Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization
Graves, Bradford, Thompson, Thelma, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Di Lello, Paola, Fry, David, Garvie, Colin, Huang, Kuo-Sen, Gao, Lin, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2012)
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Journal Article
Rational Design of Highly Selective Spleen Tyrosine Kinase Inhibitors
Lucas, Matthew C., Goldstein, David M., Hermann, Johannes C., Kuglstatter, Andreas, Liu, Wenjian, Luk, Kin Chun, Padilla, Fernando, Slade, Michelle, Villaseñor, Armando G., Wanner, Jutta, Xie, Wenwei, Zhang, Xiaohu, Liao, Cheng
Published in Journal of medicinal chemistry (13.12.2012)
Published in Journal of medicinal chemistry (13.12.2012)
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Journal Article
Reversible linkage of two distinct small molecule inhibitors of Myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines
Wanner, Jutta, Romashko, Darlene, Werner, Douglas S, May, Earl W, Peng, Yue, Schulz, Ryan, Foreman, Kenneth W, Russo, Suzanne, Arnold, Lee D, Pingle, Maneesh, Bergstrom, Donald E, Barany, Francis, Thomson, Stuart
Published in PloS one (15.04.2015)
Published in PloS one (15.04.2015)
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Journal Article
The mechanism of action of ramoplanin and enduracidin
Fang, Xiao, Tiyanont, Kittichoat, Zhang, Yi, Wanner, Jutta, Boger, Dale, Walker, Suzanne
Published in Molecular bioSystems (01.01.2006)
Published in Molecular bioSystems (01.01.2006)
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Journal Article
Total Synthesis of the Ramoplanin A2 and Ramoplanose Aglycon
Jiang, Wanlong, Wanner, Jutta, Lee, Richard J, Bounaud, Pierre-Yves, Boger, Dale L
Published in Journal of the American Chemical Society (19.02.2003)
Published in Journal of the American Chemical Society (19.02.2003)
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Journal Article
Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc
Lemoine, Rémy C., Petersen, Ann C., Setti, Lina, Baldinger, Thomas, Wanner, Jutta, Jekle, Andreas, Heilek, Gabrielle, deRosier, André, Ji, Changhua, Rotstein, David M.
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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Journal Article
Recent advances in malaria drug discovery
Biamonte, Marco A., Wanner, Jutta, Le Roch, Karine G.
Published in Bioorganic & medicinal chemistry letters (15.05.2013)
Published in Bioorganic & medicinal chemistry letters (15.05.2013)
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Journal Article
Abstract 5153: Tunable Drug Conjugates: a differentiated drug conjugate (DC) platform
Hickey, Sara C., Nanna, Alex R., Nguyen, Hanh N., Ofori, Leslie, Rader, Christoph, Rood, Michael K., Wanner, Jutta, Werner, Doug S.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Druggability assessment of protein-protein interfaces
Wanner, Jutta, Fry, David C, Peng, Zhengwei, Roberts, John
Published in Future medicinal chemistry (01.12.2011)
Published in Future medicinal chemistry (01.12.2011)
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Journal Article
Pyrrolopyrazines as Selective Spleen Tyrosine Kinase Inhibitors
Padilla, Fernando, Bhagirath, Niala, Chen, Shaoqing, Chiao, Eric, Goldstein, David M, Hermann, Johannes C, Hsu, Jonathan, Kennedy-Smith, Joshua J, Kuglstatter, Andreas, Liao, Cheng, Liu, Wenjian, Lowrie, Lee E, Luk, Kin Chun, Lynch, Stephen M, Menke, John, Niu, Linghao, Owens, Timothy D, O-Yang, Counde, Railkar, Aruna, Schoenfeld, Ryan C, Slade, Michelle, Steiner, Sandra, Tan, Yun-Chou, Villaseñor, Armando G, Wang, Ce, Wanner, Jutta, Xie, Wenwei, Xu, Daigen, Zhang, Xiaohu, Zhou, Mingyan, Lucas, Matthew C
Published in Journal of medicinal chemistry (28.02.2013)
Published in Journal of medicinal chemistry (28.02.2013)
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Journal Article
Abstract B43: Reversible linkage of two distinct small molecule inhibitors of MYC generates a more potent and selective dimeric inhibitor that is active in cancer cell lines over-expressing MYC
Wanner, Jutta, Romashko, Darlene, Werner, Douglas S., May, Earl W., Peng, Yue, Schulz, Ryan, Foreman, Kenneth W., Russo, Suzanne, Arnold, Lee D., Pingle, Maneesh, Bergstrom, Donald E., Barany, Francis, Thomson, Stuart
Published in Molecular cancer research (01.10.2015)
Published in Molecular cancer research (01.10.2015)
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Journal Article
Evaluation of secondary amide replacements in a series of CCR5 antagonists as a means to increase intrinsic membrane permeability. Part 1: Optimization of gem-disubstituted azacycles
Lemoine, Rémy C., Petersen, Ann C., Setti, Lina, Wanner, Jutta, Jekle, Andreas, Heilek, Gabrielle, deRosier, André, Ji, Changhua, Berry, Pamela, Rotstein, David
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
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Journal Article
Activation of the p53 pathway by small-moleculeinduced MDM2 and MDMX dimerization
Graves, Bradford, Thompson, Thelma, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Di Lello, Paola, Fry, David, Garvie, Colin, Huang, Kuo-Sen, Gao, Lin, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T.
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2012)
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Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2012)
Journal Article
Abstract C128: Small-molecule antagonists of MDM2 and MDMX
Thompson, Thelma, Graves, Bradford, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Huang, Kuo-Sen, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T.
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Journal Article
IRAK4 [15A] [32B] PYRAZOLO[15A]PYRIMIDINE AND THIENO[32B]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS
ZHAI YANSHENG, TALAMAS FRANCISCO XAVIER, ARORA NIDHI, KUGLSTATTER ANDREAS, CHEN SHAOQING, LABADIE SHARADA SHENVI, LIN CLARA JEOU JEN, PAPP EVA, WANNER JUTTA, LUCAS MATTHEW C, MOORE AMY GERALDINE, HERMANN JOHANNES CORNELIUS
Year of Publication 03.07.2019
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Year of Publication 03.07.2019
Patent
Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists
Lemoine, Rémy C., Petersen, Ann C., Setti, Lina, Chen, Lijing, Wanner, Jutta, Jekle, Andreas, Heilek, Gabrielle, deRosier, André, Ji, Changhua, Rotstein, David M.
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
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Journal Article
IMIDAZOPYRIDAZINE COMPOUNDS
PADILLA FERNANDO, KUGLSTATTER ANDREAS, WANNER JUTTA, LUCAS MATTHEW C, HERMANN JOHANNES CORNELIUS, ZHANG XIAOHU
Year of Publication 01.08.2014
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Year of Publication 01.08.2014
Patent