Functional significance of the platelet immune receptors GPVI and CLEC-2
Rayes, Julie, Watson, Steve P, Nieswandt, Bernhard
Published in The Journal of clinical investigation (02.01.2019)
Published in The Journal of clinical investigation (02.01.2019)
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Journal Article
Fibrin activates GPVI in human and mouse platelets
Alshehri, Osama M., Hughes, Craig E., Montague, Samantha, Watson, Stephanie K., Frampton, Jon, Bender, Markus, Watson, Steve P.
Published in Blood (24.09.2015)
Published in Blood (24.09.2015)
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Journal Article
The podoplanin-CLEC-2 axis inhibits inflammation in sepsis
Rayes, Julie, Lax, Siân, Wichaiyo, Surasak, Watson, Stephanie K, Di, Ying, Lombard, Stephanie, Grygielska, Beata, Smith, Stuart W, Skordilis, Kassiani, Watson, Steve P
Published in Nature communications (21.12.2017)
Published in Nature communications (21.12.2017)
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Journal Article
Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2
Bourne, Joshua H, Colicchia, Martina, Di, Ying, Martin, Eleyna, Slater, Alexander, Roumenina, Lubka T, Dimitrov, Jordan D, Watson, Steve P, Rayes, Julie
Published in Haematologica (Roma) (01.02.2021)
Published in Haematologica (Roma) (01.02.2021)
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Journal Article
The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure
Chauhan, Abhishek, Sheriff, Lozan, Hussain, Mohammed T, Webb, Gwilym J, Patten, Daniel A, Shepherd, Emma L, Shaw, Robert, Weston, Christopher J, Haldar, Debashis, Bourke, Samuel, Bhandari, Rajan, Watson, Stephanie, Adams, David H, Watson, Steve P, Lalor, Patricia F
Published in Nature communications (22.04.2020)
Published in Nature communications (22.04.2020)
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Journal Article
Immobilized fibrinogen activates human platelets through glycoprotein VI
Mangin, Pierre H, Onselaer, Marie-Blanche, Receveur, Nicolas, Le Lay, Nicolas, Hardy, Alexander T, Wilson, Clare, Sanchez, Ximena, Loyau, Stéphane, Dupuis, Arnaud, Babar, Amir K, Miller, Jeanette Lc, Philippou, Helen, Hughes, Craig E, Herr, Andrew B, Ariëns, Robert As, Mezzano, Diego, Jandrot-Perrus, Martine, Gachet, Christian, Watson, Steve P
Published in Haematologica (Roma) (01.05.2018)
Published in Haematologica (Roma) (01.05.2018)
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Journal Article
Combined In Vivo Depletion of Glycoprotein VI and C-Type Lectin-Like Receptor 2 Severely Compromises Hemostasis and Abrogates Arterial Thrombosis in Mice
Bender, Markus, May, Frauke, Lorenz, Viola, Thielmann, Ina, Hagedorn, Ina, Finney, Brenda A, Vögtle, Timo, Remer, Katharina, Braun, Attila, Bösl, Michael, Watson, Steve P, Nieswandt, Bernhard
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2013)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2013)
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Journal Article
Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation
Mazharian, Alexandra, Ghevaert, Cedric, Zhang, Lin, Massberg, Steffen, Watson, Steve P.
Published in Blood (12.05.2011)
Published in Blood (12.05.2011)
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Journal Article
Introducing high-throughput sequencing into mainstream genetic diagnosis practice in inherited platelet disorders
Bastida, José M, Lozano, María L, Benito, Rocío, Janusz, Kamila, Palma-Barqueros, Verónica, Del Rey, Mónica, Hernández-Sánchez, Jesús M, Riesco, Susana, Bermejo, Nuria, González-García, Hermenegildo, Rodriguez-Alén, Agustín, Aguilar, Carlos, Sevivas, Teresa, López-Fernández, María F, Marneth, Anna E, van der Reijden, Bert A, Morgan, Neil V, Watson, Steve P, Vicente, Vicente, Hernández-Rivas, Jesús M, Rivera, José, González-Porras, José R
Published in Haematologica (Roma) (01.01.2018)
Published in Haematologica (Roma) (01.01.2018)
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Journal Article
Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets
Hitchcock, Jessica R, Cook, Charlotte N, Bobat, Saeeda, Ross, Ewan A, Flores-Langarica, Adriana, Lowe, Kate L, Khan, Mahmood, Dominguez-Medina, C Coral, Lax, Sian, Carvalho-Gaspar, Manuela, Hubscher, Stefan, Rainger, G Ed, Cobbold, Mark, Buckley, Christopher D, Mitchell, Tim J, Mitchell, Andrea, Jones, Nick D, Van Rooijen, N, Kirchhofer, Daniel, Henderson, Ian R, Adams, David H, Watson, Steve P, Cunningham, Adam F
Published in The Journal of clinical investigation (01.12.2015)
Published in The Journal of clinical investigation (01.12.2015)
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Journal Article
Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases
Harbi, Maan H., Smith, Christopher W., Nicolson, Phillip L. R., Watson, Steve P., Thomas, Mark R.
Published in Platelets (Edinburgh) (02.01.2021)
Published in Platelets (Edinburgh) (02.01.2021)
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Journal Article
CLEC-2 expression is maintained on activated platelets and on platelet microparticles
Gitz, Eelo, Pollitt, Alice Y., Gitz-Francois, Jerney J., Alshehri, Osama, Mori, Jun, Montague, Samantha, Nash, Gerard B., Douglas, Michael R., Gardiner, Elizabeth E., Andrews, Robert K., Buckley, Christopher D., Harrison, Paul, Watson, Steve P.
Published in Blood (02.10.2014)
Published in Blood (02.10.2014)
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Journal Article
Low-dose Btk inhibitors selectively block platelet activation by CLEC-2
Nicolson, Phillip L R, Nock, Sophie H, Hinds, Joshua, Garcia-Quintanilla, Lourdes, Smith, Christopher W, Campos, Joana, Brill, Alexander, Pike, Jeremy A, Khan, Abdullah O, Poulter, Natalie S, Kavanagh, Diedre M, Watson, Stephanie, Watson, Callum N, Clifford, Hayley, Huissoon, Aarnoud P, Pollitt, Alice Y, Eble, Johannes A, Pratt, Guy, Watson, Steve P, Hughes, Craig E
Published in Haematologica (Roma) (01.01.2021)
Published in Haematologica (Roma) (01.01.2021)
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Journal Article
JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia
Hobbs, Catherine M., Manning, Harriet, Bennett, Cavan, Vasquez, Louella, Severin, Sonia, Brain, Lauren, Mazharian, Alexandra, Guerrero, Jose A., Li, Juan, Soranzo, Nicole, Green, Anthony R., Watson, Steve P., Ghevaert, Cedric
Published in Blood (28.11.2013)
Published in Blood (28.11.2013)
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Journal Article
Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation
Chimen, Myriam, Evryviadou, Aigli, Box, Clare L, Harrison, Matthew J, Hazeldine, Jon, Dib, Lea H, Kuravi, Sahithi J, Payne, Holly, Price, Joshua M J, Kavanagh, Dean, Iqbal, Asif J, Lax, Sian, Kalia, Neena, Brill, Alex, Thomas, Steve G, Belli, Antonio, Crombie, Nicholas, Adams, Rachel A, Evans, Shelley-Ann, Deckmyn, Hans, Lord, Janet M, Harrison, Paul, Watson, Steve P, Nash, Gerard B, Rainger, G Ed
Published in Haematologica (Roma) (01.05.2020)
Published in Haematologica (Roma) (01.05.2020)
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Journal Article
The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent
Rayes, Julie, Jadoui, Soumaya, Lax, Siân, Gros, Angèle, Wichaiyo, Surasak, Ollivier, Véronique, Denis, Cécile V, Ware, Jerry, Nieswandt, Bernhard, Jandrot-Perrus, Martine, Watson, Steve P, Ho-Tin-Noé, Benoît
Published in Haematologica (Roma) (01.06.2018)
Published in Haematologica (Roma) (01.06.2018)
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