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Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

by Claringbould, Annique, Westra, Harm-Jan, Bonder, Marc Jan, Deelen, Patrick, Kirsten, Holger, Saha, Ashis, Yazar, Seyhan, Brugge, Harm, Oelen, Roy, de Vries, Dylan H., van der Wijst, Monique G. P., Kasela, Silva, Pervjakova, Natalia, Alves, Isabel, Favé, Marie-Julie, Agbessi, Mawussé, Christiansen, Mark W., Jansen, Rick, Seppälä, Ilkka, Tong, Lin, Teumer, Alexander, Schramm, Katharina, Hemani, Gibran, Verlouw, Joost, Yaghootkar, Hanieh, Sönmez Flitman, Reyhan, Brown, Andrew, Kukushkina, Viktorija, Kalnapenkis, Anette, Rüeger, Sina, Porcu, Eleonora, Kettunen, Johannes, Lee, Bernett, Zhang, Futao, Qi, Ting, Arindrarto, Wibowo, Beutner, Frank, Dmitrieva, Julia, Elansary, Mahmoud, Fairfax, Benjamin P., Georges, Michel, Heijmans, Bastiaan T., Hewitt, Alex W., Kähönen, Mika, Kim, Yungil, Knight, Julian C., Kovacs, Peter, Krohn, Knut, Li, Shuang, Loeffler, Markus, Marigorta, Urko M., Mei, Hailang, Momozawa, Yukihide, Müller-Nurasyid, Martina, Nauck, Matthias, Nivard, Michel G., Penninx, Brenda W. J. H., Pritchard, Jonathan K., Raitakari, Olli T., Rotzschke, Olaf, Slagboom, Eline P., Stehouwer, Coen D. A., Stumvoll, Michael, Sullivan, Patrick, ’t Hoen, Peter A. C., Thiery, Joachim, Tönjes, Anke, van Dongen, Jenny, van Iterson, Maarten, Veldink, Jan H., Völker, Uwe, Warmerdam, Robert, Wijmenga, Cisca, Swertz, Morris, Andiappan, Anand, Montgomery, Grant W., Ripatti, Samuli, Perola, Markus, Kutalik, Zoltan, Dermitzakis, Emmanouil, Bergmann, Sven, van Meurs, Joyce, Prokisch, Holger, Ahsan, Habibul, Pierce, Brandon L., Lehtimäki, Terho, Psaty, Bruce M., Gharib, Sina A., Awadalla, Philip, Milani, Lili, Ouwehand, Willem H., Downes, Kate, Stegle, Oliver, Battle, Alexis, Visscher, Peter M., Yang, Jian, Powell, Joseph, Gibson, Greg, Esko, Tõnu, Franke, Lude
Published in Nature genetics (01.09.2021)

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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

by Karlsson Linnér, Richard, Biroli, Pietro, Kong, Edward, Meddens, S. Fleur W., Wedow, Robbee, Fontana, Mark Alan, Lebreton, Maël, Tino, Stephen P., Abdellaoui, Abdel, Hammerschlag, Anke R., Nivard, Michel G., Okbay, Aysu, Rietveld, Cornelius A., Timshel, Pascal N., Trzaskowski, Maciej, Vlaming, Ronald de, Zünd, Christian L., Bao, Yanchun, Buzdugan, Laura, Caplin, Ann H., Chen, Chia-Yen, Eibich, Peter, Fontanillas, Pierre, Gonzalez, Juan R., Joshi, Peter K., Karhunen, Ville, Kleinman, Aaron, Levin, Remy Z., Lill, Christina M., Meddens, Gerardus A., Muntané, Gerard, Sanchez-Roige, Sandra, Rooij, Frank J. van, Taskesen, Erdogan, Wu, Yang, Zhang, Futao, Auton, Adam, Boardman, Jason D., Clark, David W., Conlin, Andrew, Dolan, Conor C., Fischbacher, Urs, Groenen, Patrick J. F., Harris, Kathleen Mullan, Hasler, Gregor, Hofman, Albert, Ikram, Mohammad A., Jain, Sonia, Karlsson, Robert, Kessler, Ronald C., Kooyman, Maarten, MacKillop, James, Männikkö, Minna, Morcillo-Suarez, Carlos, McQueen, Matthew B., Schmidt, Klaus M., Smart, Melissa C., Sutter, Matthias, Thurik, A. Roy, Uitterlinden, André G., White, Jon, Wit, Harriet de, Yang, Jian, Bertram, Lars, Boomsma, Dorret I., Esko, Tõnu, Fehr, Ernst, Hinds, David A., Johannesson, Magnus, Kumari, Meena, Laibson, David, Magnusson, Patrik K. E., Meyer, Michelle N., Navarro, Arcadi, Palmer, Abraham A., Pers, Tune H., Posthuma, Danielle, Schunk, Daniel, Stein, Murray B., Svento, Rauli, Tiemeier, Henning, Timmers, Paul R. H. J., Turley, Patrick, Ursano, Robert J., Wagner, Gert G., Wilson, James F., Gratten, Jacob, Lee, James J., Cesarini, David, Benjamin, Daniel J., Koellinger, Philipp D., Beauchamp, Jonathan P.
Published in Nature genetics (01.02.2019)

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Genetic studies of body mass index yield new insights for obesity biology

by Croteau-Chonka, Damien C., Wood, Andrew R., Absher, Devin, Bragg-Gresham, Jennifer L., Buyske, Steven, Feitosa, Mary F., Mangino, Massimo, Mateo Leach, Irene, Palmer, Cameron D., Pasko, Dorota, Ju Sung, Yun, Teumer, Alexander, van der Laan, Sander W., Ärnlöv, Johan, Berne, Christian, Bonnycastle, Lori L., Bruinenberg, Marcel, Ida Chen, Yii-Der, de Craen, Anton J. M., Delgado, Graciela, Fraser, Ross M., Grönberg, Henrik, Gusto, Gaëlle, Hassinen, Maija, Jeff, Janina M., Kinnunen, Leena, Kratzer, Wolfgang, Lee, Nanette R., Lichtner, Peter, Lind, Lars, Sin Lo, Ken, Lorbeer, Roberto, Mahajan, Anubha, Milani, Lili, Monda, Keri L., Nolte, Ilja M., Pilz, Stefan, Rettig, Rainer, Ripke, Stephan, Sanna, Serena, Schumacher, Fredrick R., Scott, William R., Smolonska, Joanna, Stirrups, Kathleen, Stringham, Heather M., Uh, Hae-Won, Vandenput, Liesbeth, Warren, Helen R., Brennan, Eoin P., Drong, Alexander W., Min, Josine L., Okada, Yukinori, Takahashi, Atsushi, Tanaka, Toshihiro, Westra, Harm-Jan, Campbell, Harry, den Ruijter, Hester M., Erbel, Raimund, Farrall, Martin, Franco, Oscar H., Gejman, Pablo V., Gieger, Christian, Gottesman, Omri, Hingorani, Aroon D., Hyppönen, Elina, Jarvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Johansen, Berit, Kooperberg, Charles, Langenberg, Claudia, Postma, Dirkje S., Price, Jackie F., Rao, D. C., Rioux, John D., Schunkert, Heribert, Shuldiner, Alan R., Strauch, Konstantin, Tremblay, Angelo, Adair, Linda S., de Bakker, Paul I. W., Ferrucci, Luigi, Hveem, Kristian, März, Winfried, Munroe, Patricia B., Njølstad, Inger, Palmer, Colin N. A., Pedersen, Nancy L., Pérusse, Louis, Saaristo, Timo E., Saleheen, Danish, Sattar, Naveed, Eline Slagboom, P., Tuomilehto, Jaakko, Deloukas, Panos, Stefansson, Kari, van Duijn, Cornelia M., Willer, Cristen J., Ingelsson, Erik, Hirschhorn, Joel N., Loos, Ruth J. F.
Published in Nature (London) (12.02.2015)

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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

by Li, Yong, Wuttke, Matthias, Kirsten, Holger, Qiu, Chengxiang, Gorski, Mathias, Giri, Ayush, Li, Man, Noce, Damia, van der Most, Peter J., Horn, Katrin, Xu, Yizhe, Fuchsberger, Christian, Baptista, Daniela, Brumat, Marco, Campana, Eric, Campbell, Archie, Campbell, Harry, Carroll, Robert J., Catamo, Eulalia, Ciullo, Marina, Concas, Maria Pina, Coresh, Josef, De Grandi, Alessandro, Dittrich, Katalin, Eckardt, Kai-Uwe, Endlich, Karlhans, Evans, Michele K., Gieger, Christian, Gudbjartsson, Daniel F., Hicks, Andrew A., Hofer, Edith, Huang, Wei, Hutri-Kähönen, Nina, Hwang, Shih-Jen, Ikram, M. Arfan, Jakobsdottir, Johanna, Jonsson, Helgi, Joshi, Peter K., Josyula, Navya Shilpa, Jung, Bettina, Kähönen, Mika, Kamatani, Yoichiro, Kanai, Masahiro, Kooner, Jaspal S., Körner, Antje, Kovacs, Peter, Krämer, Bernhard K., Kronenberg, Florian, Kubo, Michiaki, Kühnel, Brigitte, Lange, Leslie A., Loeffler, Markus, Loos, Ruth J. F., Lyytikäinen, Leo-Pekka, Matsuda, Koichi, Meitinger, Thomas, Mishra, Pashupati P., Montgomery, Grant W., Müller-Nurasyid, Martina, Nadkarni, Girish N., Nolte, Ilja M., Noordam, Raymond, Perls, Thomas, Pirastu, Mario, Pistis, Giorgio, Ponte, Belen, Poulain, Tanja, Rabelink, Ton J., Rettig, Rainer, Rheinberger, Myriam, Rice, Kenneth M., Rudan, Igor, Rueedi, Rico, Ryan, Kathleen A., Saba, Yasaman, Shaffer, Christian M., Smith, Albert V., Stumvoll, Michael, Thiery, Joachim, Thio, Chris H. L., Thorsteinsdottir, Unnur, Uitterlinden, André G., Völker, Uwe, Waldenberger, Melanie, Whitfield, John B., Wilson, James F., Zonderman, Alan B., Wilson, James G., Ho, Kevin, Parsa, Afshin, Psaty, Bruce M., Böger, Carsten A., Butterworth, Adam S., Stefansson, Kari, Heid, Iris M., Hung, Adriana M., Teumer, Alexander, Pattaro, Cristian, Woodward, Owen M., Vitart, Veronique
Published in Nature genetics (01.10.2019)

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New genetic loci link adipose and insulin biology to body fat distribution

by Ferreira, Teresa, Locke, Adam E., Justice, Anne E., Wu, Joseph M. W., Buchkovich, Martin L., Heard-Costa, Nancy L., Drong, Alexander W., Gustafsson, Stefan, Fall, Tove, Scherag, André, Absher, Devin, Ehret, Georg B., Kleber, Marcus E., Peters, Marjolein J., Albrecht, Eva, Bellis, Claire, Böhringer, Stefan, Böttcher, Yvonne, Clarke, Robert, Eklund, Niina, Erdos, Michael R., Estrada, Karol, Eury, Elodie, Friedrich, Nele, Giedraitis, Vilmantas, Gigante, Bruna, Go, Alan S., Hallmans, Goran, Hassinen, Maija, Hunt, Steven C., Koenig, Wolfgang, Kratzer, Wolfgang, Lindström, Jaana, Merger, Sigrun, Mihailov, Evelin, Mills, Rebecca, Moayyeri, Alireza, Müller-Nurasyid, Martina, Nalls, Michael A., Narisu, Narisu, Nolte, Ilja M., Sanna, Serena, Seufferlein, Thomas, Wennauer, Roman, Choi, Murim, Karpe, Fredrik, Keildson, Sarah, Kiryluk, Krzysztof, Lifton, Richard P., Ma, Baoshan, Nicholson, George, Schadt, Eric E., Scott, Robert A., Westra, Harm-Jan, Beilby, John, Bergman, Richard N., Brown, Morris J., Campbell, Harry, Danesh, John, de Geus, Eco J. C., Ferrannini, Ele, Ferrières, Jean, Haiman, Christopher A., Johansen, Berit, Jousilahti, Pekka, Keinanen-Kiukaanniemi, Sirkka M., Kooperberg, Charles, Kumari, Meena, Matise, Tara C., Möhlenkamp, Stefan, Nelis, Mari, Ong, Ken K., Palmer, Lyle J., Ritchie, Marylyn D., Salomaa, Veikko, Samani, Nilesh J., Saramies, Jouko, Sarzynski, Mark A., Schwarz, Peter E. H., Strauch, Konstantin, Boehm, Bernhard O., Chambers, John C., Grabe, Hans-Jörgen, Hamsten, Anders, Kivimaki, Mika, März, Winfried, Pedersen, Nancy L., Pérusse, Louis, Power, Chris, Rauramaa, Rainer, Rivadeneira, Fernando, Thorsteinsdottir, Unnur, Stumvoll, Michael, Watkins, Hugh, Wichmann, H-Erich, Hunter, David J., Qi, Lu, Speliotes, Elizabeth K., Fox, Caroline S., Barroso, Inês
Published in Nature (London) (12.02.2015)

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