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Mezzadra, Riccardo, Sun, Chong, Jae, Lucas T., Gomez-Eerland, Raquel, de Vries, Evert, Wu, Wei, Logtenberg, Meike E. W., Slagter, Maarten, Rozeman, Elisa A., Hofland, Ingrid, Broeks, Annegien, Horlings, Hugo M., Wessels, Lodewyk F. A., Blank, Christian U., Xiao, Yanling, Heck, Albert J. R., Borst, Jannie, Brummelkamp, Thijn R., Schumacher, Ton N. M.
Published in Nature (London) (07.09.2017)
Published in Nature (London) (07.09.2017)
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Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial‐to‐mesenchymal transition
Roepman, Paul, Schlicker, Andreas, Tabernero, Josep, Majewski, Ian, Tian, Sun, Moreno, Victor, Snel, Mireille H, Chresta, Christine M, Rosenberg, Robert, Nitsche, Ulrich, Macarulla, Teresa, Capella, Gabriel, Salazar, Ramon, Orphanides, George, Wessels, Lodewyk FA, Bernards, Rene, Simon, Iris M
Published in International journal of cancer (01.02.2014)
Published in International journal of cancer (01.02.2014)
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Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours
Fernandes Neto, João M., Nadal, Ernest, Bosdriesz, Evert, Ooft, Salo N., Farre, Lourdes, McLean, Chelsea, Klarenbeek, Sjoerd, Jurgens, Anouk, Hagen, Hannes, Wang, Liqin, Felip, Enriqueta, Martinez-Marti, Alex, Vidal, August, Voest, Emile, Wessels, Lodewyk F. A., van Tellingen, Olaf, Villanueva, Alberto, Bernards, René
Published in Nature communications (22.06.2020)
Published in Nature communications (22.06.2020)
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Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency
Gisler, Santiago, Gonçalves, Joana P., Akhtar, Waseem, de Jong, Johann, Pindyurin, Alexey V., Wessels, Lodewyk F. A., van Lohuizen, Maarten
Published in Nature communications (08.04.2019)
Published in Nature communications (08.04.2019)
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ecpc: an R-package for generic co-data models for high-dimensional prediction
van Nee, Mirrelijn M, Wessels, Lodewyk F A, van de Wiel, Mark A
Published in BMC bioinformatics (26.04.2023)
Published in BMC bioinformatics (26.04.2023)
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Gene expression profiles from formalin fixed paraffin embedded breast cancer tissue are largely comparable to fresh frozen matched tissue
Mittempergher, Lorenza, de Ronde, Jorma J, Nieuwland, Marja, Kerkhoven, Ron M, Simon, Iris, Rutgers, Emiel J Th, Wessels, Lodewyk F A, Van't Veer, Laura J
Published in PloS one (11.02.2011)
Published in PloS one (11.02.2011)
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Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer
Annunziato, Stefano, de Ruiter, Julian R., Henneman, Linda, Brambillasca, Chiara S., Lutz, Catrin, Vaillant, François, Ferrante, Federica, Drenth, Anne Paulien, van der Burg, Eline, Siteur, Bjørn, van Gerwen, Bas, de Bruijn, Roebi, van Miltenburg, Martine H., Huijbers, Ivo J., van de Ven, Marieke, Visvader, Jane E., Lindeman, Geoffrey J., Wessels, Lodewyk F. A., Jonkers, Jos
Published in Nature communications (23.01.2019)
Published in Nature communications (23.01.2019)
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MicroRNA Sequence and Expression Analysis in Breast Tumors by Deep Sequencing
FARAZI, Thalia A, HORLINGS, Hugo M, KREIKE, Bas, SIE, Daoud, HOVESTADT, Volker, WESSELS, Lodewyk F. A, VAN DE VIJVER, Marc J, TUSCHL, Thomas, TEN HOEVE, Jelle J, MIHAILOVIC, Aleksandra, HALFWERK, Hans, MOROZOV, Pavel, BROWN, Miguel, HAFNER, Markus, REYAL, Fabien, VAN KOUWENHOVE, Marieke
Published in Cancer research (Chicago, Ill.) (01.07.2011)
Published in Cancer research (Chicago, Ill.) (01.07.2011)
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Spatial relationships in the urothelial and head and neck tumor microenvironment predict response to combination immune checkpoint inhibitors
Gil-Jimenez, Alberto, van Dijk, Nick, Vos, Joris L., Lubeck, Yoni, van Montfoort, Maurits L., Peters, Dennis, Hooijberg, Erik, Broeks, Annegien, Zuur, Charlotte L., van Rhijn, Bas W. G., Vis, Daniel J., van der Heijden, Michiel S., Wessels, Lodewyk F. A.
Published in Nature communications (21.03.2024)
Published in Nature communications (21.03.2024)
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Chromatin landscapes of retroviral and transposon integration profiles
de Jong, Johann, Akhtar, Waseem, Badhai, Jitendra, Rust, Alistair G, Rad, Roland, Hilkens, John, Berns, Anton, van Lohuizen, Maarten, Wessels, Lodewyk F A, de Ridder, Jeroen
Published in PLoS genetics (01.04.2014)
Published in PLoS genetics (01.04.2014)
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Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential
Kneppers, Jeroen, Severson, Tesa M., Siefert, Joseph C., Schol, Pieter, Joosten, Stacey E. P., Yu, Ivan Pak Lok, Huang, Chia-Chi Flora, Morova, Tunç, Altıntaş, Umut Berkay, Giambartolomei, Claudia, Seo, Ji-Heui, Baca, Sylvan C., Carneiro, Isa, Emberly, Eldon, Pasaniuc, Bogdan, Jerónimo, Carmen, Henrique, Rui, Freedman, Matthew L., Wessels, Lodewyk F. A., Lack, Nathan A., Bergman, Andries M., Zwart, Wilbert
Published in Nature communications (30.11.2022)
Published in Nature communications (30.11.2022)
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Fewer permutations, more accurate P-values
Knijnenburg, Theo A., Wessels, Lodewyk F. A., Reinders, Marcel J. T., Shmulevich, Ilya
Published in Bioinformatics (15.06.2009)
Published in Bioinformatics (15.06.2009)
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Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer
Liu, Xiaoling, Holstege, Henne, van der Gulden, Hanneke, Treur-Mulder, Marcelle, Zevenhoven, John, Velds, Arno, Kerkhoven, Ron M, van Vliet, Martin H, Wessels, Lodewyk F.A, Peterse, Johannes L, Berns, Anton, Jonkers, Jos
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2007)
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Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response
de Ronde, Jorma J, Hannemann, Juliane, Halfwerk, Hans, Mulder, Lennart, Straver, Marieke E, Vrancken Peeters, Marie-Jeanne T. F. D, Wesseling, Jelle, van de Vijver, Marc, Wessels, Lodewyk F. A, Rodenhuis, Sjoerd
Published in Breast cancer research and treatment (01.01.2010)
Published in Breast cancer research and treatment (01.01.2010)
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A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers
Šuštić, Tonći, van Wageningen, Sake, Bosdriesz, Evert, Reid, Robert J D, Dittmar, John, Lieftink, Cor, Beijersbergen, Roderick L, Wessels, Lodewyk F A, Rothstein, Rodney, Bernards, René
Published in Genome medicine (27.11.2018)
Published in Genome medicine (27.11.2018)
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Gene-Expression and Immunohistochemical Study of Specific T-Cell Subsets and Accessory Cell Types in the Transformation and Prognosis of Follicular Lymphoma
GLAS, Annuska M, KNOOPS, Laurent, KLUIN, Philip M, VAN 'T VEER, Laura J, DE JONG, Daphne, DELAHAYE, Leonie, KERSTEN, Marie José, KIBBELAAR, Robby E, WESSELS, Lodewyk A, VAN LAAR, Ryan, VAN KRIEKEN, J. Han J. M, BAARS, Joke W, RAEMAEKERS, John
Published in Journal of clinical oncology (01.02.2007)
Published in Journal of clinical oncology (01.02.2007)
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Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells
van der Stoop, Petra, Boutsma, Erwin A, Hulsman, Danielle, Noback, Sonja, Heimerikx, Mike, Kerkhoven, Ron M, Voncken, J Willem, Wessels, Lodewyk F A, van Lohuizen, Maarten
Published in PloS one (21.05.2008)
Published in PloS one (21.05.2008)
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Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines
Schlicker, Andreas, Beran, Garry, Chresta, Christine M, McWalter, Gael, Pritchard, Alison, Weston, Susie, Runswick, Sarah, Davenport, Sara, Heathcote, Kerry, Castro, Denis Alferez, Orphanides, George, French, Tim, Wessels, Lodewyk F A
Published in BMC medical genomics (31.12.2012)
Published in BMC medical genomics (31.12.2012)
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