Adverse effects of statin therapy: perception vs. the evidence – focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract
Mach, François, Ray, Kausik K, Wiklund, Olov, Corsini, Alberto, Catapano, Alberico L, Bruckert, Eric, De Backer, Guy, Hegele, Robert A, Hovingh, G Kees, Jacobson, Terry A, Krauss, Ronald M, Laufs, Ulrich, Leiter, Lawrence A, März, Winfried, Nordestgaard, Børge G, Raal, Frederick J, Roden, Michael, Santos, Raul D, Stein, Evan A, Stroes, Erik S, Thompson, Paul D, Tokgözoğlu, Lale, Vladutiu, Georgirene D, Gencer, Baris, Stock, Jane K, Ginsberg, Henry N, Chapman, M John
Published in European heart journal (14.07.2018)
Published in European heart journal (14.07.2018)
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GATM Polymorphism Associated with the Risk for Statin-Induced Myopathy Does Not Replicate in Case-Control Analysis of 715 Dyslipidemic Individuals
Luzum, Jasmine A., Kitzmiller, Joseph P., Isackson, Paul J., Ma, Changxing, Medina, Marisa W., Dauki, Anees M., Mikulik, Eduard B., Ochs-Balcom, Heather M., Vladutiu, Georgirene D.
Published in Cell metabolism (07.04.2015)
Published in Cell metabolism (07.04.2015)
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CPT2 gene mutations resulting in lethal neonatal or severe infantile carnitine palmitoyltransferase II deficiency
Isackson, Paul J., Bennett, Michael J., Lichter-Konecki, Uta, Willis, Mary, Nyhan, William L., Sutton, V. Reid, Tein, Ingrid, Vladutiu, Georgirene D.
Published in Molecular genetics and metabolism (01.08.2008)
Published in Molecular genetics and metabolism (01.08.2008)
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Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management
Stroes, Erik S, Thompson, Paul D, Corsini, Alberto, Vladutiu, Georgirene D, Raal, Frederick J, Ray, Kausik K, Roden, Michael, Stein, Evan, Tokgözoğlu, Lale, Nordestgaard, Børge G, Bruckert, Eric, De Backer, Guy, Krauss, Ronald M, Laufs, Ulrich, Santos, Raul D, Hegele, Robert A, Hovingh, G Kees, Leiter, Lawrence A, Mach, Francois, März, Winfried, Newman, Connie B, Wiklund, Olov, Jacobson, Terry A, Catapano, Alberico L, Chapman, M John, Ginsberg, Henry N
Published in European heart journal (01.05.2015)
Published in European heart journal (01.05.2015)
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Association of SLCO1B1 c.521T>C (rs4149056) with discontinuation of atorvastatin due to statin-associated muscle symptoms
Linskey, Derek W, English, Joseph D, Perry, Daniel A, Ochs-Balcom, Heather M, Ma, Changxing, Isackson, Paul J, Vladutiu, Georgirene D, Luzum, Jasmine A
Published in Pharmacogenetics and genomics (01.12.2020)
Published in Pharmacogenetics and genomics (01.12.2020)
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Ryanodine receptor type 1 gene variants in the malignant hyperthermia-susceptible population of the United States
Brandom, Barbara W, Bina, Saiid, Wong, Cynthia A, Wallace, Tarina, Visoiu, Mihaela, Isackson, Paul J, Vladutiu, Georgirene D, Sambuughin, Nyamkhishig, Muldoon, Sheila M
Published in Anesthesia and analgesia (01.05.2013)
Published in Anesthesia and analgesia (01.05.2013)
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Coenzyme Q10 supplementation for the treatment of statin-associated muscle symptoms
Chen, Wilson, Ochs-Balcom, Heather M, Ma, Changxing, Isackson, Paul J, Vladutiu, Georgirene D, Luzum, Jasmine A
Published in Future cardiology (01.06.2022)
Published in Future cardiology (01.06.2022)
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RYR1 and CACNA1S genetic variants identified with statin-associated muscle symptoms
Isackson, Paul J, Wang, Jianxin, Zia, Mohammad, Spurgeon, Paul, Levesque, Adrian, Bard, Jonathan, James, Smitha, Nowak, Norma, Lee, Tae Keun, Vladutiu, Georgirene D
Published in Pharmacogenomics (01.11.2018)
Published in Pharmacogenomics (01.11.2018)
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Clinical features related to statin‐associated muscle symptoms
Ochs‐Balcom, Heather M., Nguyen, Ly Minh, Ma, Changxing, Isackson, Paul J., Luzum, Jasmine A., Kitzmiller, Joseph P., Tarnopolsky, Mark, Weisman, Michael, Christopher‐Stine, Lisa, Peltier, Wendy, Wortmann, Robert L., Vladutiu, Georgirene D.
Published in Muscle & nerve (01.05.2019)
Published in Muscle & nerve (01.05.2019)
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Clinical spectrum, morbidity, and mortality in 113 pediatric patients with mitochondrial disease
Scaglia, Fernando, Towbin, Jeffrey A, Craigen, William J, Belmont, John W, Smith, E O'Brian, Neish, Stephen R, Ware, Stephanie M, Hunter, Jill V, Fernbach, Susan D, Vladutiu, Georgirene D, Wong, Lee-Jun C, Vogel, Hannes
Published in Pediatrics (Evanston) (01.10.2004)
Published in Pediatrics (Evanston) (01.10.2004)
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Genetic risk factors associated with lipid-lowering drug-induced myopathies
Vladutiu, Georgirene D., Simmons, Zachary, Isackson, Paul J., Tarnopolsky, Mark, Peltier, Wendy L., Barboi, Alexandru C., Sripathi, Naganand, Wortmann, Robert L., Phillips, Paul S.
Published in Muscle & nerve (01.08.2006)
Published in Muscle & nerve (01.08.2006)
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Statin-associated myopathy with normal creatine kinase levels
PHILLIPS, Paul S, HAAS, Richard H, BANNYKH, Sergei, HATHAWAY, Stephanie, GRAY, Nancy L, KIMURA, Bruce J, VLADUTIU, Georgirene D, ENGLAND, John D. F
Published in Annals of internal medicine (01.10.2002)
Published in Annals of internal medicine (01.10.2002)
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Genetic risk for malignant hyperthermia in non-anesthesia-induced myopathies
Vladutiu, Georgirene D., Isackson, Paul J., Kaufman, Kenneth, Harley, John B., Cobb, Beth, Christopher-Stine, Lisa, Wortmann, Robert L.
Published in Molecular genetics and metabolism (01.09.2011)
Published in Molecular genetics and metabolism (01.09.2011)
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Mitochondrial diseases in North America: An analysis of the NAMDC Registry
Barca, Emanuele, Long, Yuelin, Cooley, Victoria, Schoenaker, Robert, Emmanuele, Valentina, DiMauro, Salvatore, Cohen, Bruce H, Karaa, Amel, Vladutiu, Georgirene D, Haas, Richard, Van Hove, Johan L K, Scaglia, Fernando, Parikh, Sumit, Bedoyan, Jirair K, DeBrosse, Susanne D, Gavrilova, Ralitza H, Saneto, Russell P, Enns, Gregory M, Stacpoole, Peter W, Ganesh, Jaya, Larson, Austin, Zolkipli-Cunningham, Zarazuela, Falk, Marni J, Goldstein, Amy C, Tarnopolsky, Mark, Gropman, Andrea, Camp, Kathryn, Krotoski, Danuta, Engelstad, Kristin, Rosales, Xiomara Q, Kriger, Joshua, Grier, Johnston, Buchsbaum, Richard, Thompson, John L P, Hirano, Michio
Published in Neurology. Genetics (01.04.2020)
Published in Neurology. Genetics (01.04.2020)
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Journal Article
SLCO1B1 Variants and Statin-Induced Myopathy
Vladutiu, Georgirene D, Isackson, Paul J
Published in The New England journal of medicine (15.01.2009)
Published in The New England journal of medicine (15.01.2009)
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