Therapeutic opportunities within the DNA damage response
Pearl, Laurence H, Schierz, Amanda C, Ward, Simon E, Al-Lazikani, Bissan, Pearl, Frances M G
Published in Nature reviews. Cancer (01.03.2015)
Published in Nature reviews. Cancer (01.03.2015)
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Epidermal Barrier Dysfunction in Atopic Dermatitis
Cork, Michael J., Danby, Simon G., Vasilopoulos, Yiannis, Hadgraft, Jonathan, Lane, Majella E., Moustafa, Manar, Guy, Richard H., MacGowan, Alice L., Tazi-Ahnini, Rachid, Ward, Simon J.
Published in Journal of investigative dermatology (01.08.2009)
Published in Journal of investigative dermatology (01.08.2009)
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New perspectives on epidermal barrier dysfunction in atopic dermatitis: Gene–environment interactions
Cork, Michael J., Robinson, Darren A., Vasilopoulos, Yiannis, Ferguson, Adam, Moustafa, Manar, MacGowan, Alice, Duff, Gordon W., Ward, Simon J., Tazi-Ahnini, Rachid
Published in Journal of allergy and clinical immunology (01.07.2006)
Published in Journal of allergy and clinical immunology (01.07.2006)
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CCRK is a novel signalling hub exploitable in cancer immunotherapy
Mok, Myth T., Zhou, Jingying, Tang, Wenshu, Zeng, Xuezhen, Oliver, Antony W., Ward, Simon E., Cheng, Alfred S.
Published in Pharmacology & therapeutics (Oxford) (01.06.2018)
Published in Pharmacology & therapeutics (Oxford) (01.06.2018)
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Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan
Meisenberg, Cornelia, Gilbert, Duncan C, Chalmers, Anthony, Haley, Vikki, Gollins, Simon, Ward, Simon E, El-Khamisy, Sherif F
Published in Molecular cancer therapeutics (01.02.2015)
Published in Molecular cancer therapeutics (01.02.2015)
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Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2
Hornyak, Peter, Askwith, Trevor, Walker, Sarah, Komulainen, Emilia, Paradowski, Michael, Pennicott, Lewis E, Bartlett, Edward J, Brissett, Nigel C, Raoof, Ali, Watson, Mandy, Jordan, Allan M, Ogilvie, Donald J, Ward, Simon E, Atack, John R, Pearl, Laurence H, Caldecott, Keith W, Oliver, Antony W
Published in Biochemical journal (01.07.2016)
Published in Biochemical journal (01.07.2016)
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Lung function indices for predicting mortality in COPD
BOUTOU, Afroditi K, SHRIKRISHNA, Dinesh, TANNER, Rebecca J, SMITH, Cayley, KELLY, Julia L, WARD, Simon P, POLKEY, Michael I, HOPKINSON, Nicholas S
Published in The European respiratory journal (01.09.2013)
Published in The European respiratory journal (01.09.2013)
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Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors
Henderson, Scott H, Sorrell, Fiona, Bennett, James, Fedorov, Oleg, Hanley, Marcus T, Godoi, Paulo H, Ruela de Sousa, Roberta, Robinson, Sean, Ashall-Kelly, Alexander, Hopkins Navratilova, Iva, Walter, Daryl S, Elkins, Jonathan M, Ward, Simon E
Published in Journal of medicinal chemistry (12.08.2021)
Published in Journal of medicinal chemistry (12.08.2021)
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Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion
Cockerill, G. Stuart, Angell, Richard M, Bedernjak, Alexandre, Chuckowree, Irina, Fraser, Ian, Gascon-Simorte, Jose, Gilman, Morgan S. A, Good, James A. D, Harland, Rachel, Johnson, Sara M, Ludes-Meyers, John H, Littler, Edward, Lumley, James, Lunn, Graham, Mathews, Neil, McLellan, Jason S, Paradowski, Michael, Peeples, Mark E, Scott, Claire, Tait, Dereck, Taylor, Geraldine, Thom, Michelle, Thomas, Elaine, Villalonga Barber, Carol, Ward, Simon E, Watterson, Daniel, Williams, Gareth, Young, Paul, Powell, Kenneth
Published in Journal of medicinal chemistry (08.04.2021)
Published in Journal of medicinal chemistry (08.04.2021)
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Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer
Scott, Fiona, Fala, Angela M., Pennicott, Lewis E., Reuillon, Tristan D., Massirer, Katlin B., Elkins, Jonathan M., Ward, Simon E.
Published in Bioorganic & medicinal chemistry letters (15.04.2020)
Published in Bioorganic & medicinal chemistry letters (15.04.2020)
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Comparative Analysis of Small-Molecule LIMK1/2 Inhibitors: Chemical Synthesis, Biochemistry, and Cellular Activity
Collins, Ross, Lee, Hyunah, Jones, D. Heulyn, Elkins, Jonathan M., Gillespie, Jason A., Thomas, Carys, Baldwin, Alex G., Jones, Kimberley, Waters, Loren, Paine, Marie, Atack, John R., Ward, Simon E., Grubisha, Olivera, Foley, David W.
Published in Journal of medicinal chemistry (27.10.2022)
Published in Journal of medicinal chemistry (27.10.2022)
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Challenges for and current status of research into positive modulators of AMPA receptors
Ward, Simon E, Bax, Benjamin D, Harries, Mark
Published in British journal of pharmacology (01.05.2010)
Published in British journal of pharmacology (01.05.2010)
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Imidazo[1,2-b]pyridazines as inhibitors of DYRK kinases
Henderson, Scott H., Sorrell, Fiona J., Bennett, James M., Fedorov, Oleg, Hanley, Marcus T., Godoi, Paulo H., Ruela de Sousa, Roberta, Robinson, Sean, Navratilova, Iva Hopkins, Elkins, Jonathan M., Ward, Simon E.
Published in European journal of medicinal chemistry (05.04.2024)
Published in European journal of medicinal chemistry (05.04.2024)
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Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan
Meisenberg, Cornelia, Ashour, Mohamed E, El-Shafie, Lamia, Liao, Chunyan, Hodgson, Adam, Pilborough, Alice, Khurram, Syed A, Downs, Jessica A, Ward, Simon E, El-Khamisy, Sherif F
Published in Nucleic acids research (17.02.2017)
Published in Nucleic acids research (17.02.2017)
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