A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model
Kreye, Jakob, Reincke, S. Momsen, Kornau, Hans-Christian, Sánchez-Sendin, Elisa, Corman, Victor Max, Liu, Hejun, Yuan, Meng, Wu, Nicholas C., Zhu, Xueyong, Lee, Chang-Chun D., Trimpert, Jakob, Höltje, Markus, Dietert, Kristina, Stöffler, Laura, von Wardenburg, Niels, van Hoof, Scott, Homeyer, Marie A., Hoffmann, Julius, Abdelgawad, Azza, Gruber, Achim D., Bertzbach, Luca D., Vladimirova, Daria, Li, Lucie Y., Barthel, Paula Charlotte, Skriner, Karl, Hocke, Andreas C., Hippenstiel, Stefan, Witzenrath, Martin, Suttorp, Norbert, Kurth, Florian, Franke, Christiana, Endres, Matthias, Schmitz, Dietmar, Jeworowski, Lara Maria, Richter, Anja, Schmidt, Marie Luisa, Schwarz, Tatjana, Müller, Marcel Alexander, Drosten, Christian, Wendisch, Daniel, Sander, Leif E., Osterrieder, Nikolaus, Wilson, Ian A., Prüss, Harald
Published in Cell (12.11.2020)
Published in Cell (12.11.2020)
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Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters
Osterrieder, Nikolaus, Bertzbach, Luca D, Dietert, Kristina, Abdelgawad, Azza, Vladimirova, Daria, Kunec, Dusan, Hoffmann, Donata, Beer, Martin, Gruber, Achim D, Trimpert, Jakob
Published in Viruses (20.07.2020)
Published in Viruses (20.07.2020)
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The Roborovski Dwarf Hamster Is A Highly Susceptible Model for a Rapid and Fatal Course of SARS-CoV-2 Infection
Trimpert, Jakob, Vladimirova, Daria, Dietert, Kristina, Abdelgawad, Azza, Kunec, Dusan, Dökel, Simon, Voss, Anne, Gruber, Achim D., Bertzbach, Luca D., Osterrieder, Nikolaus
Published in Cell Reports (08.12.2020)
Published in Cell Reports (08.12.2020)
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SARS‐CoV‐2 infection of Chinese hamsters (Cricetulus griseus) reproduces COVID‐19 pneumonia in a well‐established small animal model
Bertzbach, Luca D., Vladimirova, Daria, Dietert, Kristina, Abdelgawad, Azza, Gruber, Achim D., Osterrieder, Nikolaus, Trimpert, Jakob
Published in Transboundary and emerging diseases (01.05.2021)
Published in Transboundary and emerging diseases (01.05.2021)
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Epithelial response to IFN‐γ promotes SARS‐CoV‐2 infection
Heuberger, Julian, Trimpert, Jakob, Vladimirova, Daria, Goosmann, Christian, Lin, Manqiang, Schmuck, Rosa, Mollenkopf, Hans‐Joachim, Brinkmann, Volker, Tacke, Frank, Osterrieder, Nikolaus, Sigal, Michael
Published in EMBO molecular medicine (09.04.2021)
Published in EMBO molecular medicine (09.04.2021)
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Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19
Nouailles, Geraldine, Wyler, Emanuel, Pennitz, Peter, Postmus, Dylan, Vladimirova, Daria, Kazmierski, Julia, Pott, Fabian, Dietert, Kristina, Muelleder, Michael, Farztdinov, Vadim, Obermayer, Benedikt, Wienhold, Sandra-Maria, Andreotti, Sandro, Hoefler, Thomas, Sawitzki, Birgit, Drosten, Christian, Sander, Leif E., Suttorp, Norbert, Ralser, Markus, Beule, Dieter, Gruber, Achim D., Goffinet, Christine, Landthaler, Markus, Trimpert, Jakob, Witzenrath, Martin
Published in Nature communications (11.08.2021)
Published in Nature communications (11.08.2021)
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An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission
Adler, Julia M., Martin Vidal, Ricardo, Langner, Christine, Vladimirova, Daria, Abdelgawad, Azza, Kunecova, Daniela, Lin, Xiaoyuan, Nouailles, Geraldine, Voss, Anne, Kunder, Sandra, Gruber, Achim D., Wu, Haibo, Osterrieder, Nikolaus, Kunec, Dusan, Trimpert, Jakob
Published in Nature communications (02.02.2024)
Published in Nature communications (02.02.2024)
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Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding
Trimpert, Jakob, Dietert, Kristina, Firsching, Theresa C., Ebert, Nadine, Thi Nhu Thao, Tran, Vladimirova, Daria, Kaufer, Susanne, Labroussaa, Fabien, Abdelgawad, Azza, Conradie, Andelé, Höfler, Thomas, Adler, Julia M., Bertzbach, Luca D., Jores, Joerg, Gruber, Achim D., Thiel, Volker, Osterrieder, Nikolaus, Kunec, Dusan
Published in Cell reports (Cambridge) (03.08.2021)
Published in Cell reports (Cambridge) (03.08.2021)
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Early protective effect of a ("pan") coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration
Abdelaziz, Mohammed O, Raftery, Martin J, Weihs, Julian, Bielawski, Olivia, Edel, Richard, Köppke, Julia, Vladimirova, Daria, Adler, Julia M, Firsching, Theresa, Voß, Anne, Gruber, Achim D, Hummel, Luca V, Fernandez Munoz, Ivan, Müller-Marquardt, Francesca, Willimsky, Gerald, Elleboudy, Nooran S, Trimpert, Jakob, Schönrich, Günther
Published in Frontiers in immunology (13.07.2023)
Published in Frontiers in immunology (13.07.2023)
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Deciphering the Role of Humoral and Cellular Immune Responses in Different COVID-19 Vaccines-A Comparison of Vaccine Candidate Genes in Roborovski Dwarf Hamsters
Trimpert, Jakob, Herwig, Susanne, Stein, Julia, Vladimirova, Daria, Adler, Julia M, Abdelgawad, Azza, Firsching, Theresa C, Thoma, Tizia, Sehouli, Jalid, Osterrieder, Klaus, Gruber, Achim D, Sawitzki, Birgit, Sander, Leif Erik, Cichon, Günter
Published in Viruses (16.11.2021)
Published in Viruses (16.11.2021)
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Fabrication of Silica Optical Fibers: Optimal Control Problem Solution
Pervadchuk, Vladimir, Vladimirova, Daria, Gordeeva, Irina, Kuchumov, Alex G., Dektyarev, Dmitrij
Published in Fibers (01.12.2021)
Published in Fibers (01.12.2021)
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Standardization of Reporting Criteria for Lung Pathology in SARS-CoV-2-infected Hamsters: What Matters?
Gruber, Achim D, Osterrieder, Nikolaus, Bertzbach, Luca D, Vladimirova, Daria, Greuel, Selina, Ihlow, Jana, Horst, David, Trimpert, Jakob, Dietert, Kristina
Published in American journal of respiratory cell and molecular biology (01.12.2020)
Published in American journal of respiratory cell and molecular biology (01.12.2020)
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A non-transmissible live attenuated SARS-CoV-2 vaccine
Adler, Julia M., Martin Vidal, Ricardo, Voß, Anne, Kunder, Sandra, Nascimento, Mariana, Abdelgawad, Azza, Langner, Christine, Vladimirova, Daria, Osterrieder, Nikolaus, Gruber, Achim D., Kunec, Dusan, Trimpert, Jakob
Published in Molecular therapy (02.08.2023)
Published in Molecular therapy (02.08.2023)
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Antigenic cartography using variant-specific hamster sera reveals substantial antigenic variation among Omicron subvariants
Mühlemann, Barbara, Trimpert, Jakob, Walper, Felix, Schmidt, Marie L, Jansen, Jenny, Schroeder, Simon, Jeworowski, Lara M, Beheim-Schwarzbach, Jörn, Bleicker, Tobias, Niemeyer, Daniela, Richter, Anja, Adler, Julia M, Vidal, Ricardo Martin, Langner, Christine, Vladimirova, Daria, Wilks, Samuel H, Smith, Derek J, Voß, Mathias, Paltzow, Lea, Martínez Christophersen, Christina, Rose, Ruben, Krumbholz, Andi, Jones, Terry C, Corman, Victor M, Drosten, Christian
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2024)
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Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease
Friedrich, Vincent D., Pennitz, Peter, Wyler, Emanuel, Adler, Julia M., Postmus, Dylan, Müller, Kristina, Teixeira Alves, Luiz Gustavo, Prigann, Julia, Pott, Fabian, Vladimirova, Daria, Hoefler, Thomas, Goekeri, Cengiz, Landthaler, Markus, Goffinet, Christine, Saliba, Antoine-Emmanuel, Scholz, Markus, Witzenrath, Martin, Trimpert, Jakob, Kirsten, Holger, Nouailles, Geraldine
Published in EBioMedicine (01.10.2024)
Published in EBioMedicine (01.10.2024)
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Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human diseaseResearch in context
Vincent D. Friedrich, Peter Pennitz, Emanuel Wyler, Julia M. Adler, Dylan Postmus, Kristina Müller, Luiz Gustavo Teixeira Alves, Julia Prigann, Fabian Pott, Daria Vladimirova, Thomas Hoefler, Cengiz Goekeri, Markus Landthaler, Christine Goffinet, Antoine-Emmanuel Saliba, Markus Scholz, Martin Witzenrath, Jakob Trimpert, Holger Kirsten, Geraldine Nouailles
Published in EBioMedicine (01.10.2024)
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Published in EBioMedicine (01.10.2024)
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