Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System
Umek, Tea, Olsson, Thomas, Gissberg, Olof, Saher, Osama, Zaghloul, Eman M, Lundin, Karin E, Wengel, Jesper, Hanse, Eric, Zetterberg, Henrik, Vizlin-Hodzic, Dzeneta, Smith, C I Edvard, Zain, Rula
Published in Nucleic acid therapeutics (01.12.2021)
Published in Nucleic acid therapeutics (01.12.2021)
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Sequence and pH Effects of LNA-Containing Triple Helix-Forming Oligonucleotides: Physical Chemistry, Biochemistry, and Modeling Studies
Sun, Bei-Wen, Babu, B. Ravindra, Sørensen, Mads D, Zakrzewska, Krystyna, Wengel, Jesper, Sun, Jian-Sheng
Published in Biochemistry (Easton) (13.04.2004)
Published in Biochemistry (Easton) (13.04.2004)
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Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities
Brunet, Erika, Corgnali, Maddalena, Perrouault, Loïc, Roig, Victoria, Asseline, Ulysse, Sørensen, Mads D., Babu, B. Ravindra, Wengel, Jesper, Giovannangeli, Carine
Published in Nucleic acids research (01.01.2005)
Published in Nucleic acids research (01.01.2005)
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X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer
Egli, Martin, Teplova, Marianna, Minasov, George, Kumar, Ravindra, Wengel, Jesper
Published in Chemical communications (Cambridge, England) (01.01.2001)
Published in Chemical communications (Cambridge, England) (01.01.2001)
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α-l-LNA (α-i-r ibo Configured Locked Nucleic Acid) Recognition of RNA. A Study by NMR Spectroscopy and Molecular Dynamics Simulations
Petersen, Michael, Håkansson, Anders E, Wengel, Jesper, Jacobsen, Jens Peter
Published in Journal of the American Chemical Society (01.08.2001)
Published in Journal of the American Chemical Society (01.08.2001)
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Synthesis of a Novel Bicyclic Nucleoside Restricted to an S-Type Conformation and Initial Evaluation of Its Hybridization Properties When Incorporated into Oligodeoxynucleotides
Kværnø, Lisbet, Wightman, Richard H, Wengel, Jesper
Published in Journal of organic chemistry (27.07.2001)
Published in Journal of organic chemistry (27.07.2001)
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Improved RNA cleavage by LNAzyme derivatives of DNAzymes
Vester, B, Lundberg, L B, Sørensen, M D, Babu, B R, Douthwaite, S, Wengel, J
Published in Biochemical Society transactions (01.02.2004)
Published in Biochemical Society transactions (01.02.2004)
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ADAMTS-targeting gapmers as a gene modulation strategy in osteoarthritis
Garcia, J., Wengel, J., Howard, K.A., Creemers, L.B.
Published in Osteoarthritis and cartilage (01.04.2020)
Published in Osteoarthritis and cartilage (01.04.2020)
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Fibrin-hyaluronic acid hydrogel-based delivery of antisense oligonucleotides for ADAMTS5 inhibition in co-delivered and resident joint cells in osteoarthritis
Garcia, João Pedro, Stein, Jeroen, Cai, Yunpeng, Riemers, Frank, Wexselblatt, Ezequiel, Wengel, Jesper, Tryfonidou, Marianna, Yayon, Avner, Howard, Kenneth A., Creemers, Laura B.
Published in Journal of controlled release (28.01.2019)
Published in Journal of controlled release (28.01.2019)
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