Genetic advances in systemic lupus erythematosus: an update
Chen, Lingyan, Morris, David L, Vyse, Timothy J
Published in Current opinion in rheumatology (01.09.2017)
Published in Current opinion in rheumatology (01.09.2017)
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Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups
Wang, Yong-Fei, Zhang, Yan, Lin, Zhiming, Zhang, Huoru, Wang, Ting-You, Cao, Yujie, Morris, David L, Sheng, Yujun, Yin, Xianyong, Zhong, Shi-Long, Gu, Xiaoqiong, Lei, Yao, He, Jing, Wu, Qi, Shen, Jiangshan Jane, Yang, Jing, Lam, Tai-Hing, Lin, Jia-Huang, Mai, Zhi-Ming, Guo, Mengbiao, Tang, Yuanjia, Chen, Yanhui, Song, Qin, Ban, Bo, Mok, Chi Chiu, Cui, Yong, Lu, Liangjing, Shen, Nan, Sham, Pak C, Lau, Chak Sing, Smith, David K, Vyse, Timothy J, Zhang, Xuejun, Lau, Yu Lung, Yang, Wanling
Published in Nature communications (03.02.2021)
Published in Nature communications (03.02.2021)
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Autophagy is activated in systemic lupus erythematosus and required for plasmablast development
Clarke, Alexander J, Ellinghaus, Ursula, Cortini, Andrea, Stranks, Amanda, Simon, Anna Katharina, Botto, Marina, Vyse, Timothy J
Published in Annals of the rheumatic diseases (01.05.2015)
Published in Annals of the rheumatic diseases (01.05.2015)
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Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells
Halim, Timotheus Y.F., Rana, Batika M.J., Walker, Jennifer A., Kerscher, Bernhard, Knolle, Martin D., Jolin, Helen E., Serrao, Eva M., Haim-Vilmovsky, Liora, Teichmann, Sarah A., Rodewald, Hans-Reimer, Botto, Marina, Vyse, Timothy J., Fallon, Padraic G., Li, Zhi, Withers, David R., McKenzie, Andrew N.J.
Published in Immunity (Cambridge, Mass.) (19.06.2018)
Published in Immunity (Cambridge, Mass.) (19.06.2018)
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COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection
Wang, Yuxuan, Guga, Suri, Wu, Kejia, Khaw, Zoe, Tzoumkas, Konstantinos, Tombleson, Phil, Comeau, Mary E, Langefeld, Carl D, Cunninghame Graham, Deborah S, Morris, David L, Vyse, Timothy J
Published in PLoS genetics (03.11.2022)
Published in PLoS genetics (03.11.2022)
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C-reactive protein in rheumatology: biology and genetics
Rhodes, Benjamin, Fürnrohr, Barbara G, Vyse, Timothy J
Published in Nature reviews. Rheumatology (01.05.2011)
Published in Nature reviews. Rheumatology (01.05.2011)
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Defining the role of the MHC in autoimmunity: a review and pooled analysis
Fernando, Michelle M A, Stevens, Christine R, Walsh, Emily C, De Jager, Philip L, Goyette, Philippe, Plenge, Robert M, Vyse, Timothy J, Rioux, John D
Published in PLoS genetics (01.04.2008)
Published in PLoS genetics (01.04.2008)
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Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus
Cunninghame Graham, Deborah S, Morris, David L, Bhangale, Tushar R, Criswell, Lindsey A, Syvänen, Ann-Christine, Rönnblom, Lars, Behrens, Timothy W, Graham, Robert R, Vyse, Timothy J
Published in PLoS genetics (01.10.2011)
Published in PLoS genetics (01.10.2011)
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UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases
Lewis, Myles J., Vyse, Simon, Shields, Adrian M., Boeltz, Sebastian, Gordon, Patrick A., Spector, Timothy D., Lehner, Paul J., Walczak, Henning, Vyse, Timothy J.
Published in American journal of human genetics (05.02.2015)
Published in American journal of human genetics (05.02.2015)
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Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at IKZF1 and IKZF3 in Systemic Lupus Erythematosus
Vyse, Timothy J, Cunninghame Graham, Deborah S
Published in International journal of molecular sciences (09.11.2020)
Published in International journal of molecular sciences (09.11.2020)
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Autoantibodies targeting TLR and SMAD pathways define new subgroups in systemic lupus erythematosus
Lewis, Myles J., McAndrew, Michael B., Wheeler, Colin, Workman, Nicholas, Agashe, Pooja, Koopmann, Jens, Uddin, Ezam, Morris, David L., Zou, Lu, Stark, Richard, Anson, John, Cope, Andrew P., Vyse, Timothy J.
Published in Journal of autoimmunity (01.07.2018)
Published in Journal of autoimmunity (01.07.2018)
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The genetics of lupus: a functional perspective
Guerra, Sandra G, Vyse, Timothy J, Cunninghame Graham, Deborah S
Published in Arthritis research & therapy (01.01.2012)
Published in Arthritis research & therapy (01.01.2012)
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Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans
Lessard, Christopher J., Sajuthi, Satria, Zhao, Jian, Kim, Kwangwoo, Ice, John A., Li, He, Ainsworth, Hannah, Rasmussen, Astrid, Kelly, Jennifer A., Marion, Miranda, Bang, So‐Young, Bin Joo, Young, Choi, Jeongim, Lee, Hye‐Soon, Mo Kang, Young, Suh, Chang‐Hee, Tae Chung, Won, Lee, Soo‐Kon, Choe, Jung‐Yoon, Cheol Shim, Seung, Hee Oh, Ji, Jin Kim, Young, Han, Bok‐Ghee, Shen, Nan, Siew Howe, Hwee, Wakeland, Edward K., Li, Quan‐Zhen, Wook Song, Yeong, Gaffney, Patrick M., Alarcón‐Riquelme, Marta E., Criswell, Lindsey A., Jacob, Chaim O., Kimberly, Robert P., Vyse, Timothy J., Harley, John B., Sivils, Kathy L., Bae, Sang‐Cheol, Langefeld, Carl D., Tsao, Betty P.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2016)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2016)
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Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase
Jacob, Chaim O, Eisenstein, Miriam, Dinauer, Mary C, Ming, Wenyu, Liu, Qiang, John, Sutha, Quismorio, Francesco P., Jr, Reiff, Andreas, Myones, Barry L, Kaufman, Kenneth M, McCurdy, Deborah, Harley, John B, Silverman, Earl, Kimberly, Robert P, Vyse, Timothy J, Gaffney, Patrick M, Moser, Kathy L, Klein-Gitelman, Marisa, Wagner-Weiner, Linda, Langefeld, Carl D, Armstrong, Don L, Zidovetzki, Raphael
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2012)
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Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression
Hauberg, Mads Engel, Zhang, Wen, Giambartolomei, Claudia, Franzén, Oscar, Morris, David L., Vyse, Timothy J., Ruusalepp, Arno, Fromer, Menachem, Sieberts, Solveig K., Johnson, Jessica S., Ruderfer, Douglas M., Shah, Hardik R., Klei, Lambertus L., Dang, Kristen K., Perumal, Thanneer M., Logsdon, Benjamin A., Mahajan, Milind C., Mangravite, Lara M., Essioux, Laurent, Toyoshiba, Hiroyoshi, Gur, Raquel E., Hahn, Chang-Gyu, Lewis, David A., Haroutunian, Vahram, Peters, Mette A., Lipska, Barbara K., Buxbaum, Joseph D., Hirai, Keisuke, Domenici, Enrico, Devlin, Bernie, Sklar, Pamela, Schadt, Eric E., Björkegren, Johan L.M., Roussos, Panos
Published in American journal of human genetics (01.06.2017)
Published in American journal of human genetics (01.06.2017)
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A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap
Ramos, Paula S, Criswell, Lindsey A, Moser, Kathy L, Comeau, Mary E, Williams, Adrienne H, Pajewski, Nicholas M, Chung, Sharon A, Graham, Robert R, Zidovetzki, Raphael, Kelly, Jennifer A, Kaufman, Kenneth M, Jacob, Chaim O, Vyse, Timothy J, Tsao, Betty P, Kimberly, Robert P, Gaffney, Patrick M, Alarcón-Riquelme, Marta E, Harley, John B, Langefeld, Carl D
Published in PLoS genetics (01.12.2011)
Published in PLoS genetics (01.12.2011)
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defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus
Willcocks, Lisa C, Carr, Edward J, Niederer, Heather A, Rayner, Tim F, Williams, Thomas N, Yang, Wanling, Scott, J. Anthony G, Urban, Britta C, Peshu, Norbert, Vyse, Timothy J, Lau, Yu Lung, Lyons, Paul A, Smith, Kenneth G.C
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2010)
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Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans
Domin, Jan, Mangion, Jonathan, Cook, H. Terence, Petretto, Enrico, Vyse, Timothy J, Flint, Jonathan, Johnson, Michelle D, Patel, Sheetal G, Pusey, Charles D, Cook, Paul R, Evans, David J, Duda, Mark, Smith, Jennifer, Dong, Rong, Bhangal, Gurjeet, Aitman, Timothy J, Roberton-Lowe, Cheri, Sheehan-Rooney, Kelly, Marshall, Amy J, Boyle, Joseph J, Norsworthy, Penny J, Hodges, Matthew D
Published in Nature (16.02.2006)
Published in Nature (16.02.2006)
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