, Sabrah, Talal, Jamil, Haris, Gordon, David, Harrity, Thomas W, Wetterau, John R
Published in Journal of medicinal chemistry (15.03.2001)
Published in Journal of medicinal chemistry (15.03.2001)
Get full text
Journal Article
Anderson's Disease: Exclusion of Apolipoprotein and Intracellular Lipid Transport Genes
Dannoura, A Hayssam, Berriot-Varoqueaux, Nathalie, Amati, Patricia, Abadie, Veronique, Verthier, Nicole, Schmitz, Jacques, Wetterau, John R, Samson-Bouma, Marie-Elisabeth, Aggerbeck, Lawrence P
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.1999)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.1999)
Get full text
Journal Article
The Amino Terminus of Apolipoprotein B Is Necessary but Not Sufficient for Microsomal Triglyceride Transfer Protein Responsiveness (∗)
Gretch, Daniel G., Sturley, Stephen L., Wang, Lin, Lipton, Beth A., Dunning, Alison, Grunwald, Kurt A.A., Wetterau, John R., Yao, Zemin, Talmud, Philippa, Attie, Alan D.
Published in The Journal of biological chemistry (12.04.1996)
Published in The Journal of biological chemistry (12.04.1996)
Get full text
Journal Article
Estimating the distribution of a novel clinical biomarker
Johnston, Joseph A, Nelson, David R, Zhang, Limin, Curtis, Sarah E, Voelker, James R, Wetterau, John R
Published in PloS one (27.06.2019)
Published in PloS one (27.06.2019)
Get full text
Journal Article
A 30-Amino Acid Truncation of the Microsomal Triglyceride Transfer Protein Large Subunit Disrupts Its Interaction with Protein Disulfide-isomerase and Causes Abetalipoproteinemia
Ricci, Beverly, Sharp, Daru, O'Rourke, Edward, Kienzle, Bernadette, Blinderman, Laura, Gordon, David, Smith-Monroy, Connie, Robinson, Gordon, Gregg, Richard E., Rader, Daniel J., Wetterau, John R.
Published in The Journal of biological chemistry (16.06.1995)
Published in The Journal of biological chemistry (16.06.1995)
Get full text
Journal Article