S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma
Wang, Yanmeng, Muylaert, Catharina, Wyns, Arne, Vlummens, Philip, De Veirman, Kim, Vanderkerken, Karin, Zaal, Esther, Berkers, Celia, Moreaux, Jérome, De Bruyne, Elke, Menu, Eline
Published in Haematologica (Roma) (01.01.2024)
Published in Haematologica (Roma) (01.01.2024)
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Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis
Oudaert, Inge, Satilmis, Hatice, Vlummens, Philip, De Brouwer, Wouter, Maes, Anke, Hose, Dirk, De Bruyne, Elke, Ghesquière, Bart, Vanderkerken, Karin, De Veirman, Kim, Menu, Eline
Published in Journal of experimental & clinical cancer research (01.02.2022)
Published in Journal of experimental & clinical cancer research (01.02.2022)
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Bortezomib-based induction followed by stem cell transplantation in light chain amyloidosis: results of the multicenter HOVON 104 trial
Minnema, Monique C, Nasserinejad, Kazem, Hazenberg, Bouke, Hegenbart, Ute, Vlummens, Philip, Ypma, Paula F, Kröger, Nicolaus, Wu, Ka Lung, Kersten, Marie Jose, Schaafsma, M Ron, Croockewit, Sandra, de Waal, Esther, Zweegman, Sonja, Tick, Lidwien, Broijl, Annemieke, Koene, Harry, Bos, Gerard, Sonneveld, Pieter, Schönland, Stefan
Published in Haematologica (Roma) (01.11.2019)
Published in Haematologica (Roma) (01.11.2019)
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The Transfer of Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma
Faict, Sylvia, Oudaert, Inge, D'Auria, Ludovic, Dehairs, Jonas, Maes, Ken, Vlummens, Philip, De Veirman, Kim, De Bruyne, Elke, Fostier, Karel, Vande Broek, Isabelle, Schots, Rik, Vanderkerken, Karin, Swinnen, Johannes V, Menu, Eline
Published in Cancers (20.11.2019)
Published in Cancers (20.11.2019)
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The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma
Maes, Anke, Maes, Ken, De Raeve, Hendrik, De Smedt, Eva, Vlummens, Philip, Szablewski, Vanessa, Devin, Julie, Faict, Sylvia, De Veirman, Kim, Menu, Eline, Offner, Fritz, Spaargaren, Marcel, Moreaux, Jérôme, Vanderkerken, Karin, Van Valckenborgh, Els, De Bruyne, Elke
Published in British journal of cancer (11.06.2019)
Published in British journal of cancer (11.06.2019)
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Musculocontractural Ehlers‐Danlos Syndrome (former EDS type VIB) and adducted thumb clubfoot syndrome (ATCS) represent a single clinical entity caused by mutations in the dermatan‐4‐sulfotransferase 1 encoding CHST14 gene
Malfait, Fransiska, Syx, Delfien, Vlummens, Philip, Symoens, Sofie, Nampoothiri, Sheela, Hermanns‐Lê, Trinh, Van Laer, Lut, De Paepe, Anne
Published in Human mutation (01.11.2010)
Published in Human mutation (01.11.2010)
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CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma
De Veirman, Kim, Puttemans, Janik, Krasniqi, Ahmet, Ertveldt, Thomas, Hanssens, Heleen, Romao, Ema, Hose, Dirk, Goyvaert, Cleo, Vlummens, Philip, Muyldermans, Serge, Breckpot, Karine, Bruchertseifer, Frank, Morgenstern, Alfred, D'Huyvetter, Matthias, Devoogdt, Nick
Published in Oncoimmunology (01.01.2021)
Published in Oncoimmunology (01.01.2021)
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Predicting cytogenetic risk in multiple myeloma using conventional whole-body MRI, spinal dynamic contrast-enhanced MRI, and spinal diffusion-weighted imaging
Van Den Berghe, Thomas, Verberckmoes, Bert, Kint, Nicolas, Wallaert, Steven, De Vos, Nicolas, Algoet, Chloé, Behaeghe, Maxim, Dutoit, Julie, Van Roy, Nadine, Vlummens, Philip, Dendooven, Amélie, Van Dorpe, Jo, Offner, Fritz, Verstraete, Koenraad
Published in Insights into imaging (10.04.2024)
Published in Insights into imaging (10.04.2024)
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A novel splice variant in the N-propeptide of COL5A1 causes an EDS phenotype with severe kyphoscoliosis and eye involvement
Symoens, Sofie, Malfait, Fransiska, Vlummens, Philip, Hermanns-Lê, Trinh, Syx, Delfien, De Paepe, Anne
Published in PloS one (17.05.2011)
Published in PloS one (17.05.2011)
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Tasquinimod suppresses tumor cell growth and bone resorption by targeting immunosuppressive myeloid cells and inhibiting c-MYC expression in multiple myeloma
Fan, Rong, Satilmis, Hatice, Vandewalle, Niels, Verheye, Emma, Vlummens, Philip, Maes, Anke, Muylaert, Catharina, De Bruyne, Elke, Menu, Eline, Evans, Holly, Chantry, Andrew, De Beule, Nathan, Hose, Dirk, Törngren, Marie, Eriksson, Helena, Vanderkerken, Karin, Maes, Ken, Breckpot, Karine, De Veirman, Kim
Published in Journal for immunotherapy of cancer (01.01.2023)
Published in Journal for immunotherapy of cancer (01.01.2023)
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Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach
Vlummens, Philip, Verhulst, Stefaan, De Veirman, Kim, Maes, Anke, Menu, Eline, Moreaux, Jérome, De Boussac, Hugues, Robert, Nicolas, De Bruyne, Elke, Hose, Dirk, Offner, Fritz, Vanderkerken, Karin, Maes, Ken
Published in Frontiers in cell and developmental biology (08.06.2022)
Published in Frontiers in cell and developmental biology (08.06.2022)
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A challenging diagnosis of a nonsecretor plasma cell dyscrasia with pleomorphic plasmablastic morphology
Van Landeghem, Stijn, Capiau, Sara, Bayart, Jean‐Louis, Vlummens, Philip, Van Dorpe, Jo, Van Roy, Nadine, Philippé, Jan
Published in Clinical case reports (01.12.2020)
Published in Clinical case reports (01.12.2020)
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Daratumumab plus pomalidomide and dexamethasone versus pomalidomide and dexamethasone alone in previously treated multiple myeloma (APOLLO): an open-label, randomised, phase 3 trial
Dimopoulos, Meletios A, Terpos, Evangelos, Boccadoro, Mario, Delimpasi, Sosana, Beksac, Meral, Katodritou, Eirini, Moreau, Philippe, Baldini, Luca, Symeonidis, Argiris, Bila, Jelena, Oriol, Albert, Mateos, Maria-Victoria, Einsele, Hermann, Orfanidis, Ioannis, Ahmadi, Tahamtan, Ukropec, Jon, Kampfenkel, Tobias, Schecter, Jordan M, Qiu, Yanping, Amin, Himal, Vermeulen, Jessica, Carson, Robin, Sonneveld, Pieter, Alegre Amor, Adrian, Baldini, Luca, Beksac, Meral, Belotti, Angelo, Benboubker, Lotfi, Besemer, Britta, Besisik, Sevgi, Bila, Jelena, Boccadoro, Mario, Cavo, Michele, De La Rubia Comos, Javier, Delimpasi, Sosana, Dimopoulos, Meletios A., Doyen, Chantal, Dytfeld, Dominik, Engelhardt, Monika, Facon, Thierry, Foà, Roberto, Goldschmidt, Hartmut, Grosicki, Sebastian, Hajek, Roman, Hayri Ozsan, Guner, Hulin, Cyrille, Iversen, Brian, Karlin, Lionel, Katodritou, Eirini, Knop, Stefan, Kyrtsonis, Marie-Christine, Lahuerta, Juan Jose, Leleu, Xavier, Martinez Chamorro, Carmen, Mateos Manteca, María-Victoria, Meuleman, Nathalie, Minnema, Monique, Moreau, Philippe, Offidani, Massino, Oriol Rocafiguera, Albert, Pehlivan, Mustafa, Pour, Ludek, Roerdink, Henk Th.J., Rosinol Dacsh, Laura, Salwender, Hans, Sonneveld, Pieter, Symeonidis, Anargyros, Toftmann Hansen, Charlotte, Tuglular, Tulin, Unal, Ali, Vlummens, Philip, Vural, Filiz, Wu, Ka Lung, Zweegman, Sonja
Published in The lancet oncology (01.06.2021)
Published in The lancet oncology (01.06.2021)
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Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis
Van der Vreken, Arne, Oudaert, Inge, Ates, Gamze, Faict, Sylvia, Vlummens, Philip, Satilmis, Hatice, Fan, Rong, Maes, Anke, Massie, Ann, De Veirman, Kim, De Bruyne, Elke, Vanderkerken, Karin, Menu, Eline
Published in The Journal of pathology (01.06.2023)
Published in The Journal of pathology (01.06.2023)
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System Xc− inhibition blocks bone marrow-multiple myeloma exosomal crosstalk, thereby countering bortezomib resistance
Wang, Fang, Oudaert, Inge, Tu, Chenggong, Maes, Anke, Van der Vreken, Arne, Vlummens, Philip, De Bruyne, Elke, De Veirman, Kim, Wang, Yanmeng, Fan, Rong, Massie, Ann, Vanderkerken, Karin, Shang, Peng, Menu, Eline
Published in Cancer letters (01.06.2022)
Published in Cancer letters (01.06.2022)
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Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells
Clarisse, Dorien, Prekovic, Stefan, Vlummens, Philip, Staessens, Eleni, Van Wesemael, Karlien, Thommis, Jonathan, Fijalkowska, Daria, Acke, Guillaume, Zwart, Wilbert, Beck, Ilse M., Offner, Fritz, De Bosscher, Karolien
Published in Cellular and molecular life sciences : CMLS (01.09.2023)
Published in Cellular and molecular life sciences : CMLS (01.09.2023)
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Subgroup analysis of ICARIA‐MM study in relapsed/refractory multiple myeloma patients with high‐risk cytogenetics
Harrison, Simon J., Perrot, Aurore, Alegre, Adrian, Simpson, David, Wang, Ming Chung, Spencer, Andrew, Delimpasi, Sosana, Hulin, Cyrille, Sunami, Kazutaka, Facon, Thierry, Vlummens, Philip, Yong, Kwee, Campana, Frank, Inchauspé, Marlène, Macé, Sandrine, Risse, Marie‐Laure, Velde, Helgi, Richardson, Paul
Published in British journal of haematology (01.07.2021)
Published in British journal of haematology (01.07.2021)
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Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway
De Veirman, Kim, Menu, Eline, Maes, Ken, De Beule, Nathan, De Smedt, Eva, Maes, Anke, Vlummens, Philip, Fostier, Karel, Kassambara, Alboukadel, Moreaux, Jérôme, Van Ginderachter, Jo A., De Bruyne, Elke, Vanderkerken, Karin, Van Valckenborgh, Els
Published in Cancer letters (01.02.2019)
Published in Cancer letters (01.02.2019)
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