Genetic variability in the regulation of gene expression in ten regions of the human brain
Ramasamy, Adaikalavan, Trabzuni, Daniah, Guelfi, Sebastian, Varghese, Vibin, Smith, Colin, Walker, Robert, De, Tisham, Coin, Lachlan, de Silva, Rohan, Cookson, Mark R, Singleton, Andrew B, Hardy, John, Ryten, Mina, Weale, Michael E
Published in Nature neuroscience (01.10.2014)
Published in Nature neuroscience (01.10.2014)
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Widespread sex differences in gene expression and splicing in the adult human brain
Trabzuni, Daniah, Ramasamy, Adaikalavan, Imran, Sabaena, Walker, Robert, Smith, Colin, Weale, Michael E., Hardy, John, Ryten, Mina
Published in Nature communications (22.11.2013)
Published in Nature communications (22.11.2013)
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Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease
Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A, Chaffin, Mark, Horner, Steven, McMillan, Brian J, Leed, Alison, Weale, Michael E, Spencer, Chris C A, Aguet, François, Segrè, Ayellet V, Ardlie, Kristin G, Khera, Amit V, Kaushik, Virendar K, Natarajan, Pradeep, Kathiresan, Sekar
Published in Nature genetics (01.09.2017)
Published in Nature genetics (01.09.2017)
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Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies
Trabzuni, Daniah, Ryten, Mina, Walker, Robert, Smith, Colin, Imran, Sabaena, Ramasamy, Adaikalavan, Weale, Michael E., Hardy, John
Published in Journal of neurochemistry (01.10.2011)
Published in Journal of neurochemistry (01.10.2011)
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Gene expression changes with age in skin, adipose tissue, blood and brain
Glass, Daniel, Viñuela, Ana, Davies, Matthew N, Ramasamy, Adaikalavan, Parts, Leopold, Knowles, David, Brown, Andrew A, Hedman, Asa K, Small, Kerrin S, Buil, Alfonso, Grundberg, Elin, Nica, Alexandra C, Di Meglio, Paola, Nestle, Frank O, Ryten, Mina, Durbin, Richard, McCarthy, Mark I, Deloukas, Panagiotis, Dermitzakis, Emmanouil T, Weale, Michael E, Bataille, Veronique, Spector, Tim D
Published in Genome Biology (26.07.2013)
Published in Genome Biology (26.07.2013)
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An additional k-means clustering step improves the biological features of WGCNA gene co-expression networks
Botía, Juan A, Vandrovcova, Jana, Forabosco, Paola, Guelfi, Sebastian, D'Sa, Karishma, Hardy, John, Lewis, Cathryn M, Ryten, Mina, Weale, Michael E
Published in BMC systems biology (12.04.2017)
Published in BMC systems biology (12.04.2017)
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Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy
Guelfi, Sebastian, Botia, Juan A, Thom, Maria, Ramasamy, Adaikalavan, Perona, Marina, Stanyer, Lee, Martinian, Lillian, Trabzuni, Daniah, Smith, Colin, Walker, Robert, Ryten, Mina, Reimers, Mark, Weale, Michael E, Hardy, John, Matarin, Mar
Published in Brain (London, England : 1878) (01.06.2019)
Published in Brain (London, England : 1878) (01.06.2019)
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Insights into TREM2 biology by network analysis of human brain gene expression data
Forabosco, Paola, Ramasamy, Adaikalavan, Trabzuni, Daniah, Walker, Robert, Smith, Colin, Bras, Jose, Levine, Adam P, Hardy, John, Pocock, Jennifer M, Guerreiro, Rita, Weale, Michael E, Ryten, Mina
Published in Neurobiology of aging (01.12.2013)
Published in Neurobiology of aging (01.12.2013)
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Natural selection on EPAS1 (HIF2α) associated with low hemoglobin concentration in Tibetan highlanders
Beall, Cynthia M, Cavalleri, Gianpiero L, Deng, Libin, Elston, Robert C, Gao, Yang, Knight, Jo, Li, Chaohua, Li, Jiang Chuan, Liang, Yu, McCormack, Mark, Montgomery, Hugh E, Pan, Hao, Robbins, Peter A, Shianna, Kevin V, Tam, Siu Cheung, Tsering, Ngodrop, Veeramah, Krishna R, Wang, Wei, Wangdui, Puchung, Weale, Michael E, Xu, Yaomin, Xu, Zhe, Yang, Ling, Zaman, M. Justin, Zeng, Changqing, Zhang, Li, Zhang, Xianglong, Zhaxi, Pingcuo, Zheng, Yong Tang
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2010)
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Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries
Weale, Michael E., Riveros-Mckay, Fernando, Selzam, Saskia, Seth, Priyanka, Moore, Rachel, Tarran, William A., Gradovich, Eva, Giner-Delgado, Carla, Palmer, Duncan, Wells, Daniel, Saffari, Ayden, Sivley, R. Michael, Lachapelle, Alexander S., Wand, Hannah, Clarke, Shoa L., Knowles, Joshua W., O'Sullivan, Jack W., Ashley, Euan A., McVean, Gil, Plagnol, Vincent, Donnelly, Peter
Published in The American journal of cardiology (01.06.2021)
Published in The American journal of cardiology (01.06.2021)
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A systematic evaluation of the performance and properties of the UK Biobank Polygenic Risk Score (PRS) Release
Thompson, Deborah J, Wells, Daniel, Selzam, Saskia, Peneva, Iliana, Moore, Rachel, Sharp, Kevin, Tarran, William A, Beard, Edward J, Riveros-Mckay, Fernando, Giner-Delgado, Carla, Palmer, Duncan, Seth, Priyanka, Harrison, James, Futema, Marta, McVean, Gil, Plagnol, Vincent, Donnelly, Peter, Weale, Michael E
Published in PloS one (18.09.2024)
Published in PloS one (18.09.2024)
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MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
TRABZUNI, Daniah, WRAY, Selina, AREPALLI, Sampath, SINGLETON, Andrew B, COOKSON, Mark R, PITTMAN, Alan M, DE SILVA, Rohan, WEALE, Michael E, HARDY, John, RYTEN, Mina, VANDROVCOVA, Jana, RAMASAMY, Adaikalavan, WALKER, Robert, SMITH, Colin, LUK, Connie, RAPHAEL GIBBS, J, DILLMAN, Allissa, HERNANDEZ, Dena G
Published in Human molecular genetics (15.09.2012)
Published in Human molecular genetics (15.09.2012)
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Recursive splicing in long vertebrate genes
Sibley, Christopher R., Emmett, Warren, Blazquez, Lorea, Faro, Ana, Haberman, Nejc, Briese, Michael, Trabzuni, Daniah, Ryten, Mina, Weale, Michael E., Hardy, John, Modic, Miha, Curk, Tomaž, Wilson, Stephen W., Plagnol, Vincent, Ule, Jernej
Published in Nature (London) (21.05.2015)
Published in Nature (London) (21.05.2015)
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Genetic signatures reveal high-altitude adaptation in a set of ethiopian populations
Huerta-Sánchez, Emilia, Degiorgio, Michael, Pagani, Luca, Tarekegn, Ayele, Ekong, Rosemary, Antao, Tiago, Cardona, Alexia, Montgomery, Hugh E, Cavalleri, Gianpiero L, Robbins, Peter A, Weale, Michael E, Bradman, Neil, Bekele, Endashaw, Kivisild, Toomas, Tyler-Smith, Chris, Nielsen, Rasmus
Published in Molecular biology and evolution (01.08.2013)
Published in Molecular biology and evolution (01.08.2013)
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A genome-wide investigation of SNPs and CNVs in schizophrenia
Need, Anna C, Ge, Dongliang, Weale, Michael E, Maia, Jessica, Feng, Sheng, Heinzen, Erin L, Shianna, Kevin V, Yoon, Woohyun, Kasperaviciūte, Dalia, Gennarelli, Massimo, Strittmatter, Warren J, Bonvicini, Cristian, Rossi, Giuseppe, Jayathilake, Karu, Cola, Philip A, McEvoy, Joseph P, Keefe, Richard S E, Fisher, Elizabeth M C, St Jean, Pamela L, Giegling, Ina, Hartmann, Annette M, Möller, Hans-Jürgen, Ruppert, Andreas, Fraser, Gillian, Crombie, Caroline, Middleton, Lefkos T, St Clair, David, Roses, Allen D, Muglia, Pierandrea, Francks, Clyde, Rujescu, Dan, Meltzer, Herbert Y, Goldstein, David B
Published in PLoS genetics (01.02.2009)
Published in PLoS genetics (01.02.2009)
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Long-Range LD Can Confound Genome Scans in Admixed Populations
Price, Alkes L., Weale, Michael E., Patterson, Nick, Myers, Simon R., Need, Anna C., Shianna, Kevin V., Ge, Dongliang, Rotter, Jerome I., Torres, Esther, Taylor, Kent D., Goldstein, David B., Reich, David
Published in American journal of human genetics (01.07.2008)
Published in American journal of human genetics (01.07.2008)
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