NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer
Weiss-Sadan, Tommy, Ge, Maolin, Hayashi, Makiko, Gohar, Magdy, Yao, Cong-Hui, de Groot, Adriaan, Harry, Stefan, Carlin, Alexander, Fischer, Hannah, Shi, Lei, Wei, Ting-Yu, Adelmann, Charles H., Wolf, Konstantin, Vornbäumen, Tristan, Dürr, Benedikt R., Takahashi, Mariko, Richter, Marianne, Zhang, Junbing, Yang, Tzu-Yi, Vijay, Vindhya, Fisher, David E., Hata, Aaron N., Haigis, Marcia C., Mostoslavsky, Raul, Bardeesy, Nabeel, Papagiannakopoulos, Thales, Bar-Peled, Liron
Published in Cell metabolism (07.03.2023)
Published in Cell metabolism (07.03.2023)
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Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
Zhang, Junbing, Simpson, Claire M., Berner, Jacqueline, Chong, Harrison B., Fang, Jiafeng, Ordulu, Zehra, Weiss-Sadan, Tommy, Possemato, Anthony P., Harry, Stefan, Takahashi, Mariko, Yang, Tzu-yi, Richter, Marianne, Patel, Himani, Smith, Abby E., Carlin, Alexander D., Hubertus de Groot, Adriaan F., Wolf, Konstantin, Shi, Lei, Wei, Ting-Yu, Dürr, Benedikt R., Chen, Nicholas J., Vornbäumen, Tristan, Wichmann, Nina O., Mahamdeh, Mohammed S., Pooladanda, Venkatesh, Matoba, Yusuke, Kumar, Shaan, Kim, Eugene, Bouberhan, Sara, Oliva, Esther, Rueda, Bo R., Soberman, Roy J., Bardeesy, Nabeel, Liau, Brian B., Lawrence, Michael, Stokes, Matt P., Beausoleil, Sean A., Bar-Peled, Liron
Published in Cell (25.05.2023)
Published in Cell (25.05.2023)
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Journal Article
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer
Weiss-Sadan, Tommy, Ge, Maolin, Hayashi, Makiko, Gohar, Magdy, Yao, Cong-Hui, de Groot, Adriaan, Harry, Stefan, Carlin, Alexander, Fischer, Hannah, Shi, Lei, Wei, Ting-Yu, Adelmann, Charles H., Wolf, Konstantin, Vornbäumen, Tristan, Dürr, Benedikt R., Takahashi, Mariko, Richter, Marianne, Zhang, Junbing, Yang, Tzu-Yi, Vijay, Vindhya, Fisher, David E., Hata, Aaron N., Haigis, Marcia C., Mostoslavsky, Raul, Bardeesy, Nabeel, Papagiannakopoulos, Thales, Bar-Peled, Liron
Published in Cell metabolism (04.04.2023)
Published in Cell metabolism (04.04.2023)
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A histone deacetylase 3 and mitochondrial complex I axis regulates toxic formaldehyde production
Wit, Niek, Gogola, Ewa, West, James A, Vornbäumen, Tristan, Seear, Rachel V, Bailey, Peter S J, Burgos-Barragan, Guillermo, Wang, Meng, Krawczyk, Patrycja, Huberts, Daphne H E W, Gergely, Fanni, Matheson, Nicholas J, Kaser, Arthur, Nathan, James A, Patel, Ketan J
Published in Science advances (19.05.2023)
Published in Science advances (19.05.2023)
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Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway
Zhang, Junbing, Simpson, Claire M, Berner, Jacqueline, Chong, Harrison B, Fang, Jiafeng, Sahin, Zehra Ordulu, Weiss-Sadan, Tom, Possemato, Anthony P, Harry, Stefan, Takahashi, Mariko, Yang, Tzu-Yi, Richter, Marianne, Patel, Himani, Smith, Abby E, Carlin, Alexander D, Hubertus de Groot, Adriaan F, Wolf, Konstantin, Shi, Lei, Wei, Ting-Yu, Dürr, Benedikt R, Chen, Nicholas J, Vornbäumen, Tristan, Wichmann, Nina O, Pooladanda, Venkatesh, Matoba, Yuske, Kumar, Shaan, Kim, Eugene, Bouberhan, Sara, Olivia, Esther, Rueda, Bo, Bardeesy, Nabeel, Liau, Brian, Lawrence, Michael, Stokes, Matt P, Beausoleil, Sean A, Bar-Peled, Liron
Published in bioRxiv : the preprint server for biology (11.03.2023)
Published in bioRxiv : the preprint server for biology (11.03.2023)
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