Impact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials
Schwaederle, Maria, Zhao, Melissa, Lee, J Jack, Eggermont, Alexander M, Schilsky, Richard L, Mendelsohn, John, Lazar, Vladimir, Kurzrock, Razelle
Published in Journal of clinical oncology (10.11.2015)
Published in Journal of clinical oncology (10.11.2015)
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Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial
Rodon, Jordi, Soria, Jean-Charles, Berger, Raanan, Miller, Wilson H., Rubin, Eitan, Kugel, Aleksandra, Tsimberidou, Apostolia, Saintigny, Pierre, Ackerstein, Aliza, Braña, Irene, Loriot, Yohann, Afshar, Mohammad, Miller, Vincent, Wunder, Fanny, Bresson, Catherine, Martini, Jean-François, Raynaud, Jacques, Mendelsohn, John, Batist, Gerald, Onn, Amir, Tabernero, Josep, Schilsky, Richard L., Lazar, Vladimir, Lee, J. Jack, Kurzrock, Razelle
Published in Nature Medicine (01.05.2019)
Published in Nature Medicine (01.05.2019)
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High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial
Massard, Christophe, Michiels, Stefan, Ferté, Charles, Le Deley, Marie-Cécile, Lacroix, Ludovic, Hollebecque, Antoine, Verlingue, Loic, Ileana, Ecaterina, Rosellini, Silvia, Ammari, Samy, Ngo-Camus, Maud, Bahleda, Rastislav, Gazzah, Anas, Varga, Andrea, Postel-Vinay, Sophie, Loriot, Yohann, Even, Caroline, Breuskin, Ingrid, Auger, Nathalie, Job, Bastien, De Baere, Thierry, Deschamps, Frederic, Vielh, Philippe, Scoazec, Jean-Yves, Lazar, Vladimir, Richon, Catherine, Ribrag, Vincent, Deutsch, Eric, Angevin, Eric, Vassal, Gilles, Eggermont, Alexander, André, Fabrice, Soria, Jean-Charles
Published in Cancer discovery (01.06.2017)
Published in Cancer discovery (01.06.2017)
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Impact of a Biomarker-Based Strategy on Oncology Drug Development: A Meta-analysis of Clinical Trials Leading to FDA Approval
Jardim, Denis L, Fontes Jardim, Denis L, Schwaederle, Maria, Wei, Caimiao, Lee, J Jack, Hong, David S, Eggermont, Alexander M, Schilsky, Richard L, Mendelsohn, John, Lazar, Vladimir, Kurzrock, Razelle
Published in JNCI : Journal of the National Cancer Institute (01.11.2015)
Published in JNCI : Journal of the National Cancer Institute (01.11.2015)
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An Immunosurveillance Mechanism Controls Cancer Cell Ploidy
Senovilla, Laura, Vitale, Ilio, Martins, Isabelle, Tailler, Maximilien, Pailleret, Claire, Michaud, Mickaël, Galluzzi, Lorenzo, Adjemian, Sandy, Kepp, Oliver, Niso-Santano, Mireia, Shen, Shensi, Mariño, Guillermo, Criollo, Alfredo, Boilève, Alice, Job, Bastien, Ladoire, Sylvain, Ghiringhelli, François, Sistigu, Antonella, Yamazaki, Takahiro, Rello-Varona, Santiago, Locher, Clara, Poirier-Colame, Vichnou, Talbot, Monique, Valent, Alexander, Berardinelli, Francesco, Antoccia, Antonio, Ciccosanti, Fabiola, Fimia, Gian Maria, Piacentini, Mauro, Fueyo, Antonio, Messina, Nicole L., Li, Ming, Chan, Christopher J., Sigl, Verena, Pourcher, Guillaume, Ruckenstuhl, Christoph, Carmona-Gutierrez, Didac, Lazar, Vladimir, Penninger, Josef M., Madeo, Frank, López-Otín, Carlos, Smyth, Mark J., Zitvogel, Laurence, Castedo, Maria, Kroemer, Guido
Published in Science (American Association for the Advancement of Science) (28.09.2012)
Published in Science (American Association for the Advancement of Science) (28.09.2012)
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miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death
GALLUZZI, Lorenzo, MORSELLI, Eugenia, RIPOCHE, Hugues, LAZAR, Vladimir, HAREL-BELLAN, Annick, DESSEN, Philippe, BARILLOT, Emmanuel, KROEMER, Guido, VITALE, Ilio, KEPP, Oliver, SENOVILLA, Laura, CRIOLLO, Alfredo, SERVANT, Nicolas, PACCARD, Caroline, HUPE, Philippe, ROBERT, Thomas
Published in Cancer research (Chicago, Ill.) (01.03.2010)
Published in Cancer research (Chicago, Ill.) (01.03.2010)
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Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas
Puget, Stephanie, Philippe, Cathy, Bax, Dorine A, Job, Bastien, Varlet, Pascale, Junier, Marie-Pierre, Andreiuolo, Felipe, Carvalho, Dina, Reis, Ricardo, Guerrini-Rousseau, Lea, Roujeau, Thomas, Dessen, Philippe, Richon, Catherine, Lazar, Vladimir, Le Teuff, Gwenael, Sainte-Rose, Christian, Geoerger, Birgit, Vassal, Gilles, Jones, Chris, Grill, Jacques
Published in PloS one (28.02.2012)
Published in PloS one (28.02.2012)
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Next-Generation Sequencing Reveals High Concordance of Recurrent Somatic Alterations Between Primary Tumor and Metastases From Patients With Non–Small-Cell Lung Cancer
VIGNOT, Stéphane, FRAMPTON, Garrett M, ANDRE, Fabrice, STEPHENS, Philip J, LAZAR, Vladimir, MILLER, Vincent A, BRAMBILLA, Elisabeth, SORIA, Jean-Charles, YELENSKY, Roman, COMMO, Frédéric, BRAMBILLA, Christian, PALMER, Gary, MORO-SIBILOT, Denis, ROSS, Jeffrey S, CRONIN, Maureen T
Published in Journal of clinical oncology (10.06.2013)
Published in Journal of clinical oncology (10.06.2013)
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SERS-based differential diagnosis between multiple solid malignancies: breast, colorectal, lung, ovarian and oral cancer
Moisoiu, Vlad, Stefancu, Andrei, Gulei, Diana, Boitor, Radu, Magdo, Lorand, Raduly, Lajos, Pasca, Sergiu, Kubelac, Paul, Mehterov, Nikolay, Chiș, Vasile, Simon, Marioara, Muresan, Mihai, Irimie, Alexandra Iulia, Baciut, Mihaela, Stiufiuc, Rares, Pavel, Ioana E, Achimas-Cadariu, Patriciu, Ionescu, Calin, Lazar, Vladimir, Sarafian, Victoria, Notingher, Ioan, Leopold, Nicolae, Berindan-Neagoe, Ioana
Published in International journal of nanomedicine (01.08.2019)
Published in International journal of nanomedicine (01.08.2019)
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Molecular Characterization of Breast Cancer with High-Resolution Oligonucleotide Comparative Genomic Hybridization Array
ANDRE, Fabrice, JOB, Bastien, DELALOGE, Suzette, HORTOBAGYI, Gabriel N, SYMMANS, W. Fraser, LAZAR, Vladimir, PUSZTAI, Lajos, DESSEN, Philippe, TORDAI, Attila, MICHIELS, Stefan, LIEDTKE, Cornelia, RICHON, Catherine, KAI YAN, BAILANG WANG, VASSAL, Gilles
Published in Clinical cancer research (15.01.2009)
Published in Clinical cancer research (15.01.2009)
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Network enrichment analysis: extension of gene-set enrichment analysis to gene networks
Alexeyenko, Andrey, Lee, Woojoo, Pernemalm, Maria, Guegan, Justin, Dessen, Philippe, Lazar, Vladimir, Lehtiö, Janne, Pawitan, Yudi
Published in BMC bioinformatics (11.09.2012)
Published in BMC bioinformatics (11.09.2012)
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Targeting the Deregulated Spliceosome Core Machinery in Cancer Cells Triggers mTOR Blockade and Autophagy
QUIDVILLE, Virginie, ALSAFADI, Samar, DELALOGE, Suzette, SAGHATCHIAN, Mahasti, PAUTIER, Patricia, MORICE, Philippe, DESSEN, Philippe, VAGNER, Stephan, ANDRE, Fabrice, GOUBAR, Aïcha, COMMO, Frédéric, SCOTT, Véronique, PIOCHE-DURIEU, Catherine, GIRAULT, Isabelle, BACONNAIS, Sonia, LE CAM, Eric, LAZAR, Vladimir
Published in Cancer research (Chicago, Ill.) (01.04.2013)
Published in Cancer research (Chicago, Ill.) (01.04.2013)
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Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome
Winnepenninckx, Véronique, Lazar, Vladimir, Michiels, Stefan, Dessen, Philippe, Stas, Marguerite, Alonso, Soledad R., Avril, Marie-Françoise, Ortiz Romero, Pablo L., Robert, Thomas, Balacescu, Ovidiu, Eggermont, Alexander M. M., Lenoir, Gilbert, Sarasin, Alain, Tursz, Thomas, van den Oord, Joost J., Spatz, Alain
Published in JNCI : Journal of the National Cancer Institute (05.04.2006)
Published in JNCI : Journal of the National Cancer Institute (05.04.2006)
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Adipocyte-Based Cell Therapy in Oncology: The Role of Cancer-Associated Adipocytes and Their Reinterpretation as Delivery Platforms
Munteanu, Raluca, Onaciu, Anca, Moldovan, Cristian, Zimta, Alina-Andreea, Gulei, Diana, Paradiso, Angelo V, Lazar, Vladimir, Berindan-Neagoe, Ioana
Published in Pharmaceutics (28.04.2020)
Published in Pharmaceutics (28.04.2020)
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Identification of a central network hub of key prognostic genes based on correlation between transcriptomics and survival in patients with metastatic solid tumors
Lazar, Vladimir, Raymond, Eric, Magidi, Shai, Bresson, Catherine, Wunder, Fanny, Berindan-Neagoe, Ioana, Tijeras-Rabaland, Annemilaï, Raynaud, Jacques, Onn, Amir, Ducreux, Michel, Batist, Gerald, Lassen, Ulrik, Cilius Nielsen, Fin, Schilsky, Richard L, Rubin, Eitan, Kurzrock, Razelle
Published in Therapeutic advances in medical oncology (01.01.2024)
Published in Therapeutic advances in medical oncology (01.01.2024)
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Tumor Tissue Explant Culture of Patient-Derived Xenograft as Potential Prioritization Tool for Targeted Therapy
Ghosh, Susmita, Prasad, Manu, Kundu, Kiran, Cohen, Limor, Yegodayev, Ksenia M, Zorea, Jonathan, Joshua, Ben-Zion, Lasry, Batel, Dimitstein, Orr, Bahat-Dinur, Anat, Mizrachi, Aviram, Lazar, Vladimir, Elkabets, Moshe, Porgador, Angel
Published in Frontiers in oncology (22.01.2019)
Published in Frontiers in oncology (22.01.2019)
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Chk1 as a new therapeutic target in triple-negative breast cancer
Albiges, Laurence, Goubar, Aïcha, Scott, Véronique, Vicier, Cécile, Lefèbvre, Céline, Alsafadi, Samar, Commo, Frédéric, Saghatchian, Mahasti, Lazar, Vladimir, Dessen, Philippe, Delaloge, Suzette, André, Fabrice, Quidville, Virginie
Published in Breast (Edinburgh) (01.06.2014)
Published in Breast (Edinburgh) (01.06.2014)
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A WIN Consortium phase I study exploring avelumab, palbociclib, and axitinib in advanced non‐small cell lung cancer
Solomon, Benjamin, Callejo, Ana, Bar, Jair, Berchem, Guy, Bazhenova, Lyudmila, Saintigny, Pierre, Wunder, Fanny, Raynaud, Jacques, Girard, Nicolas, Lee, J. Jack, Sulaiman, Raed, Prouse, Bruce, Bresson, Catherine, Ventura, Hila, Magidi, Shai, Rubin, Eitan, Young, Brandon, Onn, Amir, Leyland‐Jones, Brian, Schilsky, Richard L., Lazar, Vladimir, Felip, Enriqueta, Kurzrock, Razelle
Published in Cancer medicine (Malden, MA) (01.07.2022)
Published in Cancer medicine (Malden, MA) (01.07.2022)
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A transcriptomics approach to expand therapeutic options and optimize clinical trials in oncology
Lazar, Vladimir, Zhang, Baolin, Magidi, Shai, Le Tourneau, Christophe, Raymond, Eric, Ducreux, Michel, Bresson, Catherine, Raynaud, Jacques, Wunder, Fanny, Onn, Amir, Felip, Enriqueta, Tabernero, Josep, Batist, Gerald, Kurzrock, Razelle, Rubin, Eitan, Schilsky, Richard L.
Published in Therapeutic advances in medical oncology (01.01.2023)
Published in Therapeutic advances in medical oncology (01.01.2023)
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The THAP–zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes
Cayrol, Corinne, Lacroix, Chrystelle, Mathe, Catherine, Ecochard, Vincent, Ceribelli, Michele, Loreau, Emilie, Lazar, Vladimir, Dessen, Philippe, Mantovani, Roberto, Aguilar, Luc, Girard, Jean-Philippe
Published in Blood (15.01.2007)
Published in Blood (15.01.2007)
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