Total Synthesis of (+)-Linoxepin by Utilizing the Catellani Reaction
Weinstabl, Harald, Suhartono, Marcel, Qureshi, Zafar, Lautens, Mark
Published in Angewandte Chemie International Edition (10.05.2013)
Published in Angewandte Chemie International Edition (10.05.2013)
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A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
Kofink, Christiane, Trainor, Nicole, Mair, Barbara, Wöhrle, Simon, Wurm, Melanie, Mischerikow, Nikolai, Roy, Michael J., Bader, Gerd, Greb, Peter, Garavel, Géraldine, Diers, Emelyne, McLennan, Ross, Whitworth, Claire, Vetma, Vesna, Rumpel, Klaus, Scharnweber, Maximilian, Fuchs, Julian E., Gerstberger, Thomas, Cui, Yunhai, Gremel, Gabriela, Chetta, Paolo, Hopf, Stefan, Budano, Nicole, Rinnenthal, Joerg, Gmaschitz, Gerhard, Mayer, Moriz, Koegl, Manfred, Ciulli, Alessio, Weinstabl, Harald, Farnaby, William
Published in Nature communications (10.10.2022)
Published in Nature communications (10.10.2022)
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Additive Effects in the Palladium-Catalyzed Carboiodination of Chiral N-Allyl Carboxamides
Petrone, David A., Yoon, Hyung, Weinstabl, Harald, Lautens, Mark
Published in Angewandte Chemie International Edition (21.07.2014)
Published in Angewandte Chemie International Edition (21.07.2014)
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Journal Article
Synthesis of the Lycopodium Alkaloid (+)-Lycoflexine
Ramharter, Jürgen, Weinstabl, Harald, Mulzer, Johann
Published in Journal of the American Chemical Society (20.10.2010)
Published in Journal of the American Chemical Society (20.10.2010)
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Journal Article
Discovery of Novel Spiro[3H‑indole-3,2′-pyrrolidin]-2(1H)‑one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2–p53 Interaction
Gollner, Andreas, Rudolph, Dorothea, Arnhof, Heribert, Bauer, Markus, Blake, Sophia M, Boehmelt, Guido, Cockroft, Xiao-Ling, Dahmann, Georg, Ettmayer, Peter, Gerstberger, Thomas, Karolyi-Oezguer, Jale, Kessler, Dirk, Kofink, Christiane, Ramharter, Juergen, Rinnenthal, Jörg, Savchenko, Alexander, Schnitzer, Renate, Weinstabl, Harald, Weyer-Czernilofsky, Ulrike, Wunberg, Tobias, McConnell, Darryl B
Published in Journal of medicinal chemistry (23.11.2016)
Published in Journal of medicinal chemistry (23.11.2016)
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Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor
Bröker, Joachim, Waterson, Alex G., Smethurst, Chris, Kessler, Dirk, Böttcher, Jark, Mayer, Moriz, Gmaschitz, Gerhard, Phan, Jason, Little, Andrew, Abbott, Jason R., Sun, Qi, Gmachl, Michael, Rudolph, Dorothea, Arnhof, Heribert, Rumpel, Klaus, Savarese, Fabio, Gerstberger, Thomas, Mischerikow, Nikolai, Treu, Matthias, Herdeis, Lorenz, Wunberg, Tobias, Gollner, Andreas, Weinstabl, Harald, Mantoulidis, Andreas, Krämer, Oliver, McConnell, Darryl B., W. Fesik, Stephen
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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opnMe.com: a digital initiative for sharing tools with the biomedical research community
Gollner, Andreas, Köster, Markus, Nicklin, Paul, Trieselmann, Thomas, Klein, Elliott, Vlach, Jaromir, Heine, Claudia, Grundl, Marc, Ramharter, Jürgen, Wyatt, David, Chaturvedi, Menorca, Ciulli, Alessio, Carter, Katharine C., Müller, Susanne, Bischoff, Daniel, Ettmayer, Peter, Haaksma, Eric, Mack, Jürgen, McConnell, Darryl, Stenkamp, Dirk, Weinstabl, Harald, Zentgraf, Matthias, Wood, Clive R., Montel, Florian
Published in Nature reviews. Drug discovery (01.07.2022)
Published in Nature reviews. Drug discovery (01.07.2022)
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Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria
Junk, Lukas, Schmiedel, Volker M., Guha, Somraj, Fischel, Katharina, Greb, Peter, Vill, Kristin, Krisilia, Violetta, van Geelen, Lasse, Rumpel, Klaus, Kaur, Parvinder, Krishnamurthy, Ramya V., Narayanan, Shridhar, Shandil, Radha Krishan, Singh, Mayas, Kofink, Christiane, Mantoulidis, Andreas, Biber, Philipp, Gmaschitz, Gerhard, Kazmaier, Uli, Meinhart, Anton, Leodolter, Julia, Hoi, David, Junker, Sabryna, Morreale, Francesca Ester, Clausen, Tim, Kalscheuer, Rainer, Weinstabl, Harald, Boehmelt, Guido
Published in Nature communications (05.03.2024)
Published in Nature communications (05.03.2024)
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Journal Article
Circulating procoagulant microparticles in cancer patients
Thaler, Johannes, Ay, Cihan, Weinstabl, Harald, Dunkler, Daniela, Simanek, Ralph, Vormittag, Rainer, Freyssinet, Jean-Marie, Zielinski, Christoph, Pabinger, Ingrid
Published in Annals of hematology (01.04.2011)
Published in Annals of hematology (01.04.2011)
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Inhibition of p53-MDM2 binding reduces senescent cell abundance and improves the adaptive responses of skeletal muscle from aged mice
Nolt, Georgia L., Keeble, Alexander R., Wen, Yuan, Strong, Aubrey C., Thomas, Nicholas T., Valentino, Taylor R., Brightwell, Camille R., Murach, Kevin A., Patrizia, Sini, Weinstabl, Harald, Gollner, Andreas, McCarthy, John J., Fry, Christopher S., Franti, Michael, Filareto, Antonio, Peterson, Charlotte A., Dungan, Cory M.
Published in GeroScience (01.04.2024)
Published in GeroScience (01.04.2024)
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Journal Article
Electrochemical Umpolung C–H Functionalization of Oxindoles
Pastor, Miryam, Vayer, Marie, Weinstabl, Harald, Maulide, Nuno
Published in Journal of organic chemistry (07.01.2022)
Published in Journal of organic chemistry (07.01.2022)
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Journal Article
Intermolecular Domino Reaction of Two Aryl Iodides Involving Two CH Functionalizations
Sickert, Marcel, Weinstabl, Harald, Peters, Brendan, Hou, Xiao, Lautens, Mark
Published in Angewandte Chemie International Edition (12.05.2014)
Published in Angewandte Chemie International Edition (12.05.2014)
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BacPROTACs mediate targeted protein degradation in bacteria
Morreale, Francesca E., Kleine, Stefan, Leodolter, Julia, Junker, Sabryna, Hoi, David M., Ovchinnikov, Stepan, Okun, Anastasia, Kley, Juliane, Kurzbauer, Robert, Junk, Lukas, Guha, Somraj, Podlesainski, David, Kazmaier, Uli, Boehmelt, Guido, Weinstabl, Harald, Rumpel, Klaus, Schmiedel, Volker M., Hartl, Markus, Haselbach, David, Meinhart, Anton, Kaiser, Markus, Clausen, Tim
Published in Cell (23.06.2022)
Published in Cell (23.06.2022)
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Journal Article
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
Farnaby, William, Koegl, Manfred, Roy, Michael J., Whitworth, Claire, Diers, Emelyne, Trainor, Nicole, Zollman, David, Steurer, Steffen, Karolyi-Oezguer, Jale, Riedmueller, Carina, Gmaschitz, Teresa, Wachter, Johannes, Dank, Christian, Galant, Michael, Sharps, Bernadette, Rumpel, Klaus, Traxler, Elisabeth, Gerstberger, Thomas, Schnitzer, Renate, Petermann, Oliver, Greb, Peter, Weinstabl, Harald, Bader, Gerd, Zoephel, Andreas, Weiss-Puxbaum, Alexander, Ehrenhöfer-Wölfer, Katharina, Wöhrle, Simon, Boehmelt, Guido, Rinnenthal, Joerg, Arnhof, Heribert, Wiechens, Nicola, Wu, Meng-Ying, Owen-Hughes, Tom, Ettmayer, Peter, Pearson, Mark, McConnell, Darryl B., Ciulli, Alessio
Published in Nature chemical biology (01.07.2019)
Published in Nature chemical biology (01.07.2019)
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Journal Article
Synthesis of MDM2-p53 Inhibitor BI-0282 via a Dipolar Cycloaddition and Late-Stage Davis–Beirut Reaction
Ramharter, Juergen, Kulhanek, Michael, Dettling, Maike, Gmaschitz, Gerhard, Karolyi-Oezguer, Jale, Weinstabl, Harald, Gollner, Andreas
Published in Organic process research & development (19.08.2022)
Published in Organic process research & development (19.08.2022)
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Journal Article
Synthesis of a 13C-methylene-labeled isoleucine precursor as a useful tool for studying protein side-chain interactions and dynamics
Höfurthner, Theresa, Toscano, Giorgia, Kontaxis, Georg, Beier, Andreas, Mayer, Moriz, Geist, Leonhard, McConnell, Darryl B., Weinstabl, Harald, Lichtenecker, Roman, Konrat, Robert
Published in Journal of biomolecular NMR (01.03.2024)
Published in Journal of biomolecular NMR (01.03.2024)
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Journal Article
Light-Mediated Total Synthesis of 17-Deoxyprovidencin
Toelle, Nina, Weinstabl, Harald, Gaich, Tanja, Mulzer, Johann
Published in Angewandte Chemie International Edition (07.04.2014)
Published in Angewandte Chemie International Edition (07.04.2014)
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Journal Article
13 Cβ‐Valine and 13 Cγ‐Leucine Methine Labeling To Probe Protein Ligand Interaction
Toscano, Giorgia, Höfurthner, Theresa, Nagl, Benjamin, Beier, Andreas, Mayer, Moriz, Geist, Leonhard, McConnell, Darryl B., Weinstabl, Harald, Konrat, Robert, Lichtenecker, Roman J.
Published in Chembiochem : a European journal of chemical biology (15.03.2024)
Published in Chembiochem : a European journal of chemical biology (15.03.2024)
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