Clinical-genomic determinants of immune checkpoint blockade response in head and neck squamous cell carcinoma
Valero, Cristina, Golkaram, Mahdi, Vos, Joris L, Xu, Bin, Fitzgerald, Conall, Lee, Mark, Kaplan, Shannon, Han, Catherine Y, Pei, Xin, Sarkar, Reith, Boe, Lillian A, Pandey, Abhinav, Koh, Elizabeth S, Zuur, Charlotte L, Solit, David B, Pawlowski, Traci, Liu, Li, Ho, Alan L, Chowell, Diego, Riaz, Nadeem, Chan, Timothy A, Morris, Luc Gt
Published in The Journal of clinical investigation (01.10.2023)
Published in The Journal of clinical investigation (01.10.2023)
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Spatial relationships in the urothelial and head and neck tumor microenvironment predict response to combination immune checkpoint inhibitors
Gil-Jimenez, Alberto, van Dijk, Nick, Vos, Joris L., Lubeck, Yoni, van Montfoort, Maurits L., Peters, Dennis, Hooijberg, Erik, Broeks, Annegien, Zuur, Charlotte L., van Rhijn, Bas W. G., Vis, Daniel J., van der Heijden, Michiel S., Wessels, Lodewyk F. A.
Published in Nature communications (21.03.2024)
Published in Nature communications (21.03.2024)
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Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma
Vos, Joris L., Elbers, Joris B. W., Krijgsman, Oscar, Traets, Joleen J. H., Qiao, Xiaohang, van der Leun, Anne M., Lubeck, Yoni, Seignette, Iris M., Smit, Laura A., Willems, Stefan M., van den Brekel, Michiel W. M., Dirven, Richard, Baris Karakullukcu, M., Karssemakers, Luc, Klop, W. Martin C., Lohuis, Peter J. F. M., Schreuder, Willem H., Smeele, Ludi E., van der Velden, Lilly-Ann, Bing Tan, I., Onderwater, Suzanne, Jasperse, Bas, Vogel, Wouter V., Al-Mamgani, Abrahim, Keijser, Astrid, van der Noort, Vincent, Broeks, Annegien, Hooijberg, Erik, Peeper, Daniel S., Schumacher, Ton N., Blank, Christian U., de Boer, Jan Paul, Haanen, John B. A. G., Zuur, Charlotte L.
Published in Nature communications (22.12.2021)
Published in Nature communications (22.12.2021)
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Patterns of immune equilibrium and escape in indolent and progressing tumors
Pandey, Abhinav, Linxweiler, Maximilian, Kuo, Fengshen, Marti, Jennifer L., Roman, Benjamin, Ehdaie, Behfar, Vos, Joris L., Morris, Luc G.T.
Published in Cancer cell (14.08.2023)
Published in Cancer cell (14.08.2023)
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A pan-cancer analysis of the microbiome in metastatic cancer
Battaglia, Thomas W., Mimpen, Iris L., Traets, Joleen J.H., van Hoeck, Arne, Zeverijn, Laurien J., Geurts, Birgit S., de Wit, Gijs F., Noë, Michaël, Hofland, Ingrid, Vos, Joris L., Cornelissen, Sten, Alkemade, Maartje, Broeks, Annegien, Zuur, Charlotte L., Cuppen, Edwin, Wessels, Lodewyk, van de Haar, Joris, Voest, Emile
Published in Cell (25.04.2024)
Published in Cell (25.04.2024)
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Phase 2 trial of regorafenib in recurrent or metastatic adenoid cystic carcinoma
Desilets, Antoine, Vos, Joris L, Katabi, Nora, Kuo, Fengshen, Nadeem, Zaineb, Linxweiler, Maximilian, Ostrovnaya, Irina, Baxi, Shrujal, Dunn, Lara A, Sherman, Eric J, Pfister, David G, Morris, Luc G T, Ho, Alan L
Published in Clinical cancer research (01.10.2024)
Published in Clinical cancer research (01.10.2024)
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[18F]FDG-PET accurately identifies pathological response early upon neoadjuvant immune checkpoint blockade in head and neck squamous cell carcinoma
Vos, Joris L., Zuur, Charlotte L., Smit, Laura A., de Boer, Jan Paul, Al-Mamgani, Abrahim, van den Brekel, Michiel W. M., Haanen, John B. A. G., Vogel, Wouter V.
Published in European journal of nuclear medicine and molecular imaging (01.05.2022)
Published in European journal of nuclear medicine and molecular imaging (01.05.2022)
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Nivolumab plus ipilimumab in advanced salivary gland cancer: a phase 2 trial
Vos, Joris L., Burman, Bharat, Jain, Swati, Fitzgerald, Conall W. R., Sherman, Eric J., Dunn, Lara A., Fetten, James V., Michel, Loren S., Kriplani, Anuja, Ng, Kenneth K., Eng, Juliana, Tchekmedyian, Vatche, Haque, Sofia, Katabi, Nora, Kuo, Fengshen, Han, Catherine Y., Nadeem, Zaineb, Yang, Wei, Makarov, Vladimir, Srivastava, Raghvendra M., Ostrovnaya, Irina, Prasad, Manu, Zuur, Charlotte L., Riaz, Nadeem, Pfister, David G., Klebanoff, Christopher A., Chan, Timothy A., Ho, Alan L., Morris, Luc G. T.
Published in Nature medicine (01.12.2023)
Published in Nature medicine (01.12.2023)
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Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment
van der Leun, Anne M, Traets, Joleen J H, Vos, Joris L, Elbers, Joris B W, Patiwael, Sanne, Qiao, Xiaohang, Machuca-Ostos, Mercedes, Thommen, Daniela S, Haanen, John B A G, Schumacher, Ton N M, Zuur, Charlotte L
Published in Cancer discovery (05.10.2023)
Published in Cancer discovery (05.10.2023)
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CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors
Lei, Xin, de Groot, Daniël C., Welters, Marij J. P., de Wit, Tom, Schrama, Ellen, van Eenennaam, Hans, Santegoets, Saskia J., Oosenbrug, Timo, van der Veen, Annemarthe, Vos, Joris L., Zuur, Charlotte L., de Miranda, Noel F. C. C., Jacobs, Heinz, van der Burg, Sjoerd H., Borst, Jannie, Xiao, Yanling
Published in Cellular & molecular immunology (01.04.2024)
Published in Cellular & molecular immunology (01.04.2024)
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Quantitative Diffusion-Weighted Imaging Analyses to Predict Response to Neoadjuvant Immunotherapy in Patients with Locally Advanced Head and Neck Carcinoma
van der Hulst, Hedda J, Vos, Joris L, Tissier, Renaud, Smit, Laura A, Martens, Roland M, Beets-Tan, Regina G H, van den Brekel, Michiel W M, Zuur, Charlotte L, Castelijns, Jonas A
Published in Cancers (17.12.2022)
Published in Cancers (17.12.2022)
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Diversity of the immune microenvironment and response to checkpoint inhibitor immunotherapy in mucosal melanoma
Vos, Joris L, Traets, Joleen Jh, Qiao, Xiaohang, Seignette, Iris M, Peters, Dennis, Wouters, Michel Wjm, Hooijberg, Erik, Broeks, Annegien, van der Wal, Jacqueline E, Karakullukcu, M Baris, Klop, W Martin C, Navran, Arash, van Beurden, Marc, Brouwer, Oscar R, Morris, Luc Gt, van Poelgeest, Mariette Ie, Kapiteijn, Ellen, Haanen, John Bag, Blank, Christian U, Zuur, Charlotte L
Published in JCI insight (08.11.2024)
Published in JCI insight (08.11.2024)
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Feasibility and toxicity of neoadjuvant nivolumab with or without ipilimumab prior to extensive (salvage) surgery in patients with advanced head and neck cancer (the IMCISION trial, NCT03003637)
Zuur, Charlotte L., Elbers, Joris B. W., Vos, Joris L., van der Leun, Anne, Qiao, Xiaohang, Karakullukcu, Baris, van den Brekel, Michiel W. M., Tan, Bing, Jasperse, Bas, Vogel, Wouter V., Smit, Laura, Willems, Stefan M., van Tinteren, Harm, Al-Mamgani, Abrahim, Nijkamp, Jasper, Schumacher, Ton N., Blank, Christian U., De Boer, J. P., Haanen, John B. A. G.
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Abstract 5786: Spatial relationships in the tumor microenvironment predict response to immune checkpoint inhibitors in urothelial and head and neck cancer
Gil-Jimenez, Alberto, van Dijk, Nick, Lubeck, Yoni, van Montfoort, Maurits L., Peters, Dennis, Hooijberg, Erik, Broeks, Annegien, Vos, Joris L., Zuur, Charlotte L., van Rhijn, Bas, Vis, Daniel J., van der Heijden, Michiel S., Wessels, Lodewyk F.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 2281: Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment
van der Leun, Anne M., Traets, Joleen J., Vos, Joris L., Elbers, Joris B., Patiwael, Sanne, Qiao, Xiaohang, Machuca-Ostos, Mercedes, Thommen, Daniela S., Haanen, John B., Schumacher, Ton N., Zuur, Charlotte L.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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