Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
Xu, Miao, Lee, Emily M, Wen, Zhexing, Cheng, Yichen, Huang, Wei-Kai, Qian, Xuyu, TCW, Julia, Kouznetsova, Jennifer, Ogden, Sarah C, Hammack, Christy, Jacob, Fadi, Nguyen, Ha Nam, Itkin, Misha, Hanna, Catherine, Shinn, Paul, Allen, Chase, Michael, Samuel G, Simeonov, Anton, Huang, Wenwei, Christian, Kimberly M, Goate, Alison, Brennand, Kristen J, Huang, Ruili, Xia, Menghang, Ming, Guo-li, Zheng, Wei, Song, Hongjun, Tang, Hengli
Published in Nature medicine (01.10.2016)
Published in Nature medicine (01.10.2016)
Get full text
Journal Article
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
Griner, Lesley A. Mathews, Guha, Rajarshi, Shinn, Paul, Young, Ryan M., Keller, Jonathan M., Liu, Dongbo, Goldlust, Ian S., Yasgar, Adam, McKnight, Crystal, Boxer, Matthew B., Duveau, Damien Y., Jiang, Jian-Kang, Michael, Sam, Mierzwa, Tim, Huang, Wenwei, Walsh, Martin J., Mott, Bryan T., Patel, Paresma, Leister, William, Maloney, David J., Leclair, Christopher A., Rai, Ganesha, Jadhav, Ajit, Peyser, Brian D., Austin, Christopher P., Martin, Scott E., Simeonov, Anton, Ferrer, Marc, Staudt, Louis M., Thomas, Craig J.
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2014)
Get full text
Journal Article
Tilorone mitigates the propagation of α-synucleinopathy in a midbrain-like organoid model
Zhang, Qi, Liu, Meng, Xu, Yue, Lee, Juhyung, Jones, Brothely, Li, Bing, Huang, Wenwei, Ye, Yihong, Zheng, Wei
Published in Journal of translational medicine (02.09.2024)
Published in Journal of translational medicine (02.09.2024)
Get full text
Journal Article
Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation
Zhang, Qi, Tang, Weichun, Stancanelli, Eduardo, Jung, Eunkyung, Syed, Zulfeqhar, Pagadala, Vijayakanth, Saidi, Layla, Chen, Catherine Z., Gao, Peng, Xu, Miao, Pavlinov, Ivan, Li, Bing, Huang, Wenwei, Chen, Liqiang, Liu, Jian, Xie, Hang, Zheng, Wei, Ye, Yihong
Published in Nature communications (18.09.2023)
Published in Nature communications (18.09.2023)
Get full text
Journal Article
A Selective TSH Receptor Antagonist Inhibits Stimulation of Thyroid Function in Female Mice
Neumann, Susanne, Nir, Eshel A, Eliseeva, Elena, Huang, Wenwei, Marugan, Juan, Xiao, Jingbo, Dulcey, Andrés E, Gershengorn, Marvin C
Published in Endocrinology (Philadelphia) (01.01.2014)
Published in Endocrinology (Philadelphia) (01.01.2014)
Get full text
Journal Article
Chemical signatures and new drug targets for gametocytocidal drug development
Sun, Wei, Tanaka, Takeshi Q., Magle, Crystal T., Huang, Wenwei, Southall, Noel, Huang, Ruili, Dehdashti, Seameen J., McKew, John C., Williamson, Kim C., Zheng, Wei
Published in Scientific reports (17.01.2014)
Published in Scientific reports (17.01.2014)
Get full text
Journal Article
Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy
Law, Amanda J, Wang, Yanhong, Sei, Yoshitatsu, O’Donnell, Patricio, Piantadosi, Patrick, Papaleo, Francesco, Straub, Richard E, Huang, Wenwei, Thomas, Craig J, Vakkalanka, Radhakrishna, Besterman, Aaron D, Lipska, Barbara K, Hyde, Thomas M, Harrison, Paul J, Kleinman, Joel E, Weinberger, Daniel R
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2012)
Get full text
Journal Article
Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model
Papaleo, Francesco, Yang, Feng, Paterson, Clare, Palumbo, Sara, Carr, Gregory V, Wang, Yanhong, Floyd, Kirsten, Huang, Wenwei, Thomas, Craig J, Chen, Jingshan, Weinberger, Daniel R, Law, Amanda J
Published in The Journal of neuroscience (27.04.2016)
Published in The Journal of neuroscience (27.04.2016)
Get full text
Journal Article
Use of physiological based pharmacokinetic modeling for cross-species prediction of pharmacokinetic and tissue distribution profiles of a novel niclosamide prodrug
Yang, Mengbi, Wang, Amy Q, Padilha, Elias C, Shah, Pranav, Hagen, Natalie R, Ryu, China, Shamim, Khalida, Huang, Wenwei, Xu, Xin
Published in Frontiers in pharmacology (11.04.2023)
Published in Frontiers in pharmacology (11.04.2023)
Get full text
Journal Article
The SARS-CoV‑2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules
Gorshkov, Kirill, Chen, Catherine Z, Bostwick, Robert, Rasmussen, Lynn, Tran, Bruce Nguyen, Cheng, Yu-Shan, Xu, Miao, Pradhan, Manisha, Henderson, Mark, Zhu, Wei, Oh, Eunkeu, Susumu, Kimihiro, Wolak, Mason, Shamim, Khalida, Huang, Wenwei, Hu, Xin, Shen, Min, Klumpp-Thomas, Carleen, Itkin, Zina, Shinn, Paul, Carlos de la Torre, Juan, Simeonov, Anton, Michael, Sam G, Hall, Matthew D, Lo, Donald C, Zheng, Wei
Published in ACS infectious diseases (11.06.2021)
Published in ACS infectious diseases (11.06.2021)
Get full text
Journal Article
Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, a Potential Oral Drug Candidate for COVID-19 Treatment
Wang, Amy Q., Hagen, Natalie R., Padilha, Elias C., Yang, Mengbi, Shah, Pranav, Chen, Catherine Z., Huang, Wenwei, Terse, Pramod, Sanderson, Philip, Zheng, Wei, Xu, Xin
Published in Frontiers in pharmacology (16.08.2022)
Published in Frontiers in pharmacology (16.08.2022)
Get full text
Journal Article
De Novo Assembly, Characterization and Comparative Transcriptome Analysis of the Mature Gonads in Spinibarbus hollandi
Han, Chong, Huang, Wenwei, Peng, Suhan, Zhou, Jiangwei, Zhan, Huawei, Zhang, Yuying, Li, Wenjun, Gong, Jian, Li, Qiang
Published in Animals (Basel) (31.12.2022)
Published in Animals (Basel) (31.12.2022)
Get full text
Journal Article
LncRNA LINC00470 promotes proliferation through association with NF45/NF90 complex in hepatocellular carcinoma
Huang, Wenwei, Liu, Juntao, Yan, Jijun, Huang, Zhengbin, Zhang, Xiongjie, Mao, Yanping, Huang, Xiufang
Published in Human cell : official journal of Human Cell Research Society (2020)
Published in Human cell : official journal of Human Cell Research Society (2020)
Get full text
Journal Article
A New Small-Molecule Antagonist Inhibits Graves' Disease Antibody Activation of the TSH Receptor
Neumann, Susanne, Eliseeva, Elena, McCoy, Joshua G, Napolitano, Giorgio, Giuliani, Cesidio, Monaco, Fabrizio, Huang, Wenwei, Gershengorn, Marvin C
Published in The journal of clinical endocrinology and metabolism (01.02.2011)
Published in The journal of clinical endocrinology and metabolism (01.02.2011)
Get full text
Journal Article
Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites
Dorjsuren, Dorjbal, Eastman, Richard T., Wicht, Kathryn J., Jansen, Daniel, Talley, Daniel C., Sigmon, Benjamin A., Zakharov, Alexey V., Roncal, Norma, Girvin, Andrew T., Antonova-Koch, Yevgeniya, Will, Paul M., Shah, Pranav, Sun, Hongmao, Klumpp-Thomas, Carleen, Mok, Sachel, Yeo, Tomas, Meister, Stephan, Marugan, Juan Jose, Ross, Leila S., Xu, Xin, Maloney, David J., Jadhav, Ajit, Mott, Bryan T., Sciotti, Richard J., Winzeler, Elizabeth A., Waters, Norman C., Campbell, Robert F., Huang, Wenwei, Simeonov, Anton, Fidock, David A.
Published in Scientific reports (22.01.2021)
Published in Scientific reports (22.01.2021)
Get full text
Journal Article