Search Results - "WATANABE, KA" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

by Clark, Jeremy L, Hollecker, Laurent, Mason, J. Christian, Stuyver, Lieven J, Tharnish, Phillip M, Lostia, Stefania, McBrayer, Tamara R, Schinazi, Raymond F, Watanabe, Kyoichi A, Otto, Michael J, Furman, Phillip A, Stec, Wojciech J, Patterson, Steven E, Pankiewicz, Krzysztof W
Published in Journal of medicinal chemistry (25.08.2005)

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Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture

Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture

by STUYVER, Lieven J, WHITAKER, Tony, RACHAKONDA, Suguna, WATANABE, Kyoichi A, OTTO, Michael J, SCHINAZI, Raymond F, MCBRAYER, Tamara R, HERNANDEZ-SANTIAGO, Brenda I, LOSTIA, Stefania, THARNISH, Phillip M, RAMESH, Mangala, CHU, Chung K, JORDAN, Robert, JUNXING SHI
Published in Antimicrobial Agents and Chemotherapy (01.01.2003)

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Kinetic Mechanism of Damage Site Recognition and Uracil Flipping by Escherichia coli Uracil DNA Glycosylase

Kinetic Mechanism of Damage Site Recognition and Uracil Flipping by Escherichia coli Uracil DNA Glycosylase

by Stivers, James T, Pankiewicz, Krzysztof W, Watanabe, Kyoichi A
Published in Biochemistry (Easton) (19.01.1999)

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Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication

Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication

by Clark, Jeremy L., Mason, J. Christian, Hollecker, Laurent, Stuyver, Lieven J., Tharnish, Phillip M., McBrayer, Tamara R., Otto, Michael J., Furman, Phillip A., Schinazi, Raymond F., Watanabe, Kyoichi A.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)

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Targeted gene knockout mediated by triple helix forming oligonucleotides

Targeted gene knockout mediated by triple helix forming oligonucleotides

by Seidman, Michael M, Majumdar, Alokes, Khorlin, Alexander, Dyatkina, Natalia, Lin, F.-L. Michael, Powell, James, Liu, Jilan, Fei, Zhizhong, Khripine, Yuri, Watanabe, Kyoichi A, George, Jay, Glazer, Peter M
Published in Nature genetics (01.10.1998)

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Dynamics of Subgenomic Hepatitis C Virus Replicon RNA Levels in Huh-7 Cells after Exposure to Nucleoside Antimetabolites

Dynamics of Subgenomic Hepatitis C Virus Replicon RNA Levels in Huh-7 Cells after Exposure to Nucleoside Antimetabolites

by Stuyver, Lieven J, McBrayer, Tamara R, Tharnish, Phillip M, Hassan, Abdalla E A, Chu, Chung K, Pankiewicz, Krzysztof W, Watanabe, Kyochi A, Schinazi, Raymond F, Otto, Michael J
Published in Journal of Virology (01.10.2003)

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Inhibition of the Subgenomic Hepatitis C Virus Replicon in Huh-7 Cells by 2′-Deoxy-2′-Fluorocytidine

Inhibition of the Subgenomic Hepatitis C Virus Replicon in Huh-7 Cells by 2′-Deoxy-2′-Fluorocytidine

by Stuyver, Lieven J, McBrayer, Tamara R, Whitaker, Tony, Tharnish, Phillip M, Ramesh, Mangala, Lostia, Stefania, Cartee, Leanne, Shi, Junxing, Hobbs, Ann, Schinazi, Raymond F, Watanabe, Kyoichi A, Otto, Michael J
Published in Antimicrobial Agents and Chemotherapy (01.02.2004)

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Synthesis of N-3,5 '-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity

Synthesis of N-3,5 '-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity

by Wang, PY, Hollecker, L, Pankiewicz, KW, Patterson, SE, Whitaker, T, McBrayer, TR, Tharnish, PM, Sidwell, RW, Stuyver, LJ, Otto, MJ, Schinazi, RF, Watanabe, KA
Published in Journal of medicinal chemistry (18.11.2004)

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Imidazoleacetic Acid-Ribotide: An Endogenous Ligand That Stimulates Imidazol(in)e Receptors

Imidazoleacetic Acid-Ribotide: An Endogenous Ligand That Stimulates Imidazol(in)e Receptors

by Prell, George D., Martinelli, Giorgio P., Holstein, Gay R., Matulić-Adamić, Jasenka, Watanabe, Kyoichi A., Susan L. F. Chan, Morgan, Noel G., Haxhiu, Musa A., Ernsberger, Paul, Black, James W.
Published in Proceedings of the National Academy of Sciences - PNAS (14.09.2004)

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Synthesis and Structure−Activity Relationships of Novel Anti-hepatitis C Agents: N 3,5‘-Cyclo-4-(β-d-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one Derivatives

Synthesis and Structure−Activity Relationships of Novel Anti-hepatitis C Agents: N 3,5‘-Cyclo-4-(β-d-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one Derivatives

by Wang, Peiyuan, Du, Jinfa, Rachakonda, Suguna, Chun, Byoung-Kwon, Tharnish, Phillip M, Stuyver, Lieven J, Otto, Michael J, Schinazi, Raymond F, Watanabe, Kyoichi A
Published in Journal of medicinal chemistry (06.10.2005)

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Novel Mycophenolic Adenine Bis(phosphonate) Analogues As Potential Differentiation Agents against Human Leukemia

Novel Mycophenolic Adenine Bis(phosphonate) Analogues As Potential Differentiation Agents against Human Leukemia

by Pankiewicz, Krzysztof W, Lesiak-Watanabe, Krystyna B, Watanabe, Kyoichi A, Patterson, Steven E, Jayaram, Hiremagalur N, Yalowitz, Joel A, Miller, Michael D, Seidman, Michael, Majumdar, Alokes, Prehna, Gerd, Goldstein, Barry M
Published in Journal of medicinal chemistry (31.01.2002)

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Facile Preparation of α-Acyloxyacetaldehyde, a Versatile Intermediate in the Synthesis of Antiviral Nucleosides

Facile Preparation of α-Acyloxyacetaldehyde, a Versatile Intermediate in the Synthesis of Antiviral Nucleosides

by Du, Jinfa, Watanabe, Kyoichi A.
Published in Synthetic communications (31.12.2004)

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Synthesis of 5′,9-anhydro-3-(β- d-ribofuranosyl)xanthine, and 3,5′-anhydro-xanthosine as potential anti-hepatitis C virus agents

Synthesis of 5′,9-anhydro-3-(β- d-ribofuranosyl)xanthine, and 3,5′-anhydro-xanthosine as potential anti-hepatitis C virus agents

by Chun, Byoung-Kwon, Wang, Peiyuan, Hassan, Abdalla, Du, Jinfa, Tharnish, Phillip M., Stuyver, Lieven J., Otto, Michael J., Schinazi, Raymond F., Watanabe, Kyoichi A.
Published in Tetrahedron letters (18.04.2005)

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Heteronuclear NMR and Crystallographic Studies of Wild-Type and H187Q Escherichia coli Uracil DNA Glycosylase: Electrophilic Catalysis of Uracil Expulsion by a Neutral Histidine 187

Heteronuclear NMR and Crystallographic Studies of Wild-Type and H187Q Escherichia coli Uracil DNA Glycosylase: Electrophilic Catalysis of Uracil Expulsion by a Neutral Histidine 187

by Drohat, Alexander C, Xiao, Gaoyi, Tordova, Maria, Jagadeesh, Jaya, Pankiewicz, Krzysztof W, Watanabe, Kyoichi A, Gilliland, Gary L, Stivers, James T
Published in Biochemistry (Easton) (14.09.1999)

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Fialuridine and its Metabolites Inhibit DNA Polymerase γ at Sites of Multiple Adjacent Analog Incorporation, Decrease mtDNA Abundance, and Cause Mitochondrial Structural Defects in Cultured Hepatoblasts

Fialuridine and its Metabolites Inhibit DNA Polymerase γ at Sites of Multiple Adjacent Analog Incorporation, Decrease mtDNA Abundance, and Cause Mitochondrial Structural Defects in Cultured Hepatoblasts

by Lewis, William, Levine, Eric S., Griniuviene, Brone, Tankersley, Kevin O., Colacino, Joseph M., Sommadossi, Jean-Pierre, Watanabe, Kyoichi A., Perrino, Fred W.
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.1996)

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Synthesis and Structure-Activity Relationships of Novel Anti-hepatitis C Agents: N super(3),5'-Cyclo-4-( beta -D-ribofuranosyl)- vic-triazolo[4,5-b]pyridin-5-one Derivatives

Synthesis and Structure-Activity Relationships of Novel Anti-hepatitis C Agents: N super(3),5'-Cyclo-4-( beta -D-ribofuranosyl)- vic-triazolo[4,5-b]pyridin-5-one Derivatives

by Wang, P, Du, J, Rachakonda, S, Chun, B-K, Tharnish, P M, Stuyver, L J, Otto, MJ, Schinazi, R F, Watanabe, KA
Published in Journal of medicinal chemistry (06.10.2005)

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Determination of the tautomeric equilibrium of Psi-uridine in the basic solution

Determination of the tautomeric equilibrium of Psi-uridine in the basic solution

by Luyten, I, Pankiewicz, KW, Watanabe, KA, Chattopadhyaya, J
Published in Journal of organic chemistry (20.02.1998)

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Synthesis of N super(3),5'-Cyclo-4-( beta -D-ribofuranosyl) -vic-triazolo[4,5-b]pyridin-5-one, a Novel Compound with Anti-Hepatitis C Virus Activity

Synthesis of N super(3),5'-Cyclo-4-( beta -D-ribofuranosyl) -vic-triazolo[4,5-b]pyridin-5-one, a Novel Compound with Anti-Hepatitis C Virus Activity

by Wang, P, Hollecker, L, Pankiewicz, K W, Patterson, SE, Whitaker, T, McBrayer, T R, Tharnish, P M, Sidwell, R W, Stuyver, L J, Otto, MJ, Schinazi, R F, Watanabe, KA
Published in Journal of medicinal chemistry (18.11.2004)

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Efficient synthesis of methylenebis(phosphonate) analogues of P-1,P-2-disubstituted pyrophosphates of biological interest. A novel plausible mechanism

Efficient synthesis of methylenebis(phosphonate) analogues of P-1,P-2-disubstituted pyrophosphates of biological interest. A novel plausible mechanism

by Pankiewicz, KW, Lesiak, K, Watanabe, KA
Published in Journal of the American Chemical Society (23.04.1997)

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Synthesis of 2′-fluoro-5-[ 11C]-methyl-1-β- d-arabinofuranosyluracil ([ 11C]-FMAU): A potential nucleoside analog for in vivo study of cellular proliferation with PET

Synthesis of 2′-fluoro-5-[ 11C]-methyl-1-β- d-arabinofuranosyluracil ([ 11C]-FMAU): A potential nucleoside analog for in vivo study of cellular proliferation with PET

by Conti, Peter S., Alauddin, Mian M., Fissekis, John R., Schmall, Bernard, Watanabe, Kyochi A.
Published in Nuclear medicine and biology (01.08.1995)

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