Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4
van den Bulk, Jitske, Verdegaal, Els M E, Ruano, Dina, Ijsselsteijn, Marieke E, Visser, Marten, van der Breggen, Ruud, Duhen, Thomas, van der Ploeg, Manon, de Vries, Natasja L, Oosting, Jan, Peeters, Koen C M J, Weinberg, Andrew D, Farina-Sarasqueta, Arantza, van der Burg, Sjoerd H, de Miranda, Noel F C C
Published in Genome medicine (30.12.2019)
Published in Genome medicine (30.12.2019)
Get full text
Journal Article
Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S
Harryvan, Tom J, Visser, Marten, de Bruin, Linda, Plug, Léonie, Griffioen, Lisa, Mulder, Arend, van Veelen, Peter A, van der Heden van Noort, Gerbrand J, Jongsma, Marlieke LM, Meeuwsen, Miranda H, Wiertz, Emmanuel JHJ, Santegoets, Saskia J, Hardwick, James CH, Van Hall, Thorbald, Neefjes, Jacques, Van der Burg, Sjoerd H, Hawinkels, Lukas JAC, Verdegaal, Els ME
Published in Journal for immunotherapy of cancer (01.03.2022)
Published in Journal for immunotherapy of cancer (01.03.2022)
Get full text
Journal Article
Timed adoptive T cell transfer during chemotherapy in patients with recurrent platinum-sensitive epithelial ovarian cancer
Verdegaal, Els M E, Santegoets, Saskia J, Welters, Marij J P, de Bruin, Linda, Visser, Marten, van der Minne, Caroline E, de Kok, Pita M, Loof, Nikki M, Boekestijn, Sanne, Roozen, Inge, Westra, Inge M, Meij, Pauline, Van der Burg, Sjoerd H, Kroep, Judith R
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
Get full text
Journal Article
Phase I/II study protocol to assess safety and efficacy of adoptive cell therapy with anti-PD-1 plus low-dose pegylated-interferon-alpha in patients with metastatic melanoma refractory to standard of care treatments: the ACTME trial
van der Kooij, Monique K, Verdegaal, Els M E, Visser, Marten, de Bruin, Linda, van der Minne, Caroline E, Meij, Pauline M, Roozen, Inge C F M, Jonker, Mare A, van den Bosch, Shelley, Liefers, Gerrit-Jan, Speetjens, Frank M, van der Burg, Sjoerd H, Kapiteijn, Ellen
Published in BMJ open (24.11.2020)
Published in BMJ open (24.11.2020)
Get full text
Journal Article
Low-dose interferon-alpha preconditioning and adoptive cell therapy in patients with metastatic melanoma refractory to standard (immune) therapies: a phase I/II study
Verdegaal, Els, van der Kooij, Monique K, Visser, Marten, van der Minne, Caroline, de Bruin, Linda, Meij, Pauline, Terwisscha van Scheltinga, Anton, Welters, Marij J, Santegoets, Saskia, de Miranda, Noel, Roozen, Inge, Liefers, Gerrit Jan, Kapiteijn, Ellen, van der Burg, Sjoerd H
Published in Journal for immunotherapy of cancer (01.03.2020)
Published in Journal for immunotherapy of cancer (01.03.2020)
Get full text
Journal Article
Tumor-Infiltrating T Cells Can Be Expanded Successfully from Primary Uveal Melanoma after Separation from Their Tumor Environment
Gezgin, Gülçin, Visser, Marten, Ruano, Dina, Santegoets, Saskia J., de Miranda, Noel F.C.C., van der Velden, Pieter A., Luyten, Gregorius P.M., van der Burg, Sjoerd H., Verdegaal, Els M., Jager, Martine J.
Published in Ophthalmology science (Online) (01.06.2022)
Published in Ophthalmology science (Online) (01.06.2022)
Get full text
Journal Article
High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
Linnemann, Carsten, van Buuren, Marit M, Bies, Laura, Verdegaal, Els M E, Schotte, Remko, Calis, Jorg J A, Behjati, Sam, Velds, Arno, Hilkmann, Henk, Atmioui, Dris el, Visser, Marten, Stratton, Michael R, Haanen, John B A G, Spits, Hergen, van der Burg, Sjoerd H, Schumacher, Ton N M
Published in Nature medicine (01.01.2015)
Published in Nature medicine (01.01.2015)
Get full text
Journal Article
Neoantigen landscape dynamics during human melanoma–T cell interactions
Verdegaal, Els M. E., de Miranda, Noel F. C. C., Visser, Marten, Harryvan, Tom, van Buuren, Marit M., Andersen, Rikke S., Hadrup, Sine R., van der Minne, Caroline E., Schotte, Remko, Spits, Hergen, Haanen, John B. A. G., Kapiteijn, Ellen H. W., Schumacher, Ton N., van der Burg, Sjoerd H.
Published in Nature (London) (04.08.2016)
Published in Nature (London) (04.08.2016)
Get full text
Journal Article
Neoantigen targetability in progressive advanced melanoma
van den Bulk, Jitske, Verdegaal, Els M E, van der Ploeg, Manon, Visser, Marten, Nunes, Joana B, de Ru, Arnoud H, Tjokrodirijo, Rayman T N, Ijsselsteijn, Marieke E, Janssen, Natasja I, van der Breggen, Ruud, de Bruin, Linda, de Kok, Pita, Janssen, George M C, Ruano, Dina, Kapiteijn, Ellen H W, van Veelen, Peter A, de Miranda, Noel F C C, van der Burg, Sjoerd H
Published in Clinical cancer research (13.10.2023)
Published in Clinical cancer research (13.10.2023)
Get full text
Journal Article
IDO and galectin-3 hamper the ex vivo generation of clinical grade tumor-specific T cells for adoptive cell therapy in metastatic melanoma
Melief, Sara M., Visser, Marten, van der Burg, Sjoerd H., Verdegaal, Els M. E.
Published in Cancer Immunology, Immunotherapy (01.07.2017)
Published in Cancer Immunology, Immunotherapy (01.07.2017)
Get full text
Journal Article
Abstract CT194: Low-dose Interferon-alpha pre-conditioning and adoptive cell therapy in metastatic melanoma patients refractory to standard (immune) therapies - a phase 1/2 study
van der Kooij, Monique K., Verdegaal, Els M., Visser, Marten, van der Minne, Carolien E., de Bruin, Linda, Meij, Pauline, van Scheltinga, Anton G. Terwisscha, Welters, Marij J., Santegoets, Saskia J., de Miranda, Noel F., Roozen, Inge C., Liefers, Gerrit-Jan, Kapiteijn, Ellen, van der Burg, Sjoerd H.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Get full text
Journal Article
Inhibition of the type I immune responses of human monocytes by IFN-α and IFN-β
de Paus, Roelof A., van Wengen, Annelies, Schmidt, Iris, Visser, Marten, Verdegaal, Els M.E., van Dissel, Jaap T., van de Vosse, Esther
Published in Cytokine (Philadelphia, Pa.) (01.02.2013)
Published in Cytokine (Philadelphia, Pa.) (01.02.2013)
Get full text
Journal Article
Simplified Monopalmitoyl Toll‐like Receptor 2 Ligand Mini‐UPam for Self‐Adjuvanting Neoantigen‐Based Synthetic Cancer Vaccines
Ende, Thomas C., Heuts, Jeroen M. M., Gential, Geoffroy P. P., Visser, Marten, Graaff, Michel J., Ho, Nataschja I., Jiskoot, Wim, Valentijn, A. Rob P. M., Meeuwenoord, Nico J., Overkleeft, Herman S., Codée, Jeroen D. C., Burg, Sjoerd H., Verdegaal, Els M. E., Marel, Gijsbert A., Ossendorp, Ferry, Filippov, Dmitri V.
Published in Chembiochem : a European journal of chemical biology (06.04.2021)
Published in Chembiochem : a European journal of chemical biology (06.04.2021)
Get full text
Journal Article
343 Identification of tumor-reactive T cells targeting melanoma Dark Antigens™ validates this novel class of targets for development of immunotherapies
Abbott, Rachel, Hofland, Tom, Hulen, Thomas, Elizabeth (Els) Verdegaal, Crowther, Michael, Dukes, Joseph, Khan, Shawez, Pita de Kok, Masi, Giulia, Özcan Met, Schina, Aimilia, Selvadurai, Hayden, Visser, Marten, Ward, Katarzyna, van der Burg, Sjoerd, Kassiotis, George, Svane, Inge
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
Get full text
Journal Article
Erratum: Corrigendum: High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
Linnemann, Carsten, van Buuren, Marit M, Bies, Laura, Verdegaal, Els M E, Schotte, Remko, Calis, Jorg J A, Behjati, Sam, Velds, Arno, Hilkmann, Henk, el Atmioui, Dris, Visser, Marten, Stratton, Michael R, Haanen, John B A G, Spits, Hergen, van der Burg, Sjoerd H, Schumacher, Ton N M
Published in Nature medicine (06.10.2016)
Published in Nature medicine (06.10.2016)
Get full text
Journal Article
Corrigendum: High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4 + T cells in human melanoma
Linnemann, Carsten, van Buuren, Marit M, Bies, Laura, Verdegaal, Els M E, Schotte, Remko, Calis, Jorg J A, Behjati, Sam, Velds, Arno, Hilkmann, Henk, El Atmioui, Dris, Visser, Marten, Stratton, Michael R, Haanen, John B A G, Spits, Hergen, van der Burg, Sjoerd H, Schumacher, Ton N M
Published in Nature medicine (01.10.2016)
Published in Nature medicine (01.10.2016)
Get full text
Journal Article
Successful treatment of metastatic melanoma by adoptive transfer of blood-derived polyclonal tumor-specific CD4+ and CD8+ T cells in combination with low-dose interferon-alpha
Verdegaal, Els M. E., Visser, Marten, Ramwadhdoebé, Tamara H., van der Minne, Caroline E., van Steijn, Jeanne A. Q. M. J., Kapiteijn, Ellen, Haanen, John B. A. G., van der Burg, Sjoerd H., Nortier, Johan W. R., Osanto, Susanne
Published in Cancer Immunology, Immunotherapy (01.07.2011)
Published in Cancer Immunology, Immunotherapy (01.07.2011)
Get full text
Journal Article
Correction: Corrigendum: High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
Linnemann, Carsten, van Buuren, Marit M, Bies, Laura, Verdegaal, Els M E, Schotte, Remko, Calis, Jorg J A, Behjati, Sam, Velds, Arno, Hilkmann, Henk, el Atmioui, Dris, Visser, Marten, Stratton, Michael R, Haanen, John B A G, Spits, Hergen, van der Burg, Sjoerd H, Schumacher, Ton N M
Published in Nature medicine (2016)
Published in Nature medicine (2016)
Get full text
Journal Article
Long-term Survival and Clinical Benefit from Adoptive T-cell Transfer in Stage IV Melanoma Patients Is Determined by a Four-Parameter Tumor Immune Signature
Melief, Sara M, Visconti, Valeria V, Visser, Marten, van Diepen, Merel, Kapiteijn, Ellen H W, van den Berg, Joost H, Haanen, John B A G, Smit, Vincent T H B M, Oosting, Jan, van der Burg, Sjoerd H, Verdegaal, Els M E
Published in Cancer immunology research (01.02.2017)
Published in Cancer immunology research (01.02.2017)
Get more information
Journal Article
High-throughput epitope discovery reveals frequent recognition of neo-antigens by [CD4.sup.+] T cells in human melanoma
Linnemann, Carsten, van Buuren, Marit M, Bies, Laura, Verdegaal, Els M.E, Schotte, Remko, Calis, Jorg J.A, Behjati, Sam, Velds, Arno, Hilkmann, Henk, el Atmioui, Dris, Visser, Marten, Stratton, Michael R, Haanen, John B.A.G, Spits, Hergen, van der Burg, Sjoerd H, Schumacher, Ton N.M
Published in Nature medicine (01.01.2015)
Get full text
Published in Nature medicine (01.01.2015)
Journal Article