Identification of (3R)-7-Hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)- 3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro- 3-isoquinolinecarboxamide as a Novel Potent and Selective Opioid κ Receptor Antagonist
Thomas, James B, Atkinson, Robert N, Vinson, N. Ariane, Catanzaro, Jennifer L, Perretta, Carin L, Fix, Scott E, Mascarella, S. Wayne, Rothman, Richard B, Xu, Heng, Dersch, Christina M, Cantrell, Buddy E, Zimmerman, Dennis M, Carroll, F. Ivy
Published in Journal of medicinal chemistry (03.07.2003)
Published in Journal of medicinal chemistry (03.07.2003)
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Identification of the First trans-(3R,4R)- Dimethyl-4-(3-hydroxyphenyl)piperidine Derivative To Possess Highly Potent and Selective Opioid κ Receptor Antagonist Activity
Thomas, James B, Atkinson, Robert N, Rothman, Richard B, Fix, Scott E, Mascarella, S. Wayne, Vinson, N. Ariane, Xu, Heng, Dersch, Christina M, Lu, Y. -F, Cantrell, Buddy E, Zimmerman, Dennis M, Carroll, F. Ivy
Published in Journal of medicinal chemistry (16.08.2001)
Published in Journal of medicinal chemistry (16.08.2001)
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Discovery of an Opioid κ Receptor Selective Pure Antagonist from a Library of N-Substituted 4β-Methyl-5-(3-hydroxyphenyl)morphans
Thomas, James B, Atkinson, Robert N, Namdev, Nivedita, Rothman, Richard B, Gigstad, Kenneth M, Fix, Scott E, Mascarella, S. Wayne, Burgess, Jason P, Vinson, N. Ariane, Xu, Heng, Dersch, Christina M, Cantrell, Buddy E, Zimmerman, Dennis M, Carroll, F. Ivy
Published in Journal of medicinal chemistry (01.08.2002)
Published in Journal of medicinal chemistry (01.08.2002)
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