Soluble B-cell maturation antigen in lacrimal fluid as a potential biomarker and mediator of keratopathy in multiple myeloma
Munawar, Umair, Theuersbacher, Johanna, Steinhardt, Maximilian J, Zhou, Xiang, Han, Seungbin, Nerreter, Silvia, Vogt, Cornelia, Kurian, Shilpa, Keller, Thorsten, Regensburger, Ann-Katrin, Teufel, Eva, Mersi, Julia, Bittrich, Max, Seifert, Franziska, Haider, Malik S, Rasche, Leo, Hillenkamp, Jost, Einsele, Hermann, Kampik, Daniel, Kortüm, K Martin, Waldschmidt, Johannes M
Published in Haematologica (Roma) (04.04.2024)
Published in Haematologica (Roma) (04.04.2024)
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High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex
Zhou, Xiang, Besse, Andrej, Peter, Jessica, Steinhardt, Maximilian Johannes, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Stanojkovska, Emilia, Xiao, Xianghui, Hornburger, Hannah, Haertle, Larissa, Lopez, Max Mendez, Munawar, Umair, Riedel, Angela, Han, Seungbin, Maurits, Elmer, Overkleeft, Herman S, Florea, Bogdan, Einsele, Hermann, Kortüm, K Martin, Driessen, Christoph, Besse, Lenka, Rasche, Leo
Published in Haematologica (Roma) (01.06.2023)
Published in Haematologica (Roma) (01.06.2023)
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Clonal competition assays identify fitness signatures in cancer progression and resistance in multiple myeloma
Haertle, Larissa, Munawar, Umair, Hernández, Hipólito N. C., Arroyo‐Barea, Andres, Heckel, Tobias, Cuenca, Isabel, Martin, Lucia, Höschle, Carlotta, Müller, Nicole, Vogt, Cornelia, Bischler, Thorsten, Campo, Paula L., Han, Seungbin, Buenache, Natalia, Zhou, Xiang, Bassermann, Florian, Waldschmidt, Johannes, Steinbrunn, Torsten, Rasche, Leo, Stühmer, Thorsten, Martinez‐Lopez, Joaquin, Martin Kortüm, K., Barrio, Santiago
Published in HemaSphere (01.07.2024)
Published in HemaSphere (01.07.2024)
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P890: COMBINING SKY92 GENE EXPRESSION PROFILING WITH CYTOGENETICS ACCORDING TO R2‐ISS FOR MULTIPLE MYELOMA RISK CLASSIFICATION: THE FIRST PROSPECTIVE EVIDENCE
Zhou, Xiang, Engel, Benedict, Hofmann, Annika, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Stanojkovska, Emilia, Truger, Marietta, Weis, Philipp, Xiao, Xianghui, Eisele, Florian, Riedhammer, Christine, Johannes Steinhardt, Maximilian, Munawar, Umair, Han, Seungbin, Haertle, Larissa, Haferlach, Claudia, Einsele, Hermann, Martin Kortum, K, Rasche, Leo
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
Impaired FADD/BID signaling mediates cross-resistance to immunotherapy in Multiple Myeloma
Munawar, Umair, Zhou, Xiang, Prommersberger, Sabrina, Nerreter, Silvia, Vogt, Cornelia, Steinhardt, Maximilian J., Truger, Marietta, Mersi, Julia, Teufel, Eva, Han, Seungbin, Haertle, Larissa, Banholzer, Nicole, Eiring, Patrick, Danhof, Sophia, Navarro-Aguadero, Miguel Angel, Fernandez-Martin, Adrian, Ortiz-Ruiz, Alejandra, Barrio, Santiago, Gallardo, Miguel, Valeri, Antonio, Castellano, Eva, Raab, Peter, Rudert, Maximilian, Haferlach, Claudia, Sauer, Markus, Hudecek, Michael, Martinez-Lopez, J., Waldschmidt, Johannes, Einsele, Hermann, Rasche, Leo, Kortüm, K. Martin
Published in Communications biology (21.12.2023)
Published in Communications biology (21.12.2023)
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Bortezomib induced peripheral neuropathy and single nucleotide polymorphisms in PKNOX1
Zhou, Xiang, Han, Seungbin, Cebulla, Nadine, Haertle, Larissa, Steinhardt, Maximilian J, Schirmer, Daniel, Runau, Eva, Flamm, Leon, Terhorst, Calvin, Jähnel, Laura, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Stanojkovska, Emilia, Mersi, Julia, Munawar, Umair, Schindehütte, Magnus, Blum, Robert, Reinhold, Ann-Kristin, Scherf-Clavel, Oliver, Rittner, Heike L, Pham, Mirko, Rasche, Leo, Einsele, Hermann, Sommer, Claudia, Kortüm, K Martin
Published in Biomarker research (16.05.2023)
Published in Biomarker research (16.05.2023)
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Successful inhibition of excitotoxic neuronal damage and microglial activation after delayed application of interleukin-1 receptor antagonist
Vogt, Cornelia, Hailer, Nils P., Ghadban, Chalid, Korf, Horst-Werner, Dehghani, Faramarz
Published in Journal of neuroscience research (15.11.2008)
Published in Journal of neuroscience research (15.11.2008)
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Secondary Genetic Events Impact the Expression of Key Immunotargets on the Surface of Multiple Myeloma Cells
Munawar, Umair, Eiring, Patrick, Vogt, Cornelia, Haertle, Larissa, Han, Seungbin, Nerreter, Silvia, Teufel, Eva, Steinhardt, Max, Zhou, Xiang, Barrio, Santiago, Einsele, Hermann, Waldschmidt, Johannes M, Rasche, Leo, Sauer, Markus, Kortüm, K. Martin
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma
Han, Seungbin, Munawar, Umair, Haertle, Larissa, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Zhou, Xiang, Steinhardt, Max, Eisele, Florian, Raab, Peter, Truger, Marietta, Dorado, Sara, Barrio, Santiago, Haferlach, Claudia, Martínez-López, Joaquin, Einsele, Hermann, Rasche, Leo, Waldschmidt, Johannes M, Kortüm, K. Martin
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Bone Marrow Plasma Cell Infiltration Is a Prognostic Factor for Response to AL Amyloidosis Therapy
Steinhardt, Maximilian J, Cejka, Vladimir, Morbach, Caroline, Papagianni, Aikaterini, Nerreter, Silvia, Vogt, Cornelia, Munawar, Umair, Han, Seungbin, Rasche, Leo, Waldschmidt, Johannes M, Sommer, Claudia, Störk, Stefan, Einsele, Hermann, Kortüm, K. Martin
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients
Steinhardt, Maximilian J, Eiring, Patrick, Vogt, Cornelia, Munawar, Umair, Han, Seungbin, Haertle, Larissa, Nerreter, Silvia, Teufel, Eva, Mersi, Julia, Zhou, Xiang, Hudecek, Michael, Martinez-Lopez, Joaquin, Waldschmidt, Johannes M, Einsele, Hermann, Rasche, Leo, Sauer, Markus, Kortüm, K. Martin
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Cereblon enhancer methylation and IMiD resistance in multiple myeloma
Haertle, Larissa, Barrio, Santiago, Munawar, Umair, Han, Seungbin, Zhou, Xiang, Vogt, Cornelia, Fernández, Rafael Alonso, Bittrich, Max, Ruiz-Heredia, Yanira, Da Viá, Matteo, Zovko, Josip, Garitano-Trojaola, Andoni, Bolli, Niccolò, Ruckdeschel, Anna, Stühmer, Thorsten, Chatterjee, Manik, Kull, Miriam, Krönke, Jan, Agirre, Xabier, Martin-Subero, Jose I., Raab, Peter, Einsele, Hermann, Rasche, Leo, Martinez-Lopez, Joaquin, Haaf, Thomas, Kortüm, K. Martin
Published in Blood (04.11.2021)
Published in Blood (04.11.2021)
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CIC Mutation as a Molecular Mechanism of Acquired Resistance to Combined BRAF-MEK Inhibition in Extramedullary Multiple Myeloma with Central Nervous System Involvement
Da Vià, Matteo Claudio, Solimando, Antonio Giovanni, Garitano-Trojaola, Andoni, Barrio, Santiago, Munawar, Umair, Strifler, Susanne, Haertle, Larissa, Rhodes, Nadine, Teufel, Eva, Vogt, Cornelia, Lapa, Constantin, Beilhack, Andreas, Rasche, Leo, Einsele, Hermann, Kortüm, K Martin
Published in The oncologist (Dayton, Ohio) (01.02.2020)
Published in The oncologist (Dayton, Ohio) (01.02.2020)
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Journal Article
CIC Mutation as a Molecular Mechanism of Acquired Resistance to Combined BRAF‐MEK Inhibition in Extramedullary Multiple Myeloma with Central Nervous System Involvement
Da Vià, Matteo Claudio, Solimando, Antonio Giovanni, Garitano‐Trojaola, Andoni, Barrio, Santiago, Munawar, Umair, Strifler, Susanne, Haertle, Larissa, Rhodes, Nadine, Teufel, Eva, Vogt, Cornelia, Lapa, Constantin, Beilhack, Andreas, Rasche, Leo, Einsele, Hermann, Kortüm, K. Martin
Published in The oncologist (Dayton, Ohio) (01.02.2020)
Published in The oncologist (Dayton, Ohio) (01.02.2020)
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The T-Cell Metabolic Phenotype Is Dependent on Risk Status and Degree of PC Bone Marrow Infiltration in Multiple Myeloma
John, Mara, Helal, Moutaz, Grundheber, Lars, Mattavelli, Greta, Afrin, Nazia, Zhou, Xiang, Engel, Benedict, Schmitz, Werner, Stanojkovska, Emilia, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Mersi, Julia, Einsele, Hermann, Kortuem, K. Martin, Riedel, Angela, Rasche, Leo
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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De novo mutations in HCN1 cause early infantile epileptic encephalopathy
Nava, Caroline, Dalle, Carine, Rastetter, Agnès, Striano, Pasquale, de Kovel, Carolien G F, Nabbout, Rima, Cancès, Claude, Ville, Dorothée, Brilstra, Eva H, Gobbi, Giuseppe, Raffo, Emmanuel, Bouteiller, Delphine, Marie, Yannick, Trouillard, Oriane, Robbiano, Angela, Keren, Boris, Agher, Dahbia, Roze, Emmanuel, Lesage, Suzanne, Nicolas, Aude, Brice, Alexis, Baulac, Michel, Vogt, Cornelia, El Hajj, Nady, Schneider, Eberhard, Suls, Arvid, Weckhuysen, Sarah, Gormley, Padhraig, Lehesjoki, Anna-Elina, De Jonghe, Peter, Helbig, Ingo, Baulac, Stéphanie, Zara, Federico, Koeleman, Bobby P C, Haaf, Thomas, LeGuern, Eric, Depienne, Christel
Published in Nature genetics (01.06.2014)
Published in Nature genetics (01.06.2014)
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Changes in T-cell subsets, preexisting cytopenias and hyperferritinaemia correlate with cytopenias after BCMA targeted CAR T-cell therapy in relapsed/refractory multiple myeloma: Results from a prospective comprehensive biomarker study
Zhou, Xiang, Wagner, Vivien, Scheller, Lukas, Stanojkovska, Emilia, Riedhammer, Christine, Xiao, Xianghui, Steinhardt, Maximilian Johannes, Vogt, Cornelia, Nerreter, Silvia, Eisele, Florian, John, Mara, Munawar, Umair, Kadel, Sofie-Katrin, Mersi, Julia, Ruckdeschel, Anna, Schimanski, Sven, Haertle, Larissa, Waldschmidt, Johannes Moritz, Han, Seungbin, Topp, Max, Duell, Johannes, Einsele, Hermann, Riedel, Angela, Kortüm, K Martin, Rasche, Leo
Published in British journal of haematology (08.05.2024)
Published in British journal of haematology (08.05.2024)
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Journal Article
Single-Nucleotide Variants and Epimutations Induce Proteasome Inhibitor Resistance in Multiple Myeloma
Haertle, Larissa, Barrio, Santiago, Munawar, Umair, Han, Seungbin, Zhou, Xiang, Simicek, Michal, Vogt, Cornelia, Truger, Marietta, Fernandez, Rafael Alonso, Steinhardt, Maximilian, Weingart, Julia, Snaurova, Renata, Nerreter, Silvia, Teufel, Eva, Garitano-Trojaola, Andoni, Da Viá, Matteo, Ruiz-Heredia, Yanira, Rosenwald, Andreas, Bolli, Niccolò, Hajek, Roman, Raab, Peter, Raab, Marc S, Weinhold, Niels, Haferlach, Claudia, Haaf, Thomas, Martinez-Lopez, Joaquin, Einsele, Hermann, Rasche, Leo, Kortüm, K Martin
Published in Clinical cancer research (04.01.2023)
Published in Clinical cancer research (04.01.2023)
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High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to low-dose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex
Zhou, Xiang, Besse, Andrej, Peter, Jessica, Steinhardt, Maximilian Johannes, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Stanojkovska, Emilia, Xiao, Xianghui, Hornburger, Hannah, Haertle, Larissa, Mendez-Lopez, Max, Munawar, Umair, Riedel, Angela, Han, Seungbin, Maurits, Elmer, Overkleeft, Herman S., Florea, Bogdan, Einsele, Hermann, Kortüm, K. Martin, Driessen, Christoph, Besse, Lenka, Rasche, Leo
Published in Haematologica (Roma) (01.06.2023)
Published in Haematologica (Roma) (01.06.2023)
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Multiomic Analysis of CD38 Expression Levels in 209 Untreated and Daratumumab-Resistant Patients
Steinhardt, Max Johannes, Eiring, Patrick, Munawar, Umair, Haertle, Larissa, Han, Seungbin, Vogt, Cornelia, Nerreter, Silvia, Teufel, Eva, Mersi, Julia, Bittrich, Max, Danhof, Sophia, Truger, Marietta, Haaf, Thomas, Barrio, Santiago, Zhou, Xiang, Martínez-López, Joaquín, Haferlach, Claudia, Hudecek, Michael, Einsele, Hermann, Rasche, Leo, Sauer, Markus, Kortuem, K. Martin
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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