A phase 1 ascending dose study of a subcutaneously administered factor IXa inhibitor and its active control agent
VAVALLE, J. P., RUSCONI, C. P., ZELENKOFSKE, S., WARGIN, W. A., ALEXANDER, J. H., BECKER, R. C.
Published in Journal of thrombosis and haemostasis (01.07.2012)
Published in Journal of thrombosis and haemostasis (01.07.2012)
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The effect of the REG2 Anticoagulation System on thrombin generation kinetics: a pharmacodynamic and pharmacokinetic first-in-human study
Vavalle, J. P., Rusconi, C. P., Zelenkofske, S., Wargin, W. A., Ortel, T. L., Alexander, J. H., Povsic, T. J., Becker, R. C.
Published in Journal of thrombosis and thrombolysis (01.10.2014)
Published in Journal of thrombosis and thrombolysis (01.10.2014)
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Dose Selection for a Direct and Selective Factor IXa Inhibitor and its Complementary Reversal Agent: Translating Pharmacokinetic and Pharmacodynamic Properties of the REG1 System to Clinical Trial Design
Povsic, T. J., Cohen, M. G., Chan, M. Y., Zelenkofske, S. L., Wargin, W. A., Harrington, R. A., Alexander, J. H., Rusconi, C. P., Becker, R. C.
Published in Journal of thrombosis and thrombolysis (01.07.2011)
Published in Journal of thrombosis and thrombolysis (01.07.2011)
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Journal Article
Importance of the Organ-Independent Elimination of Cisatracurium
Kisor, David F., Schmith, Virginia D., Wargin, William A., Lien, Cynthia A., Ornstein, Eugene, Cook, D. Ryan
Published in Anesthesia and analgesia (01.11.1996)
Published in Anesthesia and analgesia (01.11.1996)
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Journal Article
Bidirectional interaction of valproate and lamotrigine in healthy subjects
Anderson, G D, Yau, M K, Gidal, B E, Harris, S J, Levy, R H, Lai, A A, Wolf, K B, Wargin, W A, Dren, A T
Published in Clinical pharmacology and therapeutics (01.08.1996)
Published in Clinical pharmacology and therapeutics (01.08.1996)
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Pharmacokinetics of RheothRx Injection in Healthy Male Volunteers
Jewell, R.C., Khor, S.P., Kisor, D.F., LaCroix, K.A.K., Wargin, W.A.
Published in Journal of pharmaceutical sciences (01.07.1997)
Published in Journal of pharmaceutical sciences (01.07.1997)
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The pharmacokinetics and pharmacodynamics of the stereoisomers of mivacurium in patients receiving nitrous oxide/opioid/barbiturate anesthesia
Lien, C A, Schmith, V D, Embree, P B, Belmont, M R, Wargin, W A, Savarese, J J
Published in Anesthesiology (Philadelphia) (01.06.1994)
Published in Anesthesiology (Philadelphia) (01.06.1994)
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Journal Article
Pharmacokinetics and safety of lamotrigine (Lamictal®) in patients with epilepsy
Ramsay, R.Eugene, Pellock, John M., Garnett, William R., Sanchez, Ramon M., Valakas, Antonia M., Wargin, William A., Lai, Alien A., Hubbell, James, Chern, W.H., Allsup, Thurman, Otto, Vicky
Published in Epilepsy research (01.11.1991)
Published in Epilepsy research (01.11.1991)
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Journal Article
Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors
Rowinsky, E K, Noe, D A, Trump, D L, Winer, E P, Lucas, V S, Wargin, W A, Hohneker, J A, Lubejko, B, Sartorius, S E, Ettinger, D S
Published in Journal of clinical oncology (01.09.1994)
Published in Journal of clinical oncology (01.09.1994)
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Pharmacokinetics of methylphenidate in man, rat and monkey
WARGIN, W, PATRICK, K, KILTS, C, GUALTIERI, C. T, ELLINGTON, K, MUELLER, R. A, KRAEMER, G, BREESE, G. R
Published in The Journal of pharmacology and experimental therapeutics (01.08.1983)
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Published in The Journal of pharmacology and experimental therapeutics (01.08.1983)
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Pharmacokinetics and Pharmacodynamics of Doxacurium in Young and Elderly Patients During Isoflurane Anesthesia
Dresner, David L., Basta, Salvatore J., Ali, Hassan H., Schwartz, Ann F., Embree, Patricia B., Wargin, William A., Lai, Allen A., Brady, Karen A., Savarese, John J.
Published in Anesthesia and analgesia (01.11.1990)
Published in Anesthesia and analgesia (01.11.1990)
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THE PHARMACOKINETICS OF 1954U89, 1, 3-DIAMINO-7-(1-ETHYLPROPYL)-8-METHYL-7H-PYRROLO-(3, 2-f )QUINAZOLINE, IN DOGS AND RATS AFTER INTRAVENOUS AND ORAL ADMINISTRATION
STUDENBERG, S. D., WOOLLEY, J. L., DEANGELIS, D. V., WARGIN, W. A.
Published in Biopharmaceutics & drug disposition (01.07.1997)
Published in Biopharmaceutics & drug disposition (01.07.1997)
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Pegnivacogin results in near complete FIX inhibition in acute coronary syndrome patients: RADAR pharmacokinetic and pharmacodynamic substudy
Povsic, Thomas J., Wargin, William A., Alexander, John H., Krasnow, Joshua, Krolick, Merill, Cohen, Mauricio G., Mehran, Roxana, Buller, Christopher E., Bode, Christoph, Zelenkofske, Steven L., Rusconi, Christopher P., Becker, Richard C.
Published in European heart journal (01.10.2011)
Published in European heart journal (01.10.2011)
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Journal Article
Pharmacokinetics of oral and transdermal triprolidine
Miles, M V, Balasubramanian, R, Pittman, A W, Grossman, S H, Pappa, K A, Smith, M F, Wargin, W A, Findlay, J W, Poust, R I, Frosolono, M F
Published in Journal of clinical pharmacology (01.06.1990)
Published in Journal of clinical pharmacology (01.06.1990)
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Antipyrine kinetics following partial blood exchange with Fluosol-DA in the rat
Shrewsbury, R P, White, S G, Pollack, G M, Wargin, W A
Published in Journal of pharmacy and pharmacology (01.12.1986)
Published in Journal of pharmacy and pharmacology (01.12.1986)
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Crisnatol mesylate: phase I dose escalation by extending infusion duration
Poplin, E A, Chabot, G G, Tuttle, R L, Lucas, S, Wargin, W A, Baker, L H
Published in Investigational new drugs (01.02.1991)
Published in Investigational new drugs (01.02.1991)
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