Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models
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Published in Neurobiology of disease (01.04.2019)
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Fibronectin-guided migration of carcinoma collectives
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Published in Nature communications (19.01.2017)
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Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life
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Published in Nature neuroscience (01.12.2020)
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Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro
Nobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A., Hock, Christoph, Nitsch, Roger M., Montrasio, Fabio, Grimm, Jan, Cheung, Anne E., Dunah, Anthone W., Wittmann, Marion, Bussiere, Thierry, Weinreb, Paul H., Hyman, Bradley T., Takeda, Shuko
Published in The American journal of pathology (01.06.2017)
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Characterization of tau binding by gosuranemab
Sopko, Richelle, Golonzhka, Olga, Arndt, Joseph, Quan, Chao, Czerkowicz, Julie, Cameron, Andrew, Smith, Benjamin, Murugesan, Yogapriya, Gibbons, Garrett, Kim, Soo-Jung, Trojanowski, John Q., Lee, Virginia M.Y., Brunden, Kurt R., Graham, Danielle L., Weinreb, Paul H., Hering, Heike
Published in Neurobiology of disease (01.12.2020)
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Aggregated SOD1 causes selective death of cultured human motor neurons
Benkler, Chen, O’Neil, Alison L., Slepian, Susannah, Qian, Fang, Weinreb, Paul H., Rubin, Lee L.
Published in Scientific reports (06.11.2018)
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Stromal features are predictive of disease mortality in oral cancer patients
Marsh, Daniel, Suchak, Krishna, Moutasim, Karwan A, Vallath, Sabarinath, Hopper, Colin, Jerjes, Waseem, Upile, Tahwinder, Kalavrezos, Nicholas, Violette, Shelia M, Weinreb, Paul H, Chester, Kerry A, Chana, Jagdeep S, Marshall, John F, Hart, Ian R, Hackshaw, Allan K, Piper, Kim, Thomas, Gareth J
Published in The Journal of pathology (01.03.2011)
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Tatler, Amanda L, Goodwin, Amanda T, Gbolahan, Olumide, Saini, Gauri, Porte, Joanne, John, Alison E, Clifford, Rachel L, Violette, Shelia M, Weinreb, Paul H, Parfrey, Helen, Wolters, Paul J, Gauldie, Jack, Kolb, Martin, Jenkins, Gisli
Published in PloS one (05.08.2016)
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Overexpression of Fibroblast Growth Factor-10 during Both Inflammatory and Fibrotic Phases Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice
Gupte, Varsha V, Ramasamy, Suresh K, Reddy, Raghava, Lee, Jooeun, Weinreb, Paul H, Violette, Shelia M, Guenther, Andreas, Warburton, David, Driscoll, Barbara, Minoo, Parviz, Bellusci, Saverio
Published in American journal of respiratory and critical care medicine (01.09.2009)
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Monoclonal antibody exposure in rat and cynomolgus monkey cerebrospinal fluid following systemic administration
Wang, Qin, Delva, Luisette, Weinreb, Paul H, Pepinsky, Robert B, Graham, Danielle, Veizaj, Elvana, Cheung, Anne E, Chen, Weiping, Nestorov, Ivan, Rohde, Ellen, Caputo, Robin, Kuesters, Geoffrey M, Bohnert, Tonika, Gan, Liang-Shang
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Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression
Quaglia, Fabio, Krishn, Shiv Ram, Wang, Yanqing, Goodrich, David W, McCue, Peter, Kossenkov, Andrew V, Mandigo, Amy C, Knudsen, Karen E, Weinreb, Paul H, Corey, Eva, Kelly, William K, Languino, Lucia R
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The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis
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Published in Journal of extracellular vesicles (01.01.2020)
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Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis
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Published in The Journal of pathology (01.02.2011)
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Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis
Shea, Barry S, Probst, Clemens K, Brazee, Patricia L, Rotile, Nicholas J, Blasi, Francesco, Weinreb, Paul H, Black, Katharine E, Sosnovik, David E, Van Cott, Elizabeth M, Violette, Shelia M, Caravan, Peter, Tager, Andrew M
Published in JCI insight (04.05.2017)
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Inhibition of integrin αVβ6 changes fibril thickness of stromal collagen in experimental carcinomas
Olof Olsson, P., Gustafsson, Renata, Salnikov, Alexei V., Göthe, Maria, Zeller, Kathrin S., Friman, Tomas, Baldetorp, Bo, Koopman, Louise A., Weinreb, Paul H., Violette, Shelia M., Kalamajski, Sebastian, Heldin, Nils-Erik, Rubin, Kristofer
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The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease
Sevigny, Jeff, Chiao, Ping, Bussière, Thierry, Weinreb, Paul H., Williams, Leslie, Maier, Marcel, Dunstan, Robert, Salloway, Stephen, Chen, Tianle, Ling, Yan, O’Gorman, John, Qian, Fang, Arastu, Mahin, Li, Mingwei, Chollate, Sowmya, Brennan, Melanie S., Quintero-Monzon, Omar, Scannevin, Robert H., Arnold, H. Moore, Engber, Thomas, Rhodes, Kenneth, Ferrero, James, Hang, Yaming, Mikulskis, Alvydas, Grimm, Jan, Hock, Christoph, Nitsch, Roger M., Sandrock, Alfred
Published in Nature (London) (01.09.2016)
Published in Nature (London) (01.09.2016)
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NACP, A Protein Implicated in Alzheimer's Disease and Learning, Is Natively Unfolded
Weinreb, Paul H, Zhen, Weiguo, Poon, Anna W, Conway, Kelly A, Lansbury, Peter T
Published in Biochemistry (Easton) (29.10.1996)
Published in Biochemistry (Easton) (29.10.1996)
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Characterization of Sfp, a Bacillus subtilis Phosphopantetheinyl Transferase for Peptidyl Carrier Protein Domains in Peptide Synthetases
Quadri, Luis E. N, Weinreb, Paul H, Lei, Ming, Nakano, Michiko M, Zuber, Peter, Walsh, Christopher T
Published in Biochemistry (Easton) (10.02.1998)
Published in Biochemistry (Easton) (10.02.1998)
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Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β
Arndt, Joseph W., Qian, Fang, Smith, Benjamin A., Quan, Chao, Kilambi, Krishna Praneeth, Bush, Martin W., Walz, Thomas, Pepinsky, R. Blake, Bussière, Thierry, Hamann, Stefan, Cameron, Thomas O., Weinreb, Paul H.
Published in Scientific reports (23.04.2018)
Published in Scientific reports (23.04.2018)
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Immunotherapy with Aducanumab Restores Calcium Homeostasis in Tg2576 Mice
Kastanenka, Ksenia V, Bussiere, Thierry, Shakerdge, Naomi, Qian, Fang, Weinreb, Paul H, Rhodes, Ken, Bacskai, Brian J
Published in The Journal of neuroscience (14.12.2016)
Published in The Journal of neuroscience (14.12.2016)
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