Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer
Nagathihalli, Nagaraj S, Castellanos, Jason A, Shi, Chanjuan, Beesetty, Yugandhar, Reyzer, Michelle L, Caprioli, Richard, Chen, Xi, Walsh, Alex J, Skala, Melissa C, Moses, Harold L, Merchant, Nipun B
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2015)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2015)
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Journal Article
Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response
Walsh, Alex J, Castellanos, Jason A, Nagathihalli, Nagaraj S, Merchant, Nipun B, Skala, Melissa C
Published in Pancreas (01.07.2016)
Published in Pancreas (01.07.2016)
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Journal Article
In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment
Shah, Amy T, Diggins, Kirsten E, Walsh, Alex J, Irish, Jonathan M, Skala, Melissa C
Published in Neoplasia (New York, N.Y.) (01.12.2015)
Published in Neoplasia (New York, N.Y.) (01.12.2015)
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Journal Article
Drug response in organoids generated from frozen primary tumor tissues
Walsh, Alex J., Cook, Rebecca S., Sanders, Melinda E., Arteaga, Carlos L., Skala, Melissa C.
Published in Scientific reports (07.01.2016)
Published in Scientific reports (07.01.2016)
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Journal Article
Optical metabolic imaging of treatment response in human head and neck squamous cell carcinoma
Shah, Amy T, Demory Beckler, Michelle, Walsh, Alex J, Jones, William P, Pohlmann, Paula R, Skala, Melissa C
Published in PloS one (04.03.2014)
Published in PloS one (04.03.2014)
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Journal Article
Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth
Benavides, Oscar R, Gibbs, Holly C, White, Berkley P, Kaunas, Roland, Gregory, Carl A, Walsh, Alex J, Maitland, Kristen C
Published in PloS one (28.03.2023)
Published in PloS one (28.03.2023)
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Journal Article
Carbomer-based adjuvant elicits CD8 T-cell immunity by inducing a distinct metabolic state in cross-presenting dendritic cells
Lee, Woojong, Kingstad-Bakke, Brock, Paulson, Brett, Larsen, Autumn, Overmyer, Katherine, Marinaik, Chandranaik B, Dulli, Kelly, Toy, Randall, Vogel, Gabriela, Mueller, Katherine P, Tweed, Kelsey, Walsh, Alex J, Russell, Jason, Saha, Krishanu, Reyes, Leticia, Skala, Melissa C, Sauer, John-Demian, Shayakhmetov, Dmitry M, Coon, Joshua, Roy, Krishnendu, Suresh, M
Published in PLoS pathogens (14.01.2021)
Published in PLoS pathogens (14.01.2021)
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Journal Article
In vivo fluorescence lifetime imaging of macrophage intracellular metabolism during wound responses in zebrafish
Miskolci, Veronika, Tweed, Kelsey E, Lasarev, Michael R, Britt, Emily C, Walsh, Alex J, Zimmerman, Landon J, McDougal, Courtney E, Cronan, Mark R, Fan, Jing, Sauer, John-Demian, Skala, Melissa C, Huttenlocher, Anna
Published in eLife (24.02.2022)
Published in eLife (24.02.2022)
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Journal Article
Comparison of phasor analysis and biexponential decay curve fitting of autofluorescence lifetime imaging data for machine learning prediction of cellular phenotypes
Hu, Linghao, Ter Hofstede, Blanche, Sharma, Dhavan, Zhao, Feng, Walsh, Alex J
Published in Frontiers in bioinformatics (29.06.2023)
Published in Frontiers in bioinformatics (29.06.2023)
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Journal Article
Perfusability and immunogenicity of implantable pre-vascularized tissues recapitulating features of native capillary network
Sharma, Dhavan, Sharma, Archita, Hu, Linghao, Chen, Te-An, Voon, Sarah, Bayless, Kayla J., Goldman, Jeremy, Walsh, Alex J., Zhao, Feng
Published in Bioactive materials (01.12.2023)
Published in Bioactive materials (01.12.2023)
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Journal Article
Label-free spatially maintained measurements of metabolic phenotypes in cells
Hu, Linghao, Wang, Nianchao, Bryant, Joshua D, Liu, Lin, Xie, Linglin, West, A Phillip, Walsh, Alex J
Published in Frontiers in bioengineering and biotechnology (28.11.2023)
Published in Frontiers in bioengineering and biotechnology (28.11.2023)
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Journal Article
Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells
Zhang, Qin, Jeppesen, Dennis K, Higginbotham, James N, Demory Beckler, Michelle, Poulin, Emily J, Walsh, Alex J, Skala, Melissa C, McKinley, Eliot T, Manning, H. Charles, Hight, Matthew R, Schulte, Michael L, Watt, Kimberly R, Ayers, G. Daniel, Wolf, Melissa M, Andrejeva, Gabriela, Rathmell, Jeffrey C, Franklin, Jeffrey L, Coffey, Robert J
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
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Journal Article
Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer
Walsh, Alex J, Cook, Rebecca S, Sanders, Melinda E, Aurisicchio, Luigi, Ciliberto, Gennaro, Arteaga, Carlos L, Skala, Melissa C
Published in Cancer research (Chicago, Ill.) (15.09.2014)
Published in Cancer research (Chicago, Ill.) (15.09.2014)
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Journal Article
Optical Metabolic Imaging Identifies Glycolytic Levels, Subtypes, and Early-Treatment Response in Breast Cancer
WALSH, Alex J, COOK, Rebecca S, MANNING, H. Charles, HICKS, Donna J, LAFONTANT, Alec, ARTEAGA, Carlos L, SKALA, Melissa C
Published in Cancer research (Chicago, Ill.) (15.10.2013)
Published in Cancer research (Chicago, Ill.) (15.10.2013)
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Journal Article
Fluorescence intensity and lifetime redox ratios detect metabolic perturbations in T cells
Hu, Linghao, Wang, Nianchao, Cardona, Elizabeth, Walsh, Alex J.
Published in Biomedical optics express (01.10.2020)
Published in Biomedical optics express (01.10.2020)
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Journal Article
Functional Optical Imaging of Primary Human Tumor Organoids: Development of a Personalized Drug Screen
Walsh, Alex J, Cook, Rebecca S, Skala, Melissa C
Published in Journal of Nuclear Medicine (01.09.2017)
Published in Journal of Nuclear Medicine (01.09.2017)
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Journal Article