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Reich, Siegfried H, Sprengeler, Paul A, Chiang, Gary G, Appleman, James R, Chen, Joan, Clarine, Jeff, Eam, Boreth, Ernst, Justin T, Han, Qing, Goel, Vikas K, Han, Edward Z. R, Huang, Vera, Hung, Ivy N. J, Jemison, Adrianna, Jessen, Katti A, Molter, Jolene, Murphy, Douglas, Neal, Melissa, Parker, Gregory S, Shaghafi, Michael, Sperry, Samuel, Staunton, Jocelyn, Stumpf, Craig R, Thompson, Peggy A, Tran, Chinh, Webber, Stephen E, Wegerski, Christopher J, Zheng, Hong, Webster, Kevin R
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Published in Journal of medicinal chemistry (26.04.2018)
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Thomas, Huw D, Calabrese, Christopher R, Batey, Michael A, Canan, Stacie, Hostomsky, Zdenek, Kyle, Suzanne, Maegley, Karen A, Newell, David R, Skalitzky, Donald, Wang, Lan-Zhen, Webber, Stephen E, Curtin, Nicola J
Published in Molecular cancer therapeutics (01.03.2007)
Published in Molecular cancer therapeutics (01.03.2007)
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Transcription inactivation through local refolding of the RNA polymerase structure
BELOGUROV, Georgiy A, VASSYLYEVA, Marina N, VASSYLYEV, Dmitry G, SEVOSTYANOVA, Anastasiya, APPLEMAN, James R, XIANG, Alan X, LIRA, Ricardo, WEBBER, Stephen E, KLYUYEV, Sergiy, NUDLER, Evgeny, ARTSIMOVITCH, Irina
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Water-in-Carbon Dioxide Microemulsions with Methylated Branched Hydrocarbon Surfactants
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Zhou, Yuefen, Gregor, Vlad E., Ayida, Benjamin K., Winters, Geoffrey C., Sun, Zhongxiang, Murphy, Douglas, Haley, Greg, Bailey, Dwight, Froelich, Jamie M., Fish, Sarah, Webber, Stephen E., Hermann, Thomas, Wall, Daniel
Published in Bioorganic & medicinal chemistry letters (01.03.2007)
Published in Bioorganic & medicinal chemistry letters (01.03.2007)
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Anticancer chemosensitization and radiosensitization by the novel Poly(ADP-ribose) polymerase-1 inhibitor AG14361
CALABRESE, Christopher R, ALMASSY, Robert, LI, Jianke, MAEGLEY, Karen, NEWELL, David R, NOTARIANNI, Elena, STRATFORD, Ian J, SKALITZKY, Donald, THOMAS, Huw D, WANG, Ian-Zhen, WEBBER, Stephen E, WILLIAMS, Kaye J, BARTON, Stephanie, CURTIN, Nicola J, BATEY, Michael A, CALVERT, A. Hilary, CANAN-KOCH, Stacie, DURKACZ, Barbara W, HOSTOMSKY, Zdenek, KUMPF, Robert A, KYLE, Suzanne
Published in JNCI : Journal of the National Cancer Institute (07.01.2004)
Published in JNCI : Journal of the National Cancer Institute (07.01.2004)
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Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells
CURTIN, Nicola J, WANG, Lan-Zhen, NEWELL, David R, YIAKOUVAKI, Anthie, KYLE, Suzanne, ARRIS, Christine A, CANAN-KOCH, Stacie, WEBBER, Stephen E, DURKACZ, Barbara W, CALVERT, Hilary A, HOSTOMSKY, Zdenek
Published in Clinical cancer research (01.02.2004)
Published in Clinical cancer research (01.02.2004)
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Tang, Tingji, Herrmann, Andreas, Peneva, Kalina, Müllen, Klaus, Webber, Stephen E
Published in Langmuir (10.04.2007)
Published in Langmuir (10.04.2007)
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Therapeutic Benefit of a Dissociated Glucocorticoid and the Relevance of In Vitro Separation of Transrepression from Transactivation Activity
Belvisi, Maria G, Wicks, Sharon L, Battram, Clifford H, Bottoms, Stephen E. W, Redford, Jane E, Woodman, Paul, Brown, Thomas J, Webber, Stephen E, Foster, Martyn L
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Tricyclic Benzimidazoles as Potent Poly(ADP-ribose) Polymerase-1 Inhibitors
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Published in Journal of medicinal chemistry (16.01.2003)
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Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase
RUEBSAM, Frank, MURPHY, Douglas E, BLAZEL, Julie K, SUN HEE KIM, YUEFEN ZHOU, QING HAN, KISSINGER, Charles R, WEBBER, Stephen E, SHOWALTER, Richard E, SHAH, Amit M, TSAN, Mei, PATEL, Rupal A, TRAN, Chinh V, THOMPSON, Peggy A, LEBRUN, Laurie A, HOU, Huiying J, KAMRAN, Ruhi, SERGEEVA, Maria V, BARTKOWSKI, Darian M, NOLAN, Thomas G, NORRIS, Daniel A, KHANDURINA, Julia, BROOKS, Jennifer, LI, Lian-Sheng, OKAMOTO, Ellen, KIRKOVSKY, Leo, JINGJING ZHAO, DRAGOVICH, Peter S, MCGUIRE, Helen M, XIANG, Alan X, ZHONGXIANG SUN, AYIDA, Benjamin K
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
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Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity: Design, Synthesis, and X-ray Cocrystal Structure
Canan Koch, Stacie S, Thoresen, Lars H, Tikhe, Jayashree G, Maegley, Karen A, Almassy, Robert J, Li, Jianke, Yu, Xiao-Hong, Zook, Scott E, Kumpf, Robert A, Zhang, Cathy, Boritzki, Theodore J, Mansour, Rena N, Zhang, Kanyin E, Ekker, Anne, Calabrese, Chris R, Curtin, Nicola J, Kyle, Suzanne, Thomas, Huw D, Wang, Lan-Zhen, Calvert, A. Hilary, Golding, Bernard T, Griffin, Roger J, Newell, David R, Webber, Stephen E, Hostomsky, Zdenek
Published in Journal of medicinal chemistry (07.11.2002)
Published in Journal of medicinal chemistry (07.11.2002)
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Preclinical Profile of Ciclesonide, a Novel Corticosteroid for the Treatment of Asthma
Belvisi, Maria G, Bundschuh, Daniela S, Stoeck, Michael, Wicks, Sharon, Underwood, Stephen, Battram, Clifford H, Haddad, El-Bdaoui, Webber, Stephen E, Foster, Martyn L
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Novel HCV NS5B polymerase inhibitors derived from 4-(1',1' -dioxo-1' 4'-dihydro-1 λ6-benzoll 1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: Exploration of 7'-substitution of benzothiadiazine
YUEFEN ZHOU, WEBBER, Stephen E, SHOWALTER, Richard E, PATEL, Rupal, BIN LI, QIANG ZHAO, QING HAN, HERMANN, Thomas, KISSINGER, Charles R, LEBRUN, Laurie, SERGEEVA, Maria V, KIRKOVSKY, Leo, MURPHY, Douglas E, LI, Lian-Sheng, DRAGOVICH, Peter S, TRAN, Chinh V, ZHONGXIANG SUN, RUEBSAM, Frank, SHAH, Amit M, TSAN, Mei
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
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Pyrrolo[1,2- b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase
Ruebsam, Frank, Webber, Stephen E., Tran, Martin T., Tran, Chinh V., Murphy, Douglas E., Zhao, Jingjing, Dragovich, Peter S., Kim, Sun Hee, Li, Lian-Sheng, Zhou, Yuefen, Han, Qing, Kissinger, Charles R., Showalter, Richard E., Lardy, Matthew, Shah, Amit M., Tsan, Mei, Patel, Rupal, LeBrun, Laurie A., Kamran, Ruhi, Sergeeva, Maria V., Bartkowski, Darian M., Nolan, Thomas G., Norris, Daniel A., Kirkovsky, Leo
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Syntheses of novel myxopyronin B analogs as potential inhibitors of bacterial RNA polymerase
Lira, Ricardo, Xiang, Alan X., Doundoulakis, Thomas, Biller, William T., Agrios, Konstantinos A., Simonsen, Klaus B., Webber, Stephen E., Sisson, Wes, Aust, Robert M., Shah, Amit M., Showalter, Richard E., Banh, Virginia N., Steffy, Kevin R., Appleman, James R.
Published in Bioorganic & medicinal chemistry letters (15.12.2007)
Published in Bioorganic & medicinal chemistry letters (15.12.2007)
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Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 3: Further optimization of the 2-, 6-, and 7'-substituents and initial pharmacokinetic assessments
Li, Lian-Sheng, Zhou, Yuefen, Murphy, Douglas E, Stankovic, Nebojsa, Zhao, Jingjing, Dragovich, Peter S, Bertolini, Thomas, Sun, Zhongxiang, Ayida, Benjamin, Tran, Chinh V, Ruebsam, Frank, Webber, Stephen E, Shah, Amit M, Tsan, Mei, Showalter, Richard E, Patel, Rupal, Lebrun, Laurie A, Bartkowski, Darian M, Nolan, Thomas G, Norris, Daniel A, Kamran, Ruhi, Brooks, Jennifer, Sergeeva, Maria V, Kirkovsky, Leo, Zhao, Qiang, Kissinger, Charles R
Published in Bioorganic & medicinal chemistry letters (01.06.2008)
Published in Bioorganic & medicinal chemistry letters (01.06.2008)
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