Search Results - "WESTON, ALEXIS" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer

The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer

by Soldi, Raffaella, Ghosh Halder, Tithi, Weston, Alexis, Thode, Trason, Drenner, Kevin, Lewis, Rhonda, Kaadige, Mohan R, Srivastava, Shreyesi, Daniel Ampanattu, Sherin, Rodriguez Del Villar, Ryan, Lang, Jessica, Vankayalapati, Hariprasad, Weissman, Bernard, Trent, Jeffrey M, Hendricks, William P D, Sharma, Sunil
Published in PloS one (10.07.2020)

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Journal Article

Histone Deacetylase Inhibition Has Targeted Clinical Benefit in ARID1A -Mutated Advanced Urothelial Carcinoma

Histone Deacetylase Inhibition Has Targeted Clinical Benefit in ARID1A -Mutated Advanced Urothelial Carcinoma

by Gupta, Sumati, Albertson, Daniel J, Parnell, Timothy J, Butterfield, Andrew, Weston, Alexis, Pappas, Lisa M, Dalley, Brian, O'Shea, John M, Lowrance, William T, Cairns, Bradley R, Schiffman, Joshua D, Sharma, Sunil
Published in Molecular cancer therapeutics (01.01.2019)

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Journal Article

897-G SR-8541A, a small molecule inhibitor of ENPP1, enhances the effect of immune checkpoint inhibitors in a colorectal cancer model

897-G SR-8541A, a small molecule inhibitor of ENPP1, enhances the effect of immune checkpoint inhibitors in a colorectal cancer model

by Weston, Alexis, Thode, Trason, Ng, Serina, Ghosh-Halder, Tithi, Gutowsky, Katelyn, Durbin, Brian, Soldi, Raffaella, Shah, Monil, Northrup, Jonathan, Kasibhatla, Srinivas, Kaadige, Mohan, Sharma, Sunil
Published in Journal for immunotherapy of cancer (01.11.2023)

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Journal Article

Abstract 1175: Identification of novel combination therapies with the LSD1 inhibitor SP-2577 (Seclidemstat) in Ewing's Sarcoma using a complete druggable CRISPR library approach

Abstract 1175: Identification of novel combination therapies with the LSD1 inhibitor SP-2577 (Seclidemstat) in Ewing's Sarcoma using a complete druggable CRISPR library approach

by Sampson, Samuel, Thode, Trason, Kaadige, Mohan, Weston, Alexis, Ng, Serina, Drenner, Kevin, Soldi, Raffaella, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (01.07.2021)

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Journal Article

Abstract 3869: The reversible LSD1 inhibitor SP-2509 promotes anti-tumor immunity in small cell carcinoma of the ovary-hypercalcemic type (SCCOHT)

Abstract 3869: The reversible LSD1 inhibitor SP-2509 promotes anti-tumor immunity in small cell carcinoma of the ovary-hypercalcemic type (SCCOHT)

by Soldi, Raffaella, Weston, Alexis, Thode, Trason, Lewis, Rhonda, Kaadige, Mohan, Vankayalapati, Hariprasad, Hendricks, William, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (01.07.2019)

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Journal Article

Abstract LB-107: Targeting CDK7-dependent transcriptional addiction with novel, orally available small molecule inhibitor shows efficacy in pancreatic cancer models

Abstract LB-107: Targeting CDK7-dependent transcriptional addiction with novel, orally available small molecule inhibitor shows efficacy in pancreatic cancer models

by Thode, Trason, Li, Zhaoliang, Weston, Alexis, Soldi, Raffaella, Kaadige, Mohan Rao, Vankayalapti, Hariprasad, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (01.07.2019)

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Journal Article

Abstract LB-118: SR8541A is a potent inhibitor of ENPP1 and exhibits dendritic cell mediated antitumor activity

Abstract LB-118: SR8541A is a potent inhibitor of ENPP1 and exhibits dendritic cell mediated antitumor activity

by WESTON, ALEXIS S., Thode, Trason G., Rodriguez del Villar, Ryan, Dana, Srikanta, Kasibhatla, Srinivas, Kaadige, Mohan R., Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (15.08.2020)

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Journal Article

Abstract 1254: Preclinical studies with TGN-1062, a selective and reversible small molecule inhibitor of CDK7

Abstract 1254: Preclinical studies with TGN-1062, a selective and reversible small molecule inhibitor of CDK7

by Rodriguez del Villar, Ryan L., Thode, Trason G., Weston, Alexis, Ng, Serina, Soldi, Raffaella, Kaadige, Mohan, Kasibhatla, Srinivas, Chung, Vincent, Chao, Joseph, Von Hoff, Daniel D., Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (01.07.2021)

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Journal Article

Abstract 3068: Everolimus mediated Radioprotection on surrounding healthy tissue in glioblastoma microbrain models

Abstract 3068: Everolimus mediated Radioprotection on surrounding healthy tissue in glioblastoma microbrain models

by Halder, Tithi Ghosh, del Villar, Ryan Rodriguez, Lacombe, Jerome, Drenner, Kevin, Ng, Serina, Thode, Trason, Weston, Alexis, Kaadige, Mohan, Soldi, Raffaella, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (01.07.2021)

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Journal Article

Abstract 1932: Discovery of ENPP1 inhibitors as agonists of STING pathway

Abstract 1932: Discovery of ENPP1 inhibitors as agonists of STING pathway

by Sharma, Sunil, Weston, Alexis, Thode, Trason, Gomez, Eric, Kaadige, Mohan, Vankayalapti, Hariprasad
Published in Cancer research (Chicago, Ill.) (01.07.2018)

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Journal Article

Abstract 3077: Preclinical studies of SR-8314, a highly selective ENPP1 inhibitor and an activator of STING pathway

Abstract 3077: Preclinical studies of SR-8314, a highly selective ENPP1 inhibitor and an activator of STING pathway

by Weston, Alexis, Thode, Trason, Munoz, Ruben, Daniel, Sherin, Soldi, Raffaella, Kaadige, Mohan, Han, Haiyong, Vankayalapti, Hariprasad, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (01.07.2019)

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Journal Article

Abstract 5221: Development of TGN-1076, a selective and reversible small molecule inhibitor of CDK7

Abstract 5221: Development of TGN-1076, a selective and reversible small molecule inhibitor of CDK7

by Thode, Trason, Li, Zhaoliang, Weston, Alexis, Dana, Srikanta, Ampanattu, Sherin Daniel, Soldi, Raffaella, Kaadige, Mohan Rao, Vankayalapti, Hariprasad, Chung, Vincent, Chao, Joseph, Von Hoff, Daniel D, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (15.08.2020)

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Journal Article

Abstract 6681: Inhibition of LSD1 using the reversible inhibitor SP2577 promotes Interferon dependent anti-tumor response in adrenocortical carcinoma

Abstract 6681: Inhibition of LSD1 using the reversible inhibitor SP2577 promotes Interferon dependent anti-tumor response in adrenocortical carcinoma

by Sharma, Sunil, Soldi, Raffaella, Weston, Alexis, Sampson, Samuel, Ampanattu, Sherin Daniel, Celinski, Scott, Han, Haiyong, Kaadige, Mohan, Berens, Michael, Trent, Jeffrey
Published in Cancer research (Chicago, Ill.) (15.08.2020)

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Journal Article

Abstract 96: Effect of LSD-1 inhibition on docetaxel resistance in prostate cancer cells

Abstract 96: Effect of LSD-1 inhibition on docetaxel resistance in prostate cancer cells

by Gupta, Sumati, Weston, Alexis, Bearrs, Jared, Soldi, Raffaella, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (01.08.2015)

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Journal Article

The Small Molecule BC-2059 Inhibits Wingless/Integrated (Wnt)-Dependent Gene Transcription in Cancer through Disruption of the Transducin β -Like 1- β -Catenin Protein Complex

The Small Molecule BC-2059 Inhibits Wingless/Integrated (Wnt)-Dependent Gene Transcription in Cancer through Disruption of the Transducin β -Like 1- β -Catenin Protein Complex

by Soldi, Raffaella, Halder, Tithi Ghosh, Sampson, Samuel, Vankayalapati, Hariprasad, Weston, Alexis, Thode, Trason, Bhalla, Kapil N, Ng, Serina, Rodriguez Del Villar, Ryan, Drenner, Kevin, Kaadige, Mohan R, Horrigan, Stephen K, Batra, Surinder K, Salgia, Ravi, Sharma, Sunil
Published in The Journal of pharmacology and experimental therapeutics (01.08.2021)

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Journal Article

$Abstract C91: Reversible lysine specific demethylase-1 inhibition is synergistic with docetaxel in castrate refractory prostate cancer$

Abstract C91: Reversible lysine specific demethylase-1 inhibition is synergistic with docetaxel in castrate refractory prostate cancer

by Gupta, Sumati, Weston, Alexis, Bearss, Jared, Sharma, Sunil
Published in Molecular cancer therapeutics (01.12.2015)

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Journal Article

Abstract CT161: First-in-human study of ENPP1 inhibitor, SR-8541A, for the treatment of solid tumors

Abstract CT161: First-in-human study of ENPP1 inhibitor, SR-8541A, for the treatment of solid tumors

by Weston, Alexis S., Thode, Trason, Shah, Monil, Seiz, Amanda, Northrup, Jonathan, Kasibhatla, Srinivas, Kaadige, Mohan, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (05.04.2024)

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Journal Article

GFI1B Splice Variants Differentially Regulate Transcription and Megakaryocyte/Erythrocyte Fate in Hematopoiesis

GFI1B Splice Variants Differentially Regulate Transcription and Megakaryocyte/Erythrocyte Fate in Hematopoiesis

by McClellan, David, Singer, Jason, Velinder, Matthew, Bareyan, Diana, Casey, Mattie, Lucente, Helena, Weston, Alexis, Sharma, Sunil, Engel, Michael
Published in Blood (08.12.2017)

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Journal Article

ENPP1 억제제로서의 이미다졸 화합물

ENPP1 억제제로서의 이미다졸 화합물

by KAADIGE MOHAN, KASIBHATLA SRINIVAS RAO, SHARMA SUNIL, THODE TRASON, WESTON ALEXIS
Year of Publication 14.08.2023

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Patent

ENPP1 및 CDNP의 억제제로서의 포스포네이트

ENPP1 및 CDNP의 억제제로서의 포스포네이트

by KAADIGE MOHAN, KASIBHATLA SRINIVAS RAO, SHARMA SUNIL, THODE TRASON, WESTON ALEXIS
Year of Publication 11.08.2023

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Patent