Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease
Gomez‐Arboledas, Angela, Davila, Jose C., Sanchez‐Mejias, Elisabeth, Navarro, Victoria, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Sanchez‐Mico, Maria Virtudes, Trujillo‐Estrada, Laura, Fernandez‐Valenzuela, Juan Jose, Vizuete, Marisa, Comella, Joan X., Galea, Elena, Vitorica, Javier, Gutierrez, Antonia
Published in Glia (01.03.2018)
Published in Glia (01.03.2018)
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Journal Article
Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration
Sanchez-Mejias, Elisabeth, Navarro, Victoria, Jimenez, Sebastian, Sanchez-Mico, Maria, Sanchez-Varo, Raquel, Nuñez-Diaz, Cristina, Trujillo-Estrada, Laura, Davila, Jose Carlos, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Acta neuropathologica (01.12.2016)
Published in Acta neuropathologica (01.12.2016)
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Journal Article
Microglia in Alzheimer's Disease: Activated, Dysfunctional or Degenerative
Navarro, Victoria, Sanchez-Mejias, Elisabeth, Jimenez, Sebastian, Muñoz-Castro, Clara, Sanchez-Varo, Raquel, Davila, Jose C, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Frontiers in aging neuroscience (11.05.2018)
Published in Frontiers in aging neuroscience (11.05.2018)
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Journal Article
Transgenic Mouse Models of Alzheimer's Disease: An Integrative Analysis
Sanchez-Varo, Raquel, Mejias-Ortega, Marina, Fernandez-Valenzuela, Juan Jose, Nuñez-Diaz, Cristina, Caceres-Palomo, Laura, Vegas-Gomez, Laura, Sanchez-Mejias, Elisabeth, Trujillo-Estrada, Laura, Garcia-Leon, Juan Antonio, Moreno-Gonzalez, Ines, Vizuete, Marisa, Vitorica, Javier, Baglietto-Vargas, David, Gutierrez, Antonia
Published in International journal of molecular sciences (12.05.2022)
Published in International journal of molecular sciences (12.05.2022)
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Journal Article
Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model
Fernandez-Valenzuela, Juan Jose, Sanchez-Varo, Raquel, Muñoz-Castro, Clara, De Castro, Vanessa, Sanchez-Mejias, Elisabeth, Navarro, Victoria, Jimenez, Sebastian, Nuñez-Diaz, Cristina, Gomez-Arboledas, Angela, Moreno-Gonzalez, Ines, Vizuete, Marisa, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia
Published in Scientific reports (08.09.2020)
Published in Scientific reports (08.09.2020)
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Journal Article
Should We Open Fire on Microglia? Depletion Models as Tools to Elucidate Microglial Role in Health and Alzheimer's Disease
Romero-Molina, Carmen, Navarro, Victoria, Jimenez, Sebastian, Muñoz-Castro, Clara, Sanchez-Mico, Maria V, Gutierrez, Antonia, Vitorica, Javier, Vizuete, Marisa
Published in International journal of molecular sciences (08.09.2021)
Published in International journal of molecular sciences (08.09.2021)
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Journal Article
Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis
Sanchez-Varo, Raquel, Sanchez-Mejias, Elisabeth, Fernandez-Valenzuela, Juan Jose, De Castro, Vanessa, Mejias-Ortega, Marina, Gomez-Arboledas, Angela, Jimenez, Sebastian, Sanchez-Mico, Maria Virtudes, Trujillo-Estrada, Laura, Moreno-Gonzalez, Ines, Baglietto-Vargas, David, Vizuete, Marisa, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia
Published in Frontiers in neuroscience (04.11.2021)
Published in Frontiers in neuroscience (04.11.2021)
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Journal Article
Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer's disease hippocampus
Muñoz-Castro, Clara, Mejias-Ortega, Marina, Sanchez-Mejias, Elisabeth, Navarro, Victoria, Trujillo-Estrada, Laura, Jimenez, Sebastian, Garcia-Leon, Juan Antonio, Fernandez-Valenzuela, Juan Jose, Sanchez-Mico, Maria Virtudes, Romero-Molina, Carmen, Moreno-Gonzalez, Ines, Baglietto-Vargas, David, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Acta neuropathologica communications (28.02.2023)
Published in Acta neuropathologica communications (28.02.2023)
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Journal Article
PERIPHERAL MYELOID CELLS INFILTRATE THE HIPPOCAMPUS OF ALZHEIMER´S DISEASE PATIENTS
Mejias-Ortega, Marina, Muñoz-Castro, Clara, Sanchez-Mejias, Elisabet, Jimenez, Sebastian, Trujillo-Estrada, Laura, Vizuete, Marisa, Vitorica, Javier, Gutierrez, Antonia
Published in IBRO neuroscience reports (01.10.2023)
Published in IBRO neuroscience reports (01.10.2023)
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Journal Article
Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus
Torres, Manuel, Jimenez, Sebastian, Sanchez-Varo, Raquel, Navarro, Victoria, Trujillo-Estrada, Laura, Sanchez-Mejias, Elisabeth, Carmona, Irene, Davila, Jose Carlos, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Molecular neurodegeneration (22.11.2012)
Published in Molecular neurodegeneration (22.11.2012)
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Journal Article
Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo
Serrano-Pozo, Alberto, Sánchez-García, Manuel A, Heras-Garvín, Antonio, March-Díaz, Rosana, Navarro, Victoria, Vizuete, Marisa, López-Barneo, José, Vitorica, Javier, Pascual, Alberto
Published in PloS one (01.01.2017)
Published in PloS one (01.01.2017)
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Journal Article
Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology
Romero-Molina, Carmen, Navarro, Victoria, Sanchez-Varo, Raquel, Jimenez, Sebastian, Fernandez-Valenzuela, Juan J, Sanchez-Mico, Maria V, Muñoz-Castro, Clara, Gutierrez, Antonia, Vitorica, Javier, Vizuete, Marisa
Published in Frontiers in cellular neuroscience (14.11.2018)
Published in Frontiers in cellular neuroscience (14.11.2018)
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Journal Article
Disruption of amyloid plaques integrity affects the soluble oligomers content from Alzheimer disease brains
Jimenez, Sebastian, Navarro, Victoria, Moyano, Javier, Sanchez-Mico, María, Torres, Manuel, Davila, Jose Carlos, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in PloS one (08.12.2014)
Published in PloS one (08.12.2014)
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Journal Article
Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model
Jimenez, Sebastian, Torres, Manuel, Vizuete, Marisa, Sanchez-Varo, Raquel, Sanchez-Mejias, Elisabeth, Trujillo-Estrada, Laura, Carmona-Cuenca, Irene, Caballero, Cristina, Ruano, Diego, Gutierrez, Antonia, Vitorica, Javier
Published in The Journal of biological chemistry (27.05.2011)
Published in The Journal of biological chemistry (27.05.2011)
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Journal Article
MONOCYTE‐DERIVED CELLS INVADE AMYLOID PLAQUES IN HUMAN ALZHEIMER’S DISEASE HIPPOCAMPUS
Mejias‐Ortega, Marina, Muñoz‐Castro, Clara, Sanchez‐Mejias, Elisabeth, Jimenez, Sebastian, Trujillo‐Estrada, Laura, Vizuete, Marisa, Vitorica, Javier, Gutierrez, Antonia
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease
Sanchez‐Mico, Maria V., Jimenez, Sebastian, Gomez‐Arboledas, Angela, Muñoz‐Castro, Clara, Romero‐Molina, Carmen, Navarro, Victoria, Sanchez‐Mejias, Elisabeth, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Galea, Elena, Davila, José C., Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Glia (01.04.2021)
Published in Glia (01.04.2021)
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Journal Article
Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus
Sanchez-Varo, Raquel, Trujillo-Estrada, Laura, Sanchez-Mejias, Elisabeth, Torres, Manuel, Baglietto-Vargas, David, Moreno-Gonzalez, Ines, De Castro, Vanessa, Jimenez, Sebastian, Ruano, Diego, Vizuete, Marisa, Davila, Jose Carlos, Garcia-Verdugo, Jose Manuel, Jimenez, Antonio Jesus, Vitorica, Javier, Gutierrez, Antonia
Published in Acta neuropathologica (01.01.2012)
Published in Acta neuropathologica (01.01.2012)
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Journal Article
Cover Image, Volume 69, Issue 4
Sanchez‐Mico, Maria V., Jimenez, Sebastian, Gomez‐Arboledas, Angela, Muñoz‐Castro, Clara, Romero‐Molina, Carmen, Navarro, Victoria, Sanchez‐Mejias, Elisabeth, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Galea, Elena, Davila, José C., Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Glia (01.04.2021)
Published in Glia (01.04.2021)
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Journal Article
Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease
Baglietto-Vargas, David, Sánchez-Mejias, Elisabeth, Navarro, Victoria, Jimenez, Sebastián, Trujillo-Estrada, Laura, Gómez-Arboledas, Angela, Sánchez-Mico, Maria, Sánchez-Varo, Raquel, Vizuete, Marisa, Dávila, José Carlos, García-Verdugo, José Manuel, Vitorica, Javier, Gutierrez, Antonia
Published in Scientific reports (30.08.2017)
Published in Scientific reports (30.08.2017)
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Journal Article
Early Neuronal Loss and Axonal/Presynaptic Damage is Associated with Accelerated Amyloid-β Accumulation in AβPP/PS1 Alzheimer's Disease Mice Subiculum
Trujillo-Estrada, Laura, Dávila, José Carlos, Sánchez-Mejias, Elisabeth, Sánchez-Varo, Raquel, Gomez-Arboledas, Angela, Vizuete, Marisa, Vitorica, Javier, Gutiérrez, Antonia
Published in Journal of Alzheimer's disease (01.01.2014)
Published in Journal of Alzheimer's disease (01.01.2014)
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Journal Article