CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population
Mirghani, Rajaa A, Sayi, Jane, Aklillu, Eleni, Allqvist, Annika, Jande, Mary, Wennerholm, Agneta, Eriksen, Jaran, Herben, Virginie M M, Jones, Barry C, Gustafsson, Lars L, Bertilsson, Leif
Published in Pharmacogenetics and genomics (01.09.2006)
Published in Pharmacogenetics and genomics (01.09.2006)
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Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo
WENNERHOLM, Agneta, NORDMARK, Anna, PIHISGARD, Maria, MAHINDI, Margarita, BERTILSSON, Leif, GUSTAFSSON, Lars L
Published in European journal of clinical pharmacology (01.07.2006)
Published in European journal of clinical pharmacology (01.07.2006)
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Simultaneous quantification of alprazolam, 4- and α-hydroxyalprazolam in plasma samples using liquid chromatography mass spectrometry
Allqvist, Annika, Wennerholm, Agneta, Svensson, Jan-Olof, Mirghani, Rajaa A.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.01.2005)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.01.2005)
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Characterization of the CYP2D629 allele commonly present in a black Tanzanian population causing reduced catalytic activity
Wennerholm, A, Johansson, I, Hidestrand, M, Bertilsson, L, Gustafsson, L L, Ingelman-Sundberg, M
Published in Pharmacogenetics (London) (01.07.2001)
Published in Pharmacogenetics (London) (01.07.2001)
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The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity
Wennerholm, Agneta, Dandara, Collet, Sayi, Jane, Svensson, Jan-Olov, Abdi, Yakoub Aden, Ingelman-Sundberg, Magnus, Bertilsson, Leif, Hasler, Julia, Gustafsson, Lars L
Published in Clinical pharmacology and therapeutics (01.01.2002)
Published in Clinical pharmacology and therapeutics (01.01.2002)
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Analysis of CYP2C95 in Caucasian, Oriental and Black-African populations
YASAR, Ümit, AKLILLU, Eleni, CANAPARO, Roberto, SANDBERG, Mia, SAYI, Jane, ROH, Hyung-Keun, WENNERHOLM, Agneta
Published in European journal of clinical pharmacology (01.11.2002)
Published in European journal of clinical pharmacology (01.11.2002)
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Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of [alpha]- and 4-hydroxy metabolites in healthy subjects
Wennerholm, Agneta, Allqvist, Annika, Svensson, Jan-Olof, Gustafsson, Lars L, Mirghani, Rajaa A, Bertilsson, Leif
Published in European journal of clinical pharmacology (01.04.2005)
Published in European journal of clinical pharmacology (01.04.2005)
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Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype
Herrlin, K, Massele, A Y, Jande, M, Alm, C, Tybring, G, Abdi, Y A, Wennerholm, A, Johansson, I, Dahl, M L, Bertilsson, L, Gustafsson, L L
Published in Clinical pharmacology and therapeutics (01.10.1998)
Published in Clinical pharmacology and therapeutics (01.10.1998)
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Alprazolam as a probe for CYP3A using a single blood sample : pharmacokinetics of parent drug, and of α- and 4-hydroxy metabolites in healthy subjects
WENNERHOLM, Agneta, ALLQVIST, Annika, SVENSSON, Jan-Olof, GUSTAFSSON, Lars L, MIRGHANI, Rajaa A, BERTILSSON, Leif
Published in European journal of clinical pharmacology (01.04.2005)
Published in European journal of clinical pharmacology (01.04.2005)
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Ten percent of North Spanish individuals carry duplicated or triplicated CYP2D6 genes associated with ultrarapid metabolism of debrisoquine
Bernal, M L, Sinues, B, Johansson, I, McLellan, R A, Wennerholm, A, Dahl, M L, Ingelman-Sundberg, M, Bertilsson, L
Published in Pharmacogenetics (London) (01.10.1999)
Published in Pharmacogenetics (London) (01.10.1999)
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Decreased capacity for debrisoquine metabolism among black Tanzanians: analyses of the CYP2D6 genotype and phenotype
Wennerholm, A, Johansson, I, Massele, A Y, Lande, M, Alm, C, Aden-Abdi, Y, Dahl, M L, Ingelman-Sundberg, M, Bertilsson, L, Gustafsson, L L
Published in Pharmacogenetics (London) (01.12.1999)
Published in Pharmacogenetics (London) (01.12.1999)
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