RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics
Best, Myron G., Sol, Nik, Kooi, Irsan, Tannous, Jihane, Westerman, Bart A., Rustenburg, François, Schellen, Pepijn, Verschueren, Heleen, Post, Edward, Koster, Jan, Ylstra, Bauke, Ameziane, Najim, Dorsman, Josephine, Smit, Egbert F., Verheul, Henk M., Noske, David P., Reijneveld, Jaap C., Nilsson, R. Jonas A., Tannous, Bakhos A., Wesseling, Pieter, Wurdinger, Thomas
Published in Cancer cell (09.11.2015)
Published in Cancer cell (09.11.2015)
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KLIFS: an overhaul after the first 5 years of supporting kinase research
Kanev, Georgi K, de Graaf, Chris, Westerman, Bart A, de Esch, Iwan J P, Kooistra, Albert J
Published in Nucleic acids research (08.01.2021)
Published in Nucleic acids research (08.01.2021)
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Neuroblastoma is composed of two super-enhancer-associated differentiation states
van Groningen, Tim, Koster, Jan, Valentijn, Linda J, Zwijnenburg, Danny A, Akogul, Nurdan, Hasselt, Nancy E, Broekmans, Marloes, Haneveld, Franciska, Nowakowska, Natalia E, Bras, Johannes, van Noesel, Carel J M, Jongejan, Aldo, van Kampen, Antoine H, Koster, Linda, Baas, Frank, van Dijk-Kerkhoven, Lianne, Huizer-Smit, Margriet, Lecca, Maria C, Chan, Alvin, Lakeman, Arjan, Molenaar, Piet, Volckmann, Richard, Westerhout, Ellen M, Hamdi, Mohamed, van Sluis, Peter G, Ebus, Marli E, Molenaar, Jan J, Tytgat, Godelieve A, Westerman, Bart A, van Nes, Johan, Versteeg, Rogier
Published in Nature genetics (01.08.2017)
Published in Nature genetics (01.08.2017)
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Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL
Blombery, Piers, Lew, Thomas E., Dengler, Michael A., Thompson, Ella R., Lin, Victor S., Chen, Xiangting, Nguyen, Tamia, Panigrahi, Ashish, Handunnetti, Sasanka M., Carney, Dennis A., Westerman, David A., Tam, Constantine S., Adams, Jerry M., Wei, Andrew H., Huang, David C.S., Seymour, John F., Roberts, Andrew W., Anderson, Mary Ann
Published in Blood (24.02.2022)
Published in Blood (24.02.2022)
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Computational flow cytometry provides accurate assessment of measurable residual disease in chronic lymphocytic leukaemia
Nguyen, Phillip C., Nguyen, Vuong, Baldwin, Kylie, Kankanige, Yamuna, Blombery, Piers, Came, Neil, Westerman, David A.
Published in British journal of haematology (01.08.2023)
Published in British journal of haematology (01.08.2023)
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The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures
Narayan, Ravi S, Fedrigo, Carlos A, Brands, Eelke, Dik, Rogier, Stalpers, Lukas J A, Baumert, Brigitta G, Slotman, Ben J, Westerman, Bart A, Peters, Godefridus J, Sminia, Peter
Published in BMC cancer (21.03.2017)
Published in BMC cancer (21.03.2017)
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Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks
Kanev, Georgi K, Zhang, Yaran, Kooistra, Albert J, Bender, Andreas, Leurs, Rob, Bailey, David, Würdinger, Thomas, de Graaf, Chris, de Esch, Iwan J. P, Westerman, Bart A
Published in PLoS computational biology (05.09.2023)
Published in PLoS computational biology (05.09.2023)
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Journal Article
p120-catenin-dependent collective brain infiltration by glioma cell networks
Gritsenko, Pavlo G., Atlasy, Nader, Dieteren, Cindy E. J., Navis, Anna C., Venhuizen, Jan-Hendrik, Veelken, Cornelia, Schubert, Dirk, Acker-Palmer, Amparo, Westerman, Bart A., Wurdinger, Thomas, Leenders, William, Wesseling, Pieter, Stunnenberg, Hendrik G., Friedl, Peter
Published in Nature cell biology (01.01.2020)
Published in Nature cell biology (01.01.2020)
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Oncogenic composite mutations can be predicted by co‐mutations and their chromosomal location
Küçükosmanoglu, Asli, Borden, Carolien L., Boer, Lisanne E. A., Verhaak, Roel, Noske, David, Wurdinger, Tom, Radonic, Teodora, Westerman, Bart A.
Published in Molecular oncology (01.10.2024)
Published in Molecular oncology (01.10.2024)
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A multicentre retrospective comparison of central nervous system prophylaxis strategies among patients with high-risk diffuse large B-cell lymphoma
Cheah, C Y, Herbert, K E, O'Rourke, K, Kennedy, G A, George, A, Fedele, P L, Gilbertson, M, Tan, S Y, Ritchie, D S, Opat, S S, Prince, H M, Dickinson, M, Burbury, K, Wolf, M, Januszewicz, E H, Tam, C S, Westerman, D A, Carney, D A, Harrison, S J, Seymour, J F
Published in British journal of cancer (09.09.2014)
Published in British journal of cancer (09.09.2014)
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HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia
Eltzschig, Holger K, Abdulla, Parween, Hoffman, Edgar, Hamilton, Kathryn E, Daniels, Dionne, Schönfeld, Caroline, Löffler, Michaela, Reyes, German, Duszenko, Michael, Karhausen, Jorn, Robinson, Andreas, Westerman, Karen A, Coe, Imogen R, Colgan, Sean P
Published in The Journal of experimental medicine (05.12.2005)
Published in The Journal of experimental medicine (05.12.2005)
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ZNF423 Is Critically Required for Retinoic Acid-Induced Differentiation and Is a Marker of Neuroblastoma Outcome
Huang, Sidong, Laoukili, Jamila, Epping, Mirjam T., Koster, Jan, Hölzel, Michael, Westerman, Bart A., Nijkamp, Wouter, Hata, Akiko, Asgharzadeh, Shahab, Seeger, Robert C., Versteeg, Rogier, Beijersbergen, Roderick L., Bernards, René
Published in Cancer cell (07.04.2009)
Published in Cancer cell (07.04.2009)
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Radio-sensitizing effect of MEK inhibition in glioblastoma in vitro and in vivo
Houweling, M., Abdul, U. K., Brahm, C., Lagerweij, T., Heukelom, S., Koken, P. W., Honeywell, R., Wedekind, L. E., Peters, G. J., Verheul, H., Sminia, P., Noske, D., Wurdinger, T., Westerman, B. A.
Published in Journal of cancer research and clinical oncology (2023)
Published in Journal of cancer research and clinical oncology (2023)
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Journal Article
Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders
BLOMBERY, Piers A, WONG, Stephen Q, HEWITT, Chelsee A, DOBROVIC, Alexander, MAXWELL, Ellen L, JUNEJA, Surender, GRIGORIADIS, George, WESTERMAN, David A
Published in Haematologica (Roma) (01.05.2012)
Published in Haematologica (Roma) (01.05.2012)
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Cross-Tissue Transcriptomic Analysis of Human Secondary Lymphoid Organ-Residing ILC3s Reveals a Quiescent State in the Absence of Inflammation
Bar-Ephraim, Yotam E., Cornelissen, Ferry, Papazian, Natalie, Konijn, Tanja, Hoogenboezem, Remco M., Sanders, Mathijs A., Westerman, Bart A., Gönültas, Mehmet, Kwekkeboom, Jaap, Den Haan, Joke M.M., Reijmers, Rogier M., Mebius, Reina E., Cupedo, Tom
Published in Cell reports (Cambridge) (17.10.2017)
Published in Cell reports (Cambridge) (17.10.2017)
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Journal Article
Correction of Sickle Cell Disease in Transgenic Mouse Models by Gene Therapy
Pawliuk, Robert, Westerman, Karen A., Fabry, Mary E., Payen, Emmanuel, Tighe, Robert, Bouhassira, Eric E., Acharya, Seetharama A., Ellis, James, London, Irving M., Eaves, Connie J., Humphries, R. Keith, Beuzard, Yves, Nagel, Ronald L., Leboulch, Philippe
Published in Science (American Association for the Advancement of Science) (14.12.2001)
Published in Science (American Association for the Advancement of Science) (14.12.2001)
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Clinicopathological differences exist between CALR- and JAK2-mutated myeloproliferative neoplasms despite a similar molecular landscape: data from targeted next-generation sequencing in the diagnostic laboratory
Agarwal, Rishu, Blombery, Piers, McBean, Michelle, Jones, Kate, Fellowes, Andrew, Doig, Ken, Forsyth, Cecily, Westerman, David A.
Published in Annals of hematology (01.05.2017)
Published in Annals of hematology (01.05.2017)
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Therapy-related myelodysplastic syndrome and acute myeloid leukemia following fludarabine combination chemotherapy
Carney, D A, Westerman, D A, Tam, C S, Milner, A, Prince, H M, Kenealy, M, Wolf, M, Januszewicz, E H, Ritchie, D, Came, N, Seymour, J F
Published in Leukemia (01.12.2010)
Published in Leukemia (01.12.2010)
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