Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
Johnson, Marc O., Wolf, Melissa M., Madden, Matthew Z., Andrejeva, Gabriela, Sugiura, Ayaka, Contreras, Diana C., Maseda, Damian, Liberti, Maria V., Paz, Katelyn, Kishton, Rigel J., Johnson, Matthew E., de Cubas, Aguirre A., Wu, Pingsheng, Li, Gongbo, Zhang, Yongliang, Newcomb, Dawn C., Wells, Andrew D., Restifo, Nicholas P., Rathmell, W. Kimryn, Locasale, Jason W., Davila, Marco L., Blazar, Bruce R., Rathmell, Jeffrey C.
Published in Cell (13.12.2018)
Published in Cell (13.12.2018)
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Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density
Chesi, Alessandra, Wagley, Yadav, Johnson, Matthew E., Manduchi, Elisabetta, Su, Chun, Lu, Sumei, Leonard, Michelle E., Hodge, Kenyaita M., Pippin, James A., Hankenson, Kurt D., Wells, Andrew D., Grant, Struan F. A.
Published in Nature communications (19.03.2019)
Published in Nature communications (19.03.2019)
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A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression
Gallagher, Michael D., Posavi, Marijan, Huang, Peng, Unger, Travis L., Berlyand, Yosef, Gruenewald, Analise L., Chesi, Alessandra, Manduchi, Elisabetta, Wells, Andrew D., Grant, Struan F.A., Blobel, Gerd A., Brown, Christopher D., Chen-Plotkin, Alice S.
Published in American journal of human genetics (02.11.2017)
Published in American journal of human genetics (02.11.2017)
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Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells
Su, Chun, Johnson, Matthew E., Torres, Annabel, Thomas, Rajan M., Manduchi, Elisabetta, Sharma, Prabhat, Mehra, Parul, Le Coz, Carole, Leonard, Michelle E., Lu, Sumei, Hodge, Kenyaita M., Chesi, Alessandra, Pippin, James, Romberg, Neil, Grant, Struan F. A., Wells, Andrew D.
Published in Nature communications (03.07.2020)
Published in Nature communications (03.07.2020)
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Implicating effector genes at COVID-19 GWAS loci using promoter-focused Capture-C in disease-relevant immune cell types
Pahl, Matthew C, Le Coz, Carole, Su, Chun, Sharma, Prabhat, Thomas, Rajan M, Pippin, James A, Cruz Cabrera, Emylette, Johnson, Matthew E, Leonard, Michelle E, Lu, Sumei, Chesi, Alessandra, Sullivan, Kathleen E, Romberg, Neil, Grant, Struan F A, Wells, Andrew D
Published in Genome Biology (03.06.2022)
Published in Genome Biology (03.06.2022)
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Mbd2 Promotes Foxp3 Demethylation and T-Regulatory-Cell Function
Wang, Liqing, Liu, Yujie, Han, Rongxiang, Beier, Ulf H., Thomas, Rajan M., Wells, Andrew D., Hancock, Wayne W.
Published in Molecular and Cellular Biology (01.10.2013)
Published in Molecular and Cellular Biology (01.10.2013)
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Conserved Intergenic Elements and DNA Methylation Cooperate to Regulate Transcription at the il17 Locus
Thomas, Rajan M., Sai, Hong, Wells, Andrew D.
Published in The Journal of biological chemistry (20.07.2012)
Published in The Journal of biological chemistry (20.07.2012)
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Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival
Katerndahl, Casey D S, Heltemes-Harris, Lynn M, Willette, Mark J L, Henzler, Christine M, Frietze, Seth, Yang, Rendong, Schjerven, Hilde, Silverstein, Kevin A T, Ramsey, Laura B, Hubbard, Gregory, Wells, Andrew D, Kuiper, Roland P, Scheijen, Blanca, van Leeuwen, Frank N, Müschen, Markus, Kornblau, Steven M, Farrar, Michael A
Published in Nature immunology (01.06.2017)
Published in Nature immunology (01.06.2017)
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Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
Thomas, Rajan M, Pahl, Matthew C, Wang, Liqing, Grant, Struan F A, Hancock, Wayne W, Wells, Andrew D
Published in eLife (24.04.2024)
Published in eLife (24.04.2024)
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Cyclin-dependent kinase 2 controls peripheral immune tolerance
Chunder, Neelanjana, Wang, Liqing, Chen, Chunxia, Hancock, Wayne W, Wells, Andrew D
Published in The Journal of immunology (1950) (15.12.2012)
Published in The Journal of immunology (1950) (15.12.2012)
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Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease
Layman, Awo Akosua Kesewa, Deng, Guoping, O’Leary, Claire E., Tadros, Samuel, Thomas, Rajan M., Dybas, Joseph M., Moser, Emily K., Wells, Andrew D., Doliba, Nicolai M., Oliver, Paula M.
Published in Nature communications (05.06.2017)
Published in Nature communications (05.06.2017)
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Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human Liver
Çalışkan, Minal, Manduchi, Elisabetta, Rao, H. Shanker, Segert, Julian A., Beltrame, Marcia Holsbach, Trizzino, Marco, Park, YoSon, Baker, Samuel W., Chesi, Alessandra, Johnson, Matthew E., Hodge, Kenyaita M., Leonard, Michelle E., Loza, Baoli, Xin, Dong, Berrido, Andrea M., Hand, Nicholas J., Bauer, Robert C., Wells, Andrew D., Olthoff, Kim M., Shaked, Abraham, Rader, Daniel J., Grant, Struan F.A., Brown, Christopher D.
Published in American journal of human genetics (03.07.2019)
Published in American journal of human genetics (03.07.2019)
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Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate
Arnold, Preston R, Wells, Andrew D, Li, Xian C
Published in Frontiers in cell and developmental biology (14.01.2020)
Published in Frontiers in cell and developmental biology (14.01.2020)
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Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci
Hammond, Reza K, Pahl, Matthew C, Su, Chun, Cousminer, Diana L, Leonard, Michelle E, Lu, Sumei, Doege, Claudia A, Wagley, Yadav, Hodge, Kenyaita M, Lasconi, Chiara, Johnson, Matthew E, Pippin, James A, Hankenson, Kurt D, Leibel, Rudolph L, Chesi, Alessandra, Wells, Andrew D, Grant, Struan Fa
Published in eLife (18.01.2021)
Published in eLife (18.01.2021)
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Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation
Pahl, Matthew C, Sharma, Prabhat, Thomas, Rajan M, Thompson, Zachary, Mount, Zachary, Pippin, James A, Morawski, Peter A, Sun, Peng, Su, Chun, Campbell, Daniel, Grant, Struan F A, Wells, Andrew D
Published in eLife (20.09.2024)
Published in eLife (20.09.2024)
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Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits
Pahl, Matthew C., Doege, Claudia A., Hodge, Kenyaita M., Littleton, Sheridan H., Leonard, Michelle E., Lu, Sumei, Rausch, Rick, Pippin, James A., De Rosa, Maria Caterina, Basak, Alisha, Bradfield, Jonathan P., Hammond, Reza K., Boehm, Keith, Berkowitz, Robert I., Lasconi, Chiara, Su, Chun, Chesi, Alessandra, Johnson, Matthew E., Wells, Andrew D., Voight, Benjamin F., Leibel, Rudolph L., Cousminer, Diana L., Grant, Struan F. A.
Published in Nature communications (19.11.2021)
Published in Nature communications (19.11.2021)
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Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual
Cousminer, Diana L, Wagley, Yadav, Pippin, James A, Elhakeem, Ahmed, Way, Gregory P, Pahl, Matthew C, McCormack, Shana E, Chesi, Alessandra, Mitchell, Jonathan A, Kindler, Joseph M, Baird, Denis, Hartley, April, Howe, Laura, Kalkwarf, Heidi J, Lappe, Joan M, Lu, Sumei, Leonard, Michelle E, Johnson, Matthew E, Hakonarson, Hakon, Gilsanz, Vicente, Shepherd, John A, Oberfield, Sharon E, Greene, Casey S, Kelly, Andrea, Lawlor, Deborah A, Voight, Benjamin F, Wells, Andrew D, Zemel, Babette S, Hankenson, Kurt D, Grant, Struan F A
Published in Genome Biology (04.01.2021)
Published in Genome Biology (04.01.2021)
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Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function
Song, Xiaomin, Li, Bin, Xiao, Yan, Chen, Chunxia, Wang, Qiang, Liu, Yujie, Berezov, Alan, Xu, Chen, Gao, Yayi, Li, Zhiyuan, Wu, Shiaw-Lin, Cai, Zheng, Zhang, Hongtao, Karger, Barry L., Hancock, Wayne W., Wells, Andrew D., Zhou, Zhaocai, Greene, Mark I.
Published in Cell reports (Cambridge) (28.06.2012)
Published in Cell reports (Cambridge) (28.06.2012)
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