Gene expression profiling identifies the role of Zac1 in cervical cancer metastasis
Su, Hui-Chen, Wu, Sheng-Cheng, Yen, Li-Chen, Chiao, Li-Kang, Wang, Jehng-Kang, Chiu, Yi-Lin, Ho, Ching-Liang, Huang, Shih-Ming
Published in Scientific reports (16.07.2020)
Published in Scientific reports (16.07.2020)
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The spatiotemporal control of human matriptase action on its physiological substrates: a case against a direct role for matriptase proteolytic activity in profilaggrin processing and desquamation
Lin, Chen-Yong, Wang, Jehng-Kang, Johnson, Michael D.
Published in Human cell : official journal of Human Cell Research Society (01.07.2020)
Published in Human cell : official journal of Human Cell Research Society (01.07.2020)
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Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity
Tseng, Chun-Che, Jia, Bailing, Barndt, Robert, Gu, Yayun, Chen, Chien-Yu, Tseng, I-Chu, Su, Sheng-Fang, Wang, Jehng-Kang, Johnson, Michael D, Lin, Chen-Yong
Published in PloS one (22.08.2017)
Published in PloS one (22.08.2017)
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Treatment efficacy of low-dose 5-fluorouracil with ultrasound in mediating 5-fluorouracil-loaded microbubble cavitation in head and neck cancer
Liao, Ai-Ho, Lee, Yu-An, Lin, Dao-Lung, Chuang, Ho-Chiao, Wang, Jehng-Kang, Chang, Ching-En, Li, Hsiang-Tzu, Wu, Ting-Yi, Shih, Cheng-Ping, Wang, Chih-Hung, Chu, Yueng-Hsiang
Published in Drug delivery (01.12.2023)
Published in Drug delivery (01.12.2023)
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Targeted deletion of HAI-1 increases prostasin proteolysis but decreases matriptase proteolysis in human keratinocytes
Lu, Dajun D., Gu, Yayun, Li, Sheng-Wen A., Barndt, Robert J., Huang, Shih-Ming, Wang, Jehng-Kang, Su, Hui Chen, Johnson, Michael D., Lin, Chen-Yong
Published in Human cell : official journal of Human Cell Research Society (01.05.2021)
Published in Human cell : official journal of Human Cell Research Society (01.05.2021)
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Mild acidity likely accelerates the physiological matriptase autoactivation process: a comparative study between spontaneous and acid-induced matriptase zymogen activation
Jia, Bailing, Thompson, Hamishi A., Barndt, Robert B., Chiu, Yi-Lin, Lee, Mon-Juan, Lee, See-Chi, Wang, Jehng-Kang, Tang, Hung-Jen, Lin, Chen-Yong, Johnson, Michael D.
Published in Human cell : official journal of Human Cell Research Society (01.10.2020)
Published in Human cell : official journal of Human Cell Research Society (01.10.2020)
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Correction: Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin
Lee, Shiao-Pieng, Kao, Chen-Yu, Chang, Shun-Cheng, Chiu, Yi-Lin, Chen, Yen-Ju, Chen, Ming-Hsing G, Chang, Chun-Chia, Lin, Yu-Wen, Chiang, Chien-Ping, Wang, Jehng-Kang, Lin, Chen-Yong, Johnson, Michael D
Published in PloS one (31.05.2018)
Published in PloS one (31.05.2018)
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The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane
Tseng, Chun-Che, Jia, Bailing, Barndt, Robert B, Dai, Yang-Hong, Chen, Yu Hsin, Du, Po-Wen A, Wang, Jehng-Kang, Tang, Hung-Jen, Lin, Chen-Yong, Johnson, Michael D
Published in PloS one (12.02.2020)
Published in PloS one (12.02.2020)
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Journal Article
Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin
Lee, Shiao-Pieng, Kao, Chen-Yu, Chang, Shun-Cheng, Chiu, Yi-Lin, Chen, Yen-Ju, Chen, Ming-Hsing G, Chang, Chun-Chia, Lin, Yu-Wen, Chiang, Chien-Ping, Wang, Jehng-Kang, Lin, Chen-Yong, Johnson, Michael D
Published in PloS one (13.02.2018)
Published in PloS one (13.02.2018)
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Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation
Lai, Chih-Hsin, Lai, Ying-Jung J, Chou, Feng-Pai, Chang, Hsiang-Hua D, Tseng, Chun-Che, Johnson, Michael D, Wang, Jehng-Kang, Lin, Chen-Yong
Published in PloS one (04.04.2016)
Published in PloS one (04.04.2016)
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HAI-1 is required for the novel role of FGFBP1 in maintenance of cell morphology and F-actin rearrangement in human keratinocytes
Lu, Dajun D., Huang, Nanxi, Li, Sheng-Wen A., Fang, Jessica R., Lai, Chih-Hsin, Wang, Jehng-Kang, Chan, Khee-Siang, Johnson, Michael D., Lin, Chen-Yong
Published in Human cell : official journal of Human Cell Research Society (01.07.2023)
Published in Human cell : official journal of Human Cell Research Society (01.07.2023)
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Journal Article
Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2
Shiao, Frank, Liu, Li-Ching O, Huang, Nanxi, Lai, Ying-Jung J, Barndt, Robert J, Tseng, Chun-Che, Wang, Jehng-Kang, Jia, Bailing, Johnson, Michael D, Lin, Chen-Yong
Published in PloS one (26.01.2017)
Published in PloS one (26.01.2017)
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The difference in the intracellular Arg/Lys-rich and EHLVY motifs contributes to distinct subcellular distribution of HAI-1 versus HAI-2
Huang, Nanxi, Barndt, Robert B., Lu, Dajun D., Wang, Qiaochu, Huang, Shih-Ming, Wang, Jehng-Kang, Chang, Ping-Ying, Chen, Chao-Yang, Hu, Je-Ming, Su, Hui-Chen, Johnson, Michael D., Lin, Chen-Yong
Published in Human cell : official journal of Human Cell Research Society (2022)
Published in Human cell : official journal of Human Cell Research Society (2022)
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Journal Article
Regulation of the Matriptase-Prostasin Cell Surface Proteolytic Cascade by Hepatocyte Growth Factor Activator Inhibitor-1 during Epidermal Differentiation
Chen, Ya-Wen, Wang, Jehng-Kang, Chou, Feng-Pai, Chen, Chiu-Yuan, Rorke, Ellen A., Chen, Li-Mei, Chai, Karl X., Eckert, Richard L., Johnson, Michael D., Lin, Chen-Yong
Published in The Journal of biological chemistry (08.10.2010)
Published in The Journal of biological chemistry (08.10.2010)
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Matriptase and prostasin proteolytic activities are differentially regulated in normal and wounded skin
Chang, Shun-Cheng, Chiang, Chien-Ping, Lai, Chih-Hsin, Du, Po-Wen A., Hung, Yu-Sin, Chen, Yu-Hsuan, Yang, Hui-Yu, Fang, Hao-Yu, Lee, Shiao-Pieng, Tang, Hung-Jen, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Published in Human cell : official journal of Human Cell Research Society (01.10.2020)
Published in Human cell : official journal of Human Cell Research Society (01.10.2020)
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Journal Article
N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin
Lai, Ying-Jung J, Chang, Hsiang-Hua D, Lai, Hongyu, Xu, Yuan, Shiao, Frank, Huang, Nanxi, Li, Linpei, Lee, Ming-Shyue, Johnson, Michael D, Wang, Jehng-Kang, Lin, Chen-Yong
Published in PloS one (14.07.2015)
Published in PloS one (14.07.2015)
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Journal Article
Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity
Chiu, Yi-Lin, Wu, Yi-Ying, Barndt, Robert B., Lin, Yu-Wen, Sytwo, Hou-Ping, Cheng, Amy, Yang, Kacy, Chan, Khee-Siang, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Published in Genes & diseases (01.07.2022)
Published in Genes & diseases (01.07.2022)
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Journal Article
Imbalanced Matriptase Pericellular Proteolysis Contributes to the Pathogenesis of Malignant B-Cell Lymphomas
Chou, Feng-Pai, Chen, Ya-Wen, Zhao, Xianfeng F, Xu-Monette, Zijun Y, Young, Ken H, Gartenhaus, Ronald B, Wang, Jehng-Kang, Kataoka, Hiroaki, Zuo, Annie H, Barndt, Robert J, Johnson, Michael, Lin, Chen-Yong
Published in The American journal of pathology (01.10.2013)
Published in The American journal of pathology (01.10.2013)
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Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells
Chang, Hsiang-Hua D, Xu, Yuan, Lai, Hongyu, Yang, Xiaoyu, Tseng, Chun-Che, Lai, Ying-Jung J, Pan, Yu, Zhou, Emily, Johnson, Michael D, Wang, Jehng-Kang, Lin, Chen-Yong
Published in PloS one (18.03.2015)
Published in PloS one (18.03.2015)
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