Cleavage of Cohesin by the CD Clan Protease Separin Triggers Anaphase in Yeast
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Published in Cell (27.10.2000)
Published in Cell (27.10.2000)
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A novel orally available seleno-purine molecule suppresses triple-negative breast cancer cell proliferation and progression to metastasis by inducing cytostatic autophagy
Chang, Chia-Hao, Bijian, Krikor, Wernic, Dominik, Su, Jie, da Silva, Sabrina Daniela, Yu, Henry, Qiu, Dinghong, Asslan, Mariana, Alaoui-Jamali, Moulay A.
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Published in Autophagy (03.08.2019)
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Novel Aurora A and Protein Kinase C (α, β1, β2, and θ) Multitarget Inhibitors: Impact of Selenium Atoms on the Potency and Selectivity
Bijian, Krikor, Wernic, Dominik, Nivedha, Anita K, Su, Jie, Lim, Felicia Phei Lin, Miron, Caitlin E, Amzil, Hind, Moitessier, Nicolas, Alaoui-Jamali, Moulay A
Published in Journal of medicinal chemistry (24.02.2022)
Published in Journal of medicinal chemistry (24.02.2022)
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A prodrug strategy for the oral delivery of a poorly soluble HCV NS5B thumb pocket 1 polymerase inhibitor using self-emulsifying drug delivery systems (SEDDS)
Beaulieu, Pierre L., De Marte, Josie, Garneau, Michel, Luo, Laibin, Stammers, Timothy, Telang, Chitra, Wernic, Dominik, Kukolj, George, Duan, Jianmin
Published in Bioorganic & medicinal chemistry letters (15.01.2015)
Published in Bioorganic & medicinal chemistry letters (15.01.2015)
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Regulation of Human Separase by Securin Binding and Autocleavage
Waizenegger, Irene C., Giménez-Abián, Juan F., Wernic, Dominik, Peters, Jan-Michael
Published in Current biology (20.08.2002)
Published in Current biology (20.08.2002)
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Discovery of BI 207524, an Indole Diamide NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection
Beaulieu, Pierre L, Anderson, Paul C, Bethell, Richard, Bös, Michael, Bousquet, Yves, Brochu, Christian, Cordingley, Michael G, Fazal, Gulrez, Garneau, Michel, Gillard, James R, Kawai, Stephen, Marquis, Martin, McKercher, Ginette, Poupart, Marc-André, Stammers, Timothy, Thavonekham, Bounkham, Wernic, Dominik, Duan, Jianmin, Kukolj, George
Published in Journal of medicinal chemistry (11.12.2014)
Published in Journal of medicinal chemistry (11.12.2014)
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Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay
Stammers, Timothy A., Coulombe, René, Duplessis, Martin, Fazal, Gulrez, Gagnon, Alexandre, Garneau, Michel, Goulet, Sylvie, Jakalian, Araz, LaPlante, Steven, Rancourt, Jean, Thavonekham, Bounkham, Wernic, Dominik, Kukolj, George, Beaulieu, Pierre L.
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
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Aligning Potency and Pharmacokinetic Properties for Pyridine-Based NCINIs
Fader, Lee D, Bailey, Murray, Beaulieu, Eric, Bilodeau, François, Bonneau, Pierre, Bousquet, Yves, Carson, Rebekah J, Chabot, Catherine, Coulombe, René, Duan, Jianmin, Fenwick, Craig, Garneau, Michel, Halmos, Ted, Jakalian, Araz, James, Clint, Kawai, Stephen H, Landry, Serge, LaPlante, Steven R, Mason, Stephen W, Morin, Sebastien, Rioux, Nathalie, Simoneau, Bruno, Surprenant, Simon, Thavonekham, Bounkham, Thibeault, Carl, Trinh, Thao, Tsantrizos, Youla, Tsoung, Jennifer, Yoakim, Christiane, Wernic, Dominik
Published in ACS medicinal chemistry letters (11.08.2016)
Published in ACS medicinal chemistry letters (11.08.2016)
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Peptide-based inhibitors of the hepatitis C virus serine protease
Llinàs-Brunet, Montse, Bailey, Murray, Fazal, Gulrez, Goulet, Sylvie, Halmos, Ted, Laplante, Steven, Maurice, Roger, Poirier, Martin, Poupart, Marc-André, Thibeault, Diane, Wernic, Dominik, Lamarre, Daniel
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
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Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors
Llinàs-Brunet, Montse, Bailey, Murray, Fazal, Gulrez, Ghiro, Elise, Gorys, Vida, Goulet, Sylvie, Halmos, Ted, Maurice, Roger, Poirier, Martin, Poupart, Marc-André, Rancourt, Jean, Thibeault, Diane, Wernic, Dominik, Lamarre, Daniel
Published in Bioorganic & medicinal chemistry letters (16.10.2000)
Published in Bioorganic & medicinal chemistry letters (16.10.2000)
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Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease
Llinàs-Brunet, Montse, Bailey, Murray, Déziel, Robert, Fazal, Gulrez, Gorys, Vida, Goulet, Sylvie, Halmos, Ted, Maurice, Roger, Poirier, Martin, Poupart, Marc-André, Rancourt, Jean, Thibeault, Diane, Wernic, Dominik, Lamarre, Daniel
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
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Ligands for the tyrosine kinase p56(lck) SH2 domain: Discovery of potent dipeptide derivatives with monocharged, nonhydrolyzable phosphate replacements
Beaulieu, PL, Cameron, DR, Ferland, JM, Gauthier, J, Ghiro, E, Gillard, J, Gorys, Poirier, M, Rancourt, J, Wernic, D, Llinas-Brunet, M, Betageri, R, Cardozo, M, Hickey, ER, Ingraham, R, Jakes, S, Kabcenell, A, Kirrane, T, Lukas, S, Patel, U, Proudfoot, J, Sharma, R, Tong, L, Moss, N
Published in Journal of medicinal chemistry (20.05.1999)
Published in Journal of medicinal chemistry (20.05.1999)
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Practical, Stereoselective Synthesis of Palinavir, a Potent HIV Protease Inhibitor
Beaulieu, Pierre L, Lavallée, Pierre, Abraham, Anderson, Paul C, Boucher, Colette, Bousquet, Yves, Duceppe, Jean-Simon, Gillard, James, Gorys, Vida, Grand-Maître, Chantal, Grenier, Louis, Guindon, Yvan, Guse, Ingrid, Plamondon, Louis, Soucy, François, Valois, Serge, Wernic, Dominik, Yoakim, Christiane
Published in Journal of organic chemistry (30.05.1997)
Published in Journal of organic chemistry (30.05.1997)
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