Scalable Synthesis and Isolation of the Four Stereoisomers of Methyl 1-Amino-3-(4-bromophenyl)cyclopentanecarboxylate, Useful Intermediates for the Synthesis of S1P1 Receptor Agonists
Wallace, Grier A, Gordon, Thomas D, Hayes, Martin E, Konopacki, Donald B, Fix-Stenzel, Shannon R, Zhang, Xiaolei, Grongsaard, Pintipa, Cusack, Kevin P, Schaffter, Lisa M, Henry, Rodger F, Stoffel, Robert H
Published in Journal of organic chemistry (03.07.2009)
Published in Journal of organic chemistry (03.07.2009)
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Hit-to-lead evaluation of a novel class of sphingosine 1-phosphate lyase inhibitors
Dinges, Jurgen, Harris, Christopher M., Wallace, Grier A., Argiriadi, Maria A., Queeney, Kara L., Perron, Denise C., Dominguez, Eric, Kebede, Tegest, Desino, Kelly E., Patel, Hetal, Vasudevan, Anil
Published in Bioorganic & medicinal chemistry letters (01.05.2016)
Published in Bioorganic & medicinal chemistry letters (01.05.2016)
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Multigram Synthesis of the C29−C51 Subunit and Completion of the Total Synthesis of Altohyrtin C (Spongistatin 2)
Heathcock, Clayton H, McLaughlin, Mark, Medina, Jesus, Hubbs, Jed L, Wallace, Grier A, Scott, Robert, Claffey, Michele M, Hayes, Christopher J, Ott, Gregory R
Published in Journal of the American Chemical Society (22.10.2003)
Published in Journal of the American Chemical Society (22.10.2003)
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Discovery of small molecule benzimidazole antagonists of the chemokine receptor CXCR3
Hayes, Martin E., Wallace, Grier A., Grongsaard, Pintipa, Bischoff, Agnieszka, George, Dawn M., Miao, Wenyan, McPherson, Michael J., Stoffel, Robert H., Green, David W., Roth, Gregory P.
Published in Bioorganic & medicinal chemistry (01.03.2008)
Published in Bioorganic & medicinal chemistry (01.03.2008)
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A stereoselective and scalable synthesis of a conformationally constrained S1P1 agonist
Fix-Stenzel, Shannon R., Hayes, Martin E., Zhang, Xiaolei, Wallace, Grier A., Grongsaard, Pintipa, Schaffter, Lisa M., Hannick, Steven M., Franczyk, Thaddeus S., Stoffel, Robert H., Cusack, Kevin P.
Published in Tetrahedron letters (01.07.2009)
Published in Tetrahedron letters (01.07.2009)
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Lead identification of 2-iminobenzimidazole antagonists of the chemokine receptor CXCR3
Hayes, Martin E., Breinlinger, Eric C., Wallace, Grier A., Grongsaard, Pintipa, Miao, Wenyan, McPherson, Michael J., Stoffel, Robert H., Green, David W., Roth, Gregory P.
Published in Bioorganic & medicinal chemistry (01.04.2008)
Published in Bioorganic & medicinal chemistry (01.04.2008)
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Stereoselective Total Syntheses and Reassignment of Stereochemistry of the Freshwater Cyanobacterial Hepatotoxins Cylindrospermopsin and 7-Epicylindrospermopsin
Heintzelman, Geoffrey R, Fang, Wen-Kui, Keen, Stephen P, Wallace, Grier A, Weinreb, Steven M
Published in Journal of the American Chemical Society (17.04.2002)
Published in Journal of the American Chemical Society (17.04.2002)
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Synthesis of the C29−C44 Portion of Spongistatin 1 (Altohyrtin A)
Wallace, Grier A, Scott, Robert W, Heathcock, Clayton H
Published in Journal of organic chemistry (30.06.2000)
Published in Journal of organic chemistry (30.06.2000)
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Stereoselective Total Synthesis of the Cyanobacterial Hepatotoxin 7-Epicylindrospermopsin: Revision of the Stereochemistry of Cylindrospermopsin
Heintzelman, Geoffrey R, Fang, Wen-Kui, Keen, Stephen P, Wallace, Grier A, Weinreb, Steven M
Published in Journal of the American Chemical Society (12.09.2001)
Published in Journal of the American Chemical Society (12.09.2001)
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NOVEL TRICYCLIC COMPOUNDS
WOLLER KEVIN R, FRANK KRISTINE E, ERICSSON ANNA M, VOSS JEFFREY W, FRIEDMAN MICHAEL, WISHART NEIL, MORYTKO MICHAEL J, CALDERWOOD DAVID J, FIAMENGO BRYAN A, WALLACE GRIER A, WANG LU, JOSEPHSOHN NATHAN S, ARGIRIADI MARIA A, GOEDKEN ERIC R, GEORGE DAWN M, LI BIQIN C, STEWART KENT D
Year of Publication 12.09.2018
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Year of Publication 12.09.2018
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Scalable Synthesis of ABBV-105 Enabled by Suzuki Coupling with Low Pd Loading, Ru-Catalyzed Asymmetric Hydrogenation, and Acylation Using Impinging Jet
Cardinal-David, Benoit, Shekhar, Shashank, Phillips, Eric M., Swift, Elizabeth C., Kotecki, Brian, Ickes, Andrew R., Storer, Gregory E., Caspi, Daniel D., Verma, Anuj, Moschetta, Eric G., Tao, Daniel, Morrill, Westin H., Bellettini, John R., Nordstrom, Fredrik L., Mattei, Alessandra, Springer, Kirsten, Qiu, Haixiao, Bien, Jeffrey T., Manjrekar, Onkar, Henry, Rodger F., Wallace, Grier A., Schaffter, Lisa, Voight, Eric A.
Published in Organic process research & development (16.08.2024)
Published in Organic process research & development (16.08.2024)
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NOVEL TRICYCLIC COMPOUNDS
WOLLER KEVIN R, FRANK KRISTINE E, ERICSSON ANNA M, VOSS JEFFREY W, FRIEDMAN MICHAEL, WISHART NEIL, MORYTKO MICHAEL J, CALDERWOOD DAVID J, FIAMENGO BRYAN A, WALLACE GRIER A, WANG LU, JOSEPHSOHN NATHAN S, ARGIRIADI MARIA A, GOEDKEN ERIC R, GEORGE DAWN M, LI BIQIN C, STEWART KENT D
Year of Publication 24.10.2017
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Year of Publication 24.10.2017
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Novel tricyclic compounds
WOLLER KEVIN R, FRANK KRISTINE E, ERICSSON ANNA M, VOSS JEFFREY W, FRIEDMAN MICHAEL, WISHART NEIL, MORYTKO MICHAEL J, CALDERWOOD DAVID J, FIAMENGO BRYAN A, WALLACE GRIER A, WANG LU, JOSEPHSOHN NATHAN S, ARGIRIADI MARIA A, GOEDKEN ERIC R, GEORGE DAWN M, LI BIQIN C, STEWART KENT D
Year of Publication 23.12.2016
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Year of Publication 23.12.2016
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PRIMARY CARBOXAMIDES AS BTK INHIBITORS
FRANK KRISTINE E, HOEMANN MICHAEL Z, WILSON NOEL S, OSUMA AUGUSTINE, SHEPPARD GEORGE, BONAFOUX DOMINIQUE, VAN CAMP JENNIFER, VAN EPPS STACY A, HUNTLEY RAYMOND, SOMAL GAGANDEEP K, XU XIANGDONG, WALLACE GRIER A, WANG LU, DAVIS HEATHER M, FRIEDMAN MICHAEL M, VASUDEVAN ANIL, HEROLD J. MARTIN, WANG ZHI
Year of Publication 08.03.2016
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Year of Publication 08.03.2016
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NOVEL TRICYCLIC COMPOUNDS
WOLLER KEVIN R, FRANK KRISTINE E, ERICSSON ANNA M, VOSS JEFFREY W, FRIEDMAN MICHAEL, WISHART NEIL, MORYTKO MICHAEL J, CALDERWOOD DAVID J, FIAMENGO BRYAN A, WALLACE GRIER A, WANG LU, JOSEPHSOHN NATHAN S, ARGIRIADI MARIA A, GOEDKEN ERIC R, GEORGE DAWN M, LI BIQIN C, STEWART KENT D
Year of Publication 06.02.2014
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Year of Publication 06.02.2014
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NOVEL TRICYCLIC COMPOUNDS
WOLLER KEVIN R, FRANK KRISTINE E, HOEMANN MICHAEL Z, ERICSSON ANNA M, VOSS JEFFREY W, FRIEDMAN MICHAEL, WISHART NEIL, MORYTKO MICHAEL J, CALDERWOOD DAVID J, FIAMENGO BRYAN A, WALLACE GRIER A, WANG LU, JOSEPHSOHN NATHAN S, ARGIRIADI MARIA A, GOEDKEN ERIC R, BREINLINGER ERIC C, GEORGE DAWN M, SOMAL GAGANDEEP, MULLEN KELLY D, LI BIQIN C, STEWART KENT D
Year of Publication 18.09.2012
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Year of Publication 18.09.2012
Patent
NOVEL TRICYCLIC COMPOUNDS
WOLLER KEVIN R, FRANK KRISTINE E, ERICSSON ANNA M, VOSS JEFFREY W, FRIEDMAN MICHAEL, WISHART NEIL, MORYTKO MICHAEL J, CALDERWOOD DAVID J, FIAMENGO BRYAN A, WALLACE GRIER A, WANG LU, JOSEPHSOHN NATHAN S, ARGIRIADI MARIA A, GOEDKEN ERIC R, GEORGE DAWN M, LI BIQIN C, STEWART KENT D
Year of Publication 21.02.2011
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Year of Publication 21.02.2011
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