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Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

by Abou-Khalil, Bassel, Auce, Pauls, Avbersek, Andreja, Bahlo, Melanie, Balding, David J., Bast, Thomas, Baum, Larry, Becker, Albert J., Becker, Felicitas, Berghuis, Bianca, Berkovic, Samuel F., Boysen, Katja E., Bradfield, Jonathan P., Brody, Lawrence C., Buono, Russell J., Campbell, Ellen, Cascino, Gregory D., Catarino, Claudia B., Cavalleri, Gianpiero L., Cherny, Stacey S., Chinthapalli, Krishna, Coffey, Alison J., Compston, Alastair, Coppola, Antonietta, Cossette, Patrick, Craig, John J., de Haan, Gerrit-Jan, De Jonghe, Peter, de Kovel, Carolien G. F., Delanty, Norman, Depondt, Chantal, Devinsky, Orrin, Dlugos, Dennis J., Doherty, Colin P., Elger, Christian E., Eriksson, Johan G., Ferraro, Thomas N., Feucht, Martha, Francis, Ben, Franke, Andre, French, Jacqueline A., Freytag, Saskia, Gaus, Verena, Geller, Eric B., Gieger, Christian, Glauser, Tracy, Glynn, Simon, Goldstein, David B., Gui, Hongsheng, Guo, Youling, Haas, Kevin F., Hakonarson, Hakon, Hallmann, Kerstin, Haut, Sheryl, Heinzen, Erin L., Helbig, Ingo, Hengsbach, Christian, Hjalgrim, Helle, Iacomino, Michele, Ingason, Andrés, Jamnadas-Khoda, Jennifer, Johnson, Michael R., Kälviäinen, Reetta, Kantanen, Anne-Mari, Kasperavičiūte, Dalia, Kasteleijn-Nolst Trenite, Dorothee, Kirsch, Heidi E., Knowlton, Robert C., Koeleman, Bobby P. C., Krause, Roland, Krenn, Martin, Kunz, Wolfram S., Kuzniecky, Ruben, Kwan, Patrick, Lal, Dennis, Lau, Yu-Lung, Lehesjoki, Anna-Elina, Lerche, Holger, Leu, Costin, Lieb, Wolfgang, Lindhout, Dick, Lo, Warren D., Lopes-Cendes, Iscia, Lowenstein, Daniel H., Malovini, Alberto, Marson, Anthony G., Mayer, Thomas, McCormack, Mark, Mills, James L., Mirza, Nasir, Moerzinger, Martina, Møller, Rikke S., Molloy, Anne M., Muhle, Hiltrud, Newton, Mark, Ng, Ping-Wing, Nöthen, Markus M., Nürnberg, Peter, O’Brien, Terence J., Oliver, Karen L.
Published in Nature communications (10.12.2018)

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De Novo Coding Variants Are Strongly Associated with Tourette Disorder

by Willsey, A. Jeremy, Yu, Dongmei, King, Robert A., Dietrich, Andrea, Xing, Jinchuan, Richer, Petra, Smith, Louw, Dong, Shan, Samocha, Kaitlin E., Bohnenpoll, Julia, Bromberg, Yana, Brown, Lawrence W., Cheon, Keun-Ah, Coffey, Barbara J., Deng, Li, Dong, Shan, Elzerman, Lonneke, Fernandez, Thomas V., Fründt, Odette, Garcia-Delgar, Blanca, Gedvilaite, Erika, Grice, Dorothy E., Hagstrøm, Julie, Hedderly, Tammy, Heiman, Gary A., Heyman, Isobel, Hoekstra, Pieter J., Hong, Hyun Ju, Ibanez-Gomez, Laura, Kim, Young Key, Kim, Young-Shin, King, Robert A., Koh, Yun-Joo, Kook, Sodahm, Kuperman, Samuel, Lamerz, Andreas, Ludolph, Andrea G., Lühr da Silva, Claudia, Madruga-Garrido, Marcos, Mir, Pablo, Münchau, Alexander, Murphy, Tara L., Nasello, Cara, Openneer, Thaïra J.C., Plessen, Kerstin J., Richer, Petra, Roessner, Veit, Sanders, Stephan, Smith, Louw, Song, Dong-Ho, State, Matthew W., Stolte, Anne Marie, Sun, Nawei, Tischfield, Jay A., Tübing, Jennifer, Visscher, Frank, Walker, Michael F., Wanderer, Sina, Wang, Shuoguo, Willsey, A. Jeremy, Woods, Martin, Xing, Jinchuan, Zhang, Yeting, Zhou, Anbo, Zinner, Samuel H., Batterson, James R., Berlin, Cheston, Bruun, Ruth D., Budman, Cathy L., Cath, Danielle C., Chouinard, Sylvain, Coppola, Giovanni, Cox, Nancy J., Darrow, Sabrina, Davis, Lea K., Freimer, Nelson B., Grados, Marco A., Hirschtritt, Matthew E., Illmann, Cornelia, Kurlan, Roger, Lyon, Gholson J., Malaty, Irene A., Mathews, Carol A., Neale, Benjamin M., Okun, Michael S., Osiecki, Lisa, Posthuma, Danielle, Ramensky, Vasily, Robertson, Mary M., Rouleau, Guy A., Sandor, Paul, Singer, Harvey S., Yu, Dongmei, Neale, Benjamin M., Coppola, Giovanni, Mathews, Carol A., Tischfield, Jay A., Scharf, Jeremiah M., State, Matthew W., Heiman, Gary A.
Published in Neuron (Cambridge, Mass.) (03.05.2017)

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Genome-Wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome

by Jain, Pritesh, Yang, Zhiyu, Yu, Dongmei, Tumer, Zeynep, Hartmann, Andreas, Müller-Vahl, Kirsten R., Boomsma, Dorret I., Wolanczyk, Tomasz, Nemoda, Zsofia, Padmanabhuni, Shanmukha S., Grice, Dorothy, Glennon, Jeffrey, Stefansson, Hreinn, Stamatoyannopoulos, John A., Benaroya-Milshtein, Noa, Cardona, Francesco, Heyman, Isobel, Mir, Pablo, Munchau, Alexander, Plessen, Kerstin J., Roessner, Veit, Martino, Davide, Barr, Cathy L., Batterson, James R., Budman, Cathy L., Coppola, Giovanni, Darrow, Sabrina, Freimer, Nelson B., Grados, Marco A., Greenberg, Erica, Huang, Alden Y., Illmann, Cornelia, Kurlan, Roger, Leckman, James F., Malaty, Irene A., McMahon, William M., Neale, Benjamin M., Osiecki, Lisa, Rouleau, Guy A., Sul, Jae Hoon, Androutsos, Christos, Basha, Entela, Farkas, Luca, Janik, Piotr, Kapisyzi, Mira, Karagiannidis, Iordanis, Koumoula, Anastasia, Nagy, Peter, Puchala, Joanna, Szymanska, Urszula, Apter, Alan, Bodmer, Benjamin, Bognar, Emese, Buse, Judith, Fremer, Carolin, Garcia-Delgar, Blanca, Hagen, Annelieke, Hagstrøm, Julie, Madruga-Garrido, Marcos, Silvestri, Paola Rosaria, Skov, Liselotte, Steinberg, Tamar, Turner, Victoria L., Alexander, John, Aranyi, Tamas, Fan, Siyan, Forde, Natalie J., Gerasch, Sarah, Kanaan, Ahmad S., Möller, Harald E., Poelmans, Geert, Pouwels, Petra J.W., Rizzo, Francesca, Veltman, Dick J., van der Werf, Ysbrand D., Widomska, Joanna, Zilhäo, Nuno R., Brown, Lawrence W., Cheon, Keun-Ah, Fernandez, Thomas V., Kim, Eun-Joo, Kim, Young Key, Koh, Yun-Joo, Kook, Sodahm, Kuperman, Samuel, Maras, Athanasios, Murphy, Tara L., Shin, Eun-Young, Song, Dong-Ho, State, Matthew W., Visscher, Frank, Heiman, Gary A., Willsey, A. Jeremy, Dietrich, Andrea, Davis, Lea K., Crowley, James J., Scharf, Jeremiah M., Georgitsi, Marianthi, Hoekstra, Pieter J., Paschou, Peristera
Published in Biological psychiatry (1969) (15.07.2024)

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De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis

by Wang, Sheng, Mandell, Jeffrey D., Kumar, Yogesh, Sun, Nawei, Nasello, Cara, Dong, Shan, Duhn, Clif, Zhao, Xin, Yang, Zhiyu, Padmanabhuni, Shanmukha S., Yu, Dongmei, King, Robert A., Dietrich, Andrea, Dahl, Niklas, Huang, Alden Y., Neale, Benjamin M., Mathews, Carol A., Abdulkadir, Mohamed, Arbelaez, Juan, Bodmer, Benjamin, Coffey, Barbara J., Deng, Li, Dietrich, Andrea, Duhn, Clif, Fernandez, Thomas V., Fremer, Carolin, Gilbert, Donald L., Grice, Dorothy E., Hagstrøm, Julie, Hedderly, Tammy, Heiman, Gary A., Hong, Hyun Ju, Huyser, Chaim, Kim, Eun-Joo, Kim, Young Key, Kim, Young-Shin, King, Robert A., Kuperman, Samuel, Mandell, Jeffrey D., Maras, Athanasios, Müller-Vahl, Kirsten, Münchau, Alexander, Nasello, Cara, Plessen, Kerstin J., Poisner, Hannah, Roessner, Veit, Sanders, Stephan J., Song, Jungeun, State, Matthew W., Tischfield, Jay A., Wanderer, Sina, Wang, Sheng, Willsey, A Jeremy, Xing, Jinchuan, Zhang, Yeting, Zhao, Xin, Zinner, Samuel H., Androutsos, Christos, Barta, Csaba, Farkas, Luca, Janik, Piotr, Karagiannidis, Iordanis, Koumoula, Anastasia, Nagy, Peter, Rizzo, Renata, Szymanska, Urszula, Tarnok, Zsanett, Tsironi, Vaia, Zekanowski, Cezary, Batterson, James R., Berlin, Cheston, Bruun, Ruth D., Budman, Cathy L., Chouinard, Sylvain, Coppola, Giovanni, Darrow, Sabrina, Dion, Yves, Freimer, Nelson B., Grados, Marco A., Hirschtritt, Matthew E., Kurlan, Roger, Lyon, Gholson J., Malaty, Irene A., MacMahon, William M., Neale, Benjamin M., Pauls, David L., Ramensky, Vasily, Robertson, Mary M., Scharf, Jeremiah M., Singer, Harvey S., Smit, Jan, Sul, Jae-Hoon, Yu, Dongmei, Fernandez, Thomas V., De Rubeis, Silvia, Xing, Jinchuan, Tischfield, Jay A., Paschou, Peristera, Willsey, A. Jeremy, State, Matthew W.
Published in Cell reports (Cambridge) (25.09.2018)

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