Adenosine A2A Receptor (A2AAR) Ligand Screening Using the 19F‑NMR Probe FPPA
Zhang, Jinfeng, Feng, Dandan, Cheng, Jianjun, Wüthrich, Kurt
Published in Journal of the American Chemical Society (19.07.2023)
Published in Journal of the American Chemical Society (19.07.2023)
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Journal Article
The GPCR Network: a large-scale collaboration to determine human GPCR structure and function
Stevens, Raymond C., Cherezov, Vadim, Katritch, Vsevolod, Abagyan, Ruben, Kuhn, Peter, Rosen, Hugh, Wüthrich, Kurt
Published in Nature reviews. Drug discovery (01.01.2013)
Published in Nature reviews. Drug discovery (01.01.2013)
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Journal Article
Book Review
Two-Dimensional NMR Spectroscopy of the G Protein-Coupled Receptor A2AAR in Lipid Nanodiscs
Guo, Canyong, Yang, Lingyun, Liu, Zhijun, Liu, Dongsheng, Wüthrich, Kurt
Published in Molecules (Basel, Switzerland) (14.07.2023)
Published in Molecules (Basel, Switzerland) (14.07.2023)
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Journal Article
Splicing Site Recognition by Synergy of Three Domains in Splicing Factor RBM10
Serrano, Pedro, Hammond, John A, Geralt, Michael, Wüthrich, Kurt
Published in Biochemistry (Easton) (13.03.2018)
Published in Biochemistry (Easton) (13.03.2018)
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Journal Article
Proteomics Analysis Unravels the Functional Repertoire of Coronavirus Nonstructural Protein 3
NEUMAN, Benjamin W, JOSEPH, Jeremiah S, STEVENS, Raymond C, BUCHMEIER, Michael J, KUHN, Peter, SAIKATENDU, Kumar S, SERRANO, Pedro, CHATTERJEE, Amarnath, JOHNSON, Margaret A, LUJIAN LIAO, KLAUS, Joseph P, YATES, John R, WUTHRICH, Kurt
Published in Journal of Virology (01.06.2008)
Published in Journal of Virology (01.06.2008)
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Journal Article
Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor
Eddy, Matthew T., Lee, Ming-Yue, Gao, Zhan-Guo, White, Kate L., Didenko, Tatiana, Horst, Reto, Audet, Martin, Stanczak, Pawel, McClary, Kyle M., Han, Gye Won, Jacobson, Kenneth A., Stevens, Raymond C., Wüthrich, Kurt
Published in Cell (11.01.2018)
Published in Cell (11.01.2018)
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Journal Article
Automated Projection Spectroscopy (APSY)
Hiller, Sebastian, Fiorito, Francesco, Wüthrich, Kurt, Wider, Gerhard
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2005)
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Journal Article
GPCR structural characterization by NMR spectroscopy in solution
Yang, Lingyun, Liu, Dongsheng, Wüthrich, Kurt
Published in Acta biochimica et biophysica Sinica (01.09.2022)
Published in Acta biochimica et biophysica Sinica (01.09.2022)
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Journal Article
Novel β-Barrel Fold in the Nuclear Magnetic Resonance Structure of the Replicase Nonstructural Protein 1 from the Severe Acute Respiratory Syndrome Coronavirus
ALMEIDA, Marcius S, JOHNSON, Margaret A, HERRMANN, Torsten, GERALT, Michael, WÜTHRICH, Kurt
Published in Journal of Virology (01.04.2007)
Published in Journal of Virology (01.04.2007)
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Journal Article
NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor
O’Connor, Casey, White, Kate L., Doncescu, Nathalie, Didenko, Tatiana, Roth, Bryan L., Czaplicki, Georges, Stevens, Raymond C., Wüthrich, Kurt, Milon, Alain
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2015)
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Journal Article
An EB1-Binding Motif Acts as a Microtubule Tip Localization Signal
Honnappa, Srinivas, Gouveia, Susana Montenegro, Weisbrich, Anke, Damberger, Fred F., Bhavesh, Neel S., Jawhari, Hatim, Grigoriev, Ilya, van Rijssel, Frederik J.A., Buey, Ruben M., Lawera, Aleksandra, Jelesarov, Ilian, Winkler, Fritz K., Wüthrich, Kurt, Akhmanova, Anna, Steinmetz, Michel O.
Published in Cell (23.07.2009)
Published in Cell (23.07.2009)
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Journal Article
Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β₂AR
Lamichhane, Rajan, Liu, Jeffrey J., Pljevaljcic, Goran, White, Kate L., van der Schans, Edwin, Katritch, Vsevolod, Stevens, Raymond C., Wüthrich, Kurt, Millar, David P.
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2015)
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Journal Article
In-Membrane Chemical Modification (IMCM) for Site-Specific Chromophore Labeling of GPCRs
Sušac, Lukas, O'Connor, Casey, Stevens, Raymond C., Wüthrich, Kurt
Published in Angewandte Chemie International Edition (07.12.2015)
Published in Angewandte Chemie International Edition (07.12.2015)
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Journal Article
G Protein-coupled Receptor (GPCR) Reconstitution and Labeling for Solution Nuclear Magnetic Resonance (NMR) Studies of the Structural Basis of Transmembrane Signaling
Ge, Haoyi, Wang, Huixia, Pan, Benxun, Feng, Dandan, Guo, Canyong, Yang, Lingyun, Liu, Dongsheng, Wüthrich, Kurt
Published in Molecules (Basel, Switzerland) (20.04.2022)
Published in Molecules (Basel, Switzerland) (20.04.2022)
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Journal Article
Tumor Immunotherapy Using A2A Adenosine Receptor Antagonists
Zhang, Jinfeng, Yan, Wenzhong, Duan, Wenwen, Wüthrich, Kurt, Cheng, Jianjun
Published in Pharmaceuticals (Basel, Switzerland) (08.09.2020)
Published in Pharmaceuticals (Basel, Switzerland) (08.09.2020)
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Journal Article
Attenuated T2 relaxation by mutual cancellation of dipole–dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution
Pervushin, K, Riek, R, Wider, G, Wüthrich, K
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.1997)
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Journal Article