Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking
Hellmuth, Klaus, Grosskopf, Stefanie, Lum, Ching Tung, Würtele, Martin, Röder, Nadine, von Kries, Jens Peter, Rosario, Marta, Rademann, Jörg, Birchmeier, Walter
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2008)
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Journal Article
Biochemical screening for SARS-CoV-2 main protease inhibitors
Coelho, Camila, Gallo, Gloria, Campos, Claudia B, Hardy, Leon, Würtele, Martin
Published in PloS one (06.10.2020)
Published in PloS one (06.10.2020)
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Journal Article
Biochemical characterization of a protein tyrosine phosphatase from Trypanosoma cruzi involved in metacyclogenesis and cell invasion
Gallo, Gloria, Ramos, Thiago Cesar Prata, Tavares, Fernanda, Rocha, Antonio A., Machi, Emerson, Schenkman, Sergio, Bahia, Diana, Pesquero, João Bosco, Würtele, Martin
Published in Biochemical and biophysical research communications (13.05.2011)
Published in Biochemical and biophysical research communications (13.05.2011)
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Journal Article
Dynamic cross correlation analysis of Thermus thermophilus alkaline phosphatase and determinants of thermostability
Borges, Bruno, Gallo, Gloria, Coelho, Camila, Negri, Naiane, Maiello, Fernando, Hardy, Leon, Würtele, Martin
Published in Biochimica et biophysica acta. General subjects (01.07.2021)
Published in Biochimica et biophysica acta. General subjects (01.07.2021)
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Journal Article
Biochemical Screening of Potent Zika Virus Protease Inhibitors
Coelho, Camila, Gallo, Gloria, Hardy, Leon, Bottazzi, Maria Elena, Campos, Claudia, Würtele, Martin
Published in ChemMedChem (20.04.2022)
Published in ChemMedChem (20.04.2022)
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Journal Article
Boophilin D1, a Kunitz type protease inhibitor, as a source of inhibitors for the ZIKA virus NS2B-NS3 protease
Manzato, Veronica de Moraes, Di Santo, Camila, Torquato, Ricardo Jose Soares, Coelho, Camila, Gallo, Gloria, Hardy, Leon, Würtele, Martin, Tanaka, Aparecida Sadae
Published in Biochimie (01.11.2023)
Published in Biochimie (01.11.2023)
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Journal Article
Identification of an ex vivo inhibitor of the schizophrenia biomarker Ndel1 by high throughput screening
Nani, João V., Coelho, Camila, Oyadomari, William Y., Santiago, Thays Calista, Machado, Marcelo Marcondes, Christoff, Raissa R., Garcez, Patrícia P., Oliveira, Vitor, Würtele, Martin, Hayashi, Mirian A.F.
Published in Biochemical pharmacology (01.11.2023)
Published in Biochemical pharmacology (01.11.2023)
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Journal Article
Structural view of a fungal toxin acting on a 14-3-3 regulatory complex
Würtele, Martin, Jelich-Ottmann, Christian, Wittinghofer, Alfred, Oecking, Claudia
Published in The EMBO journal (03.03.2003)
Published in The EMBO journal (03.03.2003)
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Journal Article
A proteomics-MM/PBSA dual approach for the analysis of SARS-CoV-2 main protease substrate peptide specificity
Gallo, Gloria, Barcick, Uilla, Coelho, Camila, Salardani, Murilo, Camacho, Maurício F., Cajado-Carvalho, Daniela, Loures, Flávio V., Serrano, Solange M.T., Hardy, Leon, Zelanis, André, Würtele, Martin
Published in Peptides (New York, N.Y. : 1980) (01.08.2022)
Published in Peptides (New York, N.Y. : 1980) (01.08.2022)
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Journal Article
Structure of the ExoS GTPase activating domain
Würtele, Martin, Renault, Louis, Barbieri, Joseph T., Wittinghofer, Alfred, Wolf, Eva
Published in FEBS letters (23.02.2001)
Published in FEBS letters (23.02.2001)
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Journal Article
Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β
Behrens, Jurgen, Jerchow, Boris-Alexander, Wurtele, Martin, Grimm, Jan, Asbrand, Christian, Wirtz, Ralph, Kuhl, Michael, Wedlich, Doris, Birchmeier, Walter
Published in Science (American Association for the Advancement of Science) (24.04.1998)
Published in Science (American Association for the Advancement of Science) (24.04.1998)
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Journal Article
Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis
Pinto, Silas, Sato, Vitor N., De-Souza, Evandro A., Ferraz, Rafael C., Camara, Henrique, Pinca, Ana Paula F., Mazzotti, Diego R., Lovci, Michael T., Tonon, Guilherme, Lopes-Ramos, Camila M., Parmigiani, Raphael B., Wurtele, Martin, Massirer, Katlin B., Mori, Marcelo A.
Published in Redox biology (01.09.2018)
Published in Redox biology (01.09.2018)
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Journal Article
Inhibition of the SARS-CoV-2 Main Protease by Isoquercitrin γ-Cyclodextrin Inclusion Complex Formulations: A Biochemical and In Silico Study
Wurtele, Martin, Coelho, Camila, Gallo, Gloria, Campos, Claudia, Hardy, Leon, Perez Castillo, Yunierkis, Moriwaki, Masamitsu, Kapoor, Mahendra P., de Sousa, Damião Pergentino
Published in Journal of chemistry (24.04.2023)
Published in Journal of chemistry (24.04.2023)
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Journal Article
Bradykinin inhibits hepatic gluconeogenesis in obese mice
Barros, Carlos Castilho, Haro, Anderson, Russo, Fernanda Jaqueline, Schadock, Ines, Almeida, Sandro Soares, Reis, Felipe Castellani, Moraes, Milton Rocha, Haidar, Andre, Hirata, Aparecida Emiko, Mori, Marcelo, Bacurau, Reury Frank Pereira, Würtele, Martin, Bader, Michael, Pesquero, Joao Bosco, Araujo, Ronaldo Carvalho
Published in Laboratory investigation (01.10.2012)
Published in Laboratory investigation (01.10.2012)
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Journal Article
Purification, crystallization, crystallographic analysis and phasing of the CRISPR-associated protein Csm2 from Thermotoga maritima
Gallo, Gloria, Augusto, Gilles, Rangel, Giulliana, Zelanis, André, Mori, Marcelo A., Barbosa Campos, Cláudia, Würtele, Martin
Published in Acta crystallographica. Section F, Structural biology communications (01.10.2015)
Published in Acta crystallographica. Section F, Structural biology communications (01.10.2015)
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Journal Article
The genome sequence of Leishmania (Leishmania) amazonensis: functional annotation and extended analysis of gene models
Real, Fernando, Vidal, Ramon Oliveira, Carazzolle, Marcelo Falsarella, Mondego, Jorge Maurício Costa, Costa, Gustavo Gilson Lacerda, Herai, Roberto Hirochi, Würtele, Martin, de Carvalho, Lucas Miguel, Carmona e Ferreira, Renata, Mortara, Renato Arruda, Barbiéri, Clara Lucia, Mieczkowski, Piotr, da Silveira, José Franco, Briones, Marcelo Ribeiro da Silva, Pereira, Gonçalo Amarante Guimarães, Bahia, Diana
Published in DNA research (01.12.2013)
Published in DNA research (01.12.2013)
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