Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation
Bulusu, Vinay, Tumanov, Sergey, Michalopoulou, Evdokia, van den Broek, Niels J., MacKay, Gillian, Nixon, Colin, Dhayade, Sandeep, Schug, Zachary T., Vande Voorde, Johan, Blyth, Karen, Gottlieb, Eyal, Vazquez, Alexei, Kamphorst, Jurre J.
Published in Cell reports (Cambridge) (17.01.2017)
Published in Cell reports (Cambridge) (17.01.2017)
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Journal Article
Nucleoside-catabolizing Enzymes in Mycoplasma-infected Tumor Cell Cultures Compromise the Cytostatic Activity of the Anticancer Drug Gemcitabine
Vande Voorde, Johan, Sabuncuoğlu, Suna, Noppen, Sam, Hofer, Anders, Ranjbarian, Farahnaz, Fieuws, Steffen, Balzarini, Jan, Liekens, Sandra
Published in The Journal of biological chemistry (09.05.2014)
Published in The Journal of biological chemistry (09.05.2014)
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Journal Article
Increased formate overflow is a hallmark of oxidative cancer
Meiser, Johannes, Schuster, Anne, Pietzke, Matthias, Vande Voorde, Johan, Athineos, Dimitris, Oizel, Kristell, Burgos-Barragan, Guillermo, Wit, Niek, Dhayade, Sandeep, Morton, Jennifer P, Dornier, Emmanuel, Sumpton, David, Mackay, Gillian M, Blyth, Karen, Patel, Ketan J, Niclou, Simone P, Vazquez, Alexei
Published in Nature communications (10.04.2018)
Published in Nature communications (10.04.2018)
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Journal Article
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer
Casciano, Jessica C, Perry, Caroline, Cohen-Nowak, Adam J, Miller, Katelyn D, Vande Voorde, Johan, Zhang, Qifeng, Chalmers, Susan, Sandison, Mairi E, Liu, Qin, Hedley, Ann, McBryan, Tony, Tang, Hsin-Yao, Gorman, Nicole, Beer, Thomas, Speicher, David W, Adams, Peter D, Liu, Xuefeng, Schlegel, Richard, McCarron, John G, Wakelam, Michael J O, Gottlieb, Eyal, Kossenkov, Andrew V, Schug, Zachary T
Published in British journal of cancer (17.03.2020)
Published in British journal of cancer (17.03.2020)
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Journal Article
The metabolic fate of acetate in cancer
Schug, Zachary T, Vande Voorde, Johan, Gottlieb, Eyal
Published in Nature reviews. Cancer (01.11.2016)
Published in Nature reviews. Cancer (01.11.2016)
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Journal Article
Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics
Balzarini, Jan, Das, Kalyan, Bernatchez, Jean A., Martinez, Sergio E., Ngure, Marianne, Keane, Sarah, Ford, Alan, Maguire, Nuala, Mullins, Niki, John, Jubi, Kim, Youngju, Dehaen, Wim, Voorde, Johan Vande, Liekens, Sandra, Naesens, Lieve, Götte, Matthias, Maguire, Anita R., Arnold, Eddy
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
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Journal Article
Synthesis and biological evaluation of unsaturated keto and exomethylene d-arabinopyranonucleoside analogs: Novel 5-fluorouracil analogs that target thymidylate synthase
Tzioumaki, Niki, Manta, Stella, Tsoukala, Evangelia, Voorde, Johan Vande, Liekens, Sandra, Komiotis, Dimitri, Balzarini, Jan
Published in European journal of medicinal chemistry (01.04.2011)
Published in European journal of medicinal chemistry (01.04.2011)
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Journal Article
Mycoplasma hyorhinis-encoded cytidine deaminase efficiently inactivates cytosine-based anticancer drugs
Vande Voorde, Johan, Vervaeke, Peter, Liekens, Sandra, Balzarini, Jan
Published in FEBS open bio (01.01.2015)
Published in FEBS open bio (01.01.2015)
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Journal Article
Improving the metabolic fidelity of cancer models with a physiological cell culture medium
Vande Voorde, Johan, Ackermann, Tobias, Pfetzer, Nadja, Sumpton, David, Mackay, Gillian, Kalna, Gabriela, Nixon, Colin, Blyth, Karen, Gottlieb, Eyal, Tardito, Saverio
Published in Science advances (01.01.2019)
Published in Science advances (01.01.2019)
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Journal Article
Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression
Patel, Rachana, Ford, Catriona A, Rodgers, Lisa, Rushworth, Linda K, Fleming, Janis, Mui, Ernest, Zhang, Tong, Watson, David, Lynch, Victoria, Mackay, Gillian, Sumpton, David, Sansom, Owen J, Vande Voorde, Johan, Leung, Hing Y
Published in Cancer research (Chicago, Ill.) (18.07.2022)
Published in Cancer research (Chicago, Ill.) (18.07.2022)
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Journal Article
Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells
Rattigan, Kevin M, Zarou, Martha M, Brabcova, Zuzana, Prasad, Bodhayan, Zerbst, Désirée, Sarnello, Daniele, Kalkman, Eric R, Ianniciello, Angela, Scott, Mary T, Dunn, Karen, Shokry, Engy, Sumpton, David, Copland, Mhairi, Tardito, Saverio, Vande Voorde, Johan, Mussai, Francis, Cheng, Paul, Helgason, G Vignir
Published in EMBO reports (09.10.2023)
Published in EMBO reports (09.10.2023)
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Journal Article
The pathogenesis of mesothelioma is driven by a dysregulated translatome
Grosso, Stefano, Marini, Alberto, Gyuraszova, Katarina, Voorde, Johan Vande, Sfakianos, Aristeidis, Garland, Gavin D, Tenor, Angela Rubio, Mordue, Ryan, Chernova, Tanya, Morone, Nobu, Sereno, Marco, Smith, Claire P, Officer, Leah, Farahmand, Pooyeh, Rooney, Claire, Sumpton, David, Das, Madhumita, Teodósio, Ana, Ficken, Catherine, Martin, Maria Guerra, Spriggs, Ruth V, Sun, Xiao-Ming, Bushell, Martin, Sansom, Owen J, Murphy, Daniel, MacFarlane, Marion, Le Quesne, John P C, Willis, Anne E
Published in Nature communications (13.08.2021)
Published in Nature communications (13.08.2021)
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Journal Article
Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues
Vande Voorde, Johan, Gago, Federico, Vrancken, Kristof, Liekens, Sandra, Balzarini, Jan
Published in Biochemical journal (01.07.2012)
Published in Biochemical journal (01.07.2012)
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Journal Article
Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-d-ribose-1-phosphate derivative
Vande Voorde, Johan, Quintiliani, Maurizio, McGuigan, Christopher, Liekens, Sandra, Balzarini, Jan
Published in Biochemical pharmacology (15.05.2012)
Published in Biochemical pharmacology (15.05.2012)
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Journal Article
The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2′-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes
Vande Voorde, Johan, Liekens, Sandra, McGuigan, Christopher, Murziani, Paola G.S., Slusarczyk, Magdalena, Balzarini, Jan
Published in Biochemical pharmacology (01.09.2011)
Published in Biochemical pharmacology (01.09.2011)
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Journal Article
Evidence for the Presence of Legionella Bacteriophages in Environmental Water Samples
Lammertyn, Elke, Vande Voorde, Johan, Meyen, Eef, Maes, Liesbeth, Mast, Jan, Anné, Jozef
Published in Microbial ecology (01.07.2008)
Published in Microbial ecology (01.07.2008)
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Journal Article