Attenuation of initial pilocarpine‐induced electrographic seizures by methionine sulfoximine pretreatment tightly correlates with the reduction of extracellular taurine in the hippocampus
Pawlik, Marek, Czarnecka, Anna Maria, Kołodziej, Marcin, Skowrońska, Katarzyna, Węgrzynowicz, Michał, Podgajna, Martyna, Czuczwar, Stanisław Jerzy, Albrecht, Jan
Published in Epilepsia (Copenhagen) (01.05.2023)
Published in Epilepsia (Copenhagen) (01.05.2023)
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Direct Exposure to Ammonia and Hyperammonemia Increase the Extracellular Accumulation and Degradation of Astroglia-Derived Glutathione in the Rat Prefrontal Cortex
Hilgier, Wojciech, Węgrzynowicz, Michał, Ruszkiewicz, Joanna, Oja, Simo S., Saransaari, Pirjo, Albrecht, Jan
Published in Toxicological sciences (01.09.2010)
Published in Toxicological sciences (01.09.2010)
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Mechanisms of ammonia-induced cell death in rat cortical neurons: Roles of NMDA receptors and glutathione
Klejman, Agata, Węgrzynowicz, Michał, Szatmari, Erzsebet M., Mioduszewska, Barbara, Hetman, Michał, Albrecht, Jan
Published in Neurochemistry international (01.07.2005)
Published in Neurochemistry international (01.07.2005)
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Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: The role of cystine uptake
Węgrzynowicz, Michał, Hilgier, Wojciech, Dybel, Anna, Oja, Simo S., Saransaari, Pirjo, Albrecht, Jan
Published in Neurochemistry international (01.06.2007)
Published in Neurochemistry international (01.06.2007)
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Salivary α‐Synuclein RT‐QuIC Correlates with Disease Severity in de novo Parkinson's Disease
Vivacqua, Giorgio, Mason, Matthew, De Bartolo, Maria Ilenia, Węgrzynowicz, Michal, Calò, Laura, Belvisi, Daniele, Suppa, Antonio, Fabbrini, Giovanni, Berardelli, Alfredo, Spillantini, MariaGrazia
Published in Movement disorders (01.01.2023)
Published in Movement disorders (01.01.2023)
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Endogenous neuroprotectants in ammonia toxicity in the central nervous system : Facts and hypotheses
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Conference Proceeding
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Role of astrocytes in brain function and disease
Sidoryk-Wegrzynowicz, Marta, Wegrzynowicz, Michal, Lee, Eunsook, Bowman, Aaron B, Aschner, Michael
Published in Toxicologic pathology (01.01.2011)
Published in Toxicologic pathology (01.01.2011)
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L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils
Migdalska-Richards, Anna, Wegrzynowicz, Michal, Harrison, Ian F, Verona, Guglielmo, Bellotti, Vittorio, Spillantini, Maria Grazia, Schapira, Anthony H V
Published in PloS one (24.08.2020)
Published in PloS one (24.08.2020)
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Effect of Glutamine Synthesis Inhibition with Methionine Sulfoximine on the Nitric Oxide–Cyclic GMP Pathway in the Rat Striatum Treated Acutely with Ammonia: A Microdialysis Study
Hilgier, Wojciech, Węgrzynowicz, Michal, Mączewski, Michal, Beręsewicz, Andrzej, Oja, Simo S., Saransaari, Pirjo, Albrecht, Jan
Published in Neurochemical research (01.02.2008)
Published in Neurochemical research (01.02.2008)
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Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial
Levin, Johannes, Sing, Nand, Melbourne, Sue, Morgan, Amber, Mariner, Carla, Spillantini, Maria Grazia, Wegrzynowicz, Michal, Dalley, Jeffrey W., Langer, Simon, Ryazanov, Sergey, Leonov, Andrei, Griesinger, Christian, Schmidt, Felix, Weckbecker, Daniel, Prager, Kai, Matthias, Torsten, Giese, Armin
Published in EBioMedicine (01.06.2022)
Published in EBioMedicine (01.06.2022)
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Potent but transient immunosuppression of T-cells is a general feature of CD71 + erythroid cells
Grzywa, Tomasz M, Sosnowska, Anna, Rydzynska, Zuzanna, Lazniewski, Michal, Plewczynski, Dariusz, Klicka, Klaudia, Malecka-Gieldowska, Milena, Rodziewicz-Lurzynska, Anna, Ciepiela, Olga, Justyniarska, Magdalena, Pomper, Paulina, Grzybowski, Marcin M, Blaszczyk, Roman, Wegrzynowicz, Michal, Tomaszewska, Agnieszka, Basak, Grzegorz, Golab, Jakub, Nowis, Dominika
Published in Communications biology (10.12.2021)
Published in Communications biology (10.12.2021)
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Cyclic GMP in blood and minimal hepatic encephalopathy : fine-tuning of the diagnosis
ALBRECHT, J, WIGRZYNOWICZ, M
Published in Journal of molecular medicine (Berlin, Germany) (01.03.2007)
Published in Journal of molecular medicine (Berlin, Germany) (01.03.2007)
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Synaptic failure and α-synuclein
Calo, Laura, Wegrzynowicz, Michal, Santivañez-Perez, Jessica, Grazia Spillantini, Maria
Published in Movement disorders (01.02.2016)
Published in Movement disorders (01.02.2016)
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Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model
Wegrzynowicz, Michal, Bar-On, Dana, Calo’, Laura, Anichtchik, Oleg, Iovino, Mariangela, Xia, Jing, Ryazanov, Sergey, Leonov, Andrei, Giese, Armin, Dalley, Jeffrey W., Griesinger, Christian, Ashery, Uri, Spillantini, Maria Grazia
Published in Acta neuropathologica (01.10.2019)
Published in Acta neuropathologica (01.10.2019)
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The L444P Gba1 mutation enhances alpha-synuclein induced loss of nigral dopaminergic neurons in mice
Migdalska-Richards, Anna, Wegrzynowicz, Michal, Rusconi, Raffaella, Deangeli, Giulio, Di Monte, Donato A, Spillantini, Maria G, Schapira, Anthony H V
Published in Brain (London, England : 1878) (01.10.2017)
Published in Brain (London, England : 1878) (01.10.2017)
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CSPα reduces aggregates and rescues striatal dopamine release in α-synuclein transgenic mice
Caló, Laura, Hidari, Eric, Wegrzynowicz, Michal, Dalley, Jeffrey W, Schneider, Bernard L, Podgajna, Martyna, Anichtchik, Oleg, Carlson, Emma, Klenerman, David, Spillantini, Maria Grazia
Published in Brain (London, England : 1878) (28.07.2021)
Published in Brain (London, England : 1878) (28.07.2021)
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L444P Gba1 mutation increases formation and spread of [alpha]-synuclein deposits in mice injected with mouse [alpha]-synuclein pre-formed fibrils
Migdalska-Richards, Anna, Wegrzynowicz, Michal, Harrison, Ian F, Verona, Guglielmo, Bellotti, Vittorio, Spillantini, Maria Grazia, Schapira, Anthony H.V
Published in PloS one (24.08.2020)
Published in PloS one (24.08.2020)
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