Comparability of mixed IC₅₀ data - a statistical analysis
Kalliokoski, Tuomo, Kramer, Christian, Vulpetti, Anna, Gedeck, Peter
Published in PloS one (16.04.2013)
Published in PloS one (16.04.2013)
Get full text
Journal Article
Fluorine NMR functional screening: from purified enzymes to human intact living cells
Dalvit, Claudio, Veronesi, Marina, Vulpetti, Anna
Published in Journal of biomolecular NMR (01.11.2020)
Published in Journal of biomolecular NMR (01.11.2020)
Get full text
Journal Article
Fluorine as a Hydrogen-Bond Acceptor: Experimental Evidence and Computational Calculations
Dalvit, Claudio, Invernizzi, Christian, Vulpetti, Anna
Published in Chemistry : a European journal (25.08.2014)
Published in Chemistry : a European journal (25.08.2014)
Get full text
Journal Article
Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase
Angst, Daniela, Gessier, François, Janser, Philipp, Vulpetti, Anna, Wälchli, Rudolf, Beerli, Christian, Littlewood-Evans, Amanda, Dawson, Janet, Nuesslein-Hildesheim, Barbara, Wieczorek, Grazyna, Gutmann, Sascha, Scheufler, Clemens, Hinniger, Alexandra, Zimmerlin, Alfred, Funhoff, Enrico G, Pulz, Robert, Cenni, Bruno
Published in Journal of medicinal chemistry (28.05.2020)
Published in Journal of medicinal chemistry (28.05.2020)
Get full text
Journal Article
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance
Schröder, Martin, Renatus, Martin, Liang, Xiaoyou, Meili, Fabian, Zoller, Thomas, Ferrand, Sandrine, Gauter, Francois, Li, Xiaoyan, Sigoillot, Frederic, Gleim, Scott, Stachyra, Therese-Marie, Thomas, Jason R., Begue, Damien, Khoshouei, Maryam, Lefeuvre, Peggy, Andraos-Rey, Rita, Chung, BoYee, Ma, Renate, Pinch, Benika, Hofmann, Andreas, Schirle, Markus, Schmiedeberg, Niko, Imbach, Patricia, Gorses, Delphine, Calkins, Keith, Bauer-Probst, Beatrice, Maschlej, Magdalena, Niederst, Matt, Maher, Rob, Henault, Martin, Alford, John, Ahrne, Erik, Tordella, Luca, Hollingworth, Greg, Thomä, Nicolas H., Vulpetti, Anna, Radimerski, Thomas, Holzer, Philipp, Carbonneau, Seth, Thoma, Claudio R.
Published in Nature communications (04.01.2024)
Published in Nature communications (04.01.2024)
Get full text
Journal Article
Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β
Hommel, Ulrich, Hurth, Konstanze, Rondeau, Jean-Michel, Vulpetti, Anna, Ostermeier, Daniela, Boettcher, Andreas, Brady, Jacob Peter, Hediger, Michael, Lehmann, Sylvie, Koch, Elke, Blechschmidt, Anke, Yamamoto, Rina, Tundo Dottorello, Valentina, Haenni-Holzinger, Sandra, Kaiser, Christian, Lehr, Philipp, Lingel, Andreas, Mureddu, Luca, Schleberger, Christian, Blank, Jutta, Ramage, Paul, Freuler, Felix, Eder, Joerg, Bornancin, Frédéric
Published in Nature communications (07.09.2023)
Published in Nature communications (07.09.2023)
Get full text
Journal Article
Author Correction: DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance
Schröder, Martin, Renatus, Martin, Liang, Xiaoyou, Meili, Fabian, Zoller, Thomas, Ferrand, Sandrine, Gauter, Francois, Li, Xiaoyan, Sigoillot, Frederic, Gleim, Scott, Stachyra, Therese-Marie, Thomas, Jason R., Begue, Damien, Khoshouei, Maryam, Lefeuvre, Peggy, Andraos-Rey, Rita, Chung, BoYee, Ma, Renate, Pinch, Benika, Hofmann, Andreas, Schirle, Markus, Schmiedeberg, Niko, Imbach, Patricia, Gorses, Delphine, Calkins, Keith, Bauer-Probst, Beatrice, Maschlej, Magdalena, Niederst, Matt, Maher, Rob, Henault, Martin, Alford, John, Ahrne, Erik, Tordella, Luca, Hollingworth, Greg, Thomä, Nicolas H., Vulpetti, Anna, Radimerski, Thomas, Holzer, Philipp, Carbonneau, Seth, Thoma, Claudio R.
Published in Nature communications (19.08.2024)
Published in Nature communications (19.08.2024)
Get full text
Journal Article
Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors
Vulpetti, Anna, Randl, Stefan, Rüdisser, Simon, Ostermann, Nils, Erbel, Paul, Mac Sweeney, Aengus, Zoller, Thomas, Salem, Bahaa, Gerhartz, Bernd, Cumin, Frederic, Hommel, Ulrich, Dalvit, Claudio, Lorthiois, Edwige, Maibaum, Jürgen
Published in Journal of medicinal chemistry (09.03.2017)
Published in Journal of medicinal chemistry (09.03.2017)
Get full text
Journal Article
Combined use of computational chemistry, NMR screening, and X-ray crystallography for identification and characterization of fluorophilic protein environments
Vulpetti, Anna, Schiering, Nikolaus, Dalvit, Claudio
Published in Proteins, structure, function, and bioinformatics (01.12.2010)
Published in Proteins, structure, function, and bioinformatics (01.12.2010)
Get full text
Journal Article
Optimization of 6,6-dimethyl pyrrolo[3,4- c]pyrazoles: Identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing
Brasca, Maria Gabriella, Albanese, Clara, Alzani, Rachele, Amici, Raffaella, Avanzi, Nilla, Ballinari, Dario, Bischoff, James, Borghi, Daniela, Casale, Elena, Croci, Valter, Fiorentini, Francesco, Isacchi, Antonella, Mercurio, Ciro, Nesi, Marcella, Orsini, Paolo, Pastori, Wilma, Pesenti, Enrico, Pevarello, Paolo, Roussel, Patrick, Varasi, Mario, Volpi, Daniele, Vulpetti, Anna, Ciomei, Marina
Published in Bioorganic & medicinal chemistry (01.03.2010)
Published in Bioorganic & medicinal chemistry (01.03.2010)
Get full text
Journal Article
3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 1. Lead Finding
Pevarello, Paolo, Brasca, Maria Gabriella, Amici, Raffaella, Orsini, Paolo, Traquandi, Gabriella, Corti, Luca, Piutti, Claudia, Sansonna, Pietro, Villa, Manuela, Pierce, Betsy S, Pulici, Maurizio, Giordano, Patrizia, Martina, Katia, Fritzen, Edward L, Nugent, Richard A, Casale, Elena, Cameron, Alexander, Ciomei, Marina, Roletto, Fulvia, Isacchi, Antonella, Fogliatto, GianPaolo, Pesenti, Enrico, Pastori, Wilma, Marsiglio, Aurelio, Leach, Karen L, Clare, Paula M, Fiorentini, Francesco, Varasi, Mario, Vulpetti, Anna, Warpehoski, Martha A
Published in Journal of medicinal chemistry (17.06.2004)
Published in Journal of medicinal chemistry (17.06.2004)
Get full text
Journal Article
QM assisted ML for 19F NMR chemical shift prediction
Penner, Patrick, Vulpetti, Anna
Published in Journal of computer-aided molecular design (01.12.2024)
Published in Journal of computer-aided molecular design (01.12.2024)
Get full text
Journal Article
3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization
Pevarello, Paolo, Brasca, Maria Gabriella, Orsini, Paolo, Traquandi, Gabriella, Longo, Antonio, Nesi, Marcella, Orzi, Fabrizio, Piutti, Claudia, Sansonna, Pietro, Varasi, Mario, Cameron, Alexander, Vulpetti, Anna, Roletto, Fulvia, Alzani, Rachele, Ciomei, Marina, Albanese, Clara, Pastori, Wilma, Marsiglio, Aurelio, Pesenti, Enrico, Fiorentini, Francesco, Bischoff, Jim R, Mercurio, Ciro
Published in Journal of medicinal chemistry (21.04.2005)
Published in Journal of medicinal chemistry (21.04.2005)
Get full text
Journal Article