SGN-LIV1A: a novel antibody-drug conjugate targeting LIV-1 for the treatment of metastatic breast cancer
Sussman, Django, Smith, Leia M, Anderson, Martha E, Duniho, Steve, Hunter, Joshua H, Kostner, Heather, Miyamoto, Jamie B, Nesterova, Albina, Westendorf, Lori, Van Epps, Heather A, Whiting, Nancy, Benjamin, Dennis R
Published in Molecular cancer therapeutics (01.12.2014)
Published in Molecular cancer therapeutics (01.12.2014)
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Journal Article
Development of orally active inhibitors of protein and cellular fucosylation
Okeley, Nicole M., Alley, Stephen C., Anderson, Martha E., Boursalian, Tamar E., Burke, Patrick J., Emmerton, Kim M., Jeffrey, Scott C., Klussman, Kerry, Law, Che-Leung, Sussman, Django, Toki, Brian E., Westendorf, Lori, Zeng, Weiping, Zhang, Xinqun, Benjamin, Dennis R., Senter, Peter D.
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2013)
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Journal Article
SGN-CD48A: a Novel Humanized Anti-CD48 Antibody-Drug Conjugate for the Treatment of Multiple Myeloma
Lewis, Tim S., Olson, Devra, Gordon, Kristine, Sandall, Sharsti, Quick, Marsha, Finn, Margo, Westendorf, Lori, Linares, Germein, Leiske, Chris, Nesterova, Albina, Huang, Lanshan, Goswami, Maitrayee, Wang, Sa, Law, Che-Leung
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index
McDonagh, Charlotte F, Kim, Kristine M, Turcott, Eileen, Brown, Lindsay L, Westendorf, Lori, Feist, Tiffany, Sussman, Django, Stone, Ivan, Anderson, Martha, Miyamoto, Jamie, Lyon, Robert, Alley, Stephen C, Gerber, Hans-Peter, Carter, Paul J
Published in Molecular cancer therapeutics (01.09.2008)
Published in Molecular cancer therapeutics (01.09.2008)
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Journal Article
Anti-CD30 diabody-drug conjugates with potent antitumor activity
Kim, Kristine M, McDonagh, Charlotte F, Westendorf, Lori, Brown, Lindsay L, Sussman, Django, Feist, Tiffany, Lyon, Robert, Alley, Stephen C, Okeley, Nicole M, Zhang, Xinqun, Thompson, Melissa C, Stone, Ivan, Gerber, Hans-Peter, Carter, Paul J
Published in Molecular cancer therapeutics (01.08.2008)
Published in Molecular cancer therapeutics (01.08.2008)
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Journal Article
A major role for zygotic hunchback in patterning the Nasonia embryo
Pultz, Mary Anne, Westendorf, Lori, Gale, Samuel D, Hawkins, Kyle, Lynch, Jeremy, Pitt, Jason N, Reeves, Nick L, Yao, Jennifer C Y, Small, Stephen, Desplan, Claude, Leaf, David S
Published in Development (Cambridge) (01.08.2005)
Published in Development (Cambridge) (01.08.2005)
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Journal Article
SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML
Kung Sutherland, May S., Walter, Roland B., Jeffrey, Scott C., Burke, Patrick J., Yu, Changpu, Kostner, Heather, Stone, Ivan, Ryan, Maureen C., Sussman, Django, Lyon, Robert P., Zeng, Weiping, Harrington, Kimberly H., Klussman, Kerry, Westendorf, Lori, Meyer, David, Bernstein, Irwin D., Senter, Peter D., Benjamin, Dennis R., Drachman, Jonathan G., McEarchern, Julie A.
Published in Blood (22.08.2013)
Published in Blood (22.08.2013)
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Journal Article
Mouse Strains Influence Clearance and Efficacy of Antibody and Antibody-Drug Conjugate Via Fc-FcγR Interaction
Li, Fu, Ulrich, Michelle L, Shih, Vincent Feng-Sheng, Cochran, Julia H, Hunter, Joshua H, Westendorf, Lori, Neale, Jason, Benjamin, Dennis R
Published in Molecular cancer therapeutics (01.04.2019)
Published in Molecular cancer therapeutics (01.04.2019)
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Journal Article
Tumor-Associated Macrophages Can Contribute to Antitumor Activity through FcγR-Mediated Processing of Antibody-Drug Conjugates
Li, Fu, Ulrich, Michelle, Jonas, Mechthild, Stone, Ivan J, Linares, Germein, Zhang, Xinqun, Westendorf, Lori, Benjamin, Dennis R, Law, Che-Leung
Published in Molecular cancer therapeutics (01.07.2017)
Published in Molecular cancer therapeutics (01.07.2017)
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Journal Article
SGN-B6A: A New Vedotin Antibody–Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications
Lyon, Robert P., Jonas, Mechthild, Frantz, Christopher, Trueblood, Esther S., Yumul, Roma, Westendorf, Lori, Hale, Christopher J., Stilwell, Jackie L., Yeddula, Narayana, Snead, Katie M., Kumar, Vineet, Patilea-Vrana, Gabriela I., Klussman, Kerry, Ryan, Maureen C.
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Journal Article
Abstract 2906: SGN-B6A: A new MMAE ADC targeting integrin beta-6 in multiple carcinoma indications
Lyon, Robert P., Schmitt, Michael W., Jonas, Mechthild, Franz, Christopher E., Trueblood, Esther S., Yumul, Roma, Westendorf, Lori, Ryan, Maureen C.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
항-αvβ6 항체 및 항체-약물 접합체
RYAN MAUREEN, KOSTNER HEATHER JEAN, MEYER ERIC BRADLEY, WESTENDORF LORI
Year of Publication 05.08.2022
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Year of Publication 05.08.2022
Patent
SGN-CD228A Is an Investigational CD228-Directed Antibody-Drug Conjugate with Potent Antitumor Activity across a Wide Spectrum of Preclinical Solid Tumor Models
Mazahreh, Rebecca, Mason, Marsha L, Gosink, John J, Olson, Devra J, Thurman, Robert, Hale, Christopher, Westendorf, Lori, Pires, Thomas A, Leiske, Christopher I, Carlson, Markus, Nguyen, Liem T, Cochran, Julia H, Okeley, Nicole M, Yumul, Roma, Jin, Steven, Stone, Ivan J, Sahetya, Disha, Nesterova, Albina, Allred, Sean, Hensley, Kelly M, Hu, Rachael, Lawrence, Robert, Lewis, Timothy S, Sandall, Sharsti
Published in Molecular cancer therapeutics (03.04.2023)
Published in Molecular cancer therapeutics (03.04.2023)
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Journal Article
Abstract 3762: Superior T cell activity of a membrane-proximal binding antibody when targeting Glypican-3 with an antibody-coupled T-cell receptor (ACTR) armed T cell
Motz, Greg, Shin, John, Whiteman, Kathleen, Schultes, Birgit, Pai, Tapasya, Westendorf, Lori, Ettenberg, Seth, Biechele, Travis, Sussman, Django, Huet, Heather
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 3833: SEA-BCMA: A highly active enhanced antibody for multiple myeloma
Epps, Heather Van, Anderson, Martha, Yu, Changpu, Klussman, Kerry, Westendorf, Lori, Carosino, Chris, Manlove, Luke, Cochran, Julia, Neale, Jason, Benjamin, Dennis, Ryan, Maureen
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 2688: SGN-CD228A: A novel humanized anti-CD228 antibody-drug conjugate for the treatment of solid tumors
Sandall, Sharsti L., Mason, Marsha, Olson, Devra, Mazahreh, Rebecca, Pires, Tom, Sahetya, Disha, Westendorf, Lori, Leiske, Chris, Schimpf, Brian, Nguyen, Liem, Katepalli, Madhu, Trueblood, Esther, Hale, Christopher, Nesterova, Albina, Wall, Jason, Lewis, Timothy S.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 2082: Fc-FcR interaction impacts the clearance and antitumor activity of antibody-drug conjugates in NSG mice
Li, Fu, Ulrich, Michelle, Hunter, Joshua, Westendorf, Lori, Olson, Devra, Lee, Cassie Baker, Benjamin, Dennis, Law, Che-Leung
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 2082: Fc-FcγR interaction impacts the clearance and antitumor activity of antibody-drug conjugates in NSG mice
Li, Fu, Ulrich, Michelle, Hunter, Joshua, Westendorf, Lori, Olson, Devra, Lee, Cassie Baker, Benjamin, Dennis, Law, Che-Leung
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 1285: Tumor associated macrophages can process antibody-drug conjugates and contribute to antitumor activity in preclinical xenograft models
Li, Fu, Ulrich, Michelle, Jonas, Mechthild, Linares, Germein, Zhang, Xinqun, Westendorf, Lori, Benjamin, Dennis, Law, Che-Leung
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article