Selumetinib in Children with Inoperable Plexiform Neurofibromas
Gross, Andrea M, Wolters, Pamela L, Dombi, Eva, Baldwin, Andrea, Whitcomb, Patricia, Fisher, Michael J, Weiss, Brian, Kim, AeRang, Bornhorst, Miriam, Shah, Amish C, Martin, Staci, Roderick, Marie C, Pichard, Dominique C, Carbonell, Amanda, Paul, Scott M, Therrien, Janet, Kapustina, Oxana, Heisey, Kara, Clapp, D. Wade, Zhang, Chi, Peer, Cody J, Figg, William D, Smith, Malcolm, Glod, John, Blakeley, Jaishri O, Steinberg, Seth M, Venzon, David J, Doyle, L. Austin, Widemann, Brigitte C
Published in The New England journal of medicine (09.04.2020)
Published in The New England journal of medicine (09.04.2020)
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Fanconi Anemia Proteins Function in Mitophagy and Immunity
Sumpter, Rhea, Sirasanagandla, Shyam, Fernández, Álvaro F., Wei, Yongjie, Dong, Xiaonan, Franco, Luis, Zou, Zhongju, Marchal, Christophe, Lee, Ming Yeh, Clapp, D. Wade, Hanenberg, Helmut, Levine, Beth
Published in Cell (05.05.2016)
Published in Cell (05.05.2016)
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Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis
Liao, Chung-Ping, Booker, Reid C, Brosseau, Jean-Philippe, Chen, Zhiguo, Mo, Juan, Tchegnon, Edem, Wang, Yong, Clapp, D Wade, Le, Lu Q
Published in The Journal of clinical investigation (02.07.2018)
Published in The Journal of clinical investigation (02.07.2018)
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Multicenter, Prospective, Phase II and Biomarker Study of High-Dose Bevacizumab as Induction Therapy in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannoma
Plotkin, Scott R, Duda, Dan G, Muzikansky, Alona, Allen, Jeffrey, Blakeley, Jaishri, Rosser, Tena, Campian, Jian L, Clapp, D Wade, Fisher, Michael J, Tonsgard, James, Ullrich, Nicole, Thomas, Coretta, Cutter, Gary, Korf, Bruce, Packer, Roger, Karajannis, Matthias A
Published in Journal of clinical oncology (10.12.2019)
Published in Journal of clinical oncology (10.12.2019)
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Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors
Bai, Ren-Yuan, Esposito, Dominic, Tam, Ada J., McCormick, Frank, Riggins, Gregory J., Wade Clapp, D., Staedtke, Verena
Published in Gene therapy (01.06.2019)
Published in Gene therapy (01.06.2019)
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Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial
Fisher, Michael J., Shih, Chie-Schin, Rhodes, Steven D., Armstrong, Amy E., Wolters, Pamela L., Dombi, Eva, Zhang, Chi, Angus, Steven P., Johnson, Gary L., Packer, Roger J., Allen, Jeffrey C., Ullrich, Nicole J., Goldman, Stewart, Gutmann, David H., Plotkin, Scott R., Rosser, Tena, Robertson, Kent A., Widemann, Brigitte C., Smith, Abbi E., Bessler, Waylan K., He, Yongzheng, Park, Su-Jung, Mund, Julie A., Jiang, Li, Bijangi-Vishehsaraei, Khadijeh, Robinson, Coretta Thomas, Cutter, Gary R., Korf, Bruce R., Blakeley, Jaishri O., Clapp, D. Wade
Published in Nature medicine (01.01.2021)
Published in Nature medicine (01.01.2021)
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Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase
Molosh, Andrei I, Johnson, Philip L, Spence, John P, Arendt, David, Federici, Lauren M, Bernabe, Cristian, Janasik, Steven P, Segu, Zaneer M, Khanna, Rajesh, Goswami, Chirayu, Zhu, Weiguo, Park, Su-Jung, Li, Lang, Mechref, Yehia S, Clapp, D Wade, Shekhar, Anantha
Published in Nature neuroscience (01.11.2014)
Published in Nature neuroscience (01.11.2014)
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A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies
Maertens, Ophélia, McCurrach, Mila E, Braun, Benjamin S, De Raedt, Thomas, Epstein, Inbal, Huang, Tannie Q, Lauchle, Jennifer O, Lee, Hyerim, Wu, Jianqiang, Cripe, Timothy P, Clapp, D Wade, Ratner, Nancy, Shannon, Kevin, Cichowski, Karen
Published in Cancer research (Chicago, Ill.) (01.11.2017)
Published in Cancer research (Chicago, Ill.) (01.11.2017)
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Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial
Robertson, Kent A, Dr, Nalepa, Grzegorz, MD, Yang, Feng-Chun, MD, Bowers, Daniel C, MD, Ho, Chang Y, MD, Hutchins, Gary D, Prof, Croop, James M, Prof, Vik, Terry A, MD, Denne, Scott C, Prof, Parada, Luis F, Prof, Hingtgen, Cynthia M, MD, Walsh, Laurence E, MD, Yu, Menggang, PhD, Pradhan, Kamnesh R, MD, Edwards-Brown, Mary K, Prof, Cohen, Mervyn D, Prof, Fletcher, James W, Prof, Travers, Jeffrey B, Prof, Staser, Karl W, PhD, Lee, Melissa W, BS, Sherman, Marcie R, BS, Davis, Cynthia J, RN, Miller, Lucy C, RN, Ingram, David A, Prof, Clapp, D Wade, Prof
Published in The lancet oncology (01.12.2012)
Published in The lancet oncology (01.12.2012)
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A molecular basis for neurofibroma-associated skeletal manifestations in NF1
Ma, Yun, Gross, Andrea M., Dombi, Eva, Pemov, Alexander, Choi, Kwangmin, Chaney, Katherine, Rhodes, Steven D., Angus, Steven P., Sciaky, Noah, Clapp, D. Wade, Ratner, Nancy, Widemann, Brigitte C., Rios, Jonathan J., Elefteriou, Florent
Published in Genetics in medicine (01.11.2020)
Published in Genetics in medicine (01.11.2020)
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PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2)
Hawley, Eric, Gehlhausen, Jeffrey, Karchugina, Sofiia, Chow, Hoi-Yee, Araiza-Olivera, Daniela, Radu, Maria, Smith, Abbi, Burks, Ciersten, Jiang, Li, Li, Xiaohong, Bessler, Waylan, Masters, Andrea, Edwards, Donna, Burgin, Callie, Jones, David, Yates, Charles, Clapp, D Wade, Chernoff, Jonathan, Park, Su-Jung
Published in Human molecular genetics (12.08.2021)
Published in Human molecular genetics (12.08.2021)
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Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1
Mund, Julie A, Park, SuJung, Smith, Abbi E, He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J, Mitchell, Dana K, Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K, Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D, Clapp, D Wade
Published in The Journal of biological chemistry (17.07.2020)
Published in The Journal of biological chemistry (17.07.2020)
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New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types
Gampala, Silpa, Moon, Hye-ran, Wireman, Randall, Peil, Jacqueline, Kiran, Sonia, Mitchell, Dana K., Brewster, Kylee, Mang, Henry, Masters, Andi, Bach, Christine, Smith-Kinnamen, Whitney, Doud, Emma H., Rai, Ratan, Mosley, Amber L., Quinney, Sara K., Clapp, D. Wade, Hamdouchi, Chafiq, Wikel, James, Zhang, Chi, Han, Bumsoo, Georgiadis, Millie M., Kelley, Mark R., Fishel, Melissa L.
Published in Pharmacological research (01.03.2024)
Published in Pharmacological research (01.03.2024)
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A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation
Gehlhausen, Jeffrey R, Park, Su-Jung, Hickox, Ann E, Shew, Matthew, Staser, Karl, Rhodes, Steven D, Menon, Keshav, Lajiness, Jacquelyn D, Mwanthi, Muithi, Yang, Xianlin, Yuan, Jin, Territo, Paul, Hutchins, Gary, Nalepa, Grzegorz, Yang, Feng-Chun, Conway, Simon J, Heinz, Michael G, Stemmer-Rachamimov, Anat, Yates, Charles W, Wade Clapp, D
Published in Human molecular genetics (01.01.2015)
Published in Human molecular genetics (01.01.2015)
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Fanconi anemia signaling network regulates the spindle assembly checkpoint
Nalepa, Grzegorz, Enzor, Rikki, Sun, Zejin, Marchal, Christophe, Park, Su-Jung, Yang, Yanzhu, Tedeschi, Laura, Kelich, Stephanie, Hanenberg, Helmut, Clapp, D Wade
Published in The Journal of clinical investigation (01.09.2013)
Published in The Journal of clinical investigation (01.09.2013)
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p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics
Allen, Jayme D., Jaffer, Zahara M., Park, Su-Jung, Burgin, Sarah, Hofmann, Clemens, Sells, Mary Ann, Chen, Shi, Derr-Yellin, Ethel, Michels, Elizabeth G., McDaniel, Andrew, Bessler, Waylan K., Ingram, David A., Atkinson, Simon J., Travers, Jeffrey B., Chernoff, Jonathan, Clapp, D. Wade
Published in Blood (19.03.2009)
Published in Blood (19.03.2009)
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