Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses
Bos, Rinke, Rutten, Lucy, van der Lubbe, Joan E. M., Bakkers, Mark J. G., Hardenberg, Gijs, Wegmann, Frank, Zuijdgeest, David, de Wilde, Adriaan H., Koornneef, Annemart, Verwilligen, Annemiek, van Manen, Danielle, Kwaks, Ted, Vogels, Ronald, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Li, Zhenfeng, Barouch, Dan H., Vellinga, Jort, Langedijk, Johannes P. M., Zahn, Roland C., Custers, Jerome, Schuitemaker, Hanneke
Published in npj vaccines (28.09.2020)
Published in npj vaccines (28.09.2020)
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CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits
Koornneef, Annemart, Vanshylla, Kanika, Hardenberg, Gijs, Rutten, Lucy, Strokappe, Nika M, Tolboom, Jeroen, Vreugdenhil, Jessica, Boer, Karin Feddes-de, Perkasa, Aditya, Blokland, Sven, Burger, Judith A, Huang, Wei-Chiao, Lovell, Jonathan F, van Manen, Danielle, Sanders, Rogier W, Zahn, Roland C, Schuitemaker, Hanneke, Langedijk, Johannes P M, Wegmann, Frank
Published in Nature communications (11.04.2024)
Published in Nature communications (11.04.2024)
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Booster with Ad26.COV2.S or Omicron-adapted vaccine enhanced immunity and efficacy against SARS-CoV-2 Omicron in macaques
Solforosi, Laura, Costes, Lea M M, Tolboom, Jeroen T B M, McMahan, Katherine, Anioke, Tochi, Hope, David, Murdza, Tetyana, Sciacca, Michaela, Bouffard, Emily, Barrett, Julia, Wu, Cindy, Hachmann, Nicole, Miller, Jessica, Yu, Jingyou, He, Xuan, Jacob-Dolan, Catherine, Huber, Sietske K Rosendahl, Dekking, Liesbeth, Chamanza, Ronnie, Choi, Ying, Boer, Karin Feddes-de, Barouch, Dan H, Schuitemaker, Hanneke, Zahn, Roland C, Wegmann, Frank
Published in Nature communications (07.04.2023)
Published in Nature communications (07.04.2023)
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Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens
Sheppard, Neil C, Brinckmann, Sarah A, Gartlan, Kate H, Puthia, Manoj, Svanborg, Catharina, Krashias, George, Eisenbarth, Stephanie C, Flavell, Richard A, Sattentau, Quentin J, Wegmann, Frank
Published in International immunology (01.10.2014)
Published in International immunology (01.10.2014)
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ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability
Wegmann, Frank, Petri, Björn, Khandoga, Alexander Georg, Moser, Christian, Khandoga, Andrej, Volkery, Stefan, Li, Hang, Nasdala, Ines, Brandau, Oliver, Fässler, Reinhard, Butz, Stefan, Krombach, Fritz, Vestweber, Dietmar
Published in The Journal of experimental medicine (10.07.2006)
Published in The Journal of experimental medicine (10.07.2006)
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The Carbomer-Lecithin Adjuvant Adjuplex Has Potent Immunoactivating Properties and Elicits Protective Adaptive Immunity against Influenza Virus Challenge in Mice
Wegmann, Frank, Moghaddam, Amin E, Schiffner, Torben, Gartlan, Kate H, Powell, Timothy J, Russell, Rebecca A, Baart, Matthijs, Carrow, Emily W, Sattentau, Quentin J
Published in Clinical and vaccine immunology (01.09.2015)
Published in Clinical and vaccine immunology (01.09.2015)
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The Biodistribution of the Spike Protein after Ad26.COV2.S Vaccination Is Unlikely to Play a Role in Vaccine-Induced Immune Thrombotic Thrombocytopenia
Marquez-Martinez, Sonia, Khan, Selina, Lubbe, Joan van der, Solforosi, Laura, Costes, Lea M M, Choi, Ying, Boedhoe, Satish, Verslegers, Mieke, Heerden, Marjolein van, Roosen, Wendy, Jonghe, Sandra De, Kristyanto, Hendy, Rezelj, Veronica, Hendriks, Jenny, Serroyen, Jan, Tolboom, Jeroen, Wegmann, Frank, Zahn, Roland C
Published in Vaccines (Basel) (01.05.2024)
Published in Vaccines (Basel) (01.05.2024)
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Intravenous Administration of Ad26.COV2.S Does Not Induce Thrombocytopenia or Thrombotic Events or Affect SARS-CoV-2 Spike Protein Bioavailability in Blood Compared with Intramuscular Vaccination in Rabbits
Khan, Selina, Marquez-Martinez, Sonia, Erkens, Tim, de Wilde, Adriaan, Costes, Lea M M, Vinken, Petra, De Jonghe, Sandra, Roosen, Wendy, Talia, Chiara, Chamanza, Ronnie, Serroyen, Jan, Tolboom, Jeroen, Zahn, Roland C, Wegmann, Frank
Published in Vaccines (Basel) (30.11.2023)
Published in Vaccines (Basel) (30.11.2023)
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Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants
Lai, Rachel P J, Seaman, Michael S, Tonks, Paul, Wegmann, Frank, Seilly, David J, Frost, Simon D W, LaBranche, Celia C, Montefiori, David C, Dey, Antu K, Srivastava, Indresh K, Sattentau, Quentin, Barnett, Susan W, Heeney, Jonathan L
Published in PloS one (11.04.2012)
Published in PloS one (11.04.2012)
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Durability and expansion of neutralizing antibody breadth following Ad26.COV2.S vaccination of mice
Mahrokhian, Shant H, Tostanoski, Lisa H, Jacob-Dolan, Catherine, Zahn, Roland C, Wegmann, Frank, McMahan, Katherine, Yu, Jingyou, Gebre, Makda S, Bondzie, Esther A, Wan, Huahua, Powers, Olivia, Ye, Tianyi, Barrett, Julia, Schuitemaker, Hanneke, Barouch, Dan H
Published in npj vaccines (23.02.2022)
Published in npj vaccines (23.02.2022)
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Coxsackievirus-adenovirus receptor (CAR) is essential for early embryonic cardiac development
Dorner, Armin A, Wegmann, Frank, Butz, Stefan, Wolburg-Buchholz, Karen, Wolburg, Hartwig, Mack, Andreas, Nasdala, Ines, August, Benjamin, Westermann, Jůrgen, Rathjen, Fritz G, Vestweber, Dietmar
Published in Journal of cell science (01.08.2005)
Published in Journal of cell science (01.08.2005)
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Therapeutic efficacy of an Ad26/MVA vaccine with SIV gp140 protein and vesatolimod in ART-suppressed rhesus macaques
Ventura, John D, Nkolola, Joseph P, Chandrashekar, Abishek, Borducchi, Erica N, Liu, Jinyan, Mercado, Noe B, Hope, David L, Giffin, Victoria M, McMahan, Katherine, Geleziunas, Romas, Murry, Jeffrey P, Yang, Yunling, Lewis, Mark G, Pau, Maria G, Wegmann, Frank, Schuitemaker, Hanneke, Fray, Emily J, Kumar, Mithra R, Siliciano, Janet D, Siliciano, Robert F, Robb, Merlin L, Michael, Nelson L, Barouch, Dan H
Published in npj vaccines (18.05.2022)
Published in npj vaccines (18.05.2022)
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A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment
Wegmann, Frank, Krashias, George, Lühn, Kerstin, Laamanen, Karoliina, Vieira, Sueli, Jeffs, Simon A, Shattock, Robin J, Sattentau, Quentin J
Published in PloS one (06.01.2011)
Published in PloS one (06.01.2011)
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Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques
Mercado, Noe B, Zahn, Roland, Wegmann, Frank, Loos, Carolin, Chandrashekar, Abishek, Yu, Jingyou, Liu, Jinyan, Peter, Lauren, McMahan, Katherine, Tostanoski, Lisa H, He, Xuan, Martinez, David R, Rutten, Lucy, Bos, Rinke, van Manen, Danielle, Vellinga, Jort, Custers, Jerome, Langedijk, Johannes P, Kwaks, Ted, Bakkers, Mark J G, Zuijdgeest, David, Rosendahl Huber, Sietske K, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S, Feldman, Jared, Hauser, Blake M, Caradonna, Timothy M, Bondzie, Esther A, Dagotto, Gabriel, Gebre, Makda S, Hoffman, Emily, Jacob-Dolan, Catherine, Kirilova, Marinela, Li, Zhenfeng, Lin, Zijin, Mahrokhian, Shant H, Maxfield, Lori F, Nampanya, Felix, Nityanandam, Ramya, Nkolola, Joseph P, Patel, Shivani, Ventura, John D, Verrington, Kaylee, Wan, Huahua, Pessaint, Laurent, Van Ry, Alex, Blade, Kelvin, Strasbaugh, Amanda, Cabus, Mehtap, Brown, Renita, Cook, Anthony, Zouantchangadou, Serge, Teow, Elyse, Andersen, Hanne, Lewis, Mark G, Cai, Yongfei, Chen, Bing, Schmidt, Aaron G, Reeves, R Keith, Baric, Ralph S, Lauffenburger, Douglas A, Alter, Galit, Stoffels, Paul, Mammen, Mathai, Van Hoof, Johan, Schuitemaker, Hanneke, Barouch, Dan H
Published in Nature (London) (22.10.2020)
Published in Nature (London) (22.10.2020)
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SARS-CoV-2 infection protects against rechallenge in rhesus macaques
Chandrashekar, Abishek, Liu, Jinyan, Martinot, Amanda J, McMahan, Katherine, Mercado, Noe B, Peter, Lauren, Tostanoski, Lisa H, Yu, Jingyou, Maliga, Zoltan, Nekorchuk, Michael, Busman-Sahay, Kathleen, Terry, Margaret, Wrijil, Linda M, Ducat, Sarah, Martinez, David R, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S, Slein, Matthew D, Pessaint, Laurent, Van Ry, Alex, Greenhouse, Jack, Taylor, Tammy, Blade, Kelvin, Cook, Anthony, Finneyfrock, Brad, Brown, Renita, Teow, Elyse, Velasco, Jason, Zahn, Roland, Wegmann, Frank, Abbink, Peter, Bondzie, Esther A, Dagotto, Gabriel, Gebre, Makda S, He, Xuan, Jacob-Dolan, Catherine, Kordana, Nicole, Li, Zhenfeng, Lifton, Michelle A, Mahrokhian, Shant H, Maxfield, Lori F, Nityanandam, Ramya, Nkolola, Joseph P, Schmidt, Aaron G, Miller, Andrew D, Baric, Ralph S, Alter, Galit, Sorger, Peter K, Estes, Jacob D, Andersen, Hanne, Lewis, Mark G, Barouch, Dan H
Published in Science (14.08.2020)
Published in Science (14.08.2020)
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DNA vaccine protection against SARS-CoV-2 in rhesus macaques
Yu, Jingyou, Tostanoski, Lisa H, Peter, Lauren, Mercado, Noe B, McMahan, Katherine, Mahrokhian, Shant H, Nkolola, Joseph P, Liu, Jinyan, Li, Zhenfeng, Chandrashekar, Abishek, Martinez, David R, Loos, Carolin, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S, Slein, Matthew D, Chen, Yuezhou, Zuiani, Adam, Lelis, Felipe J N, Travers, Meghan, Habibi, Shaghayegh, Pessaint, Laurent, Van Ry, Alex, Blade, Kelvin, Brown, Renita, Cook, Anthony, Finneyfrock, Brad, Dodson, Alan, Teow, Elyse, Velasco, Jason, Zahn, Roland, Wegmann, Frank, Bondzie, Esther A, Dagotto, Gabriel, Gebre, Makda S, He, Xuan, Jacob-Dolan, Catherine, Kirilova, Marinela, Kordana, Nicole, Lin, Zijin, Maxfield, Lori F, Nampanya, Felix, Nityanandam, Ramya, Ventura, John D, Wan, Huahua, Cai, Yongfei, Chen, Bing, Schmidt, Aaron G, Wesemann, Duane R, Baric, Ralph S, Alter, Galit, Andersen, Hanne, Lewis, Mark G, Barouch, Dan H
Published in Science (14.08.2020)
Published in Science (14.08.2020)
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Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters
Tostanoski, Lisa H, Wegmann, Frank, Martinot, Amanda J, Loos, Carolin, McMahan, Katherine, Mercado, Noe B, Yu, Jingyou, Chan, Chi N, Bondoc, Stephen, Starke, Carly E, Nekorchuk, Michael, Busman-Sahay, Kathleen, Piedra-Mora, Cesar, Wrijil, Linda M, Ducat, Sarah, Custers, Jerome, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S, Feldman, Jared, Hauser, Blake M, Caradonna, Timothy M, Bondzie, Esther A, Dagotto, Gabriel, Gebre, Makda S, Jacob-Dolan, Catherine, Lin, Zijin, Mahrokhian, Shant H, Nampanya, Felix, Nityanandam, Ramya, Pessaint, Laurent, Porto, Maciel, Ali, Vaneesha, Benetiene, Dalia, Tevi, Komlan, Andersen, Hanne, Lewis, Mark G, Schmidt, Aaron G, Lauffenburger, Douglas A, Alter, Galit, Estes, Jacob D, Schuitemaker, Hanneke, Zahn, Roland, Barouch, Dan H
Published in Nature medicine (01.11.2020)
Published in Nature medicine (01.11.2020)
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Coronavirus-Specific Antibody Cross Reactivity in Rhesus Macaques Following SARS-CoV-2 Vaccination and Infection
Jacob-Dolan, Catherine, Feldman, Jared, McMahan, Katherine, Yu, Jingyou, Zahn, Roland, Wegmann, Frank, Schuitemaker, Hanneke, Schmidt, Aaron G, Barouch, Dan H
Published in Journal of virology (10.05.2021)
Published in Journal of virology (10.05.2021)
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Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques
He, Xuan, Chandrashekar, Abishek, Zahn, Roland, Wegmann, Frank, Yu, Jingyou, Mercado, Noe B., McMahan, Katherine, Martinot, Amanda J., Piedra-Mora, Cesar, Beecy, Sidney, Ducat, Sarah, Chamanza, Ronnie, Huber, Sietske Rosendahl, van Heerden, Marjolein, van der Fits, Leslie, Borducchi, Erica N., Lifton, Michelle, Liu, Jinyan, Nampanya, Felix, Patel, Shivani, Peter, Lauren, Tostanoski, Lisa H., Pessaint, Laurent, Van Ry, Alex, Finneyfrock, Brad, Velasco, Jason, Teow, Elyse, Brown, Renita, Cook, Anthony, Andersen, Hanne, Lewis, Mark G., Schuitemaker, Hanneke, Barouch, Dan H.
Published in Cell (24.06.2021)
Published in Cell (24.06.2021)
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